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Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. 2656 - 2656
Chromatin remodeling proteins are frequently dysregulated in human cancer, however little is known about how they control tumorigenesis. The NAD-dependent... 
Journal Article
The Oncologist, ISSN 1083-7159, 05/2016, Volume 21, Issue 5, pp. 594 - 599
摘要 背景 . 在胆管癌诊断和分类中存在的挑战使得这种高度侵袭性恶性肿瘤的真实发病率难以量化。 方法 . 我们对监测、流行病学及预后 (SEER) 项目中的数据进行了分析, 评估1973‐2012年间肝内和肝外胆管癌年龄标化发病率的长期变化趋势 (根据系统编码误差校正) 。由于肝内胆管癌 (ICC)... 
Trend | Extrahepatic cholangiocarcinoma | Cancer of unknown primary | Epidemiology | Intrahepatic cholangiocarcinoma | Incidence | UNITED-STATES | TARGETED THERAPY | MORTALITY | DIAGNOSIS | GUIDELINES | CLASSIFICATION | BILIARY-TRACT | ONCOLOGY | UNKNOWN PRIMARY SITE | LIVER | MUTATIONS | United States - epidemiology | Cholangiocarcinoma - epidemiology | Humans | Middle Aged | Male | Neoplasms, Unknown Primary - epidemiology | Bile Duct Neoplasms - epidemiology | Aged, 80 and over | Adult | Bile Ducts, Intrahepatic | Female | Aged | Index Medicus | Hepatobiliary
Journal Article
Nature, ISSN 0028-0836, 01/2006, Volume 439, Issue 7073, pp. 208 - 211
Journal Article
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7516, pp. 110 - 114
Mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 are among the most common genetic alterations in intrahepatic cholangiocarcinoma (IHCC), a deadly liver... 
PROGENITORS | INTRAHEPATIC CHOLANGIOCARCINOMA | HOMEOSTASIS | LIVER-REGENERATION | MULTIDISCIPLINARY SCIENCES | MUTATION | GROWTH | MICE | PROLIFERATION | EXPRESSION | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Hepatocyte Nuclear Factor 4 - antagonists & inhibitors | Humans | ras Proteins - metabolism | Hepatocytes - pathology | Male | Hepatocytes - metabolism | Bile Duct Neoplasms - enzymology | Cell Differentiation - genetics | Neoplasm Metastasis | Hepatocyte Nuclear Factor 4 - biosynthesis | Female | Bile Duct Neoplasms - genetics | Cell Lineage - genetics | Cholangiocarcinoma - enzymology | Disease Models, Animal | Cell Division - genetics | Proto-Oncogene Proteins - metabolism | Hepatocyte Nuclear Factor 4 - metabolism | Bile Ducts, Intrahepatic - pathology | Mutant Proteins - genetics | Isocitrate Dehydrogenase - genetics | Mice, Transgenic | Mutant Proteins - metabolism | Proto-Oncogene Proteins - genetics | Hepatocyte Nuclear Factor 4 - genetics | Mutation - genetics | Bile Ducts, Intrahepatic - enzymology | Cholangiocarcinoma - pathology | Animals | Cholangiocarcinoma - genetics | Stem Cells - pathology | Isocitrate Dehydrogenase - metabolism | Glutarates - metabolism | Mice | Bile Duct Neoplasms - pathology | Hepatocytes - enzymology | Index Medicus | Càncer | Diferenciació cel·lular | Gallbladder diseases | Metabolisme | Cell diferentiation | Metabolism | Malalties de la vesícula biliar | Cancer
Journal Article
The EMBO Journal, ISSN 0261-4189, 07/2006, Volume 25, Issue 14, pp. 3257 - 3263
Journal Article
Journal Article
Cancer Discovery, ISSN 2159-8274, 07/2016, Volume 6, Issue 7, pp. 727 - 739
Journal Article
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2006, Volume 203, Issue 11, pp. 2413 - 2418
Proper activation of nuclear factor (NF)-kappa B transcription factors is critical in regulating fundamental biological processes such as cell survival and... 
PATHWAYS | MEDICINE, RESEARCH & EXPERIMENTAL | BAFF | ACTIVATION | COMPLEX | DOMAIN | FACTOR-3 | NF-KAPPA-B2 | KINASE |