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1. Full Text Acceleration of cancer science with genome editing and related technologies
by Sakuma, Tetsushi and Yamamoto, Takashi
Cancer science, ISSN 1347-9032, 12/2018, Volume 109, Issue 12, pp. 3679 - 3685
cancer science | transcriptome editing | genome editing | base editing | CRISPR‐Cas9 | CRISPR-Cas9 | Life Sciences & Biomedicine | Oncology | Science & Technology | Epigenomics | Sequence Analysis, RNA | Neoplasms - genetics | Humans | Biomedical Research | Gene Editing - methods | Gene Expression Profiling | Epigenetic inheritance | Genetic aspects | Genomics | Cancer | CRISPR | RNA editing | Nucleotide sequence | Laboratories | DNA damage | Genes | Science | Genomes | Double-strand break repair | Chromosome rearrangements | Gene expression | Proteins | Chromosome translocations | Technological change | Proteomics | Epigenetics | Genetic engineering | Labeling | Deoxyribonucleic acid--DNA | Index Medicus | Review
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2. Full Text Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system
by Sakuma, Tetsushi and Nishikawa, Ayami and Kume, Satoshi and Chayama, Kazuaki and Yamamoto, Takashi
Scientific reports, ISSN 2045-2322, 06/2014, Volume 4, Issue 1, pp. 5400 - 5400
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic Engineering - methods | Clustered Regularly Interspaced Short Palindromic Repeats - genetics | Transfection - methods | Humans | Genetic Vectors - genetics | Genome, Human - genetics | Targeted mutagenesis | Gene silencing | CRISPR | Gene targeting | Mutagenesis | Transcription activation | Genomes | Nuclease | Ribonucleic acid--RNA | Expression vectors | Index Medicus
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3. Full Text Simple knockout by electroporation of engineered endonucleases into intact rat embryos
by Kaneko, Takehito and Sakuma, Tetsushi and Yamamoto, Takashi and Mashimo, Tomoji
Scientific reports, ISSN 2045-2322, 2014, Volume 4, Issue 1, pp. 6382 - 6382
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic Engineering - methods | Gene Targeting - methods | Zinc Fingers | Rats, Inbred F344 | Cells, Cultured | Rats | Male | Electroporation - methods | Embryo, Mammalian - metabolism | Endodeoxyribonucleases - genetics | Animals | Embryo Transfer | Embryo, Mammalian - cytology | CRISPR-Cas Systems | Endodeoxyribonucleases - metabolism | Female | Clustered Regularly Interspaced Short Palindromic Repeats - genetics | CRISPR | Electroporation | Genomes | Microinjection | Transcription | Endonuclease | Index Medicus
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4. Full Text MMEJ-assisted gene knock-in using TALENs and CRISPR-Cas9 with the PITCh systems
by Sakuma, Tetsushi and Sakuma, Tetsushi and Nakade, Shota and Nakade, Shota and Sakane, Yuto and Sakane, Yuto and Suzuki, Ken-Ichi T and Suzuki, Ken-Ichi T and Yamamoto, Takashi and Yamamoto, Takashi
Nature protocols, ISSN 1754-2189, 01/2016, Volume 11, Issue 1, pp. 118 - 133
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Cell Line | Animals | DNA Restriction Enzymes - metabolism | Chromosomes - genetics | DNA End-Joining Repair - genetics | Humans | CRISPR-Cas Systems - genetics | Gene Knock-In Techniques - methods | Sequence Homology, Nucleic Acid | Genetic engineering | Genetic vectors | Properties | Methods | Genetic screening | Innovations | Index Medicus
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5. Full Text Nuclease‐mediated genome editing: At the front‐line of functional genomics technology
by Sakuma, Tetsushi and Woltjen, Knut
Development, growth & differentiation, ISSN 0012-1592, 01/2014, Volume 56, Issue 1, pp. 2 - 13
clustered regularly interspaced short palindromic repeats | genome editing | transcription activator‐like effector nucleases | zinc‐finger nucleases | Transcription activator-like effector nucleases | Genome editing | Clustered regularly interspaced short palindromic repeats | Zinc-finger nucleases | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Genetic Engineering - methods | Animals | Humans | CRISPR-Cas Systems | Developmental Biology - methods | Endodeoxyribonucleases - metabolism | Genome - genetics | Genomics - methods | Genetic research | Genomics | Genomes | DNA repair | DNA damage | Deoxyribonucleic acid--DNA | Index Medicus
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6. Full Text Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells
by Ochiai, Hiroshi and Sugawara, Takeshi and Sakuma, Tetsushi and Yamamoto, Takashi
Scientific reports, ISSN 2045-2322, 2014, Volume 4, Issue 1, pp. 7125 - 7125
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Line | Embryonic Stem Cells - metabolism | Promoter Regions, Genetic | Embryonic Stem Cells - cytology | Nanog Homeobox Protein | Signal Transduction | Homeodomain Proteins - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Molecular Sequence Data | In Situ Hybridization, Fluorescence | Mice, Transgenic | Homeodomain Proteins - genetics | Genetic Variation | Animals | Stochastic Processes | Base Sequence | Transcription, Genetic | Cell Differentiation | Mice | Primary Cell Culture | Cell fate | Noise | Transcription activation | Stem cells | Embryo cells | Fluorescence in situ hybridization | Stem cell transplantation | Stochasticity | Gene expression | Embryos | Pluripotency | Index Medicus
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7. Full Text Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9
by Nakade, Shota and Tsubota, Takuya and Sakane, Yuto and Kume, Satoshi and Sakamoto, Naoaki and Obara, Masanobu and Daimon, Takaaki and Sezutsu, Hideki and Yamamoto, Takashi and Sakuma, Tetsushi and Suzuki, Ken-Ichi T
Nature communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5560 - 5560
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Xenopus | Humans | Molecular Sequence Data | Homologous Recombination | DNA - metabolism | Deoxyribonucleases | Bombyx | Animals | Genetic Engineering | Plasmids | Base Sequence | CRISPR-Cas Systems | Genetic Vectors | Gene Knock-In Techniques - methods | Saccharomyces cerevisiae | Index Medicus
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8. Full Text Magic wands of CRISPR—lots of choices for gene knock-in
by Sakuma, Tetsushi and Yamamoto, Takashi
Cell biology and toxicology, ISSN 0742-2091, 12/2017, Volume 33, Issue 6, pp. 501 - 505
Life Sciences | Biochemistry, general | Pharmacology/Toxicology | Cell Biology | Toxicology | Life Sciences & Biomedicine | Science & Technology | Animals | Animals, Genetically Modified - genetics | Gene Expression - genetics | DNA | Humans | Clustered Regularly Interspaced Short Palindromic Repeats | Gene Knock-In Techniques | Genetic research | CRISPR | Genomics | Index Medicus
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