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1. Full Text Incidence, Predictors, and Mid-Term Outcomes of Possible Leaflet Thrombosis After TAVR
by Yanagisawa, Ryo, MD and Hayashida, Kentaro, MD, PhD and Yamada, Yoshitake, MD, PhD and Tanaka, Makoto, MD and Yashima, Fumiaki, MD and Inohara, Taku, MD, PhD and Arai, Takahide, MD and Kawakami, Takashi, MD, PhD and Maekawa, Yuichiro, MD, PhD and Tsuruta, Hikaru, MD and Itabashi, Yuji, MD, PhD and Murata, Mitsushige, MD, PhD and Sano, Motoaki, MD, PhD and Okamoto, Kazuma, MD, PhD and Yoshitake, Akihiro, MD, PhD and Shimizu, Hideyuki, MD, PhD and Jinzaki, Masahiro, MD, PhD and Fukuda, Keiichi, MD, PhD
JACC: Cardiovascular Imaging, ISSN 1936-878X, 2017, Volume 10, Issue 1, pp. 1 - 11
Abstract Objectives This study sought to clarify the incidence and predictors of hypoattenuated leaflet thickening (HALT) and mid-term outcomes after... 
Cardiovascular | D-dimer | reduced leaflet motion | aortic stenosis | thrombosis | TAVR | SURGERY | CARDIAC & CARDIOVASCULAR SYSTEMS | STENOSIS | TRANSCATHETER | HEART-VALVES | IMPLANTATION | AORTIC-VALVE-REPLACEMENT | PROSTHESIS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Usage | Thrombosis | Patient outcomes | Blood clot | Risk factors | Heart valve replacement | Treatment outcome | Complications and side effects | Analysis | Research | Prevalence studies (Epidemiology)
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2. Full Text Thrombus in acute aortic dissection with atrial fibrillation: a treatment dilemma
by Shiraishi, Yasuyuki, MD and Kohno, Takashi, MD and Egashira, Toru, MD and Maekawa, Yuichiro, MD and Yamada, Yoshitake, MD and Yoshitake, Akihiro, MD and Shimizu, Hideyuki, MD and Sano, Motoaki, MD and Jinzaki, Masahiro, MD and Fukuda, Keiichi, MD
American Journal of Emergency Medicine, ISSN 0735-6757, 2014, Volume 33, Issue 2, pp. 308.e3 - 308.e4
Type B acute aortic dissection (AAD) is often successfully managed with medical therapy, with a lower mortality rate, compared with type A AAD. Although the... 
Emergency | EMERGENCY MEDICINE | Thrombosis - complications | Humans | Atrial Fibrillation - complications | Anticoagulants - therapeutic use | Male | Tomography, X-Ray Computed | Aortic Aneurysm - complications | Aortic Diseases - drug therapy | Aneurysm, Dissecting - complications | Aortic Diseases - complications | Aneurysm, Dissecting - diagnostic imaging | Aged | Thrombosis - drug therapy | Aortic Aneurysm - diagnostic imaging | Drug therapy | Thrombosis | Atrial fibrillation | Surgery | Blood clot | Anticoagulants | Mortality | Older people | Ulcers | Tomography | Blood pressure | Dissection | Patients | Blood clots
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3. Full Text Impact of Subclinical Vascular Complications Detected by Systematic Postprocedural Multidetector Computed Tomography After Transcatheter Aortic Valve Implantation Using Balloon-Expandable Edwards SAPIEN XT Heart Valve
by Kakefuda, Yuki and Hayashida, Kentaro and Yamada, Yoshitake and Yashima, Fumiaki and Inohara, Taku and Yanagisawa, Ryo and Tanaka, Makoto and Arai, Takahide and Kawakami, Takashi and Maekawa, Yuichiro and Tsuruta, Hikaru and Itabashi, Yuji and Murata, Mitsushige and Sano, Motoaki and Okamoto, Kazuma and Yoshitake, Akihiro and Shimizu, Hideyuki and Jinzaki, Masahiro and Fukuda, Keiichi
The American Journal of Cardiology, ISSN 0002-9149, 04/2017, Volume 119, Issue 7, pp. 1100 - 1105
Complications after transcatheter aortic valve implantation (TAVI) remain an important issue. This study aimed to evaluate the impact of systematic... 
REPLACEMENT | INCIDENTAL FINDINGS | CARDIAC & CARDIOVASCULAR SYSTEMS | STENOSIS | Transcatheter Aortic Valve Replacement - instrumentation | Multidetector Computed Tomography | Heart Valve Prosthesis | Humans | Risk Factors | Male | Prosthesis Design | Contrast Media | Aged, 80 and over | Female | Iopamidol | Radiographic Image Interpretation, Computer-Assisted | Postoperative Complications - diagnostic imaging | Heart valve diseases | Complications and side effects | Medical colleges | CT imaging | Cardiology | Hypertension | Heart | Intensive care | Kidneys | Enrollments | Cardiovascular disease | Patients | Abdomen | Variables | Ostomy | Rodents | Coronary vessels | Work stations | Tomography | Standard deviation
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4. Full Text A shared neural ensemble links distinct contextual memories encoded close in time
by Cai, Denise J and Aharoni, Daniel and Shuman, Tristan and Shobe, Justin and Biane, Jeremy and Song, Weilin and Wei, Brandon and Veshkini, Michael and La-Vu, Mimi and Lou, Jerry and Flores, Sergio E and Kim, Isaac and Sano, Yoshitake and Zhou, Miou and Baumgaertel, Karsten and Lavi, Ayal and Kamata, Masakazu and Tuszynski, Mark and Mayford, Mark and Golshani, Peyman and Silva, Alcino J
Nature, ISSN 0028-0836, 05/2016, Volume 534, Issue 7605, pp. 115 - 118
Recent studies suggest that a shared neural ensemble may link distinct memories encoded close in time(1-12). According to the memory allocation... 
TRACE | HIPPOCAMPUS | SYSTEM | FEAR MEMORY | MULTIDISCIPLINARY SCIENCES | ENVIRONMENT | RECALL | MICE | ALLOCATION | PLACE | INTRINSIC NEURONAL EXCITABILITY | CA1 Region, Hippocampal - cytology | CA1 Region, Hippocampal - physiology | Mice, Inbred C57BL | Male | Calcium - analysis | Fear | Animals | Time Factors | Mental Recall - physiology | Neurons - physiology | Mice | Models, Neurological | Memory - physiology | Encoding (Memory) | Methods | Neurological research | Memory | Research | Learning | Brain | Neurosciences | Neurons
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5. Full Text Synaptic tagging during memory allocation
by Rogerson, Thomas and Cai, Denise J and Frank, Adam and Sano, Yoshitake and Shobe, Justin and Lopez-Aranda, Manuel F and Silva, Alcino J
Nature Reviews Neuroscience, ISSN 1471-003X, 2014, Volume 15, Issue 3, pp. 157 - 169
There is now compelling evidence that the allocation of memory to specific neurons (neuronal allocation) and synapses (synaptic allocation) in a neurocircuit... 
DENDRITIC SPINES | HIPPOCAMPAL SLICES | DECLARATIVE MEMORY | ALZHEIMERS-DISEASE | IN-VIVO | ELEMENT-BINDING PROTEIN | SPATIAL MEMORY | LONG-TERM POTENTIATION | AMYGDALA NEURONS | NEUROSCIENCES | CA1 PYRAMIDAL NEURONS | Animals | Neuronal Plasticity - physiology | Synapses - physiology | Humans | Dendritic Spines - physiology | Neurons - physiology | Models, Neurological | Hippocampus - physiology | Nerve Net - physiology | Memory - physiology | Physiological aspects | Neural networks | Research
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6. Full Text Insights into Land Plant Evolution Garnered from the Marchantia polymorpha Genome
by Bowman, John L and Kohchi, Takayuki and Yamato, Katsuyuki T and Jenkins, Jerry and Shu, Shengqiang and Ishizaki, Kimitsune and Yamaoka, Shohei and Nishihama, Ryuichi and Nakamura, Yasukazu and Berger, Frédéric and Adam, Catherine and Aki, Shiori Sugamata and Althoff, Felix and Araki, Takashi and Arteaga-Vazquez, Mario A and Balasubrmanian, Sureshkumar and Barry, Kerrie and Bauer, Diane and Boehm, Christian R and Briginshaw, Liam and Caballero-Perez, Juan and Catarino, Bruno and Chen, Feng and Chiyoda, Shota and Chovatia, Mansi and Davies, Kevin M and Delmans, Mihails and Demura, Taku and Dierschke, Tom and Dolan, Liam and Dorantes-Acosta, Ana E and Eklund, D. Magnus and Florent, Stevie N and Flores-Sandoval, Eduardo and Fujiyama, Asao and Fukuzawa, Hideya and Galik, Bence and Grimanelli, Daniel and Grimwood, Jane and Grossniklaus, Ueli and Hamada, Takahiro and Haseloff, Jim and Hetherington, Alexander J and Higo, Asuka and Hirakawa, Yuki and Hundley, Hope N and Ikeda, Yoko and Inoue, Shin-ichiro and Inoue, Keisuke and Ishida, Sakiko and Jia, Qidong and Kakita, Mitsuru and Kanazawa, Takehiko and Kawai, Yosuke and Kawashima, Tomokazu and Kennedy, Megan and Kinose, Keita and Kinoshita, Toshinori and Kohara, Yuji and Koide, Eri and Komatsu, Kenji and Kopischke, Sarah and Kubo, Minoru and Kyozuka, Junko and Lagercrantz, Ulf and Lin, Shih-Shun and Lindquist, Erika and Lipzen, Anna M and Lu, Chia-Wei and De Luna, Efraín and Martienssen, Robert A and Minamino, Naoki and Mizutani, Miya and Mizutani, Masaharu and Mochizuki, Nobuyoshi and Monte, Isabel and Mosher, Rebecca and Nagasaki, Hideki and Nakagami, Hirofumi and Naramoto, Satoshi and Nishitani, Kazuhiko and Ohtani, Misato and Okamoto, Takashi and Okumura, Masaki and Phillips, Jeremy and Pollak, Bernardo and Reinders, Anke and Rövekamp, Moritz and Sano, Ryosuke and Sawa, Shinichiro and Schmid, Marc W and Shirakawa, Makoto and Solano, Roberto and Spunde, Alexander and Suetsugu, Noriyuki and Sugano, Sumio and Sugiyama, Akifumi and Sun, Rui and Suzuki, Yutaka and Takenaka, Mizuki and ... and Univ. of California, Oakland, CA (United States) and Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States). National Energy Research Scientific Computing Center (NERSC) and Teknisk-naturvetenskapliga vetenskapsområdet and Biologiska sektionen and Uppsala universitet and Växtekologi och evolution and Institutionen för ekologi och genetik
Cell, ISSN 0092-8674, 10/2017, Volume 171, Issue 2, pp. 287 - 304.e15
The evolution of land flora transformed the terrestrial environment. Land plants evolved from an ancestral charophycean alga from which they inherited... 
Marchantia polymorpha | auxin | sex chromosome | land plant evolution | charophycean algae | TRANSCRIPTION FACTORS | COMPLETE SEQUENCE | RNA-SEQ | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALLENE OXIDE CYCLASE | ORTHOLOG GROUPS | RECEPTOR-LIKE KINASES | DOSAGE-SENSITIVITY | ABSCISIC-ACID | POLAR ORGANIZERS | MOSS PHYSCOMITRELLA-PATENS | CELL BIOLOGY | Biological Evolution | Signal Transduction | Molecular Sequence Annotation | Gene Expression Regulation, Plant | Adaptation, Biological | Marchantia - physiology | Transcription, Genetic | Embryophyta - genetics | Embryophyta - physiology | Genome, Plant | Marchantia - genetics | Evolution | Genetic transcription | Plants | Analysis | Genomics | Plant genetics | Biochemistry & Molecular Biology | BASIC BIOLOGICAL SCIENCES | Cell Biology | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Evolutionsbiologi | Natural Sciences | Evolutionary Biology
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7. Full Text The P element invaded rapidly and caused hybrid dysgenesis in natural populations of Drosophila simulans in Japan
by Yoshitake, Yusaku and Inomata, Nobuyuki and Sano, Mai and Kato, Yasuko and Itoh, Masanobu
Ecology and Evolution, ISSN 2045-7758, 10/2018, Volume 8, Issue 19, pp. 9590 - 9599
Transposable elements not only can change genomic positions and disperse across the gene pool, but also can jump to another species through horizontal... 
transposon | hybrid dysgenesis | Drosophila | horizontal transmission | P element | HORIZONTAL TRANSFER | LONG-TERM | RECENT INVASION | TRANSPOSABLE ELEMENTS | TRANSFORMED LINES | MOLECULAR ANALYSIS | FULL-SIZE P | EVOLUTIONARY BIOLOGY | M SYSTEM | ECOLOGY | KP ELEMENTS | MELANOGASTER | Gonadal dysgenesis | Hybrid dysgenesis | Populations | Insects | Natural populations | P elements | Gene pool | Genomes | Chromosome 3 | Deoxyribonucleic acid--DNA
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8. Full Text Progressive Mycotic Celiac Artery Aneurysm Associated With Coagulase-Negative Staphylococcal Prosthetic Valve Endocarditis
by Tanaka, Makoto and Kohno, Takashi and Obara, Hideaki and Nakatsuka, Seishi and Nishiyama, Takahiko and Nishiyama, Nobuhiro and Tsuruta, Hikaru and Murata, Mitsushige and Maekawa, Yuichiro and Yoshitake, Akihiro and Sano, Motoaki and Shimizu, Hideyuki and Fukuda, Keiichi
Circulation Journal, ISSN 1346-9843, 2018, Volume 82, Issue 7, pp. 1965 - 1967
TRUNK | CARDIAC & CARDIOVASCULAR SYSTEMS
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9. Full Text Impact of the clinical frailty scale on outcomes after transcatheter aortic valve replacement
by Shimura, Tetsuro and Yamamoto, Masanori and Kano, Seiji and Kagase, Ai and Kodama, Atsuko and Koyama, Yutaka and Tsuchikane, Etsuo and Suzuki, Takahiko and Otsuka, Toshiaki and Kohsaka, Shun and Tada, Norio and Yamanaka, Futoshi and Naganuma, Toru and Araki, Motoharu and Shirai, Shinichi and Watanabe, Yusuke and Hayashida, Kentaro and OCEAN-TAVI Investigators
Circulation, ISSN 0009-7322, 05/2017, Volume 135, Issue 21, pp. 2013 - 2024
BACKGROUND: The semiquantitative Clinical Frailty Scale (CFS) is a simple tool to assess patients' frailty and has been shown to correlate with mortality in... 
Clinical frailty scale | Frailty | Transcatheter aortic valve replacement | OCEAN | clinical frailty scale | MORTALITY | CARDIAC & CARDIOVASCULAR SYSTEMS | STENOSIS | OLDER-ADULTS | ELDERLY-PEOPLE | frailty | HIGH-RISK PATIENTS | MORBIDITY | IMPLANTATION | transcatheter aortic valve replacement | PERIPHERAL VASCULAR DISEASE | REGISTRY | Multivariate Analysis | Predictive Value of Tests | Age Factors | Humans | Male | Aortic Valve Stenosis - mortality | Time Factors | Aged, 80 and over | Female | Registries | Aortic Valve Stenosis - surgery | Transcatheter Aortic Valve Replacement - adverse effects | Severity of Illness Index | Reproducibility of Results | Risk Assessment | Japan | Risk Factors | Aortic Valve Stenosis - physiopathology | Decision Support Techniques | Kaplan-Meier Estimate | Proportional Hazards Models | Logistic Models | Treatment Outcome | Aortic Valve Stenosis - diagnosis | Frail Elderly | Chi-Square Distribution | Geriatric Assessment - methods | Aged | Transcatheter Aortic Valve Replacement - mortality | Observer Variation | Usage | Health aspects | Heart valve replacement
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10. Full Text Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome
by Lee, Yong-Seok and Ehninger, Dan and Zhou, Miou and Oh, Jun-Young and Kang, Minkyung and Kwak, Chuljung and Ryu, Hyun-Hee and Butz, Delana and Araki, Toshiyuki and Cai, Ying and Balaji, J and Sano, Yoshitake and I Nam, Christine and Kim, Hyong Kyu and Kaang, Bong-Kiun and Burger, Corinna and Neel, Benjamin G and Silva, Alcino J
Nature Neuroscience, ISSN 1097-6256, 01/2014, Volume 17, Issue 12, pp. 1736 - 1743
In Noonan syndrome (NS) 30-50% of subjects show cognitive deficits of unknown etiology and with no known treatment. Here, we report that knock-in mice... 
LOVASTATIN | RAS | DYSREGULATION | DISORDERS | MUTATIONS | INHIBITOR | SYNAPTIC PLASTICITY | NEUROSCIENCES | CHOLESTEROL-BIOSYNTHESIS | NEUROFIBROMATOSIS TYPE-1 | CHILDREN | Lovastatin - therapeutic use | Memory Disorders - physiopathology | Lovastatin - pharmacology | Maze Learning - physiology | Learning - drug effects | Humans | Mice, Inbred C57BL | Noonan Syndrome - physiopathology | Rats | Male | Treatment Outcome | Mice, 129 Strain | Random Allocation | Maze Learning - drug effects | Noonan Syndrome - drug therapy | Learning - physiology | Animals | Memory Disorders - drug therapy | Long-Term Potentiation - drug effects | Long-Term Potentiation - physiology | Female | Mice | Disease Models, Animal | Physiological aspects | Care and treatment | Learning disabilities | Memory, Disorders of | Noonan syndrome
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11. Full Text Rubber tail illusion is weakened in Ca2+-dependent activator protein for secretion 2 (Caps2)-knockout mice
by Wada, M and Ide, M and Atsumi, T and Sano, Y and Shinoda, Y and Furuichi, T and Kansaku, K
SCIENTIFIC REPORTS, ISSN 2045-2322, 05/2019, Volume 9, Issue 1, pp. 1 - 9
Body ownership is a fundamental aspect of self-consciousness. Illusion of body ownership is caused by updating body representation through multisensory... 
TOOL-USE | BODY OWNERSHIP | AUTISM | HAND ILLUSION | MULTIDISCIPLINARY SCIENCES | SIGNALS | EXCITATION/INHIBITION | PHENOTYPES | MOUSE MODELS | BALANCE | CAPS2 | Autism | Animal models | Phenotypes | Calcium | Sensory integration | Secretion | Rodents | Information processing | Response rates | Rubber
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12. Full Text Molecular and cellular mechanisms for trapping and activating emotional memories
by Rogerson, Thomas and Jayaprakash, Balaji and Cai, Denise J and Sano, Yoshitake and Lee, Yong-Seok and Zhou, Yu and Bekal, Pallavi and Deisseroth, Karl and Silva, Alcino J
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, p. e0161655
Recent findings suggest that memory allocation to specific neurons (i.e., neuronal allocation) in the amygdala is not random, but rather the transcription... 
CONTRIBUTE | FEAR MEMORY | EXCITABILITY | BEHAVIOR | MULTIDISCIPLINARY SCIENCES | LATERAL AMYGDALA | NEURONS | NEURAL CIRCUITS | ENGRAM | ALLOCATION | EXPRESSION | Animals | Amygdala - metabolism | Cyclic AMP Response Element-Binding Protein - metabolism | Opsins - metabolism | Channelrhodopsins | Male | Mice | Neurons - metabolism | Fear - physiology | Memory - physiology | Binding proteins | Neurons | Analysis | Neurosciences | Amygdala | Memory | Neurobiology | Science | Activation | Unconditioned stimulus | Recruitment | Training | Light | Physiology | Anxiety | Recall | Excitation | Step functions | Departments | Excitability | Cyclic AMP response element-binding protein | Emotions | Fear conditioning | Hypotheses | Brain research | Memory management | Alzheimers disease | Psychiatry
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