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2015, 2ND ED., DRUG DISCOVERY SERIES.14, ISBN 1439836507, Volume 14, 584
Phage Display in Biotechnology and Drug Discovery, Second Edition provides a comprehensive view of the impact and promise of phage display in drug discovery... 
Drug Discovery | Bacteriophages | Viral proteins | Microbial biotechnology | Pharmaceutical biotechnology | Affinity chromatography
Book
Nature Chemical Biology, ISSN 1552-4450, 01/2018, Volume 14, Issue 2, pp. 110 - 111
Journal Article
Cell, ISSN 0092-8674, 12/2015, Volume 163, Issue 6, pp. 1515 - 1526
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 08/2016, Volume 113, Issue 31, p. 8705
  A detailed understanding of the molecular mechanisms whereby ubiquitin (Ub) recognizes enzymes in the Ub proteasome system is crucial for understanding the... 
Proteins | Enzymes | Mutagenesis | Proteases | Molecular chemistry | Biochemistry | Binding sites
Journal Article
Nature, ISSN 0028-0836, 08/2014, Volume 512, Issue 7513, pp. 218 - 222
Journal Article
Journal Article
Science, ISSN 0036-8075, 2/2013, Volume 339, Issue 6119, pp. 590 - 595
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2017, Volume 23, Issue 1, pp. 60 - 68
Forward genetic screens with CRISPR-Cas9 genome editing enable high-resolution detection of genetic vulnerabilities in cancer cells. We conducted genome-wide... 
MEDICINE, RESEARCH & EXPERIMENTAL | RNF43 | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | CANCER | CELL BIOLOGY | ESSENTIAL GENES | INHIBITION | GROWTH | MUTATIONAL LANDSCAPE | WNT | RECEPTORS | Frizzled Receptors - antagonists & inhibitors | Neoplasm Transplantation | Oncogene Proteins - genetics | Pancreatic Neoplasms - metabolism | Colorectal Neoplasms - genetics | Humans | Carcinoma, Pancreatic Ductal - metabolism | Molecular Targeted Therapy | RNA, Messenger - metabolism | Carcinoma, Pancreatic Ductal - genetics | Adenocarcinoma - metabolism | Flow Cytometry | Organoids - metabolism | Clustered Regularly Interspaced Short Palindromic Repeats | Adenocarcinoma - genetics | Real-Time Polymerase Chain Reaction | Colorectal Neoplasms - metabolism | Frizzled Receptors - metabolism | Pancreatic Neoplasms - genetics | DNA-Binding Proteins - genetics | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Antibodies - pharmacology | Animals | Wnt Signaling Pathway - drug effects | Wnt Signaling Pathway - genetics | Cell Cycle Checkpoints - drug effects | Fluorescent Antibody Technique | Organoids - drug effects | Cell Line, Tumor | Mice | Care and treatment | Pancreatic cancer | Innovations | Development and progression | Genotype | Genetic engineering | Cellular signal transduction | Genetic aspects | Health aspects | Proteins | Viral antibodies | Genomics | Colorectal cancer | Antibodies | Genomes | Genetic screening | Cell proliferation | Adenocarcinoma | CRISPR | Therapy | Immunoglobulins | Wnt protein | Frizzled protein | Xenotransplantation | Colorectal carcinoma | Cell surface | Signaling | Receptors | Organoids | Xenografts | Inhibition | Mutation | Pancreas | Cancer | Tumors | Recombinant
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 2006, Volume 2, Issue 12, pp. 682 - 688
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2012, Volume 109, Issue 37, pp. 14779 - 14784
Total chemical synthesis was used to prepare the mirror image (D-protein) form of the angiogenic protein vascular endothelial growth factor (VEGF-A). Phage... 
Proteins | Bacteriophages | Molecules | Molecular structure | Ligands | Libraries | Chemical synthesis | Crystallography | Molecular chains | Crystal structure | CRYSTALLIZATION | SITE | DESIGN | D-PEPTIDE LIGANDS | CRYSTAL-STRUCTURE | ENANTIOMERS | VEGF | MULTIDISCIPLINARY SCIENCES | IMMUNOGLOBULIN-BINDING DOMAIN | RECEPTOR | IMAGE PHAGE DISPLAY | Surface Plasmon Resonance | Amino Acid Sequence | Epitope Mapping | Enzyme-Linked Immunosorbent Assay | Stereoisomerism | Vascular Endothelial Growth Factor A - chemical synthesis | Open Reading Frames | Bacterial Proteins - genetics | Models, Molecular | Molecular Sequence Data | Crystallography, X-Ray | Vascular Endothelial Growth Factor A - metabolism | Chromatography, High Pressure Liquid | Vascular Endothelial Growth Factor A - genetics | Vascular Endothelial Growth Factor A - chemistry | Multiprotein Complexes - metabolism | Multiprotein Complexes - chemistry | Mass Spectrometry | Circular Dichroism | Antagonists (Biochemistry) | Physiological aspects | Research | Vascular endothelial growth factor | SPECIFICITY | BASIC BIOLOGICAL SCIENCES | RESOLUTION | STOICHIOMETRY | CRYSTALLOGRAPHY | 60 APPLIED LIFE SCIENCES | PLASMONS | MIRRORS | MIXTURES | GROWTH FACTORS | SURFACE AREA | RESONANCE | AFFINITY | SYNTHESIS | SCREENS | PROTEINS | Biological Sciences | Physical Sciences | protein engineering | mirror image proteins | chemical protein synthesis | racemic X-ray crystallography
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 12/2016, Volume 22, Issue 43, pp. 6527 - 6537
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2004, Volume 101, Issue 34, pp. 12467 - 12472