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SCIENTIFIC REPORTS, ISSN 2045-2322, 03/2019, Volume 9, Issue 1, pp. 3758 - 10
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11, p. e112142
Journal Article
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 7, p. e0181374
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, p. e22181
Retinitis pigmentosa (RP) is a heterogeneous group of inherited neurodegenerative diseases affecting photoreceptors and causing blindness. Many human cases are... 
POLY(ADP-RIBOSE) POLYMERASE | APOPTOSIS | CLINICAL EXPRESSION | MULTIDISCIPLINARY SCIENCES | MUTATION | MODEL | TRANSGENIC RAT | RETINITIS-PIGMENTOSA | CALPASTATIN | PROTEASE CALPAIN | DEGENERATION | Calpain - metabolism | Caspase 9 - metabolism | Oxidative Stress | Humans | Caspase 3 - metabolism | Rats, Mutant Strains | Cell Shape | Cell Death | Animals, Newborn | Biomarkers - metabolism | Calcium-Binding Proteins - metabolism | In Situ Nick-End Labeling | Rats, Transgenic | Cytochromes c - metabolism | Rats | Photoreceptor Cells, Vertebrate - cytology | Mutation - genetics | Photoreceptor Cells, Vertebrate - enzymology | Protein Transport | Poly Adenosine Diphosphate Ribose - metabolism | Poly(ADP-ribose) Polymerases - metabolism | Animals | Rhodopsin - genetics | Staining and Labeling | DNA Damage | Enzyme Activation | Cytochrome c | Nervous system diseases | Rhodopsin | Cell death | DNA damage | Calpain | Genetic aspects | Biochemistry | Sugars | Monosaccharides | Cytochrome | Calpastatin | Retinitis pigmentosa | Poly(ADP-ribose) | Transgenic | Retina | Activation | ADP | Cell activation | Neurodegeneration | Ribose | Protein folding | Degeneration | Protein transport | Polymers | Damage accumulation | Deoxyribonucleic acid--DNA | Phosphodiesterase | Neurodegenerative diseases | Mortality | Poly(ADP-ribose) polymerase | Mutants | Neurological diseases | Polymerase | Poly(ADP-ribose) Polymerase 1 | Blindness | Retinal degeneration | Photoreceptors | Retinitis | Mutation | Apoptosis | poly(ADP-ribose) polymerase 1 | retinal degeneration | Clinical Medicine | Ophthalmology | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Oftalmologi | Deoxyribonucleic acid | DNA
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, Issue 1, p. 39537
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, p. e15495
Retinitis pigmentosa (RP) is a group of inherited neurodegenerative diseases affecting photoreceptors and causing blindness in humans. Previously, excessive... 
PHOTORECEPTOR CELL-DEATH | CROSS-TALK | APOPTOSIS-INDUCING FACTOR | EXCESSIVE ACTIVATION | BIOLOGY | POLY(ADP-RIBOSE) POLYMERASE GENE | MOUSE RETINA | GUANOSINE-MONOPHOSPHATE | RETINITIS-PIGMENTOSA | BETA-SUBUNIT | MICE LACKING | Retina - metabolism | Humans | Cyclic Nucleotide Phosphodiesterases, Type 6 - antagonists & inhibitors | Male | Mice, 129 Strain | Retina - enzymology | Female | Electroretinography | In Situ Nick-End Labeling | Cyclic Nucleotide Phosphodiesterases, Type 6 - metabolism | Retinal Degeneration - genetics | Tomography, Optical Coherence | Retina - physiopathology | Phosphodiesterase Inhibitors - pharmacology | Retinitis Pigmentosa - genetics | Blotting, Western | Mice, Inbred C3H | Mice, Knockout | Retinitis Pigmentosa - enzymology | Poly(ADP-ribose) Polymerases - metabolism | Animals | Poly(ADP-ribose) Polymerases - genetics | Cyclic GMP - metabolism | Purinones - pharmacology | Mice | Photoreceptor Cells, Vertebrate - metabolism | Poly (ADP-Ribose) Polymerase-1 | Retinal Degeneration - pathology | Retinal Degeneration - enzymology | Retinitis Pigmentosa - pathology | Apoptosis | Enzymes | Nervous system diseases | Cell death | Blindness | Physiological aspects | Retinal degeneration | Genetic aspects | Comparative analysis | Sugars | Monosaccharides | Retinitis pigmentosa | Retina | Homology | ADP | Neurodegeneration | Ribose | Rodents | Degeneration | Inhibition | Genotypes | Phosphodiesterase | Neurodegenerative diseases | Mortality | Poly(ADP-ribose) polymerase | Cultures | Histology | Electroretinograms | Neurological diseases | Polymerase | Poly(ADP-ribose) Polymerase 1 | Isoforms | Photoreceptors | In vivo methods and tests | Retinitis | Mutation | Animal models | Clinical Medicine | Ophthalmology | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Oftalmologi
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 10/2015, Volume 72, Issue 20, pp. 3953 - 3969
Journal Article
Journal of Extracellular Vesicles, 01/2018, Volume 7, pp. 159 - 159
Background: Several degenerative eye diseases, such a retinitis pigmentosa (RP), age-related macular degeneration and diabetic retinopathy, are associated with... 
Explants | Diabetic retinopathy | Flow cytometry | Rhodopsin | CD9 antigen | Retinopathy | Retinitis pigmentosa | Diabetes mellitus | Retina | Epithelium | Electron microscopy | Retinal pigment epithelium | Macular degeneration | Nanoparticles | Vesicles | Eye diseases | Photoreceptors | Physiology | Retinitis | Age
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 13, pp. E2997 - E3006
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 13, p. E2997
Inherited retinal degeneration (RD) is a devastating and currently untreatable neurodegenerative condition that leads to loss of photoreceptor cells and... 
Drug delivery systems | Medical treatment | Guanosine | Medical services | Retina | Pharmacology | Drug delivery | Analogs | Heterogeneity | Cell activation | Cell death | Neurodegeneration | Cyclic GMP | Blindness | Retinal degeneration | Eye diseases | Degeneration | Apoptosis
Journal Article