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Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 763 - 10
The N-terminal fusion peptide (FP) of the human immunodeficiency virus (HIV)-1 envelope glycoprotein (Env) gp41 subunit plays a critical role in cell entry.... 
INTERMOLECULAR DISULFIDE BOND | SITE | HEMAGGLUTININ | MULTIDISCIPLINARY SCIENCES | GP41 | ENV TRIMERS | ANTIBODY | INFLUENZA-VIRUS | CRYO-EM STRUCTURE | DEPENDENT EPITOPE | GP140 TRIMERS | Peptides | Glycoprotein gp41 | Human immunodeficiency virus--HIV | Crystallization | Glycoprotein | Antibodies | Tryptophan | Viruses | Glycoproteins | Trimers | Vaccines | Crystal structure
Journal Article
Immunity, ISSN 1074-7613, 07/2018, Volume 49, Issue 1, pp. 14 - 15
The HIV-1 fusion peptide is a target for broadly neutralizing antibodies. In a recent issue of Nature Medicine, Xu et al. (2018) provide proof-of-concept that... 
INFECTION | FUSION PEPTIDE | IMMUNOLOGY | NEUTRALIZING ANTIBODY | VACCINE DESIGN | Viral antibodies | Biological products | Peptides | Analysis | Vaccination | Antibodies | HIV (Viruses)
Journal Article
Journal Article
Journal Article
AIDS Research and Human Retroviruses, ISSN 0889-2229, 09/2018, Volume 34, Issue 9, pp. 79 - 793
Broadly neutralizing antibodies (bNAbs) such as PGDM1400 show promise as prophylactic and therapeutic agents against HIV-1. Human immune system mice were... 
Original Research | HIV-1 | broadly neutralizing antibody | human immune system mouse | PGDM1400 | prophylactic agent | INFECTIOUS DISEASES | VIROLOGY | IN-VIVO | IMMUNOLOGY | Immunization | Neutralizing | Human immunodeficiency virus--HIV | Antibodies | Pharmacology | Vaccines | Chemical compounds | Blood levels | Immune system
Journal Article
Virology, ISSN 0042-6822, 01/2013, Volume 435, Issue 1, pp. 46 - 56
The need for an effective vaccine to prevent the global spread of human immunodeficiency virus type 1 (HIV-1) is well recognized. Passive immunization and... 
Infection | Envelopes | Reviews | Antibodies | Glycoproteins | Epitopes | Immunization (passive) | Vaccines
Journal Article
The Lancet HIV, ISSN 2352-3018, 05/2019, Volume 6, Issue 5, pp. e271 - e272
Journal Article
PLoS Pathogens, ISSN 1553-7366, 08/2015, Volume 11, Issue 8
  The broadly neutralizing HIV monoclonal antibodies (bnMAbs) PG9, PG16, PGT151, and PGT152 have been shown earlier to occasionally display an unusual virus... 
Immunoglobulins | Funding | Cloning | Viruses | Infections | Vaccines | Chromatography | Proteins | Consortia | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Data collection | Binding sites
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 43, p. E6639
  Natural infections expose the immune system to escalating antigen and inflammation over days to weeks, whereas nonlive vaccines are single bolus events. We... 
Antigens | Immunoglobulins | Immunization | Infections | Inflammation | Immune system
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 11/2010, Volume 16, Issue 33, pp. 3716 - 3728
The envelope glycoprotein complex (Env) is responsible for entry of the human immunodeficiency virus type 1 (HIV-1) into cells by mediating attachment to... 
Resistance | Antiviral peptide | T20 | Enfuvirtide | Hiv | Virip | Fusion inhibitors | Virus entry | fusion inhibitors | TERMINAL HEPTAD REPEATS | enfuvirtide | TYPE-1 ENTRY INHIBITORS | REVERSE-TRANSCRIPTASE | ENVELOPE GLYCOPROTEIN | PEPTIDE INHIBITOR | HUMAN-IMMUNODEFICIENCY-VIRUS | antiviral peptide | resistance | 6-HELIX BUNDLE FORMATION | HIV | VIRAL MEMBRANE-FUSION | virus entry | VIRIP | PHARMACOLOGY & PHARMACY | IN-VITRO SYNERGY | CELL-CELL FUSION | Drug Carriers - therapeutic use | HIV Fusion Inhibitors - chemistry | Humans | Drug Resistance, Viral | Peptide Fragments - pharmacology | env Gene Products, Human Immunodeficiency Virus - metabolism | Molecular Targeted Therapy | Virus Internalization - drug effects | Drug Carriers - chemistry | HIV Fusion Inhibitors - administration & dosage | Drug Design | Protein Interaction Domains and Motifs | env Gene Products, Human Immunodeficiency Virus - chemistry | HIV-1 - metabolism | HIV-1 - drug effects | Peptide Fragments - administration & dosage | HIV Fusion Inhibitors - pharmacology | Drug Carriers - pharmacology | HIV Fusion Inhibitors - therapeutic use | alpha 1-Antitrypsin - administration & dosage | Peptide Fragments - chemistry | alpha 1-Antitrypsin - therapeutic use | Animals | alpha 1-Antitrypsin - pharmacology | HIV Infections - drug therapy | Peptide Fragments - therapeutic use
Journal Article
Retrovirology, ISSN 1742-4690, 12/2011, Volume 8, Issue S2, pp. O39 - O39
Journal Article
Science, ISSN 0036-8075, 12/2013, Volume 342, Issue 6165, pp. 1477 - 1483
Journal Article