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1. Histological spectrum of oligodendroglial tumors: Only a subset shows 1p/19q codeletion
by Santosh, Vani
Neurology India, ISSN 0028-3886, 01/2017, Volume 65, Issue 1, pp. 121 - 122
IN-SITU HYBRIDIZATION | PEDIATRIC OLIGODENDROGLIOMAS | PROGNOSTIC-SIGNIFICANCE | 19Q STATUS | NEUROSCIENCES
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2. Full Text SHH-activated Large cell/Anaplastic medulloblastoma with myogenic differentiation - case report
by Rao, Shilpa and Mohan Uppar, Alok and Santosh, Vani
World Neurosurgery, ISSN 1878-8750, 12/2019
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3. Full Text Genome-wide expression profiling identifies deregulated miRNAs in malignant astrocytoma
by Rao, Soumya A.M and Santosh, Vani and Somasundaram, Kumaravel
Modern Pathology, ISSN 0893-3952, 10/2010, Volume 23, Issue 10, pp. 1404 - 1417
Malignant astrocytoma includes anaplastic astrocytoma (grade III) and glioblastoma (grade IV). Among them, glioblastoma is the most common primary brain tumor... 
MicroRNA | Glioma | Microarray | PAM | Astrocytoma | Glioblastoma | PATHWAYS | CELLS | GLIOBLASTOMA-MULTIFORME | PROLIFERATION | PATHOLOGY | MICRORNA-21 | CANCER | microarray | glioblastoma | astrocytoma | GENE-EXPRESSION | glioma | microRNA | MICROARRAYS | HIGH-GRADE GLIOMA | BRAIN | Astrocytoma - genetics | Immunohistochemistry | Astrocytoma - pathology | Genome-Wide Association Study | MicroRNAs - analysis | Humans | Brain Neoplasms - pathology | Brain Neoplasms - genetics | Biomarkers, Tumor - genetics | Gene Expression Profiling | MicroRNAs - genetics | Reverse Transcriptase Polymerase Chain Reaction
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4. Full Text Expression pattern and prognostic significance of myosin light chain 9 (MYL9): a novel biomarker in glioblastoma
by Kruthika, Banavathy S and Sugur, Harsha and Nandaki, Kanuri and Arimappamagan, Arivazhagan and Paturu, Kondaiah and Santosh, Vani
Journal of Clinical Pathology, ISSN 0021-9746, 10/2019, Volume 72, Issue 10, pp. 677 - 681
AimsTumour recurrence is inevitable in glioblastoma (GBM) and mostly noted in the peritumoural brain zone (PT). In our previous microarray-based study, we... 
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5. Full Text GENE-51. ROLE OF TUMOR ENDOTHELIAL MARKER 8 (TEM8) IN PRIMARY AND RECURRENT GLIOBLASTOMA
by Kundu, Paramita and Jain, Ruchi and Arimappamagan, Arivazhagan and Santosh, Vani and Kondaiah, Paturu
Neuro-Oncology, ISSN 1522-8517, 11/2019, Volume 21, Issue Supplement_6, pp. vi108 - vi109
Abstract Glioblastoma (GBM) is the most common primary malignant tumor of the adult central nervous system. It is highly invasive and almost inevitably recurs;... 
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6. MGMT promoter methylation in glioblastoma
by Santosh, Vani and Sravya, P
Neurology India, ISSN 0028-3886, 07/2018, Volume 66, Issue 4, pp. 1115 - 1116
PHASE-3 TRIAL | RADIOTHERAPY | NEUROSCIENCES | CHEMOTHERAPY | TEMOZOLOMIDE
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7. Full Text miR-219-5p Inhibits Receptor Tyrosine Kinase Pathway by Targeting EGFR in Glioblastoma
by Rao, Soumya Alige Mahabala and Arimappamagan, Arivazhagan and Pandey, Paritosh and Santosh, Vani and Hegde, Alangar Sathyaranjandas and Chandramouli, Bangalore Ashwathnarayanara and Somasundaram, Kumaravel
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e63164
Glioblastoma is one of the common types of primary brain tumors with a median survival of 12-15 months. The receptor tyrosine kinase (RTK) pathway is known to... 
MULTIDISCIPLINARY SCIENCES | MICRORNAS | Mutagenesis, Site-Directed | Humans | 3' Untranslated Regions - genetics | MicroRNAs - metabolism | DNA Primers - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Receptor, Epidermal Growth Factor - metabolism | Receptor Protein-Tyrosine Kinases - genetics | Microarray Analysis | Cell Line, Tumor | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Glioblastoma - metabolism | Signal Transduction - physiology | Colony-Forming Units Assay | Real-Time Polymerase Chain Reaction | Tyrosine | Phenols | Genetic aspects | MicroRNA | Glioblastoma multiforme | Brain tumors | Brain | Biotechnology | Deregulation | Brain cancer | Glioblastoma | Mental health | Genomes | Biology | Neurosurgery | Kinases | Cancer therapies | Proteins | Pathways | Glioma cells | Protein-tyrosine kinase receptors | Inhibition | Protein-tyrosine kinase | Medical research | Epidermal growth factor receptors | MiRNA | MAP kinase | Patients | 1-Phosphatidylinositol 3-kinase | Brain research | 3' Untranslated regions | MicroRNAs | Medical prognosis | Cell lines | Tumor suppressor genes | Mutation | Cell migration | Apoptosis | Tumors
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8. Full Text Fourth ventricular ependymoma with a distant intraventricular metastasis: Report of a rare case
by Ambekar, Sudheer and Ranjan, Manish and Somanna, Sampath and Prasad, Chandrajit and Santosh, Vani
Journal of Neurosciences in Rural Practice, ISSN 0976-3147, 12/2013, Volume 4, Issue S 01, pp. S121 - S124
ABSTRACT Ependymoma is one of the uncommon tumors of the central nervous system (CNS) in the adult age group. These tumors have a distinct propensity for... 
Case Report | ependymoma | metastasis | Anaplasia | cerebrospinal fluid | Case studies | Care and treatment | Diagnosis | Metastasis | Research | Gliomas | Spinal cord | Medical imaging | Nuclear magnetic resonance--NMR | Multivariate analysis | Tumors | Aggressiveness | Cerebrospinal fluid | Ependymoma
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9. Full Text PI3 kinase pathway regulated miRNome in glioblastoma: Identification of miR-326 as a tumour suppressor miRNA
by Nawaz, Zahid and Patil, Vikas and Paul, Yashna and Hegde, Alangar S and Arivazhagan, Arimappamagan and Santosh, Vani and Somasundaram, Kumaravel
Molecular Cancer, ISSN 1476-4598, 11/2016, Volume 15, Issue 1, p. 74
Background: Glioblastomas (GBM) continue to remain one of the most dreaded tumours that are highly infiltrative in nature and easily preclude comprehensive... 
LY294002 | Growth suppression and RNA sequencing | MiR-326 | Glioblastoma | ARRB1 | MiRNome | PI3 kinase pathway | CELLS | PHOSPHORYLATION | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | miR-326 | CANCER | MICRORNA CONTROL | BRAIN-TUMORS | miRNome | BIOGENESIS | ONCOLOGY | LEUKEMIA | PROMOTER | EXPRESSION | Computational Biology - methods | Signal Transduction | Humans | Gene Expression Regulation, Neoplastic | Transcriptome | Brain Neoplasms - genetics | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Brain Neoplasms - metabolism | Phosphatidylinositol 3-Kinases - genetics | Glioblastoma - genetics | RNA Interference | beta-Arrestin 1 - genetics | Cell Transformation, Neoplastic - genetics | Cell Line, Tumor | Glioblastoma - metabolism | MicroRNAs - genetics | Genes, Tumor Suppressor | Gene Ontology | Cluster Analysis | MicroRNA | Physiological aspects | Development and progression | Tumor suppressor genes | Genetic aspects | Research | Glioblastoma multiforme
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10. Full Text Serum biomarkers identification by iTRAQ and verification by MRM: S100A8/S100A9 levels predict tumor-stroma involvement and prognosis in Glioblastoma
by Arora, A and Patil, V and Kundu, P and Kondaiah, P and Hegde, AS and Arivazhagan, A and Santosh, V and Pal, D and Somasundaram, K
SCIENTIFIC REPORTS, ISSN 2045-2322, 02/2019, Volume 9, Issue 1, pp. 2749 - 12
Despite advances in biology and treatment modalities, the prognosis of glioblastoma (GBM) remains poor. Serum reflects disease macroenvironment and thus... 
SURVIVAL | PLASMA-LEVELS | MARKER | PURITY | MULTIDISCIPLINARY SCIENCES | TISSUE | S100 PROTEIN FAMILY | S100A8/A9 | SUPPRESSOR-CELLS | YKL-40 | EXPRESSION | Prognosis | Transcription | Medical prognosis | Glioma cells | Glioblastoma | Stroma | Cell lineage | Quantitation | Cell migration | Enzyme-linked immunosorbent assay | Cell adhesion & migration
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11. Full Text Comparative evaluation of cerebral gliomas using rCBV measurements during sequential acquisition of T1-perfusion and T2-perfusion MRI
by Saini, J and Gupta, RK and Kumar, M and Singh, A and Saha, I and Santosh, V and Beniwal, M and Kandavel, T and Van Cauteren, M
PLOS ONE, ISSN 1932-6203, 04/2019, Volume 14, Issue 4, p. e0215400
Objective To assess the inter-technique agreement of relative cerebral blood volume (rCBV) measurements obtained using T1-and T2*-perfusion MRI on 3T scanner... 
PERFUSION MRI | CONTRAST-ENHANCED MRI | TUMOR RECURRENCE | PERMEABILITY | GRADE GLIOMAS | MULTIDISCIPLINARY SCIENCES | INPUT FUNCTION | RECURRENT GLIOBLASTOMA | BLOOD-VOLUME | DIAGNOSTIC-ACCURACY | BRAIN GLIOMAS | Medicine, Experimental | Medical research | Magnetic resonance imaging | Comparative analysis | Gliomas | Brain tumors | Research | Analysis | Cerebral circulation | Brain | Neurosciences | Brain cancer | Correlation coefficients | Medical diagnosis | Hemorrhage | Blood | Accuracy | Blood volume | Cerebral blood flow | Qualitative analysis | Lesions | Quantitative analysis | Correlation coefficient | Evaluation | Statistical analysis | Medical imaging | Observers | Permeability | Glioma | Perfusion | Diagnostic systems | Hemodynamics | Gene mapping | Tumors
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12. Full Text Transcriptome profiling reveals PDZ binding kinase as a novel biomarker in peritumoral brain zone of glioblastoma
by Kruthika, Banavathy S and Kruthika, Banavathy S and Jain, Ruchi and Jain, Ruchi and Arivazhagan, A and Arivazhagan, A and Bharath, R D and Bharath, R D and Yasha, T C and Yasha, T C and Kondaiah, Paturu and Kondaiah, Paturu and Santosh, Vani and Santosh, Vani
Journal of Neuro-Oncology, ISSN 0167-594X, 1/2019, Volume 141, Issue 2, pp. 315 - 325
Peritumoural brain zone (PT) of glioblastoma (GBM) is the area where tumour recurrence is often observed. We aimed to identify differentially regulated genes... 
Neurology | Recurrence | GBM | Medicine & Public Health | PBK | Oncology | Peritumoural brain zone | Gene expression profile | INITIATING CELLS | SURVIVAL | ANGIOGENESIS | PHENOTYPE | SUPPRESSION | CLINICAL NEUROLOGY | GENE | ONCOLOGY | POOR-PROGNOSIS | PROSTATE-CANCER | EXPRESSION | PBK/TOPK | Cell proliferation | DNA microarrays | Glioblastoma | Chemoresistance | Data processing | Temozolomide | Gene expression | Kinases | Cell migration | Tumors
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13. Full Text A simple algorithmic approach using histology and immunohistochemistry for the current classification of adult diffuse glioma in a resource-limited set-up
by Rajeswarie, R T and Rao, Shilpa and Nandeesh, Bevinahalli N and Yasha, T Chickabasaviah and Santosh, Vani
Journal of Clinical Pathology, ISSN 0021-9746, 04/2018, Volume 71, Issue 4, pp. 323 - 329
AimsThe WHO 2016 classification of diffuse gliomas combines histological and molecular parameters for diagnosis. However, in view of cost constraints for... 
resource constraint | integrated diagnosis | algorithmic approach | diffuse glioma | ASTROCYTOMA | TERT PROMOTER MUTATIONS | OLIGODENDROGLIOMA | PROGNOSTIC-FACTORS | ATRX | PATHOLOGY | IDH | TUMORS | LOW-GRADE | Isocitrate Dehydrogenase - biosynthesis | Glioma - classification | Biomarkers, Tumor - analysis | Humans | Middle Aged | Brain Neoplasms - pathology | Male | Immunohistochemistry - methods | Young Adult | Algorithms | X-linked Nuclear Protein - biosynthesis | Brain Neoplasms - classification | Glioma - pathology | Isocitrate Dehydrogenase - analysis | Adult | Female | Aged | X-linked Nuclear Protein - analysis | Automation | Laboratories | Neuropathology | Medical prognosis | Brain cancer | Classification | Nervous system | Histology | Mutation | Medical diagnosis | Tumors
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14. Full Text Prognostic significance of histomolecular subgroups of adult anaplastic (WHO Grade III) gliomas: applying the ‘integrated’ diagnosis approach
by Rajmohan, K S and Sugur, Harsha S and Shwetha, S D and Ramesh, Arvind and Thennarasu, Kandavel and Pandey, Paritosh and Arivazhagan, Arimappamagan and Santosh, Vani
Journal of Clinical Pathology, ISSN 0021-9746, 08/2016, Volume 69, Issue 8, pp. 686 - 694
AimsAnaplastic gliomas (AGs; WHO Grade III) include anaplastic astrocytoma (AA), anaplastic oligodendroglioma (AO) and anaplastic oligoastrocytoma (AOA) and... 
SURVIVAL | IDH1 MUTATIONS | MGMT PROMOTER METHYLATION | MALIGNANT GLIOMAS | CLASSIFICATION | OLIGODENDROGLIAL TUMORS | PATHOLOGY | MOLECULAR DIAGNOSTICS | CHEMOTHERAPY | BRAIN-TUMORS | 1P/19Q LOSS | Prognosis | Humans | Middle Aged | Oligodendroglioma - diagnosis | Brain Neoplasms - pathology | Male | X-linked Nuclear Protein | Brain Neoplasms - metabolism | Young Adult | Astrocytoma - pathology | DNA Repair Enzymes - metabolism | Oligodendroglioma - metabolism | Adult | Female | Brain Neoplasms - mortality | Astrocytoma - diagnosis | Astrocytoma - mortality | Astrocytoma - metabolism | Oligodendroglioma - mortality | Promoter Regions, Genetic | Tumor Suppressor Proteins - metabolism | DNA Modification Methylases - metabolism | Brain Neoplasms - diagnosis | Nuclear Proteins - metabolism | Survival Rate | DNA Helicases - metabolism | Oligodendroglioma - pathology | Isocitrate Dehydrogenase - metabolism
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15. Full Text High frequency of H3K27M immunopositivity in adult thalamic glioblastoma
by Rao, Shilpa and Kanuri, Nandaki N and Nimbalkar, Vidya and Arivazhagan, Arimappamagan and Santosh, Vani
Neuropathology, ISSN 0919-6544, 04/2019, Volume 39, Issue 2, pp. 78 - 84
Adult thalamic glioblastomas (GBM) are uncommon tumors with limited available molecular data. One of the reported molecular alterations in these tumors is the... 
GBM | thalamic | adult | immunopositivity | H3K27M | MOLECULAR SUBGROUPS | MUTATIONS | PATHOLOGY | BRAIN-STEM GLIOMAS | NEUROSCIENCES | CLINICAL NEUROLOGY | Adults | Biological products | Tumor proteins | Methylation | Analysis | Immunohistochemistry | RNA-directed DNA polymerase | Telomerase reverse transcriptase | Epidermal growth factor receptors | p53 Protein | Methylguanine | Glioblastoma | Thalassemia | O6-methylguanine-DNA methyltransferase | Epidermal growth factor | Older people | DNA methylation | DNA methyltransferase | Thalamus | Decompression | Mutation | Isocitrate dehydrogenase | Telomerase | Tumors
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16. Full Text Cbx7 is epigenetically silenced in glioblastoma and inhibits cell migration by targeting YAP/TAZ-dependent transcription
by Nawaz, Zahid and Patil, Vikas and Arora, Anjali and Hegde, Alangar S and Arivazhagan, Arimappamagan and Santosh, Vani and Somasundaram, Kumaravel
Scientific Reports, ISSN 2045-2322, 06/2016, Volume 6, Issue 1, p. 27753
Glioblastomas (GBM) are the most malignant form of astrocytomas which are difficult to treat and portend a grave clinical course and poor prognosis. In this... 
CHROMOBOX PROTEIN | POLYCOMB GROUP PROTEINS | TISSUE GROWTH-FACTOR | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | MOLECULAR PATHOLOGY | HIPPO PATHWAY | TUMOR-SUPPRESSOR | PROLIFERATION | EXPRESSION | HUMAN CANCER
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