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allergy (11) 11
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Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 134, Issue 1, pp. 82 - 91
Background Atopic dermatitis (AD; eczema) is characterized by a widespread abnormality in cutaneous barrier function and propensity to inflammation. Filaggrin... 
Allergy and Immunology | single molecule | Atopic dermatitis | transcriptome | eczema | skin | tissue | filaggrin | direct RNA sequencing | gene expression | STRATUM-CORNEUM | BARRIER FUNCTION | RISK | DOWN-REGULATES FILAGGRIN | IMMUNOLOGY | CELL-DEATH | LIPID ORGANIZATION | ICHTHYOSIS VULGARIS | ALLERGY | GENE-EXPRESSION | MUTATIONS | Dermatitis, Atopic - genetics | Intermediate Filament Proteins - immunology | Skin - metabolism | Humans | Gene Expression Regulation | Male | Dermatitis, Atopic - pathology | Lipid Metabolism - immunology | Case-Control Studies | Extracellular Space - immunology | Young Adult | Adolescent | Dermatitis, Atopic - immunology | Intermediate Filament Proteins - genetics | Transcription, Genetic - immunology | Female | High-Throughput Nucleotide Sequencing | Child | Dermatitis, Atopic - metabolism | Skin - pathology | Skin - immunology | Pediatrics | Care and treatment | Skin | Analysis | Proteins | Genotype & phenotype | Biopsy | Quality control | Lipids | Genomes | Mutation | Stress response | Gene expression | Dermatitis | Deoxyribonucleic acid--DNA | Apoptosis | eQTL, Expression quantitative trait loci | AD, Atopic dermatitis | FLG, Filaggrin gene | CILP, Cartilage intermediate layer protein gene | DRS, Direct RNA sequencing | FDR, False discovery rate | GO, Gene ontology | STAT, Signal transducer and activator of transcription | Atopic Dermatitis and Skin Disease
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 132, Issue 5, pp. 1121 - 1129
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 129, Issue 4, pp. 1031 - 1039.e1
Background Filaggrin (FLG) mutations result in reduced stratum corneum (SC) natural moisturizing factor (NMF) components and consequent increased SC pH.... 
Allergy and Immunology | skin barrier | transepidermal water loss | confocal Raman spectroscopy | Flgft/Flgft (FlgdelAPfal) mice | Atopic dermatitis | IL-1 | IL-18 | FLG gene mutations | eczema | filaggrin | natural moisturizing factor | UNCONVENTIONAL PROTEIN SECRETION | INTERLEUKIN-1 RECEPTOR ANTAGONIST | TERM CULTURE | IMMUNOLOGY | PERMEABILITY BARRIER HOMEOSTASIS | HUMAN KERATINOCYTES | IN-VITRO | ALLERGY | Flg(ft)/Flg(ft)(Flg(delAPfal)) mice | EPIDERMIS | IL-1-BETA | Interleukin-1 - genetics | Interleukin-1 - metabolism | Dermatitis, Atopic - genetics | Cytokines - metabolism | Skin - metabolism | Humans | Mice, Inbred C57BL | Child, Preschool | Genotype | Infant | Male | Mice, Knockout | Animals | Adolescent | Alleles | Intermediate Filament Proteins - genetics | Female | Mice | Mutation | Child | Dermatitis, Atopic - metabolism | Intermediate Filament Proteins - metabolism | Hydrogen-Ion Concentration | Medical colleges | Cytokines | Proteases | Genes | Respiratory agents | Genetic aspects | Skin | Inflammation | Universities and colleges | Dermatitis | Proteins | Enzymes | Genotype & phenotype | Hypotheses | Families & family life | Values | Homeostasis | Animal models | Stratum corneum | Interleukin 1 receptor antagonist | Proteinase | Keratinocytes | mRNA | Filaggrin | Raman spectroscopy | pH effects | Tails | Interleukin 18 | Polymerase chain reaction | Water loss | Primers | Interleukin 1 | Interleukin 8 | FLG | SC, Stratum corneum | Flgft | Patient homozygous for null alleles (ie, 2 null alleles) | AD, Atopic dermatitis | FLG, Filaggrin gene | Homozygote wild-type (ie, 0 null alleles) | TEWL, Transepidermal water loss | Heterozygote null allele | Flgft (FlgdelAPfal) mice | IL-1RA, IL-1 receptor antagonist | wild-type (ie, 1 null allele) | NMF, Natural moisturizing factor | ADFLG, AD with FLG mutations | Atopic Dermatitis and Skin Disease | NESS, Nottingham Eczema Severity Score | ADNON-FLG, AD without FLG mutations
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2010, Volume 126, Issue 3, pp. 574 - 580.e1
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2009, Volume 124, Issue 3, pp. R2 - R6
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2008, Volume 122, Issue 3, pp. 560 - 568.e4
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2008, Volume 121, Issue 4, pp. 940 - 946.e3
Journal Article