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PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e62097 - e62097
Journal Article
Journal Article
Gene Therapy, ISSN 0969-7128, 07/2010, Volume 17, Issue 7, pp. 815 - 826
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 6, pp. e11306 - e11306
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2008, Volume 105, Issue 39, pp. 15112 - 15117
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2013, Volume 110, Issue 10, pp. 4045 - 4050
Glaucoma, a major cause of blindness worldwide, is a neurodegenerative optic neuropathy in which vision loss is caused by loss of retinal ganglion cells... 
Glaucoma | Axons | Optic nerve | Eyes | Cell death | Neurons | Small interfering RNA | Mice | Physical trauma | Ganglia | Neuroprotection | Drug discovery | MAP3K12 | ELECTROPORATION | INHIBITOR SELECTIVITY | MULTIDISCIPLINARY SCIENCES | AXONAL REGENERATION | INJURY | DEGENERATION | drug discovery | PATHWAY | neuroprotection | IN-VIVO | NEURONS | MOUSE RETINA | GLAUCOMA | Glaucoma - etiology | Up-Regulation | Rats, Wistar | Humans | Cell Survival - genetics | Male | Retinal Ganglion Cells - pathology | Optic Nerve Diseases - pathology | Cell Death - genetics | RNA Interference | Optic Nerve Injuries - pathology | MAP Kinase Kinase Kinases - antagonists & inhibitors | Cell Survival - physiology | Disease Models, Animal | Optic Nerve Injuries - drug therapy | Cell Survival - drug effects | Retinal Ganglion Cells - enzymology | Signal Transduction | MAP Kinase Kinase Kinases - genetics | Down-Regulation | Cells, Cultured | Rats | Glaucoma - drug therapy | Piperazines - pharmacology | Optic Nerve Injuries - enzymology | Animals | Cell Death - physiology | MAP Kinase Kinase Kinases - physiology | Protein Kinase Inhibitors - pharmacology | Optic Nerve Diseases - etiology | Retinal Ganglion Cells - drug effects | Genomics | Physiological aspects | Retina | Genetic aspects | Research | Health aspects | Genetic screening | Methods | Mitogen-activated protein kinases | Signal transduction | Rodents | Kinases | Cells | Apoptosis | Index Medicus | Biological Sciences
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2012, Volume 109, Issue 6, pp. 2132 - 2137
Hereditary retinal blindness is caused by mutations in genes expressed in photoreceptors or retinal pigment epithelium. Gene therapy in mouse and dog models of... 
Eyes | Disease vectors | Disease models | Canines | Retinitis pigmentosa | Photoreceptors | Retina | Gene therapy | Retinal diseases | Genetic mutation | Retinal degeneration | MUTATION ANALYSIS | retinal degeneration | LEBER CONGENITAL AMAUROSIS | CHILDHOOD BLINDNESS | CANINE MODEL | retina | CONE VISION | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | RPGR EXON ORF15 | GTPASE REGULATOR RPGR | DISEASE EXPRESSION | Genetic Therapy | Retinal Bipolar Cells - pathology | Humans | Retinitis Pigmentosa - genetics | Genotype | Eye Proteins - therapeutic use | Mutation - genetics | Open Reading Frames - genetics | Blindness - genetics | Protein Transport | Phenotype | Animals | Retinitis Pigmentosa - therapy | Dogs | Opsins - metabolism | Genetic Diseases, X-Linked - genetics | Mice | Blindness - therapy | Eye Proteins - genetics | Photoreceptor Cells, Vertebrate - pathology | Genetic Diseases, X-Linked - therapy | Care and treatment | Blindness | Physiological aspects | Genetic aspects | Research | Health aspects | Proteins | Mutation | Gene expression | Animal models | Translation | Preservation | X chromosome | Clinical trials | Rod outer segment membranes | Nuclei | Promoters | interphotoreceptor retinoid-binding protein | Cones | Bipolar cells | retinal pigment epithelium | Guanosinetriphosphatase | Index Medicus | Biological Sciences
Journal Article