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Journal Article
Science, ISSN 0036-8075, 8/1999, Volume 285, Issue 5430, pp. 1074 - 1077
Isoleucyl-transfer RNA (tRNA) synthetase (IleRS) joins Ile to tRNA$^{Ile}$ at its synthetic active site and hydrolyzes incorrectly acylated amino acids at its... 
Phosphates | Enzymes | RNA editing | Active sites | DNA | Crystals | Atoms | Amino acids | Reports | Nucleotides | Transfer RNA | REFINEMENT | MECHANISM | GENE | DNA-POLYMERASE-I | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | SITES | AMINOACYLATION | KLENOW FRAGMENT | TRANSFER-RNA-SYNTHETASE
Journal Article
Protein Science, ISSN 0961-8368, 05/2010, Volume 19, Issue 5, pp. 954 - 966
Journal Article
Protein Science, ISSN 0961-8368, 03/2018, Volume 27, Issue 3, pp. 672 - 680
Journal Article
Drug Discovery Today: Technologies, ISSN 1740-6749, 12/2013, Volume 10, Issue 4, pp. e509 - e515
Several advances in the fields of crystallography, molecular modeling, biophysical assays and chemistry are converging to making protein–protein interaction... 
Protein Binding | Proteins - chemistry | Small Molecule Libraries | Crystallization | Drug Design | Protein Interaction Mapping | Proteins | Analysis | Methods | Protein binding
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2013, Volume 21, Issue 14, pp. 4011 - 4019
Journal Article
Journal Article
Protein Science, ISSN 0961-8368, 02/2017, Volume 26, Issue 2, pp. 152 - 162
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 07/2019, Volume 27, Issue 13, pp. 2905 - 2913
Since the approval of ibrutinib for the treatment of B-cell malignancies in 2012, numerous clinical trials have been reported using covalent inhibitors to... 
Fragment screen | Bruton’s Tyrosine Kinase (BTK) | Computer aid drug design (CADD)
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 05/2016, Volume 26, Issue 10, p. 2459
Journal Article
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY, ISSN 0968-0896, 07/2019, Volume 27, Issue 13, pp. 2905 - 2913
Since the approval of ibrutinib for the treatment of B-cell malignancies in 2012, numerous clinical trials have been reported using covalent inhibitors to... 
ACTIVATION | DESIGN | CHEMISTRY, MEDICINAL | Fragment screen | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | Bruton's Tyrosine Kinase (BTK) | DISCOVERY | POTENT | B-CELL | GENE | CLONING | BTK | Computer aid drug design (CADD) | EXPRESSION | TEC FAMILY KINASES | Tyrosine