X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (13) 13
index medicus (9) 9
animals (8) 8
cancer (7) 7
mice (7) 7
oncology (6) 6
iron (5) 5
tumors (5) 5
cell line, tumor (4) 4
expression (4) 4
genetics (4) 4
lung-cancer (4) 4
mice, knockout (4) 4
neoplasms (4) 4
neuroblastoma (4) 4
antitumor-activity (3) 3
cell proliferation - drug effects (3) 3
depletion (3) 3
dna (3) 3
dna repair (3) 3
effective antiproliferative agents (3) 3
gene expression (3) 3
genetic aspects (3) 3
mutation (3) 3
proteins (3) 3
research (3) 3
review (3) 3
article (2) 2
ataxia (2) 2
biochemistry & molecular biology (2) 2
biomarkers (2) 2
bladder-cancer (2) 2
breast-cancer (2) 2
cancer-cells (2) 2
cell biology (2) 2
cell cycle (2) 2
cell cycle proteins - genetics (2) 2
cell cycle proteins - metabolism (2) 2
chemotherapy (2) 2
childhood cancer (2) 2
colorectal-cancer (2) 2
copper (2) 2
deoxyribonucleic acid (2) 2
diet (2) 2
disease models, animal (2) 2
dna repair - genetics (2) 2
dna-binding proteins - genetics (2) 2
gene expression regulation - drug effects (2) 2
genetic instability (2) 2
genetic predisposition to disease (2) 2
growth (2) 2
health aspects (2) 2
hypoxia (2) 2
in-situ hybridization (2) 2
iron - metabolism (2) 2
medicine (2) 2
medicine, research & experimental (2) 2
meta-analysis (2) 2
metaanalysis (2) 2
metabolism (2) 2
molecular biology (2) 2
molecular imaging (2) 2
molecular targets (2) 2
mrna (2) 2
multidisciplinary sciences (2) 2
myc protein (2) 2
neoplasms - genetics (2) 2
neuroblastoma - drug therapy (2) 2
nuclear proteins - metabolism (2) 2
p53 (2) 2
pyridoxal isonicotinoyl hydrazone (2) 2
review article (2) 2
risk (2) 2
risk factors (2) 2
rna (2) 2
rodents (2) 2
saccharomyces-cerevisiae (2) 2
science (2) 2
signal transduction - drug effects (2) 2
translation (2) 2
transporter (2) 2
tumor cells, cultured (2) 2
40s ribosomal-subunits (1) 1
abcc4 (1) 1
activation (1) 1
adaptor proteins, signal transducing - metabolism (1) 1
adenosine triphosphate (1) 1
adolescents (1) 1
adult (1) 1
advances (1) 1
alk, anaplastic lymphoma kinase (1) 1
all, acute lymphoblastic leukemia (1) 1
aminobiphenyl compounds - toxicity (1) 1
aml, acute myeloid leukemia (1) 1
amyloid precursor protein (1) 1
analysis (1) 1
anthropology (1) 1
anticancer drugs (1) 1
antimitotic agents (1) 1
antineoplastic agents (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e57273
Iron is critical for cellular proliferation and its depletion leads to a suppression of both DNA synthesis and global translation. These observations suggest... 
MOLECULAR TARGETS | POSTTRANSCRIPTIONAL REGULATION | RIBONUCLEOTIDE REDUCTASE | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | MULTIDISCIPLINARY SCIENCES | EFFECTIVE ANTIPROLIFERATIVE AGENTS | PYRIDOXAL ISONICOTINOYL HYDRAZONE | CYCLE PROGRESSION | SACCHAROMYCES-CEREVISIAE | GROWTH SUPPRESSION | METASTASIS SUPPRESSOR GENE | Humans | Intracellular Signaling Peptides and Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p27 - antagonists & inhibitors | Cell Cycle Proteins - antagonists & inhibitors | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | RNA, Messenger - biosynthesis | Cytoplasmic Granules - metabolism | Iron - deficiency | Cell Cycle Proteins - genetics | Eukaryotic Initiation Factor-3 - genetics | Stress, Physiological - drug effects | Iron - pharmacology | Intracellular Signaling Peptides and Proteins - genetics | Fibroblasts - metabolism | Stress, Physiological - genetics | Cytoplasmic Granules - drug effects | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Eukaryotic Initiation Factor-3 - metabolism | Gene Expression Regulation - drug effects | Eukaryotic Initiation Factor-3 - antagonists & inhibitors | Animals | Signal Transduction - drug effects | Tunicamycin - pharmacology | Fibroblasts - drug effects | Cytoplasmic Granules - genetics | Cell Line, Tumor | Protein Biosynthesis - drug effects | Cell Proliferation - drug effects | Fibroblasts - cytology | Mice | Cell Hypoxia - genetics | Cyclin-Dependent Kinase Inhibitor p27 - genetics | Proteins | DNA synthesis | RNA | Genetic translation | Tunicamycin | Iron | Identification | mRNA | Metastasis | Myc protein | Kinases | Metastases | Recruitment | Cyclin-dependent kinase | Ribonucleotide reductase | Rodents | Cell cycle | Stress response | Inducers | Deoxyribonucleic acid--DNA | Stresses | Translation | Translation initiation | Pharmacology | Gene expression | DNA biosynthesis | Pathology | Hypotheses | Depletion | Granular materials | Medical prognosis | Cyclin-dependent kinase inhibitor p27 | Hypoxia | Granules | Cellular stress response | Cancer | Tumors | Deoxyribonucleic acid | DNA
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2012, Volume 109, Issue 50, pp. 20590 - 20595
There is no effective treatment for the cardiomyopathy of the most common autosomal recessive ataxia, Friedreich ataxia (FA). This disease is due to decreased... 
Heart | Protein metabolism | Energy metabolism | Diet | Liver | Cardiomyopathies | Mice | Down regulation | Ferritins | Skeletal muscle | Ferroportin 1 | Hemojuvelin | Transferrin receptor 1 | Heme oxygenase | heme oxygenase | MECHANISM | HEME-SYNTHESIS | MULTIDISCIPLINARY SCIENCES | CARDIOMYOPATHY | TRAFFICKING | hemojuvelin | RETICULOCYTES | ferroportin 1 | SUCCINYLACETONE | METABOLISM | transferrin receptor 1 | TISSUES | FERRITIN | PROTEINS | Mitochondria, Heart - metabolism | Creatine Kinase, MM Form - metabolism | Friedreich Ataxia - pathology | Humans | Cardiomegaly - pathology | Iron, Dietary - administration & dosage | Iron-Binding Proteins - metabolism | Friedreich Ataxia - genetics | Mice, Mutant Strains | Myocardium - metabolism | Disease Models, Animal | Iron - blood | Myocardium - ultrastructure | Microscopy, Electron, Transmission | Friedreich Ataxia - metabolism | Creatine Kinase, MM Form - genetics | Signal Transduction | Spectroscopy, Mossbauer | Liver - metabolism | Iron - metabolism | Mice, Knockout | Animals | Cardiomegaly - prevention & control | Iron-Binding Proteins - antagonists & inhibitors | Iron-Binding Proteins - genetics | Iron Regulatory Protein 2 - metabolism | Cardiomegaly - metabolism | Physiological aspects | Ataxia | Development and progression | Iron in the body | Metabolism | Health aspects | Phosphotransferases | Biological Sciences
Journal Article
BBA - Reviews on Cancer, ISSN 0304-419X, 2010, Volume 1806, Issue 2, pp. 275 - 286
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2016, Volume 22, Issue 1 Supplement, pp. 51 - 51
Journal Article
Science Translational Medicine, ISSN 1946-6234, 11/2015, Volume 7, Issue 312, pp. 312ra176 - 312ra176
Journal Article
Mutagenesis, ISSN 0267-8357, 11/2007, Volume 22, Issue 6, pp. 381 - 385
Journal Article
Theranostics, ISSN 1838-7640, 2018, Volume 8, Issue 20, pp. 5645 - 5659
Given the strong clinical evidence that copper levels are significantly elevated in a wide spectrum of tumors, copper homeostasis is considered as an emerging... 
Molecular imaging | Anticancer drugs | Neuroblastoma | Copper | PET | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | TRANSPORTER | PHASE-II | DEPLETION | RISK | TETRATHIOMOLYBDATE | BREAST-CANCER | GLUTATHIONE | MOUSE MODEL
Journal Article
European Journal of Cancer, ISSN 0959-8049, 09/2017, Volume 83, pp. 132 - 141
Journal Article