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SCIENTIFIC REPORTS, ISSN 2045-2322, 06/2019, Volume 9, Issue 1, pp. 8547 - 13
Growth retardation is an important side effect of glucocorticoid (GC)-based drugs, which are widely used in various preparations to treat many pediatric... 
SYSTEM | OVEREXPRESSION | DEXAMETHASONE | OVERGROWTH | CHONDROCYTES | MULTIDISCIPLINARY SCIENCES | KINASE HOMOLOGY DOMAIN | RECEPTOR-B NPR2 | HETEROZYGOUS MUTATIONS | EXPRESSION | CHILDREN | Phosphorylation | Animal models | Dexamethasone | Growth rate | Glucocorticoids | Cyclic GMP | Rodents | Extracellular signal-regulated kinase | Body length | C-Type natriuretic peptide
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 10332 - 10
Skeletal growth in mammals, which owes the growth of an individual, occurs at the growth plate and to observe and analyze its dynamic growth is of high... 
PATHWAY | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MICE | NATRIURETIC PEPTIDE | MICROSCOPY | CARTILAGE | Explants | Cell culture | Ulna | Fetuses | Growth plate | Bone growth | Chondrocytes | Organ culture | Bone (long) | Bone imaging | Bone (endochondral) | Elongation | C-Type natriuretic peptide
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2017, Volume 12, Issue 6, p. e0179213
The iodothyronine deiodinases are selenoenzymes that regulate the activity of thyroid hormone via specific inner- or outer-ring deiodination. In humans, type 1... 
RESPONSE ELEMENT | DNA-BINDING | GENE | LIVER-X | NUCLEAR RECEPTORS | T0901317 | MULTIDISCIPLINARY SCIENCES | RETINOIC-ACID | DIRECT REPEATS | THYROID-HORMONE RECEPTORS | TRANSCRIPTIONAL REGULATION | Gene Expression Regulation, Enzymologic - drug effects | Retinoid X Receptor alpha - metabolism | Humans | Liver - metabolism | Transcriptional Activation - drug effects | Hydrocarbons, Fluorinated - pharmacology | Liver X Receptors - metabolism | Gene Expression Regulation, Enzymologic - physiology | Sulfonamides - pharmacology | Cycloheximide - pharmacology | Hep G2 Cells | Receptors, Thyroid Hormone - metabolism | Receptors, Thyroid Hormone - genetics | HEK293 Cells | Retinoid X Receptor alpha - genetics | Transcriptional Activation - physiology | Iodide Peroxidase - genetics | Response Elements - physiology | Iodide Peroxidase - biosynthesis | Liver X Receptors - genetics | Liver | Genes | Mobility | Activation | Thyroid gland | Nucleotides | Assaying | Receptors | Control | Coding | Rodents | Transcription activation | Electrophoresis | Deoxyribonucleic acid--DNA | Thyroid | University graduates | Binding | Kidneys | Nutrition | Liver X receptors | Iodide peroxidase | Protein biosynthesis | Gene expression | Retinoid X receptors | Nuclear receptors | Promoters | Medicine | Cycloheximide | Hospitals | Thyroxine deiodinase | Hepatocytes | Protein synthesis | Electrophoretic mobility | Growth hormones | Ligands | Diabetes | Intracellular | Alzheimers disease | Endocrinology | Kidney transplantation | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2018, Volume 13, Issue 9, p. e0204172
Signaling by C-type natriuretic peptide (CNP) and its receptor, natriuretic peptide receptor-B, is a pivotal stimulator of endochondral bone growth. We... 
SYSTEM | MURINE MODEL | OVEREXPRESSION | BONE-GROWTH | EARLY DEATH | CNP | DYSPLASIAS | IMPAIRED SKELETAL GROWTH | MULTIDISCIPLINARY SCIENCES | RECEPTOR | MICE | Research | Gene mutations | Cartilage cells | Natriuretic peptides
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2017, Volume 127, Issue 11, pp. 4136 - 4147
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2018, Volume 13, Issue 3, p. e0194812
Journal Article
Journal Article
Journal Article
Journal Article
Endocrine Journal, ISSN 0918-8959, 2016
The objective of this study was to compare the safety and efficacy of high-dose and low-dose intravenous (iv) glucocorticoid (GC) therapy in patients with... 
Thyroid-associated ophthalmopathy | MRI | Intravenous glucocorticoid therapy | Graves' ophthalmopathy | STIR
Journal Article
Endocrinology, ISSN 0013-7227, 01/2012, Volume 153, Issue 1, pp. 492 - 500
Type 1 iodothyronine deiodinase (D1), a selenoenzyme that catalyzes the bioactivation of thyroid hormone, is expressed mainly in the liver. Its expression and... 
Journal Article
Journal Article