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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2008, Volume 105, Issue 10, pp. 3921 - 3926
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e54712
A recent type 1 diabetes (T1D) clinical trial of rituximab (a B cell-depleting anti-CD20 antibody) achieved some therapeutic benefit in preserving C-peptide... 
DESTRUCTION | RECENT-ONSET | IMMUNOTHERAPY | MULTIDISCIPLINARY SCIENCES | BETA-CELLS | MONOCLONAL-ANTIBODY | TYPE-1 | PREVENTS | EXPRESSION | LYMPHOCYTE DEPLETION | ANTIGEN | Vaccines, DNA - genetics | Spleen - immunology | Insulin - immunology | Vaccines, DNA - immunology | Spleen - drug effects | Hyperglycemia - drug therapy | Vaccines, DNA - administration & dosage | CD4-Positive T-Lymphocytes - immunology | Female | Lymph Nodes - drug effects | Proinsulin - administration & dosage | Diabetes Mellitus, Type 1 - immunology | Insulin - genetics | Antibodies, Monoclonal - immunology | Proinsulin - immunology | Antigens, CD20 - immunology | B-Lymphocytes - cytology | Administration, Oral | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Hyperglycemia - immunology | Diabetes Mellitus, Type 1 - genetics | Pancreas - drug effects | Insulin - administration & dosage | Proinsulin - genetics | Lymph Nodes - immunology | Pancreas - immunology | Diabetes Mellitus, Type 1 - drug therapy | B-Lymphocytes - drug effects | Interleukin-4 - immunology | Drug Therapy, Combination - methods | Animals | B-Lymphocytes - immunology | Mice, Inbred NOD | Mice | CD4-Positive T-Lymphocytes - drug effects | Autoimmunity | Antigens | Type 1 diabetes | DNA | Vaccines | B cells | T cells | Health aspects | Insulin | Effectiveness | Diabetes mellitus | Rituximab | Reversing | Lymphocytes T | DNA vaccines | CD3 antigen | T cell receptors | Disease control | Lymph nodes | CD4 antigen | Beta cells | Prevention | Augmentation | Interleukin 4 | Depletion | Lymphocytes | Rodents | CD20 antigen | Pancreas | Deoxyribonucleic acid--DNA | Deoxyribonucleic acid | Lymphocytes B
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, p. e79383
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2013, Volume 50, pp. 77 - 82
Journal Article
FEBS Letters, ISSN 0014-5793, 2011, Volume 585, Issue 8, pp. 1223 - 1230
Thioredoxin-interacting protein (Txnip) knockout (TKO) mice exhibit impaired response to fasting. Herein, we showed that activation of adenine... 
Mitochondrial oxidation | Cellular AMP level | Glucose homeostasis | Glycogen storage | pyruvate dehydrogenase | AS160 | CAB39 | pyruvate dehydrogenase kinases | liver kinase B1 | AICAR monophosphate | thioredoxin-interacting protein | acetyl-CoA carboxylase | LKB1 | STRAD | STE20-related adaptor protein | Txnip knockout | PDH | PDKs | Akt substrate of 160 kDa | MARK1 | ACC | Txnip | 5-Aminoimidazole-4-carboxyamide ribonucleoside | adenine monophosphate-activated protein kinase | MAP/microtubule affinity-regulating kinase 1 | calcium binding protein 39 | TKO | AMPK | AICAR | ZMP | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | GLUCOSE-TRANSPORT | IDENTIFICATION | DEFICIENCY | CELL BIOLOGY | INSULIN | REGULATOR | BIOPHYSICS | GENE-EXPRESSION | TXNIP | AMP-Activated Protein Kinases - metabolism | Phosphorylation | Glucose Transporter Type 1 - metabolism | Muscle, Skeletal - metabolism | Insulin - blood | Aminoimidazole Carboxamide - pharmacology | Ribonucleotides - pharmacology | Glycogen - metabolism | Thioredoxins - genetics | Fasting - blood | Muscle, Skeletal - drug effects | Myocardium - metabolism | Thioredoxins - metabolism | Fasting - metabolism | Pyruvate Dehydrogenase Complex - metabolism | Signal Transduction | Adenosine Monophosphate - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Serine - metabolism | Blotting, Western | Hypoglycemic Agents - pharmacology | Mice, Knockout | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Aminoimidazole Carboxamide - analogs & derivatives | Glucose Transporter Type 1 - genetics | Glucose - metabolism | Mice | Enzyme Activation | glucose homeostasis | glycogen storage | mitochondrial oxidation | cellular AMP level
Journal Article
Journal Article
Clinical Immunology, ISSN 1521-6616, 2014, Volume 153, Issue 2, pp. 298 - 307
Abstract While previous reports have demonstrated the efficacy of regulatory T cell therapy in the prevention of diabetes, systemic immunocompromise and Treg... 
Allergy and Immunology | Therapy | Stability | Diabetes | Safety | Regulatory T cells | Viral infection | VIRUS-INFECTION | TGF-BETA | MELLITUS | IMMUNOLOGY | VIRAL-INFECTION | IMMUNE-RESPONSES | TRANSCRIPTION FACTOR FOXP3 | IMMUNOLOGICAL SELF-TOLERANCE | IN-VITRO GENERATION | AUTOIMMUNE-DISEASE | TRANSGENIC MICE | Forkhead Transcription Factors - immunology | Lymphocytic choriomeningitis virus - immunology | Tumor Necrosis Factor-alpha - metabolism | T-Lymphocytes, Regulatory - metabolism | Green Fluorescent Proteins - genetics | Adoptive Transfer | Diabetes Mellitus, Type 1 - complications | Interferon-gamma - metabolism | Lymphocytic Choriomeningitis - immunology | Diabetes Mellitus, Type 1 - therapy | Host-Pathogen Interactions - immunology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Lymphocytic Choriomeningitis - complications | Flow Cytometry | Time Factors | Forkhead Transcription Factors - metabolism | Tumor Necrosis Factor-alpha - immunology | CD8-Positive T-Lymphocytes - metabolism | Interleukin-10 - metabolism | Lymphocytic choriomeningitis virus - physiology | Diabetes Mellitus, Type 1 - immunology | Green Fluorescent Proteins - metabolism | Acute Disease | Lymphocytic Choriomeningitis - virology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Mice, Transgenic | Forkhead Transcription Factors - genetics | Animals | Interferon-gamma - immunology | Mice | T-Lymphocytes, Regulatory - transplantation | CD8-Positive T-Lymphocytes - immunology | Interleukin-10 - immunology | Virus diseases | Antiviral agents | T cells | Analysis | Diabetes therapy
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2014, Volume 55, Issue 1, pp. 24 - 32
Journal Article
Clinical Immunology, ISSN 1521-6616, 2010, Volume 135, pp. S18 - S18
Journal Article