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Frontiers in Immunology, ISSN 1664-3224, 2012, Volume 3
Investigations into the role of complement in ischemia/reperfusion (I/R) injury have identified common effector mechanisms that depend on the production of C5a... 
Complement | Reperfusion | Ischemia | MBL | Kidney | kidney | IMMUNOLOGY | complement | reperfusion | ischemia
Journal Article
Journal Article
Journal Article
Inflammation and Allergy - Drug Targets, ISSN 1871-5281, 2009, Volume 8, Issue 3, pp. 236 - 246
C3a and C5a, the small (~10KDa) cleavage fragments released by complement activation, are potent mediators of inflammation. They are anaphylatoxins and act as... 
C3a | C3a receptor | C5a receptor | Innate and adaptive immune regulation | Anaphylatoxins | Inflammation | Local synthesis of complement | C5a
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, pp. e72059 - e72059
Background: Ischemia/reperfusion injury of lower extremities and associated lung damage may result from thrombotic occlusion, embolism, trauma, or surgical... 
ISCHEMIA-REPERFUSION INJURY | SKELETAL-MUSCLE | PLASMA KALLIKREIN | HEREDITARY ANGIOEDEMA | ENDOTHELIAL GLYCOCALYX | LIMB ISCHEMIA | MULTIDISCIPLINARY SCIENCES | FOLLOW INTESTINAL ISCHEMIA | SYSTEMIC INFLAMMATORY RESPONSE | LEUKOCYTE ADHESION | COMPLEMENT INHIBITOR | Chemokines - blood | Cadherins - metabolism | Rats, Wistar | Apoptosis - drug effects | Muscles - pathology | Antigens, CD - metabolism | Intercellular Signaling Peptides and Proteins - blood | Immunoglobulin M - metabolism | Hindlimb - physiopathology | Lung - metabolism | Muscles - metabolism | Cytokines - blood | Edema - prevention & control | Lung - pathology | Inflammation Mediators - blood | Rats | Edema - metabolism | Animals | Complement C1 Inhibitor Protein - pharmacology | Reperfusion Injury - prevention & control | Hindlimb - blood supply | Lung - drug effects | Muscles - drug effects | Reperfusion Injury - physiopathology | Hindlimb - drug effects | Receptor, Bradykinin B1 - metabolism | Fibrin - metabolism | Microscopy, Fluorescence | Immunoglobulin G - metabolism | Enzymes | Fibrin | Ischemia | Lung diseases | Therapeutics | Hydrolases | Homeopathy | Materia medica and therapeutics | Occlusion | Heart | Complement receptors | Femoral artery | Femur | Transplants & implants | Lung | Complement | Blood | Reperfusion | Immunology | Restoration | Esterase | Rodents | Surgery | Cascades | Bradykinin | Inhibition | Damage | Extremities | Deposition | Heparan sulfate | Edema | Deprivation | Immunoglobulins | Cytokines | Muscles | Inflammation | Permeability | Cadherin | Sodium chloride | Trauma | Morbidity | Embolism | Blood flow | Endothelium | Complement component C1 | Complement activation | Injury prevention | Inhibitors | Plasma levels | Viability | Binding sites | Apoptosis | Index Medicus
Journal Article
JOURNAL OF IMMUNOLOGY, ISSN 0022-1767, 09/2017, Volume 199, Issue 5, pp. 1835 - 1845
Journal Article