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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2010, Volume 107, Issue 2, pp. 604 - 609
Journal Article
Nature communications, ISSN 2041-1723, 2011, Volume 2, Issue 1, pp. 599 - 599
Human IgG3 displays the strongest effector functions of all IgG subclasses but has a short half-life for unresolved reasons. Here we show that IgG3 binds to... 
COMPLEX | CHIMERIC ANTIBODIES | GAMMA RECEPTORS | SUBCLASSES | AFFINITY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | I-RELATED RECEPTOR | BINDING DOMAIN | IMMUNOGLOBULIN-G | ANTIGEN | Pneumococcal Infections - drug therapy | Agammaglobulinemia - immunology | Pneumococcal Infections - metabolism | Arginine - immunology | Humans | Receptors, Fc - metabolism | Half-Life | Antibodies, Monoclonal - therapeutic use | Histidine - metabolism | Agammaglobulinemia - metabolism | Streptococcus pneumoniae - immunology | Histocompatibility Antigens Class I - metabolism | Protein Transport - immunology | Agammaglobulinemia - pathology | Pneumococcal Infections - immunology | Agammaglobulinemia - drug therapy | Immunoglobulin G - immunology | Arginine - genetics | Antibodies, Monoclonal - immunology | Molecular Targeted Therapy - methods | Disease Models, Animal | Binding, Competitive | Streptococcus pneumoniae - drug effects | Histocompatibility Antigens Class I - immunology | Histidine - genetics | Immunoglobulin G - therapeutic use | Histidine - immunology | Immunoglobulin G - administration & dosage | Animals | Receptors, Fc - immunology | Antibodies, Monoclonal - administration & dosage | Cell Line, Tumor | Protein Binding | Mice | Antibodies, Monoclonal - metabolism | Arginine - metabolism | Amino Acid Substitution | Hydrogen-Ion Concentration | Immunoglobulin G - metabolism | Index Medicus
Journal Article
Nature Nanotechnology, ISSN 1748-3387, 02/2019, Volume 14, Issue 2, pp. 184 - 190
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2011, Volume 108, Issue 24, pp. 9927 - 9932
Cross-presentation of IgG-containing immune complexes (ICs) is an important means by which dendritic cells (DCs) activate CD8⁺ T cells, yet it proceeds by an... 
T lymphocytes | Antigens | Fc receptors | Cross priming | Dendritic cells | Internalization | Phagosomes | pH | Inflammation | Oxidation | MHC CLASS-I | GAMMA-RECEPTOR | CD8(+) | VIVO | MULTIDISCIPLINARY SCIENCES | DISEASE | MONOCYTES | ANTIGEN PRESENTATION | MYASTHENIA-GRAVIS | T-CELLS | CUTTING EDGE | Dextran Sulfate | Membrane Glycoproteins - metabolism | Cytosol - immunology | Dendritic Cells - immunology | Receptors, Fc - metabolism | NADPH Oxidases - metabolism | NADPH Oxidases - immunology | Vacuolar Proton-Translocating ATPases - metabolism | Receptors, IgG - metabolism | Histocompatibility Antigens Class I - metabolism | Vacuolar Proton-Translocating ATPases - immunology | Phagosomes - immunology | Flow Cytometry | Immunoglobulin G - immunology | Colitis - chemically induced | Membrane Glycoproteins - immunology | Colitis - immunology | Dendritic Cells - metabolism | rab GTP-Binding Proteins - metabolism | CD11b Antigen - immunology | Mice, Inbred C57BL | Phagosomes - metabolism | Histocompatibility Antigens Class I - immunology | Mice, Transgenic | Histocompatibility Antigens Class I - genetics | Receptors, IgG - immunology | NADPH Oxidase 2 | Blotting, Western | CD8 Antigens - immunology | Mice, Knockout | CD8 Antigens - metabolism | Animals | Immunoglobulin G - genetics | Receptors, Fc - immunology | Cross-Priming - immunology | rab GTP-Binding Proteins - immunology | Colitis - metabolism | Protein Binding | rab27 GTP-Binding Proteins | Antigens - immunology | Cytosol - metabolism | Receptors, Fc - genetics | Mice | CD11b Antigen - metabolism | Mutation | Hydrogen-Ion Concentration | Immunoglobulin G - metabolism | Proteins | Signal transduction | Immunoglobulins | Evolution & development | Cells | Index Medicus | Biological Sciences
Journal Article
Nature nanotechnology, ISSN 1748-3387, 02/2019, Volume 14, Issue 4, pp. 398 - 398
In the Supplementary Information file originally published with this Article, the Supplementary references 48-62 were missing; the amended file has now been... 
Antibodies | Antigens | Immunological tolerance
Journal Article
Scientific Reports, ISSN 2045-2322, 11/2016, Volume 6, Issue 1, pp. 37457 - 37457
During infection with non-enveloped viruses, antibodies stimulate immunity from inside cells by activating the cytosolic Fc receptor TRIM21. This intracellular... 
LIMITS | AFFINITY MATURATION | MULTIDISCIPLINARY SCIENCES | RECEPTOR TRIM21 | OFF-RATE | INFECTION | HEXON | VIRUS NEUTRALIZATION | Immunoglobulins | Immune response | Opsonization | Antibodies | Infections | Cytosol | Immune response (humoral) | Fc receptors | Mutagenesis | Antiviral activity | Immunity (humoral) | Affinity | Kinetics | Intracellular | Viral infections | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 14648 - 12
Albumin has a serum half-life of three weeks in humans and is utilized to extend the serum persistence of drugs that are genetically fused or conjugated... 
HALF-LIFE | PH-DEPENDENT BINDING | HEAVY-CHAIN | HOMEOSTASIS | EXOCYTOSIS | DRUG-DELIVERY | HUMAN SERUM-ALBUMIN | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | I-RELATED RECEPTOR | IGG | Albumin | Neonates | Fc receptors | Animal models | Drug development
Journal Article
Journal Article
Antibodies, ISSN 2073-4468, 05/2019, Volume 8, Issue 2, p. 32
Monoclonal antibodies (mAbs) are valuable as research reagents, in diagnosis and in therapy. Their high specificity, the ease in production, favorable... 
Antigens | Therapy | Immunoglobulins | Disease | Peptides | Lymphocytes T | T cell receptors | Cell surface | T-cell receptor | Receptors | Cell activation | Major histocompatibility complex | Lymphocytes | Reagents | Monoclonal antibodies | Diabetes | Diagnosis | Autoimmune diseases | Histocompatibility | Cancer | MHC | epitope | TCR-like antibodies | antigen-specific therapy
Journal Article
Journal Article