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1. Full Text Abstract IA25: Targeted therapies for hepatocellular carcinoma
by Sangro, Bruno
Cancer Research, ISSN 0008-5472, 11/2017, Volume 77, Issue 22 Supplement, pp. IA25 - IA25
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2. Full Text Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial
by El-Khoueiry, Anthony B, Dr and Sangro, Bruno, MD and Yau, Thomas, MD and Crocenzi, Todd S, MD and Kudo, Masatoshi, MD and Hsu, Chiun, MD and Kim, Tae-You, MD and Choo, Su-Pin, BMBS and Trojan, Jörg, MD and Welling, Theodore H, MD and Meyer, Tim, MD and Kang, Yoon-Koo, MD and Yeo, Winnie, MD and Chopra, Akhil, MD and Anderson, Jeffrey, MD and dela Cruz, Christine, MD and Lang, Lixin, PhD and Neely, Jaclyn, PhD and Tang, Hao, PhD and Dastani, Homa B, PhD and Melero, Ignacio
Lancet, The, ISSN 0140-6736, 2017, Volume 389, Issue 10088, pp. 2492 - 2502
Summary Background For patients with advanced hepatocellular carcinoma, sorafenib is the only approved drug worldwide, and outcomes remain poor. We aimed to... 
Internal Medicine | CELL LUNG-CANCER | MEDICINE, GENERAL & INTERNAL | EFFICACY | SAFETY | IMMUNOTHERAPY | SORAFENIB | BLOCKADE | DOCETAXEL | PD-1 | Drug Administration Schedule | Humans | Antibodies, Monoclonal - adverse effects | Liver Neoplasms - drug therapy | Male | Response Evaluation Criteria in Solid Tumors | Treatment Outcome | Antineoplastic Agents - administration & dosage | Tumor Burden | Dose-Response Relationship, Drug | B7-H1 Antigen - metabolism | Carcinoma, Hepatocellular - drug therapy | Time Factors | Antibodies, Monoclonal - administration & dosage | Antineoplastic Agents - adverse effects | Nivolumab | Carcinoma, Hepatocellular - pathology | Biomarkers, Tumor - metabolism | Female | Liver Neoplasms - pathology | Aged | Virus diseases | Medical colleges | Care and treatment | Cell death | College teachers | Hepatoma | Comparative analysis | Drug approval | Slopes | Therapy | Pemphigoid | Intravenous administration | Inhibitor drugs | PD-1 protein | Funding | Liver | Medical services | Clinical trials | Hepatocellular carcinoma | Lymphocytes T | Infections | Metastasis | Dosage | Cancer therapies | B7 antigen | Acceptability | Incidence | Hepatitis | Liver cancer | Pathways | Quality | Immunotherapy | Safety engineering | Safety management | Safety | Expansion | Drug dosages | Liver diseases | Effectiveness | Mortality | Group dynamics | Patients | Hospitals | Inhibitors | Immune checkpoint | Adults | Solid tumors | Hepatitis C virus | Hepatitis C | Tumors | Apoptosis
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3. Full Text Immunological landscape and immunotherapy of hepatocellular carcinoma
by Prieto, Jesús and Melero, Ignacio and Sangro, Bruno
Nature Reviews Gastroenterology and Hepatology, ISSN 1759-5045, 12/2015, Volume 12, Issue 12, pp. 681 - 700
Advanced hepatocellular carcinoma (HCC) is a serious therapeutic challenge and targeted therapies only provide a modest benefit in terms of overall survival.... 
EPITHELIAL-MESENCHYMAL TRANSITION | TUMOR-INFILTRATING LYMPHOCYTES | PULSED DENDRITIC CELLS | I-RELATED CHAIN | REGULATORY T-CELLS | CHIMERIC ANTIGEN RECEPTOR | SUPPRESSOR-CELLS | GASTROENTEROLOGY & HEPATOLOGY | PHASE-I | INDUCED KILLER-CELLS | NKG2D LIGAND EXPRESSION | Liver Neoplasms - immunology | Immunotherapy - methods | Carcinoma, Hepatocellular - immunology | Carcinoma, Hepatocellular - therapy | Liver Neoplasms - therapy | Humans | Radiofrequency ablation | Usage | Care and treatment | Hepatoma | Immunotherapy | Risk factors
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4. Full Text Yttrium 90 radioembolization for the treatment of hepatocellular carcinoma: Biological lessons, current challenges, and clinical perspectives
by Salem, Riad and Mazzaferro, Vincenzo and Sangro, Bruno
Hepatology, ISSN 0270-9139, 12/2013, Volume 58, Issue 6, pp. 2188 - 2197
SURVIVAL | RANDOMIZED CONTROLLED TRIAL | INDUCED LIVER-DISEASE | Y-90 MICROSPHERES THERASPHERE(R) | PORTAL-VEIN THROMBOSIS | PROGNOSTIC-FACTORS | ARTERIAL EMBOLIZATION | GLASS MICROSPHERES | RESIN MICROSPHERES | TUMOR RESPONSE | GASTROENTEROLOGY & HEPATOLOGY | Chemoembolization, Therapeutic - methods | Liver Transplantation | Humans | Liver Neoplasms - radiotherapy | Middle Aged | Carcinoma, Hepatocellular - radiotherapy | Male | Aged | Clinical Trials as Topic | Yttrium Radioisotopes - therapeutic use | radioembolization | randomized trial | hepatocellular carcinoma
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5. Full Text Immunotherapy of hepatocellular carcinoma: Facts and hopes
by Iñarrairaegui, Mercedes and Melero, Ignacio and Sangro, Bruno
Clinical Cancer Research, ISSN 1078-0432, 04/2018, Volume 24, Issue 7, pp. 1518 - 1524
Treatment of patients with hepatocellular carcinoma (HCC) in the advanced stage remains a great challenge, with very few drugs approved. After decades of... 
PLACEBO | ONCOLOGY | DOUBLE-BLIND | 2ND-LINE TREATMENT | IMMUNE ACTIVATION | CANCER-IMMUNOTHERAPY | PHASE-3 | RADIOTHERAPY | SORAFENIB | BLOCKADE | T-CELLS | PD-1 protein | Clinical trials | Cytotoxicity | Hepatocellular carcinoma | Lymphocytes T | Patients | Immunosuppressive agents | Anticancer properties | Proteins | Liver cancer | CTLA-4 protein | Inhibitors | Immune checkpoint | Cell death | Immunotherapy | Monoclonal antibodies | Biomarkers | Antitumor activity | Synergistic effect | Tumors | Cancer | Apoptosis | Immune system
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6. Full Text Reply
by Sangro, Bruno
Hepatology, ISSN 0270-9139, 03/2012, Volume 55, Issue 3, pp. 981 - 982
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7. Reply
by Bruno Sangro
Hepatology, ISSN 0270-9139, 03/2012, Volume 55, Issue 3, p. 981
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8. Full Text Reply
by Sangro, Bruno
Hepatology, ISSN 0270-9139, 03/2012, Volume 55, Issue 3, pp. 981 - 982
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9. Full Text Reply
by Sangro, Bruno and for the European Network on Radioembolization With Yttrium-90 Resin Microspheres
Hepatology, ISSN 0270-9139, 03/2012, Volume 55, Issue 3, pp. 981 - 982
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10. Full Text Chemoembolization and radioembolization
by Sangro, Bruno, MD, PhD
Best Practice & Research: Clinical Gastroenterology, ISSN 1521-6918, 2014, Volume 28, Issue 5, pp. 909 - 919
Abstract Chemoembolization and radioembolization are at the core of the treatment of patients with hepatocellular carcinoma who cannot receive potentially... 
Gastroenterology and Hepatology | Radioembolization, RE | Yttrium | Transarterial chemoembolization, TACE | Drug-eluting beads, DEB | Selective Internal Radiation Therapy, SIRT | DEB | Selective internal radiation therapy | Transarterial chemoembolization | TACE | Drug-eluting beads | Radioembolization | SIRT | DRUG-ELUTING BEADS | Y-90 MICROSPHERES THERASPHERE(R) | PORTAL-VEIN | PREDISPOSING FACTORS | SURVIVAL ANALYSIS | TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION | UNRESECTABLE HEPATOCELLULAR-CARCINOMA | SUPERSELECTIVE TRANSARTERIAL CHEMOEMBOLIZATION | LIVER-CANCER | 5-YEAR SURVIVAL | GASTROENTEROLOGY & HEPATOLOGY | Radiopharmaceuticals - administration & dosage | Carcinoma, Hepatocellular - therapy | Liver Neoplasms - therapy | Antineoplastic Agents - administration & dosage | Humans | Embolization, Therapeutic - methods
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11. Targets for immunotherapy of liver cancer
by Tim F Greten and Bruno Sangro
Journal of Hepatology, ISSN 0168-8278, 01/2018, Volume 68, Issue 1, p. 157
Drug development in hepatocellular carcinoma (HCC) has been characterised by many failures in the past. Despite good rationales and promising phase II data,... 
Liver cancer | Immune checkpoint | Immunotherapy | Clinical trials | Hepatocellular carcinoma | Drug development
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12. Full Text Beneficio sobre la supervivencia con las técnicas intraarteriales en el carcinoma hepatocelular
by Sangro, Bruno
Gastroenterologia y Hepatologia, ISSN 0210-5705, 2014, Volume 37, Issue 2, pp. 95 - 101
The two intraarterial techniques used in the treatment of hepatocellular carcinoma (HCC) are the transarterial chemoembolization (TACE) and radioembolization... 
Microspheres | Sorafenib | Eluting beads | Radioembolization | Chemoembolization
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13. Full Text Assessment of treatment efficacy in hepatocellular carcinoma: response rate, delay in progression or none of them
by Bruix, Jordi and Reig, Maria and Sangro, Bruno
Journal of Hepatology, ISSN 0168-8278, 2017, Volume 66, Issue 6, pp. 1114 - 1117
Gastroenterology and Hepatology | Treatment Outcome | Carcinoma, Hepatocellular | Liver Neoplasms | Chemoembolization, Therapeutic | Humans | Disease Progression | Care and treatment | Analysis | Cancer
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14. Full Text Beneficio sobre la supervivencia con las técnicas intraarteriales en el carcinoma hepatocelular
by Sangro, Bruno
Gastroenterología y Hepatología, ISSN 0210-5705, 2014, Volume 37, pp. 95 - 101
Resumen Las dos técnicas intraarteriales utilizadas en el tratamiento del carcinoma hepatocelular (CHC) son la quimioembolización transarterial (TACE) y la... 
Gastroenterology and Hepatology | Microspheres | Sorafenib | Radioembolización | Partículas eluyentes | Eluting beads | Quimioembolización | Radioembolization | Microesferas | Chemoembolization
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15. Full Text Survival benefit with intraarterial techniques in hepatocellular carcinoma
by Sangro, Bruno
Gastroenterologia y hepatologia, ISSN 0210-5705, 07/2014, Volume 37 Suppl 2, p. 95
The two intraarterial techniques used in the treatment of hepatocellular carcinoma (HCC) are the transarterial chemoembolization (TACE) and radioembolization... 
Chemoembolization, Therapeutic - methods | Carcinoma, Hepatocellular - mortality | Humans | Brachytherapy - methods | Survival Rate | Carcinoma, Hepatocellular - therapy | Liver Neoplasms - therapy | Liver Neoplasms - mortality | Injections, Intra-Arterial
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16. Evidence-based integration of selective internal radiation therapy into hepatocellular carcinoma management
by Sangro, Bruno
Future Oncology, ISSN 1479-6694, 11/2014, Volume 10, Issue 15, pp. 7 - 11
selective internal radiation therapy | hepatocellular carcinoma | brachytherapy | SURVIVAL | EFFICACY | SAFETY | SORAFENIB | LIVER-CANCER | TRIAL | ONCOLOGY | TRANSARTERIAL CHEMOEMBOLIZATION | RADIOEMBOLIZATION | Y-90 MICROSPHERES
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17. Full Text Targets for immunotherapy of liver cancer
by Greten, Tim F and Sangro, Bruno
Journal of Hepatology, ISSN 0168-8278, 01/2018, Volume 68, Issue 1, pp. 157 - 166
Drug development in hepatocellular carcinoma (HCC) has been characterised by many failures in the past. Despite good rationales and promising phase II data,... 
HCC | Immunotherapy | Cancer | ADVANCED HEPATOCELLULAR-CARCINOMA | DENDRITIC CELLS | CLINICAL-TRIAL | PD-1 BLOCKADE | ACQUIRED-RESISTANCE | UNTREATED MELANOMA | T-CELL-ACTIVATION | POSTOPERATIVE RECURRENCE | PHASE-3 TRIAL | DOUBLE-BLIND | GASTROENTEROLOGY & HEPATOLOGY
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18. Assessment of treatment efficacy in hepatocellular carcinoma: Response rate, delay in progression or none of them
by Jordi Bruix and Maria Reig and Bruno Sangro
Journal of Hepatology, ISSN 0168-8278, 06/2017, Volume 66, Issue 6, p. 1114
Bruix et al present an assessment of treatment efficacy in hepatocellular carcinoma, with focus on response rate, delay in progression, or none of them. The... 
Liver cancer | Medical treatment | Hepatocellular carcinoma | Survival | Clinical outcomes | Tumors
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19. Liver function considerations for post-selective internal radiation therapy resection (hepatocellular carcinoma and metastatic colorectal cancer)
by Sangro, Bruno
Future Oncology, ISSN 1479-6694, 11/2014, Volume 10, Issue 15, pp. 57 - 59
HCC | radioembolization-induced liver disease | REILD | hepatocellular carcinoma | liver metastases | colorectal adenocarcinoma | MICROSPHERES | OXALIPLATIN | FLUOROURACIL | TUMORS | HEPATIC-INJURY | CHEMOTHERAPY | ONCOLOGY | DISEASE | RADIOEMBOLIZATION
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20. Full Text Radioembolization for hepatocellular carcinoma: gaining insight on a personalized approach
by Sangro, Bruno and Rodriguez, Macarena
Liver International, ISSN 1478-3223, 01/2017, Volume 37, Issue 1, pp. 32 - 34
See Article on Page 101 
SURVIVAL | PROGNOSTIC-FACTORS | EFFICACY | GLASS MICROSPHERES | RESIN MICROSPHERES | EXPERIENCE | COLORECTAL LIVER METASTASES | Y-90 RADIOEMBOLIZATION | ALBUMIN | GASTROENTEROLOGY & HEPATOLOGY | RADIATION SEGMENTECTOMY | Microspheres | Humans | Treatment Outcome | Yttrium Radioisotopes | Carcinoma, Hepatocellular | Embolization, Therapeutic | Liver Neoplasms | Radiopharmaceuticals | Hepatocellular carcinoma
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