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1. Full Text In Vivo Molecular Imaging
by Saji, Hideo
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 10, pp. 1605 - 1615
molecular imaging | imaging probe | photoacoustic imaging | nuclear medical imaging | optical imaging | radiotheranostic | Molecular imaging | Nuclear medical imaging | Optical imaging | Radiotheranostic | Photoacoustic imaging | Imaging probe | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Molecular Probes | Molecular Imaging | Animals | Humans | Fluorescent Dyes | Neuroimaging | Brain | Target recognition | Molecular structure | Peptides | Brain tumors | Fluorescence | Fluorescent indicators | Tissues | Proteins | Computed tomography | Atherosclerosis | Infrared imaging | Nerves | Tomography | Pancreas | Probes | Alzheimer's disease | Plaques | Photon emission | Fluoroscopic imaging | Image resolution | Medical imaging | Positron emission | I.R. radiation | Single photon emission computed tomography | Biological activity | Emissions | Tau protein | Arteriosclerosis | Emission measurements | Sympathetic nerves | β-Amyloid | In vivo methods and tests | Kinetics | Positron emission tomography | Tumors | Index Medicus
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2. Full Text Molecular Approaches to the Treatment, Prophylaxis, and Diagnosis of Alzheimer’s Disease: Novel PET/SPECT Imaging Probes for Diagnosis of Alzheimer’s Disease
by Ono, Masahiro and Saji, Hideo
Journal of pharmacological sciences, ISSN 1347-8613, 2012, Volume 118, Issue 3, pp. 338 - 344
positron-emission tomography (PET) | single-photon emission computed tomography (SPECT) | Alzheimer’s disease | senile plaque | neurofibrillary tangle | Alzheimer's disease | Positron-emission tomography (PET) | Neurofibrillary tangle | Senile plaque | Single-photon emission computed tomography (SPECT) | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Tomography, Emission-Computed, Single-Photon - methods | Animals | Plaque, Amyloid - diagnostic imaging | Humans | Alzheimer Disease - therapy | Neurofibrillary Tangles - diagnostic imaging | Alzheimer Disease - diagnostic imaging | Positron-Emission Tomography - methods | Index Medicus
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3. Full Text Central in Vivo Nicotinic Acetylcholine Receptor Imaging Agents for Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT)
by Ogawa, Mikako and Tsukada, Hideo and Hatano, Kentaro and Ouchi, Yasuomi and Saji, Hideo and Magata, Yasuhiro and eGraduate School of Pharmaceutical Sciences and aPhoton Medical Research Center and cNational Institute. for Longevity Sciences and Kyoto University and dMolecular Imaging Frontier Research Center and National Center for Geriatrics and Gerontology and Hamamatsu University School of Medicine
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2009, Volume 32, Issue 3, pp. 337 - 340
drug development | nicotinic receptor | positron emission tomography | imaging | Drug development | Nicotinic receptor | Positron emission tomography | Imaging | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Brain - metabolism | Brain - diagnostic imaging | Receptors, Nicotinic - metabolism | Animals | Iodine Radioisotopes | Radiopharmaceuticals - pharmacokinetics | Tomography, Emission-Computed, Single-Photon | Pyridines - pharmacokinetics | Azetidines - pharmacokinetics | Positron-Emission Tomography | Carbon Radioisotopes | Index Medicus
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4. Full Text Activatable Fluorescence Imaging of Macrophages in Cerebral Aneurysms Using Iron Oxide Nanoparticles Conjugated With Indocyanine Green
by Ikeda, Hiroyuki and Ishii, Akira and Sano, Kohei and Chihara, Hideo and Arai, Daisuke and Abekura, Yu and Nishi, Hidehisa and Ono, Masahiro and Saji, Hideo and Miyamoto, Susumu
Frontiers in neuroscience, ISSN 1662-4548, 04/2020, Volume 14, pp. 370 - 370
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Brain | Aneurysm | Inflammation | Fluorescent indicators | FDA approval | Macrophages | Arteries | Molecular weight | Nanoparticles | Microscopy | Iron oxides | Localization | Veins & arteries | macrophage | fluorescent imaging | inflammation | iron oxide nanoparticles | cerebral aneurysm | indocyanine green
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5. Full Text Quantitative analysis of pharmaceutical drug distribution in multiple organs by imaging mass spectrometry
by Takai, Nozomi and Tanaka, Yukari and Inazawa, Kazuhiro and Saji, Hideo
Rapid communications in mass spectrometry, ISSN 0951-4198, 07/2012, Volume 26, Issue 13, pp. 1549 - 1556
Spectroscopy | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Technology | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Raclopride - pharmacokinetics | Histological Techniques - methods | Dopamine Antagonists - pharmacokinetics | Linear Models | Male | Mice, Transgenic | Molecular Imaging - methods | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods | Tissue Distribution | Animals | Raclopride - analysis | Mice | Chromatography, Liquid - methods | Dopamine Antagonists - analysis | Index Medicus | Drugs | Reproduction | Imaging | Organs | Liquid chromatography | Mass spectrometry | Quantitative analysis | Pharmaceuticals
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6. Full Text Recent advances in molecular imaging probes for β-amyloid plaques
by Ono, Masahiro and Saji, Hideo
MedChemComm, ISSN 2040-2503, 3/2015, Volume 6, Issue 3, pp. 391 - 42
Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology
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7. Full Text Quantitative Analysis of Tissue Distribution of the B16BL6-Derived Exosomes Using a Streptavidin-Lactadherin Fusion Protein and Iodine-125-Labeled Biotin Derivative After Intravenous Injection in Mice
by Morishita, Masaki and Takahashi, Yuki and Nishikawa, Makiya and Sano, Kohei and Kato, Kana and Yamashita, Takuma and Imai, Takafumi and Saji, Hideo and Takakura, Yoshinobu
Journal of pharmaceutical sciences, ISSN 0022-3549, 02/2015, Volume 104, Issue 2, pp. 705 - 713
streptavidin | nanoparticles | pharmacokinetics | lactadherin | clearance | biomaterials | phospholipids | quantitative analysis | exosome | radioisotope | Nanoparticles | Lactadherin | Exosome | Streptavidin | Phospholipids | Clearance | Radioisotope | Pharmacokinetics | Biomaterials | Quantitative analysis | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Chemistry, Multidisciplinary | Science & Technology | Exosomes - metabolism | Tissue Distribution - physiology | Tissue Distribution - drug effects | Injections, Intravenous | Recombinant Fusion Proteins - analysis | Male | Recombinant Fusion Proteins - metabolism | Biotin - analysis | Iodine Radioisotopes - administration & dosage | Animals | Iodine Radioisotopes - metabolism | Melanoma, Experimental | Streptavidin - metabolism | Streptavidin - analysis | Protein Binding | Biotin - metabolism | Mice | Mice, Inbred BALB C | Iodine Radioisotopes - analysis | Biotin - administration & dosage | Recombinant Fusion Proteins - administration & dosage | Biotin | Biological products | Genetic vectors | Analysis | Index Medicus
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8. Full Text Application of radioisotopes for theranostics, a combination of diagnostics and therapy
by Saji, Hideo
Yakugaku zasshi, ISSN 0031-6903, 04/2015, Volume 135, Issue 4, pp. 551 - 556
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Diagnostic Imaging | Radioisotopes - therapeutic use | Humans | Drug Design | Index Medicus
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9. Full Text Accumulation of arginine-rich cell-penetrating peptides in tumors and the potential for anticancer drug delivery in vivo
by Nakase, Ikuhiko and Konishi, Yusuke and Ueda, Masashi and Saji, Hideo and Futaki, Shiroh
Journal of controlled release, ISSN 0168-3659, 04/2012, Volume 159, Issue 2, pp. 181 - 188
Arginine-rich cell-penetrating peptide | In vivo fluorescent imaging | Drug delivery | Tumor accumulation | Biodistribution | Doxorubicin | Pharmacology & Pharmacy | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Pharmaceutical technology. Pharmaceutical industry | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Doxorubicin - therapeutic use | Stereoisomerism | Humans | Cell-Penetrating Peptides - pharmacokinetics | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - administration & dosage | Drug Carriers - chemistry | tat Gene Products, Human Immunodeficiency Virus - chemistry | Tissue Distribution | Time Factors | Carrier Proteins - chemistry | Female | Antineoplastic Agents - pharmacokinetics | Oligopeptides - chemistry | Cell-Penetrating Peptides - chemistry | CHO Cells | Doxorubicin - administration & dosage | Cell Survival - drug effects | Cricetinae | Doxorubicin - pharmacokinetics | Xenograft Model Antitumor Assays | Microscopy, Confocal | Peptide Fragments - chemistry | Animals | Mice, Nude | Cell Proliferation - drug effects | Drug Carriers - pharmacokinetics | Mice | Mice, Inbred BALB C | HeLa Cells | Index Medicus | Tat protein | Antitumor agents | Glycosaminoglycans | Intravenous administration | imaging | Controlled release | Tumors
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10. Full Text Radioiodinated Peptidic Imaging Probes for in Vivo Detection of Membrane Type-1 Matrix Metalloproteinase in Cancers
by Kondo, Naoya and Temma, Takashi and Shimizu, Yoichi and Ono, Masahiro and Saji, Hideo and bDepartment of Investigative Radiology and aDepartment of Patho-Functional Bioanalysis and Kyoto University and Graduate School of Pharmaceutical Sciences and National Cerebral and Cardiovascular Center Research Institute
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2015, Volume 38, Issue 9, pp. 1375 - 1382
membrane type-1 matrix metalloproteinase (MT1-MMP) | peptide | in vivo imaging | Peptide | Membrane type-1 matrix metalloproteinase (MT1-MMP) | In vivo imaging | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Neoplasms - metabolism | Peptides - blood | Iodine Radioisotopes | Humans | Peptides - pharmacokinetics | Male | Matrix Metalloproteinase 14 - metabolism | Peptides - pharmacology | Diagnostic Imaging | Animals | Plasma - chemistry | Biomarkers, Tumor - metabolism | Cell Line, Tumor | Female | Mice | Mice, Inbred BALB C | Index Medicus
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