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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, ISSN 0066-4804, 03/2018, Volume 62, Issue 3
Fungal infections frequently affect immunodeficient individuals and are estimated to kill 1.35 million people per annum. Azole antifungals target the... 
lanosterol 14 alpha-demethylase | CYTOCHROME-P450 | SUBSTITUTION | ASPERGILLUS-FUMIGATUS | REDUCED SUSCEPTIBILITY | voriconazole | CROSS-RESISTANCE | MICROBIOLOGY | itraconazole | CYP51A | antifungal resistance | CYP51 | fungal infections | X-ray crystallography | fluconazole | AMINO-ACID | drug resistance mechanisms | AZOLE RESISTANCE | PHARMACOLOGY & PHARMACY | BINDING
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0167485
Azole antifungals, known as demethylase inhibitors (DMIs), target sterol 14 alpha-demethylase (CYP51) in the ergosterol biosynthetic pathway of fungal... 
MYCOSPHAERELLA-GRAMINICOLA | CYTOCHROME-P450 | ASPERGILLUS-FUMIGATUS | FUNGICIDES | MULTIDISCIPLINARY SCIENCES | AZOLE RESISTANCE | SENSITIVITY | TRIAZOLE RESISTANCE | MECHANISMS | MUTATIONS | CYP51 | Antifungal Agents - pharmacology | Catalytic Domain | 14-alpha Demethylase Inhibitors - chemistry | Molecular Conformation | Substrate Specificity | Saccharomyces cerevisiae - drug effects | Antifungal Agents - chemistry | Structure-Activity Relationship | Yeasts - drug effects | Yeasts - enzymology | Azoles - pharmacology | Agrochemicals - pharmacology | Azoles - chemistry | Microbial Sensitivity Tests | 14-alpha Demethylase Inhibitors - pharmacology | Protein Binding | Saccharomyces cerevisiae - enzymology | Molecular Structure | Sterol 14-Demethylase - metabolism | Sterol 14-Demethylase - chemistry | Binding Sites | Agrochemicals - chemistry | Cytochrome | Yeast | Fungicides | Hydrophobicity | Enantiomers | Proteins | Fungi | Antifungal activity | Agrochemicals | Sterols | Crop yield | Crystal structure | Recombinant | Prochloraz | Pathogens | Agricultural chemicals | Ergosterol | Lanosterol | Enzymes | Plants (botany) | Difenoconazole | Crop science | Tebuconazole | Crops | Pesticides | Crop protection | Dentistry | Disease control | Mutants | Membrane proteins | Fluquinconazole | Food security | Crop diseases | Mutation | Binding sites | Structure-function relationships
Journal Article
TSITOLOGIYA, ISSN 0041-3771, 1991, Volume 33, Issue 4, pp. 84 - 84
Intracellular distribution of labeled cotoran was studied. H-3-cotoran was shown to penetrate through the nuclear membrane to accumulate unevently in the... 
K FQ CYTOLOGY & HISTOLOGY | CYTOLOGY & HISTOLOGY
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, p. e0167485
Azole antifungals, known as demethylase inhibitors (DMIs), target sterol 14[alpha] -demethylase (CYP51) in the ergosterol biosynthetic pathway of fungal... 
Agricultural chemicals | Microbial enzymes | Plants, Protection of | Yeast fungi | Antifungal agents | Physiological aspects | Research
Journal Article
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