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index medicus (23) 23
humans (21) 21
animals (17) 17
male (11) 11
oxidative stress (11) 11
quercetin (11) 11
flavonoids (10) 10
inflammation (10) 10
lycopersicon esculentum - virology (8) 8
non-alcoholic fatty liver disease (8) 8
quercetin - pharmacology (8) 8
gastroenterology & hepatology (7) 7
gene-expression (7) 7
medicine, research & experimental (7) 7
plant diseases - virology (7) 7
rats (7) 7
begomovirus (6) 6
cells, cultured (6) 6
food and beverages (6) 6
geminivirus (6) 6
intestinal microbiota (6) 6
liver (6) 6
physiological aspects (6) 6
tomato (6) 6
begomovirus - genetics (5) 5
disease models, animal (5) 5
fatty liver (5) 5
flavonoids - pharmacology (5) 5
gene expression (5) 5
hepatocytes - drug effects (5) 5
liver - metabolism (5) 5
liver - pathology (5) 5
nitric oxide (5) 5
nitric-oxide synthase (5) 5
pharmacology & pharmacy (5) 5
rats, wistar (5) 5
reactive oxygen species - metabolism (5) 5
recombination, genetic (5) 5
virology (5) 5
analysis (4) 4
biochemistry & molecular biology (4) 4
cell line (4) 4
down-regulation (4) 4
expression (4) 4
fatty liver - genetics (4) 4
fatty liver - metabolism (4) 4
food science & technology (4) 4
fungi (4) 4
geminiviruses (4) 4
gut-liver axis (4) 4
hepacivirus - physiology (4) 4
insulin-resistance (4) 4
kaempferols - pharmacology (4) 4
lipid-accumulation (4) 4
lipid-peroxidation (4) 4
medicine (4) 4
mice (4) 4
microbiota (4) 4
nf-kappa-b (4) 4
phylogeny (4) 4
recombination (4) 4
up-regulation (4) 4
adult (3) 3
alanine transaminase - blood (3) 3
article (3) 3
aspartate aminotransferases - blood (3) 3
begomovirus - isolation & purification (3) 3
begomovirus - physiology (3) 3
bilirubin - blood (3) 3
clinical trial (3) 3
complete nucleotide-sequence (3) 3
dna-replication (3) 3
dysbiosis (3) 3
epidemiology (3) 3
female (3) 3
geminiviridae - genetics (3) 3
genes (3) 3
genetic diversity (3) 3
glutathione - metabolism (3) 3
hcv replication (3) 3
helicobacter-pylori infection (3) 3
hemiptera - virology (3) 3
hepatic steatosis (3) 3
hepatitis c (3) 3
immunity (3) 3
insulin resistance (3) 3
lipid-metabolism (3) 3
lipids (3) 3
lipogenesis - genetics (3) 3
liver x receptors (3) 3
metabolic syndrome (3) 3
molecular sequence data (3) 3
nafld (3) 3
nf-kappa b - metabolism (3) 3
nitric oxide synthase - metabolism (3) 3
nitric oxide synthase type ii (3) 3
non-alcoholic fatty liver disease - drug therapy (3) 3
non-alcoholic fatty liver disease - metabolism (3) 3
nutrition & dietetics (3) 3
obesity (3) 3
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1. Full Text A novel strain of tomato leaf curl New Delhi virus has spread to the Mediterranean basin
by Fortes, Isabel M and Sánchez-Campos, Sonia and Fiallo-Olivé, Elvira and Díaz-Pendón, Juan A and Navas-Castillo, Jesús and Moriones, Enrique
Viruses, ISSN 1999-4915, 11/2016, Volume 8, Issue 11, p. 307
Tomato leaf curl New Delhi virus (ToLCNDV) is a whitefly-transmitted bipartite begomovirus (genus Begomovirus, family Geminiviridae) that causes damage to... 
Recombination | Genetic diversity | Cucurbits | Tomato leaf curl New Delhi virus | Begomovirus | Tomato | CASSAVA MOSAIC DISEASE | genetic diversity | recombination | 1ST REPORT | tomato | INFECTING CUCUMBER | DNA-B | cucurbits | GEMINIVIRUS | COAT PROTEIN | VIROLOGY | BEMISIA-TABACI | SARDINIA-VIRUS | Plant Diseases - virology | Begomovirus - classification | Begomovirus - genetics | Begomovirus - isolation & purification | Cucurbitaceae - virology | Recombination, Genetic | Phylogeny | Evolution, Molecular | Spain
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2. Full Text Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C
by Miquilena-Colina, María Eugenia and Lima-Cabello, Elena and Sánchez-Campos, Sonia and García-Mediavilla, María Victoria and Fernández-Bermejo, Miguel and Lozano-Rodríguez, Tamara and Vargas-Castrillón, Javier and Buqué, Xabier and Ochoa, Begoña and Aspichueta, Patricia and González-Gallego, Javier and García-Monzón, Carmelo
Gut, ISSN 0017-5749, 10/2011, Volume 60, Issue 10, pp. 1394 - 1402
BackgroundFatty acid translocase CD36 (FAT/CD36) mediates uptake and intracellular transport of long-chain fatty acids in diverse cell types. While the... 
SKELETAL-MUSCLE | METABOLIC SYNDROME | VIRUS-INFECTION | MEDICAL PROGRESS | LIPID-METABOLISM | CONJUGATED LINOLEIC-ACID | OBESE ZUCKER RATS | PPAR-GAMMA | HEPATOCYTE-DERIVED CELLS | LIVER-DISEASE | GASTROENTEROLOGY & HEPATOLOGY | Immunohistochemistry | Translocation, Genetic | Up-Regulation | Liver - pathology | CD36 Antigens - genetics | Liver - enzymology | Follow-Up Studies | Humans | Middle Aged | Fatty Liver - complications | Male | Hepatitis C, Chronic - complications | Young Adult | Hyperinsulinism - etiology | Hepatitis C, Chronic - enzymology | Fatty Liver - enzymology | Non-alcoholic Fatty Liver Disease | Polymerase Chain Reaction | Hyperinsulinism - enzymology | Hyperinsulinism - genetics | Adult | Female | Fatty Liver - genetics | Genetic Predisposition to Disease | RNA, Messenger - genetics | Genotype | Blotting, Western | Disease Progression | CD36 Antigens - biosynthesis | Insulin Resistance - genetics | Aged | Hepatitis C, Chronic - genetics | Enzymes | Liver diseases | Fatty acid metabolism | Liver | Causes of | Physiological aspects | Regulation | Research | Hepatitis C | Studies | Insulin resistance | Hyperglycemia | Rodents
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3. Full Text Intestinal microbiota modulation in obesity-related non-alcoholic fatty liver disease
by Porras, David and Nistal, Esther and Martínez-Flórez, Susana and González-Gallego, Javier and García-Mediavilla, María Victoria and Sánchez-Campos, Sonia
Frontiers in Physiology, ISSN 1664-042X, 2018, Volume 9, p. 1813
Obesity and associated comorbidities, including non-alcoholic fatty liver disease (NAFLD), are a major concern to public well-being worldwide due to their high... 
Physical exercise | Fecal microbiota transplantation (FMT) | Obesity | Probiotics | Intestinal microbiota | Non-alcoholic fatty liver disease (NAFLD) | Polyphenols | Prebiotics | non-alcoholic fatty liver disease (NAFLD) | polyphenols | METABOLIC SYNDROME | PHYSIOLOGY | LIPID-METABOLISM | INULIN-TYPE FRUCTANS | FECAL MICROBIOTA | DIET-INDUCED OBESITY | HIGH-INTENSITY INTERVAL | intestinal microbiota | ALLEVIATES HEPATIC STEATOSIS | ALTERS GUT MICROBIOTA | fecal microbiota transplantation (FMT) | DOUBLE-BLIND | prebiotics | ACTIVE ULCERATIVE-COLITIS | physical exercise | obesity | probiotics | Complications and side effects | Care and treatment | Fatty liver | Microbiota (Symbiotic organisms) | Research | Risk factors
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4. Full Text Emerging virus diseases transmitted by whiteflies
by Navas-Castillo, Jesús and Fiallo-Olivé, Elvira and Sánchez-Campos, Sonia
Annual Review of Phytopathology, ISSN 0066-4286, 09/2011, Volume 49, Issue 1, pp. 219 - 248
Virus diseases that have emerged in the past two decades limit the production of important vegetable crops in tropical, subtropical, and temperate regions... 
Ipomoviruses | Tomato | Bemisia tabaci | Torradoviruses | Begomoviruses | Criniviruses | criniviruses | BEMISIA-TABACI GENNADIUS | LEAF-CURL-VIRUS | TOMATO-TORRADO-VIRUS | CASSAVA MOSAIC GEMINIVIRUSES | VEIN-YELLOWING-VIRUS | INFECTIOUS-CHLOROSIS-VIRUS | torradoviruses | 1ST REPORT | tomato | COMPLETE NUCLEOTIDE-SEQUENCE | PLANT SCIENCES | ipomoviruses | PLANT-VIRUSES | begomoviruses | PICORNA-LIKE VIRUS | Virus Diseases - transmission | Hemiptera - physiology | Humans | Lycopersicon esculentum - virology | Plant Viruses - genetics | Virus Diseases - virology | Hemiptera - virology | Insect Vectors - virology | Geminiviridae - genetics | Animals | Insect Vectors - physiology | Plant Diseases - virology | Recombination, Genetic | Plant Viruses - classification | Mutation | Population Dynamics | Virus diseases | Aleyrodidae | Disease transmission | Agricultural pests
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5. Full Text Fruit polyphenols, immunity and inflammation
by González-Gallego, Javier and García-Mediavilla, M. Victoria and Sánchez-Campos, Sonia and Tuñón, María J
British Journal of Nutrition, ISSN 0007-1145, 10/2010, Volume 104, Issue S3, pp. S15 - S27
Flavonoids are a large class of naturally occurring compounds widely present in fruits, vegetables and beverages derived from plants. These molecules have been... 
Clinical trial | Flavonoids | Inflammation | Exercise | Epidemiology | Immunity | GREEN TEA POLYPHENOLS | DIETARY FLAVONOIDS | NITRIC-OXIDE SYNTHASE | BLOOD MONONUCLEAR-CELLS | DNA-BINDING ACTIVITY | ADHESION MOLECULE EXPRESSION | NUTRITION & DIETETICS | INDUCED OXIDATIVE STRESS | IN-VIVO | DOUBLE-BLIND | NF-KAPPA-B | Anti-Inflammatory Agents - pharmacology | Fruit - chemistry | Plant Extracts - pharmacology | Humans | Immunity - drug effects | Animals | Diet | Polyphenols | Flavonoids - pharmacology | Inflammation - prevention & control | Phytotherapy | Immunologic Factors - pharmacology | Tea - chemistry | Phenols - pharmacology | Nutrition research | Tea | Phytochemicals | Inflammatory diseases | Fruits | Immune system
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6. Full Text Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet‐induced mouse model of nonalcoholic fatty liver disease
by Pisonero‐Vaquero, Sandra and Martínez‐Ferreras, Ángel and García‐Mediavilla, María Victoria and Martínez‐Flórez, Susana and Fernández, Anna and Benet, Marta and Olcoz, José Luis and Jover, Ramiro and González‐Gallego, Javier and Sánchez‐Campos, Sonia
Molecular Nutrition & Food Research, ISSN 1613-4125, 05/2015, Volume 59, Issue 5, pp. 879 - 893
Scope Flavonoids and related compounds seem to have favorable effects on nonalcoholic fatty liver disease (NAFLD) progression, although the exact mechanisms... 
Fatty acid uptake | NAFLD | Lipid metabolism | Quercetin | PI3K/AKT pathway | BINDING-PROTEIN-ALPHA | SMALL HETERODIMER PARTNER | OXIDATIVE STRESS | PHOSPHATIDYLINOSITOL 3-KINASE | FOOD SCIENCE & TECHNOLOGY | DOWN-REGULATION | FACTOR-KAPPA-B | RECEPTOR-ALPHA | REACTIVE OXYGEN | HEPATIC STEATOSIS | HCV REPLICATION | Oxidative Stress | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Non-alcoholic Fatty Liver Disease - etiology | Male | Non-alcoholic Fatty Liver Disease - metabolism | Proto-Oncogene Proteins c-akt - physiology | Non-alcoholic Fatty Liver Disease - drug therapy | Gene Expression Regulation - drug effects | Animals | Quercetin - pharmacology | Lipid Metabolism - drug effects | Phosphatidylinositol 3-Kinases - physiology | Mice | Lipid Peroxidation | CD36 Antigens - physiology | Disease Models, Animal | Fatty liver | Choline | Analysis | Genes | Physiological aspects | Gene expression | Fatty acids
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7. Flavonoids and related compounds in non-alcoholic fatty liver disease therapy
by Pisonero-Vaquero, Sandra and Gonzalez-Gallego, Javier and Sanchez-Campos, Sonia and Garcia-Mediavilla, Maria Victoria
Current Medicinal Chemistry, ISSN 0929-8673, 09/2015, Volume 22, Issue 25, pp. 2991 - 3012
Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of metabolic syndrome, is one of the most common chronic liver diseases, which may... 
Insulin resistance | Lipid accumulation | Flavonoids | Nafld | Antioxidant | Quercetin | TRIGLYCERIDE TRANSFER PROTEIN | INDUCED HEPATIC STEATOSIS | NAFLD | KAPPA-B ACTIVATION | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | ACTIVATED RECEPTOR-GAMMA | NITRIC-OXIDE SYNTHASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GREEN TEA | LIPID-ACCUMULATION | IMPROVES INSULIN-RESISTANCE | quercetin | MITOCHONDRIAL DYSFUNCTION | PHARMACOLOGY & PHARMACY | flavonoids | insulin resistance | lipid accumulation | Animals | Humans | Plant Preparations - pharmacology | Plant Preparations - therapeutic use | Flavonoids - pharmacology | Flavonoids - therapeutic use | Non-alcoholic Fatty Liver Disease - drug therapy
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8. Full Text Functional Interactions between Gut Microbiota Transplantation, Quercetin, and High‐Fat Diet Determine Non‐Alcoholic Fatty Liver Disease Development in Germ‐Free Mice
by Porras, David and Nistal, Esther and Martínez‐Flórez, Susana and Olcoz, José Luis and Jover, Ramiro and Jorquera, Francisco and González‐Gallego, Javier and García‐Mediavilla, María Victoria and Sánchez‐Campos, Sonia
Molecular Nutrition & Food Research, ISSN 1613-4125, 04/2019, Volume 63, Issue 8, pp. e1800930 - n/a
Scope Modulation of intestinal microbiota has emerged as a new therapeutic approach for non‐alcoholic fatty liver disease (NAFLD). Herein, it is addressed... 
flavonoids | non‐alcoholic fatty liver disease | Akkermansia spp | gut–liver axis | gut microbiota transplantation | non-alcoholic fatty liver disease | RESVERATROL | LIPID-METABOLISM | INTESTINAL MICROBIOTA | FOOD SCIENCE & TECHNOLOGY | AKKERMANSIA-MUCINIPHILA | gut-liver axis | HELICOBACTER-PYLORI INFECTION | INSULIN-RESISTANCE | INFLAMMATION | STEATOHEPATITIS | ASSOCIATION | INDUCED OBESITY | Obesity | Fatty liver | Microbiota (Symbiotic organisms) | Isoflavones
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9. Autophagy as a Molecular Target of Flavonoids Underlying their Protective Effects in Human Disease
by Prieto-Domínguez, Nestor and Prieto-Domínguez, Néstor and García-Mediavilla, María V and Garcia-Mediavilla, Maria V and Sanchez-Campos, Sonia and Sánchez-Campos, Sonia and Mauriz, Jose L and Mauriz, José L and Gonzalez-Gallego, Javier and González-Gallego, Javier
Current medicinal chemistry, ISSN 0929-8673, 2018, Volume 25, Issue 7, pp. 814 - 838
Background: Autophagy is a cellular pathway with the ability to maintain cell homeostasis through the elimination of damaged or useless cellular components,... 
Flavonoids | autophagy | infectious diseases | hepatic diseases | cancer | cardiovascular diseases | neurodegenerative disorders | diabetes | HEPATOCELLULAR-CARCINOMA CELLS | OXIDATIVE STRESS | CHEMISTRY, MEDICINAL | APIGENIN-INDUCED APOPTOSIS | FATTY LIVER-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BREAST-CANCER CELLS | ROTENONE-INDUCED NEUROTOXICITY | REACTIVE OXYGEN | HELICOBACTER-PYLORI INFECTION | A VIRUS-INFECTION | PHARMACOLOGY & PHARMACY | CELL-DEATH INDUCTION | Diabetes Mellitus - pathology | Influenza, Human - pathology | Cardiovascular Diseases - drug therapy | Humans | Liver Diseases - pathology | Stomach Ulcer - pathology | Osteoporosis - drug therapy | Cardiovascular Diseases - pathology | Neurodegenerative Diseases - drug therapy | Leishmaniasis - pathology | Autophagy - drug effects | Flavonoids - pharmacology | Influenza, Human - drug therapy | Neurodegenerative Diseases - pathology | Diabetes Mellitus - drug therapy | Stomach Ulcer - drug therapy | Leishmaniasis - drug therapy | Asthma - drug therapy | Neoplasms - drug therapy | Osteoporosis - pathology | Cell Proliferation - drug effects | Liver Diseases - drug therapy | Neoplasms - pathology | Asthma - pathology | Flavonoids - chemistry | Deregulation | Identification methods | Medical services | Homeostasis | Autophagy | Neuromodulation | Modulators | Metabolites | Heart diseases | Vector-borne diseases | Liver diseases | Cell survival | Neurodegenerative diseases | Invasiveness | Medical treatment | Leishmaniasis | Survival | Diseases | Side effects | Cell death | Ulcers | Influenza | Documents | In vivo methods and tests | Diabetes | Cardiovascular diseases | Phagocytosis | Cancer
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10. Full Text A comparison of the effects of kaempferol and quercetin on cytokine-induced pro-inflammatory status of cultured human endothelial cells
by Crespo, Irene and García-Mediavilla, María V and Gutiérrez, Belén and Sánchez-Campos, Sonia and Tuñón, María J and González-Gallego, Javier
British Journal of Nutrition, ISSN 0007-1145, 11/2008, Volume 100, Issue 5, pp. 968 - 976
We investigated the effects of the flavonols kaempferol and quercetin on the expression of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion... 
Adhesion molecules | Flavonoids | Inflammation | Endothelial cells | OXIDATIVE STRESS | NITRIC-OXIDE SYNTHASE | ADHESION MOLECULE EXPRESSION | NUTRITION & DIETETICS | INHIBITION | GENE-EXPRESSION | HYDROGEN-PEROXIDE | ACTIVATOR PROTEIN-1 | NF-KAPPA-B | UP-REGULATION | Transcription Factor AP-1 - analysis | Anti-Inflammatory Agents - pharmacology | Humans | Biomarkers - analysis | Cells, Cultured | Umbilical Veins | Cyclooxygenase 2 - analysis | Endothelial Cells - immunology | Nitric Oxide Synthase Type II - analysis | Analysis of Variance | Quercetin - pharmacology | Electrophoretic Mobility Shift Assay | Kaempferols - pharmacology | Vascular Cell Adhesion Molecule-1 - analysis | Cytokines - pharmacology | E-Selectin - analysis | Endothelial Cells - drug effects | Intercellular Adhesion Molecule-1 - analysis | NF-kappa B - analysis | Tissue | Nutrition research | Free radicals | Comparative studies | Bacteria | Gene expression | Binding sites | Cell adhesion & migration
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11. Full Text A Network Involving Gut Microbiota, Circulating Bile Acids, and Hepatic Metabolism Genes That Protects Against Non‐Alcoholic Fatty Liver Disease
by Petrov, Petar Dianov and García‐Mediavilla, Maria Victoria and Guzmán, Carla and Porras, David and Nistal, Esther and Martínez‐Flórez, Susana and Castell, José Vicente and González‐Gallego, Javier and Sánchez‐Campos, Sonia and Jover, Ramiro
Molecular Nutrition & Food Research, ISSN 1613-4125, 10/2019, Volume 63, Issue 20, pp. e1900487 - n/a
Scope Gut microbiota contributes to non‐alcoholic fatty liver disease (NAFLD) pathogenesis by multiple mechanisms not yet completely understood. Novel... 
bile acids | non‐alcoholic fatty liver disease | gut–liver axis | gut microbiota | hepatic metabolism | non-alcoholic fatty liver disease | INTESTINAL MICROBIOTA | FOOD SCIENCE & TECHNOLOGY | PREVALENCE | IDENTIFICATION | NUCLEAR RECEPTOR | QUERCETIN | gut-liver axis | INFLAMMATION | DYSBIOSIS | STEATOHEPATITIS | EXPRESSION | PROGRESSION | Physiological aspects | Fatty liver | Bile acids | Microbiota (Symbiotic organisms) | Analysis | Genes
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12. Full Text Differential shape of geminivirus mutant spectra across cultivated and wild hosts with invariant viral consensus sequences
by Sánchez-Campos, Sonia and Domínguez-Huerta, Guillermo and Díaz-Martínez, Luis and Tomás, Diego M and Navas-Castillo, Jesús and Moriones, Enrique and Grande-Pérez, Ana
Frontiers in Plant Science, ISSN 1664-462X, 07/2018, Volume 9, p. 932
Geminiviruses (family Geminiviridae) possess single-stranded circular DNA genomes that are replicated by cellular polymerases in plant host cell nuclei. In... 
Tomato yellow leaf curl virus | Host adaptation | Geminivirus | Begomovirus mutant spectra | SsDNA virus quasispecies | Begomovirus | Viral fitness | Emergent viruses | LEAF-CURL-VIRUS | CAPSID PROTEIN | begomovirus | viral fitness | emergent viruses | EVOLUTIONARY GENETICS | NUCLEOTIDE SUBSTITUTION | tomato yellow leaf curl virus | PLANT RNA VIRUSES | PHYLOGENETIC EVIDENCE | PHI-29 DNA-POLYMERASE | geminivirus | PLANT SCIENCES | MEDITERRANEAN BASIN | host adaptation | POSITIVE SELECTION | begomovirus mutant spectra | ssDNA virus quasispecies | SARDINIA-VIRUS | Genetic aspects | Host-virus relationships | Gene mutations | DNA viruses | Health aspects
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