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PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0181585
Journal Article
eLife, ISSN 2050-084X, 04/2018, Volume 7
Potent, selective and broadly characterized small molecule modulators of protein function (chemical probes) are powerful research reagents. The pharmaceutical... 
Target validation | chemical biology | Chemical probes | Open Science | biochemistry | DRUG DISCOVERY | BIOLOGY | INHIBITORS | CRISPR | Medical research | Research & development--R&D | Genomics | Biochemistry | Biology | Kinases | Proteins | Consortia | Chemistry | Quality | Pharmacy | Pharmaceutical industry | Probes | Pharmaceutical sciences | Cancer
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 05/2019, Volume 62, Issue 10, pp. 4915 - 4935
Anaplastic lymphoma kinase (ALK), a member of the receptor tyrosine kinase family, is predominantly expressed in the brain and implicated in neuronal... 
REFINEMENT | TRANSPORT | DESIGN | IMPACT | CHEMISTRY, MEDICINAL | C-MET | BARRIER | PROLIFERATION | PF-2341066 | RECEPTOR TYROSINE KINASE | P-GLYCOPROTEIN
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2017, Volume 486, Issue 3, pp. 626 - 631
Journal Article
Journal Article
Biochem. 47:13514,2008, ISSN 0006-2960, 05/2009, Volume 47, Issue 51
Nitrilases are a large and diverse family of nonpeptidic C-N hydrolases. The mammalian genome encodes eight nitrilase enzymes, several of which remain poorly... 
HYDROLASES | Other,CHEM, BIO | NEOPLASMS | SUBSTRATES | CRYSTAL STRUCTURE | CRYSTALLOGRAPHY | MATERIALS SCIENCE | DISCRIMINATORS | PROBES | ENZYMES | GENES | VERTEBRATES | TARGETS | RESIDUES | FUNCTIONALS
Journal Article