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Angewandte Chemie International Edition, ISSN 1433-7851, 12/2017, Volume 56, Issue 49, pp. 15612 - 15616
We report the discovery of a new bioorthogonal click‐and‐release reaction involving iminosydnones and strained alkynes. This transformation leads to two... 
click chemistry | mesoionic compounds | bioorthogonal reactions | chemical biology | cleavage reactions | LIGATION | DRUG-RELEASE | CLEAVAGE | CHEMISTRY, MULTIDISCIPLINARY | CYCLOADDITION | CONJUGATION | PEPTIDES | CHEMICAL PROTEOMICS | CHEMISTRY | PROTEINS | Proteins | Drug delivery systems | Transformation | Fishing | Design modifications | Alkynes
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 04/2019, Volume 55, Issue 31, pp. 4582 - 4585
We report the synthesis and use of sydnone-based profluorophores as tools for imaging applications. These new probes display exquisite reactivity towards... 
CHEMISTRY | CHEMISTRY, MULTIDISCIPLINARY | TETRAZINE PROBES
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 07/2015, Volume 56, Issue 31, pp. 4627 - 4630
The synthesis of multi-ynamides according to the copper-catalyzed Evano’s and Hsung’s methods is described. In these new compounds, the ynamide functions are... 
Ynamide | Biphenyl | Thiophene | Triphenylamine | Copper-catalysis | FORMAMIDES | N-FUNCTIONALIZED 1-ALKYNYLAMIDES | OXIDATIVE AMIDATION | EFFICIENT SYNTHESIS | 1,1-DIBROMO-1-ALKENES | CHEMISTRY, ORGANIC | TERMINAL ALKYNES | ALKYNYLATION | GENERAL-METHOD | CYCLOADDITIONS | DERIVATIVES | Organic chemistry | Material chemistry | Chemical Sciences
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 76, pp. 10758 - 10761
Copper-catalyzed and copper-free sydnone-alkyne cycloaddition reactions have emerged as complementary click tools for chemical biology but their use in... 
CHEMISTRY | CYCLOADDITION | CHEMISTRY, MULTIDISCIPLINARY | PROBES | Analytical chemistry | Life Sciences | Organic chemistry | Biomolecules | Biochemistry, Molecular Biology | Chemical Sciences
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 07/2017, Volume 53, Issue 56, pp. 7890 - 7893
A convenient and effective synthetic access to chelating azides was designed enabling the preparation of efficient clickable fluorescent derivatives. The... 
CONJUGATION | ALKYNE CYCLOADDITIONS | BIOCONJUGATION | CUAAC | CHEMISTRY | LIGATION | TERMINAL ALKYNES | BIOMOLECULES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
ISSN 1359-7345, 7/2017, Volume 53, Issue 56, pp. 789 - 7893
A convenient and effective synthetic access to chelating azides was designed enabling the preparation of efficient clickable fluorescent derivatives. The... 
Journal Article
ACS CATALYSIS, ISSN 2155-5435, 07/2019, Volume 9, Issue 7, pp. 5897 - 5901
An integrated catalytic decarboxylation/carboxylation for accessing isotopically labeled carboxylic acids with (CO2)-C-13 or (CO2)-C-14 is described. The... 
nickel | carbon dioxide | carboxylic acid | CHEMISTRY, PHYSICAL | C-H FUNCTIONALIZATION | DISCOVERY | C-14 | isotopic labeling | RADIOLABELED COMPOUNDS | ARYL HALIDES | carboxylation | REMOTE | TRITIUM | DECARBOXYLATIVE CYANATION | DRUG-METABOLISM
Journal Article
Chemical Communications, ISSN 1359-7345, 12/2012, Volume 48, Issue 100, pp. 12165 - 12167
Journal Article
ISSN 1359-7345, 4/2019, Volume 55, Issue 31, pp. 4582 - 4585
We report the synthesis and use of sydnone-based profluorophores as tools for imaging applications. These new probes display exquisite reactivity towards... 
Journal Article
Chemical Communications : Chem Comm, ISSN 1359-7345, 01/2019, Volume 55, Issue 31, pp. 4582 - 4585
We report the synthesis and use of sydnone-based profluorophores as tools for imaging applications. These new probes display exquisite reactivity towards... 
Proteins | Cycloaddition | Labelling
Journal Article
ISSN 1359-7345, 9/2018, Volume 54, Issue 76, pp. 1758 - 1761
Copper-catalyzed and copper-free sydnone-alkyne cycloaddition reactions have emerged as complementary click tools for chemical biology but their use in... 
Journal Article
Chemical Communications : Chem Comm, ISSN 1359-7345, 01/2018, Volume 54, Issue 76, pp. 10758 - 10761
Copper-catalyzed and copper-free sydnone–alkyne cycloaddition reactions have emerged as complementary click tools for chemical biology but their use in... 
Proteins | Organic chemistry | Cycloaddition | Fluorescence | Labelling | Chemical reactions | Copper | Coumarin | Pyrazole | Alkynes
Journal Article
Organometallics, ISSN 0276-7333, 10/2011, Volume 30, Issue 19, pp. 5284 - 5290
Four organometallic nucleobases have been prepared and characterized, each consisting of a disubstituted ferrocene unit connected through either a conjugated... 
SUPRAMOLECULAR PACKING | DNA | CHEMISTRY, ORGANIC | CRYSTAL-STRUCTURES | REDOX PROPERTIES | BASE | CHEMISTRY, INORGANIC & NUCLEAR
Journal Article
Tetrahedron, ISSN 0040-4020, 06/2012, Volume 68, Issue 24, pp. 4655 - 4663
In continuance of our search for newer anti-cancer agents we were interested on embelin, a XIAP (X-linked inhibitor of apoptosis protein) inhibitor. This... 
Embelin | Benzoquinone | Hydrophilic analogues | CHEMISTRY, ORGANIC | LINKED INHIBITOR | PRODUCTS | Derivatives (Financial instruments) | Heterocyclic compounds | Analysis | Quinone | Biotechnology | Inhibitors | Synthesis | Chains | Derivatives | Carbon | Flexibility | Organic chemistry | Chemical Sciences
Journal Article
2014
Bioorganometallic chemistry is a growing field of research in which organometallic chemistry is combined with biology to achieve novel molecules with novel... 
QD Chemistry
Dissertation
Angewandte Chemie, ISSN 0044-8249, 12/2017, Volume 129, Issue 49, pp. 15818 - 15822
We report the discovery of a new bioorthogonal click‐and‐release reaction involving iminosydnones and strained alkynes. This transformation leads to two... 
Spaltungsreaktionen | Bioorthogonale Reaktionen | Chemische Biologie | Mesoionische Verbindungen | Klick-Chemie | Proteins | Drug delivery systems | Transformation | Fishing | Design modifications | Alkynes
Journal Article
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