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Nature Medicine, ISSN 1078-8956, 06/2019, Volume 25, Issue 6, pp. 869 - 869
Vijay Sankaran is a practicing pediatric hematologist and researcher at Boston Children’s Hospital, the Dana-Farber Cancer Institute and the Broad Institute of... 
Genetics | Blood cells | Children
Journal Article
Science, ISSN 0036-8075, 12/2008, Volume 322, Issue 5909, pp. 1839 - 1842
Differences in the amount of fetal hemoglobin (HbF) that persists into adulthood affect the severity of sickle cell disease and the ?-thalassemia syndromes.... 
Protein isoforms | K562 cells | Erythroblasts | Genes | Cell lines | Small interfering RNA | Genetic loci | Reports | Erythroid cells | Gene expression | Hemoglobins | LOCUS-CONTROL REGION | COMPLEX | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | ZINC-FINGER PROTEIN | DIFFERENTIATION | RECRUITS | BETA-THALASSEMIA | LINEAGE | GENOME-WIDE ASSOCIATION | Erythropoiesis | Fetal Hemoglobin - biosynthesis | Multigene Family | Mi-2 Nucleosome Remodeling and Deacetylase Complex | Humans | Erythroblasts - metabolism | gamma-Globins - metabolism | Protein Isoforms - metabolism | RNA Interference | Transcription, Genetic | gamma-Globins - genetics | Nuclear Proteins - genetics | Down-Regulation | Cells, Cultured | Erythroid Cells - metabolism | Gene Expression Regulation | Histone Deacetylases - metabolism | Nuclear Proteins - metabolism | GATA1 Transcription Factor - metabolism | beta-Globins - genetics | Hemoglobinopathies - therapy | Transcription Factors - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | beta-Globins - metabolism | Fetal Hemoglobin - genetics | K562 Cells | Cell Line, Tumor | Erythroid Precursor Cells - metabolism | Mice | Polymorphism, Single Nucleotide | Protein Isoforms - genetics | Sickle cell anemia | Physiological aspects | Thalassemia | Genetic aspects | Risk factors | Fetal hemoglobin | Medical research | Genotype & phenotype | Hematology | Sickle cell disease
Journal Article
British Journal of Haematology, ISSN 0007-1048, 04/2010, Volume 149, Issue 2, pp. 181 - 194
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. SCI-35 - SCI-35
A great body of work has focused on understanding the role that gene regulation at the transcriptional level plays in blood cell production and diseases that... 
Journal Article
Experimental Hematology, ISSN 0301-472X, 2016, Volume 44, Issue 9, pp. S36 - S36
Journal Article
Science (New York, N.Y.), ISSN 0036-8075, 05/2019, Volume 364, Issue 6442, pp. 750 - 750
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 09/2019, Volume 66, Issue 9, pp. e27874 - n/a
Growth factor‐independent 1B (GFI1B) variants are a rare cause of thrombocytopenia. We report on a male child who was initially diagnosed with immune... 
bone marrow failure | GFI1B | hematopoiesis | genetics | thrombocytopenia | immune thrombocytopenia | GFI-1B | CD34 EXPRESSION | ONCOLOGY | MUTATION | PEDIATRICS | HEMATOLOGY | CELL | Thrombocytopenia | Stem cells | Population studies | Genetic diversity | Growth factors | Biological evolution | Gene sequencing
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 03/2016, Volume 1368, Issue 1, pp. 25 - 30
Journal Article
Journal Article
HAEMATOLOGICA, ISSN 0390-6078, 10/2019, Volume 104, Issue 11, pp. 2178 - 2188
Ubiquitination is an enzymatic post-translational modification that affects protein fate. The ubiquitin-proteasome system (UPS) was first discovered in... 
LOCALIZATION | ACTIVATION | PROTEIN | HSP70 | GENE | INEFFECTIVE ERYTHROPOIESIS | HAUSP | HEMATOLOGY | CELL | DEUBIQUITINATING ENZYMES | P53
Journal Article
Pediatric Blood & Cancer, ISSN 1545-5009, 09/2019, Volume 66, Issue 9
Journal Article
ELIFE, ISSN 2050-084X, 05/2019, Volume 8
Genome-wide association studies (GWAS) have identified thousands of variants associated with human diseases and traits. However, the majority of... 
SINGLE-CELL | COMPLEX | RNA-SEQ | BIOLOGY | FETAL-HEMOGLOBIN EXPRESSION | PROVIDES INSIGHT | U2 SNRNP | LOCI | IDENTIFICATION | VARIANT | BLOOD-CELL PRODUCTION | Erythropoiesis | Flow cytometry | Biotechnology | Immunoglobulins | Hematology | Cloning | Genomics | Genes | Oncology | Genomes | Genetic diversity | Blood | Hemopoiesis | Inflammatory bowel disease | Cancer
Journal Article