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JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 12, pp. 1536 - 1544
Abstract Background The long-term effect of thrombolytic treatment of pulmonary embolism (PE) is unknown. Objectives This study investigated the long-term... 
Cardiovascular | Internal Medicine | chronic thromboembolic pulmonary hypertension | thrombolysis | long-term survival | pulmonary embolism | prognosis | DIAGNOSIS | CARDIAC & CARDIOVASCULAR SYSTEMS | MANAGEMENT | GUIDELINES | CARDIOLOGY ESC | EUROPEAN-SOCIETY | TIME TRENDS | TRIAL | TASK-FORCE | HYPERTENSION | Pulmonary Embolism - prevention & control | Echocardiography | Double-Blind Method | Humans | Middle Aged | Male | Treatment Outcome | Tissue Plasminogen Activator - therapeutic use | Pulmonary Embolism - mortality | Fibrinolytic Agents - therapeutic use | Thrombolytic Therapy | Aged, 80 and over | Female | Aged | Tenecteplase | Pulmonary Embolism - diagnostic imaging | Pulmonary embolism | Stroke (Disease) | Medicine, Experimental | Medical research | Cardiology | Cardiovascular agents | Heart | Therapy | Chest | Incidence | Design | Computed tomography | Motivation | Tomography | Diagnosis | Thromboembolism | Anticoagulants | Pulmonary arteries | Mortality | Statistical tests | Patients | Fibrinolysis | Survival | Computation | Diagnostic software | Death | Health risk assessment | Risk management | Angiography | Arches | Embolisms | Medical services | Clinical trials | Population studies | Hemorrhage | Bleeding | Guidelines | Reperfusion | Risk assessment | Calcium-binding protein | Trends | Heart diseases | Injuries | Hypertension | Collapse | Stroke | Statistical analysis | Receiving | Steering | Complications | Risk reduction | Statistics | Pulmonary hypertension | Embolism | Computer programs | Contact | Thromboplastin | Medical prognosis | Fatalities | Ventricle | Heparin | Life Sciences | Human health and pathology | Cardiology and cardiovascular system
Journal Article
Chest, ISSN 0012-3692, 2012, Volume 142, Issue 6, pp. 1417 - 1424
Background In patients with acute pulmonary embolism (PE), the correlation between the embolic burden assessed by multidetector CT (MDCT) scan and clinical... 
Pulmonary/Respiratory
Journal Article
by Majounie, Elisa, PhD and Renton, Alan E, PhD and Mok, Kin, MSc and Dopper, Elise GP and Waite, Adrian, PhD and Rollinson, Sara, PhD and Chiò, Adriano, MD and Restagno, Gabriella, MD and Nicolaou, Nayia, MSc and Simon-Sanchez, Javier, PhD and van Swieten, John C, Prof and Abramzon, Yevgeniya and Johnson, Janel O, PhD and Sendtner, Michael, Prof and Pamphlett, Roger, MD and Orrell, Richard W, MD and Mead, Simon, MD and Sidle, Katie C, MD and Houlden, Henry, Prof and Rohrer, Jonathan D, MD and Morrison, Karen E, Prof and Pall, Hardev, MD and Talbot, Kevin, Prof and Ansorge, Olaf, MD and Hernandez, Dena G, MSc and Arepalli, Sampath, MS and Sabatelli, Mario, MD and Mora, Gabriele, MD and Corbo, Massimo, MD and Giannini, Fabio, MD and Calvo, Andrea, MD and Englund, Elisabet, MD and Borghero, Giuseppe, MD and Floris, Gian Luca, MD and Remes, Anne M, Prof and Laaksovirta, Hannu, MD and McCluskey, Leo, MD and Trojanowski, John Q, Prof and Van Deerlin, Vivianna M, MD and Schellenberg, Gerard D, Prof and Nalls, Michael A, PhD and Drory, Vivian E, MD and Lu, Chin-Song, Prof and Yeh, Tu-Hsueh, MD and Ishiura, Hiroyuki, MD and Takahashi, Yuji, MD and Tsuji, Shoji, Prof and Le Ber, Isabelle, MD and Brice, Alexis, Prof and Drepper, Carsten, PhD and Williams, Nigel, PhD and Kirby, Janine, PhD and Shaw, Pamela, Prof and Hardy, John, Prof and Tienari, Pentti J, MD and Heutink, Peter, Prof and Morris, Huw R, MD and Pickering-Brown, Stuart, Prof and Traynor, Bryan J, Dr and Chromosome 9-ALS FTD Consortium and French Res Network FTLD FTLD ALS and ITALSGEN Consortium and French research network on FTLD/FTLD/ALS and Chromosome 9-ALS/FTD Consortium and Oncology and Pathology, Kamprad Lab and Lund University and Lunds universitet and Onkologi och Patologi, Kampradlab
Lancet Neurology, The, ISSN 1474-4422, 2012, Volume 11, Issue 4, pp. 323 - 330
Summary Background We aimed to accurately estimate the frequency of a hexanucleotide repeat expansion in C9orf72 that has been associated with a large... 
Neurology | PREVALENCE | MUTATIONS | LOBAR DEGENERATION | GENETICS | TDP-43 | CLINICAL NEUROLOGY | Frontotemporal Dementia - genetics | Cross-Sectional Studies | DNA Repeat Expansion - genetics | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | Child, Preschool | Genotype | Male | Genetic Loci | Open Reading Frames - genetics | Young Adult | Chromosomes, Human, Pair 9 - genetics | Adolescent | Age of Onset | Aged, 80 and over | Adult | Female | Aged | Child | Cohort Studies | Medical research | Medical colleges | Care and treatment | Nervous system diseases | Neurosciences | Molecular genetics | Oncology, Experimental | Questions and answers | Amyotrophic lateral sclerosis | Research | Medicine, Experimental | Agriculture | Physicians (General practice) | Alzheimer's disease | Dementia | Cancer | Biomedical engineering | Haplotypes | Polymerase chain reaction | Neurodegenerative diseases | Ethnic groups | Data processing | Mutation | Frontotemporal dementia | Genetic counselling | Islands | Age | Toll-Like Receptor 4 | Open Reading Frames | Adaptor Proteins, Vesicular Transport | Lipopolysaccharides | Life Sciences | DNA Repeat Expansion | Interferon Regulatory Factor-3 | Transfection | Amyotrophic Lateral Sclerosis | RNA Interference | HEK293 Cells | Membrane Glycoproteins | Vesicular Transport Proteins | Protein Structure, Tertiary | Cell Line | Chemokine CCL5 | Frontotemporal Dementia | Signal Transduction | Myeloid Differentiation Factor 88 | Chromosomes, Human, Pair 9 | Protein Transport | Adaptor Proteins, Signal Transducing | Santé publique et épidémiologie | RNA, Small Interfering | Endosomes | Neurologi | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article
by Okbay, Aysu and Beauchamp, Jonathan and Fontana, M.A and Lee, James J and Pers, Tune and Rietveld, C.A and Turley, Patrick and Chen, G.-B and Emilsson, Valur and Meddens, S.F.W and Oskarsson, S and Pickrell, J.K and Thom, K and Timshel, P and Vlaming, Ronald and Abdellaoui, Abdel and Ahluwalia, Tarunveer Singh and Bacelis, Jonas and Baumbach, Clemens and Bjornsdottir, G and Brandsma, Johan and Pina Concas, M and Derringer, J and Furlotte, N.A and Galesloot, Tessel and Girotto, S and Gupta, R and Hall, Leanne M and Harris, Sarah and Hofer, E and Horikoshi, M and Huffman, Jennifer E and Kaasik, K and Kalafati, Ioanna-Panagiota and Karlsson, Robert and Kong, Augustine and Lahti, Jari and Lee, Sven and Deleeuw, C and Lind, Penelope and Lindgren, K.-O and Liu, T and Mangino, Massimo and Marten, Jonathan and Mihailov, Evelin and Miller, Mike and Most, Peter and Oldmeadow, Christopher and Payton, Antony and Pervjakova, Natalia and Peyrot, Wouter and Qian, Y and Raitakari, Olli and Rueedi, R and Salvi, E and Schmidt, B and Schraut, K.E and Shi, J and Smith, Albert Vernon and Poot, Raymond and St Pourcain, Beate and Teumer, Alexander and Thorleifsson, Gudmar and Verweij, Niek and Vuckovic, gana and Wellmann, J and Westra, Harm-Jan and Yang, J and Zhao, W and Zhu, Z and Alizadeh, Behrooz and Amin, Najaf and Bakshi, A and Baumeister, Sebastian and Biino, G and Bønnelykke, Klaus and Boyle, Patricia and Campbell, Harry and Cappuccio, F.P and Davies, Gail and Neve, Jan-Emmanuel and Deloukas, Panagiotis and Demuth, Ilja and Ding, J and Eibich, P and Eisele, L and Eklund, Niina and Evans, David and Faul, Jessica D and Feitosa, Mary Furlan and Forstner, Aneas and Gandin, Ilaria and Gunnarsson, B and Halldorsson, Bjarni and Harris, Tamara and Holliday, Elizabeth and Heath, Anew C and Hocking, L.J and Homuth, Georg and Horan, Mike and ... and LifeLines Cohort Study and Humanistisk-samhällsvetenskapliga vetenskapsområdet and Uppsala universitet and Statsvetenskapliga institutionen and Samhällsvetenskapliga fakulteten
Nature: international weekly journal of science, ISSN 0028-0836, 05/2016, Volume 533, Issue 7604, pp. 539 - 542
Journal Article
by Lee, James J and Wedow, Robbee and Okbay, Aysu and Kong, Edward and Maghzian, Omeed and Zacher, Meghan and Nguyen-Viet, Tuan Anh and Bowers, Peter and Sidorenko, Julia and Karlsson Linnér, Richard and Fontana, Mark Alan and Kundu, Tushar and Lee, Chanwook and Li, Hui and Li, Ruoxi and Royer, Rebecca and Timshel, Pascal N and Walters, Raymond K and Willoughby, Emily A and Yengo, Loïc and Agee, Michelle and Alipanahi, Babak and Auton, Adam and Bell, Robert K and Bryc, Katarzyna and Elson, Sarah L and Fontanillas, Pierre and Hinds, David A and McCreight, Jennifer C and Huber, Karen E and Litterman, Nadia K and McIntyre, Matthew H and Mountain, Joanna L and Noblin, Elizabeth S and Northover, Carrie A. M and Pitts, Steven J and Sathirapongsasuti, J. Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tian, Chao and Vacic, Vladimir and Wilson, Catherine H and Okbay, Aysu and Beauchamp, Jonathan P and Fontana, Mark Alan and Lee, James J and Pers, Tune H and Rietveld, Cornelius A and Turley, Patrick and Chen, Guo-Bo and Emilsson, Valur and Meddens, S. Fleur W and Oskarsson, Sven and Pickrell, Joseph K and Thom, Kevin and Timshel, Pascal and Vlaming, Ronald de and Abdellaoui, Abdel and Ahluwalia, Tarunveer S and Bacelis, Jonas and Baumbach, Clemens and Bjornsdottir, Gyda and Brandsma, Johannes H and Concas, Maria Pina and Derringer, Jaime and Furlotte, Nicholas A and Galesloot, Tessel E and Girotto, Giorgia and Gupta, Richa and Hall, Leanne M and Harris, Sarah E and Hofer, Edith and Horikoshi, Momoko and Huffman, Jennifer E and Kaasik, Kadri and Kalafati, Ioanna P and Karlsson, Robert and Kong, Augustine and Lahti, Jari and van der Lee, Sven J and Leeuw, Christiaan de and Lind, Penelope A and Lindgren, Karl-Oskar and Liu, Tian and Mangino, Massimo and Marten, Jonathan and Mihailov, Evelin and Miller, Michael B and van der Most, Peter J and Oldmeadow, Christopher and Payton, Antony and Pervjakova, Natalia and Peyrot, Wouter J and Qian, Yong and Raitakari, Olli and Rueedi, Rico and Salvi, Erika and Schmidt, Börge and Schraut, Katharina E and ... and 23Me Res Team and Social Sci Genetic Assoc Consortiu and COGENT Cognitive Genomics Consorti and 23andMe Research Team and COGENT (Cognitive Genomics Consortium) and Social Science Genetic Association Consortium and Humanistisk-samhällsvetenskapliga vetenskapsområdet and Uppsala universitet and Statsvetenskapliga institutionen and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 08/2018, Volume 50, Issue 8, pp. 1112 - 1121
Journal Article
by Karlsson Linnér, Richard and Biroli, Pietro and Kong, Edward and Meddens, S. Fleur W and Wedow, Robbee and Fontana, Mark Alan and Lebreton, Maël and Tino, Stephen P and Abdellaoui, Abdel and Hammerschlag, Anke R and Nivard, Michel G and Okbay, Aysu and Rietveld, Cornelius A and Timshel, Pascal N and Trzaskowski, Maciej and Vlaming, Ronald de and Zünd, Christian L and Bao, Yanchun and Buzdugan, Laura and Caplin, Ann H and Chen, Chia-Yen and Eibich, Peter and Fontanillas, Pierre and Gonzalez, Juan R and Joshi, Peter K and Karhunen, Ville and Kleinman, Aaron and Levin, Remy Z and Lill, Christina M and Meddens, Gerardus A and Muntané, Gerard and Sanchez-Roige, Sandra and Rooij, Frank J. van and Taskesen, Erdogan and Wu, Yang and Zhang, Futao and Agee, Michelle and Alipanahi, Babak and Bell, Robert K and Bryc, Katarzyna and Elson, Sarah L and Furlotte, Nicholas A and Huber, Karen E and Litterman, Nadia K and McCreight, Jennifer C and McIntyre, Matthew H and Mountain, Joanna L and Northover, Carrie A. M and Pitts, Steven J and Sathirapongsasuti, J. Fah and Sazonova, Olga V and Shelton, Janie F and Shringarpure, Suyash and Tian, Chao and Tung, Joyce Y and Vacic, Vladimir and Wilson, Catherine H and Agbessi, Mawussé and Ahsan, Habibul and Alves, Isabel and Andiappan, Anand and Awadalla, Philip and Battle, Alexis and Beutner, Frank and Jan Bonder, Marc and Boomsma, Dorret I and Christiansen, Mark and Claringbould, Annique and Deelen, Patrick and Esko, Tõnu and Favé, Marie-Julie and Franke, Lude and Frayling, Timothy and Gharib, Sina A and Gibson, Gregory and Heijmans, Bastiaan and Hemani, Gibran and Jansen, Rick and Kähönen, Mika and Kalnapenkis, Anette and Kasela, Silva and Kettunen, Johannes and Kim, Yungil and Kirsten, Holger and Kovacs, Peter and Krohn, Knut and Kronberg-Guzman, Jaanika and Kukushkina, Viktorija and Kutalik, Zoltan and Lee, Bernett and Lehtimäki, Terho and Loeffler, Markus and Marigorta, Urko M and Metspalu, Andres and Milani, Lili and Montgomery, Grant W and Müller-Nurasyid, Martina and Nauck, Matthias and Nivard, Michel G and Penninx, Brenda and ... and eQTLgen Consortium and 23and Me Res Team and Soc Sci Genetic Association Con and Int Cannabis Consortium and 23and Me Research Team and International Cannabis Consortium and Social Science Genetic Association Consortium
Nature Genetics, ISSN 1061-4036, 02/2019, Volume 51, Issue 2, pp. 245 - 257
Journal Article
Journal Article
by Johnson, Janel O and Pioro, Erik P and Boehringer, Ashley and Chia, Ruth and Feit, Howard and Renton, Alan E and Pliner, Hannah A and Abramzon, Yevgeniya and Marangi, Giuseppe and Winborn, Brett J and Gibbs, J. Raphael and Nalls, Michael A and Morgan, Sarah and Shoai, Maryam and Hardy, John and Pittman, Alan and Orrell, Richard W and Malaspina, Andrea and Sidle, Katie C and Fratta, Pietro and Harms, Matthew B and Baloh, Robert H and Pestronk, Alan and Weihl, Conrad C and Rogaeva, Ekaterina and Zinman, Lorne and Drory, Vivian E and Borghero, Giuseppe and Mora, Gabriele and Calvo, Andrea and Rothstein, Jeffrey D and Drepper, Carsten and Sendtner, Michael and Singleton, Andrew B and Taylor, J Paul and Cookson, Mark R and Restagno, Gabriella and Sabatelli, Mario and Bowser, Robert and Chio`, Adriano and Traynor, Bryan J and Moglia, Cristina and Cammarosano, Stefania and Canosa, Antonio and Gallo, Sara and Brunetti, Maura and Ossola, Irene and Marinou, Kalliopi and Papetti, Laura and Pisano, Fabrizio and Pinter, Giuseppe Lauria and Conte, Amelia and Luigetti, Marco and Zollino, Marcella and Lattante, Serena and Marangi, Giuseppe and la Bella, Vincenzo and Spataro, Rossella and Colletti, Tiziana and Battistini, Stefania and Ricci, Claudia and Caponnetto, Claudia and Mancardi, Gianluigi and Mandich, Paola and Salvi, Fabrizio and Bartolomei, Ilaria and Mandrioli, Jessica and Sola, Patrizia and Lunetta, Christian and Penco, Silvana and Monsurrò, Maria Rosaria and Conforti, Francesca Luisa and Tedeschi, Gioacchino and Gambardella, Antonio and Quattrone, Aldo and Volanti, Paolo and Floris, Gianluca and Cannas, Antonino and Piras, Valeria and Marrosu, Francesco and Marrosu, Maria Giovanna and Murru, Maria Rita and Pugliatti, Maura and Parish, Leslie D and Sotgiu, Alessandra and Solinas, Giuliana and Ulgheri, Lucia and Ticca, Anna and Simone, Isabella and Logroscino, Giancarlo and Pirisi, Angelo and ITALSGEN
Nature Neuroscience, ISSN 1097-6256, 2014, Volume 17, Issue 5, pp. 664 - 666
Journal Article