Science, ISSN 0036-8075, 12/2018, Volume 362, Issue 6420, pp. 1264 - 1264
To broaden our understanding of human neurodevelopment, we profiled transcriptomic and epigenomic landscapes across brain regions and/or cell types for the...
READ ALIGNMENT | EXPRESSION ANALYSIS | DE-NOVO MUTATIONS | DNA METHYLATION | MENTAL-RETARDATION | TRANSCRIPTOME | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | ARCHITECTURE | SINGLE-CELL ANALYSIS | ASSOCIATION | Neurogenesis - genetics | Mental Disorders - genetics | Brain - embryology | Epigenomics | Gene Expression Regulation, Developmental | Epigenesis, Genetic | Humans | Transcriptome | Brain - growth & development | Gene Regulatory Networks | Nervous System Diseases - genetics | Single-Cell Analysis | Brain | Genetic aspects | Health aspects | Genomics | Methods | Adolescence | Regulations | Transcription | Mental disorders | Genes | Gene regulation | Modules | Spatial discrimination | Disorders | Regional development | Cognition | Neurodevelopmental disorders | Convergence | Embryogenesis | Etiology | Oligodendrocytes | DNA methylation | Children | Adolescents | Deoxyribonucleic acid--DNA | Genomic analysis | Fetuses | Regional analysis | Cortex | Health risks | Gene expression | Embryonic growth stage | Myelination | Disruption | Methylation | Human behavior | Dendritic structure
READ ALIGNMENT | EXPRESSION ANALYSIS | DE-NOVO MUTATIONS | DNA METHYLATION | MENTAL-RETARDATION | TRANSCRIPTOME | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | ARCHITECTURE | SINGLE-CELL ANALYSIS | ASSOCIATION | Neurogenesis - genetics | Mental Disorders - genetics | Brain - embryology | Epigenomics | Gene Expression Regulation, Developmental | Epigenesis, Genetic | Humans | Transcriptome | Brain - growth & development | Gene Regulatory Networks | Nervous System Diseases - genetics | Single-Cell Analysis | Brain | Genetic aspects | Health aspects | Genomics | Methods | Adolescence | Regulations | Transcription | Mental disorders | Genes | Gene regulation | Modules | Spatial discrimination | Disorders | Regional development | Cognition | Neurodevelopmental disorders | Convergence | Embryogenesis | Etiology | Oligodendrocytes | DNA methylation | Children | Adolescents | Deoxyribonucleic acid--DNA | Genomic analysis | Fetuses | Regional analysis | Cortex | Health risks | Gene expression | Embryonic growth stage | Myelination | Disruption | Methylation | Human behavior | Dendritic structure
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7459, pp. 471 - 475
Most great ape genetic variation remains uncharacterized(1,2); however, its study is critical for understanding population history(3-6), recombination(7),...
CHIMPANZEE GENOME | HUMAN GENOME | EVOLUTION | MULTIDISCIPLINARY SCIENCES | SEQUENCE | PATTERNS | SELECTION | DECLINE | Gene Flow - genetics | Genetics, Population | Humans | Africa | Genome - genetics | Pan troglodytes - genetics | Pan paniscus - classification | Phylogeny | Hominidae - genetics | Pan paniscus - genetics | Asia, Southeastern | Genetic Variation | Gorilla gorilla - genetics | Animals | Population Density | Polymorphism, Single Nucleotide - genetics | Inbreeding | Pan troglodytes - classification | Gorilla gorilla - classification | Animals, Wild - genetics | Hominidae - classification | Animals, Zoo - genetics | Evolution, Molecular | Apes | Genetic aspects | Research | Genetic variation | Population genetics | Biological diversity | Trees | Genealogy | Genomics | Evolution | Population | Principal components analysis | Genomes | Genetic diversity | Monkeys & apes | Evolució (Biologia)
CHIMPANZEE GENOME | HUMAN GENOME | EVOLUTION | MULTIDISCIPLINARY SCIENCES | SEQUENCE | PATTERNS | SELECTION | DECLINE | Gene Flow - genetics | Genetics, Population | Humans | Africa | Genome - genetics | Pan troglodytes - genetics | Pan paniscus - classification | Phylogeny | Hominidae - genetics | Pan paniscus - genetics | Asia, Southeastern | Genetic Variation | Gorilla gorilla - genetics | Animals | Population Density | Polymorphism, Single Nucleotide - genetics | Inbreeding | Pan troglodytes - classification | Gorilla gorilla - classification | Animals, Wild - genetics | Hominidae - classification | Animals, Zoo - genetics | Evolution, Molecular | Apes | Genetic aspects | Research | Genetic variation | Population genetics | Biological diversity | Trees | Genealogy | Genomics | Evolution | Population | Principal components analysis | Genomes | Genetic diversity | Monkeys & apes | Evolució (Biologia)
Journal Article
3.
Full Text
Derived immune and ancestral pigmentation alleles in a 7,000-year-old Mesolithic European
Nature, ISSN 0028-0836, 2014, Volume 507, Issue 7491, pp. 225 - 228
Ancient genomic sequences have started to reveal the origin and the demographic impact of farmers from the Neolithic period spreading into Europe. The adoption...
POPULATION | EVOLUTION | GENETICS | DNA | MULTIDISCIPLINARY SCIENCES | SEQUENCE | GENES | EYE COLOR | HUNTER-GATHERERS | GENOME | INSIGHTS | History, Ancient | European Continental Ancestry Group - genetics | Genomics | Humans | Male | Eye Color - genetics | Genome, Human - genetics | Fossils | Skin Pigmentation - genetics | Biological Evolution | Spain - ethnology | Pigmentation - genetics | Agriculture - history | Alleles | Caves | Polymorphism, Single Nucleotide - genetics | Skeleton | Lactose Intolerance - genetics | Immunity - genetics | Principal Component Analysis | Allelomorphism | Skin color | Physiological aspects | Genetic aspects | Research | Nucleotide sequencing | DNA sequencing | Haplotypes | Confidence intervals | Genealogy | Genes | Principal components analysis | Genomes | Mitochondrial DNA | Evolution & development | Deoxyribonucleic acid--DNA | Genealogia | Color de la pell humana | Genètica | Immunogenètica | Al·lel | Fòssils
POPULATION | EVOLUTION | GENETICS | DNA | MULTIDISCIPLINARY SCIENCES | SEQUENCE | GENES | EYE COLOR | HUNTER-GATHERERS | GENOME | INSIGHTS | History, Ancient | European Continental Ancestry Group - genetics | Genomics | Humans | Male | Eye Color - genetics | Genome, Human - genetics | Fossils | Skin Pigmentation - genetics | Biological Evolution | Spain - ethnology | Pigmentation - genetics | Agriculture - history | Alleles | Caves | Polymorphism, Single Nucleotide - genetics | Skeleton | Lactose Intolerance - genetics | Immunity - genetics | Principal Component Analysis | Allelomorphism | Skin color | Physiological aspects | Genetic aspects | Research | Nucleotide sequencing | DNA sequencing | Haplotypes | Confidence intervals | Genealogy | Genes | Principal components analysis | Genomes | Mitochondrial DNA | Evolution & development | Deoxyribonucleic acid--DNA | Genealogia | Color de la pell humana | Genètica | Immunogenètica | Al·lel | Fòssils
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e56075
Composts are the products obtained after the aerobic degradation of different types of organic matter waste and can be used as substrates or substrate/soil...
TRANSCRIPTION FACTORS | STRESS RESPONSES | SALICYLIC-ACID | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | CAMALEXIN BIOSYNTHESIS | ABSCISIC-ACID | INDUCED SYSTEMIC RESISTANCE | PATTERN-RECOGNITION RECEPTORS | DISEASE RESISTANCE | HYPERSENSITIVE RESPONSE | Biomarkers - metabolism | Arabidopsis Proteins - genetics | Oligonucleotide Array Sequence Analysis | Plant Diseases - immunology | Plant Leaves | Immunity, Innate - genetics | Arabidopsis - immunology | Fluorescence | Plant Diseases - microbiology | Gene Expression Profiling | Chlorophyll - metabolism | Botrytis - physiology | Arabidopsis - genetics | Arabidopsis - microbiology | Gene Expression Regulation, Plant | Soil | Plant Diseases - genetics | Olea - chemistry | Arabidopsis thaliana | DNA microarrays | Gene expression | Genes | Enrichment | Oxidative stress | Organic matter | Transcription factors | Aerobic conditions | Pathogenesis | Genomics | Soil amendment | Biosynthesis | Fruit trees | Proteins | Leaves | Signal transduction | Inoculation | Abscisic acid | Stress response | Biodegradation | Plants (botany) | Cultivation | Abiotic stress | Water temperature | Perlite | Substrates | Plant diseases | Composting | Composts | Foliar diseases | Compost | Arabis | Factors de transcripció | Desenvolupament de les plantes | Regulació genètica | Plant development | Àrabis | Genetic regulation
TRANSCRIPTION FACTORS | STRESS RESPONSES | SALICYLIC-ACID | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | CAMALEXIN BIOSYNTHESIS | ABSCISIC-ACID | INDUCED SYSTEMIC RESISTANCE | PATTERN-RECOGNITION RECEPTORS | DISEASE RESISTANCE | HYPERSENSITIVE RESPONSE | Biomarkers - metabolism | Arabidopsis Proteins - genetics | Oligonucleotide Array Sequence Analysis | Plant Diseases - immunology | Plant Leaves | Immunity, Innate - genetics | Arabidopsis - immunology | Fluorescence | Plant Diseases - microbiology | Gene Expression Profiling | Chlorophyll - metabolism | Botrytis - physiology | Arabidopsis - genetics | Arabidopsis - microbiology | Gene Expression Regulation, Plant | Soil | Plant Diseases - genetics | Olea - chemistry | Arabidopsis thaliana | DNA microarrays | Gene expression | Genes | Enrichment | Oxidative stress | Organic matter | Transcription factors | Aerobic conditions | Pathogenesis | Genomics | Soil amendment | Biosynthesis | Fruit trees | Proteins | Leaves | Signal transduction | Inoculation | Abscisic acid | Stress response | Biodegradation | Plants (botany) | Cultivation | Abiotic stress | Water temperature | Perlite | Substrates | Plant diseases | Composting | Composts | Foliar diseases | Compost | Arabis | Factors de transcripció | Desenvolupament de les plantes | Regulació genètica | Plant development | Àrabis | Genetic regulation
Journal Article
Genome Biology, ISSN 1474-7596, 04/2019, Volume 20, Issue 1, pp. 77 - 15
BackgroundPopulation demography and gene flow among African groups, as well as the putative archaic introgression of ancient hominins, have been poorly...
Genome diversity | Whole-genome sequences | Archaic introgression | Human population genetics | Africa | MUTATION-RATE | DEMOGRAPHIC HISTORY | JEBEL IRHOUD | NEANDERTHAL | ADMIXTURE | Y-CHROMOSOME | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DNA | ADAPTATION | GENETICS & HEREDITY | PYGMY HUNTER-GATHERERS | EVOLUTIONARY HISTORY | Rainforests | Genomic analysis | Demography | Nucleotide sequence | Genomes | Mitochondrial DNA | Genetic diversity | Multiculturalism & pluralism | Hominids | Bantu languages | Gene flow | Population | Bioinformatics | Deoxyribonucleic acid--DNA
Genome diversity | Whole-genome sequences | Archaic introgression | Human population genetics | Africa | MUTATION-RATE | DEMOGRAPHIC HISTORY | JEBEL IRHOUD | NEANDERTHAL | ADMIXTURE | Y-CHROMOSOME | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DNA | ADAPTATION | GENETICS & HEREDITY | PYGMY HUNTER-GATHERERS | EVOLUTIONARY HISTORY | Rainforests | Genomic analysis | Demography | Nucleotide sequence | Genomes | Mitochondrial DNA | Genetic diversity | Multiculturalism & pluralism | Hominids | Bantu languages | Gene flow | Population | Bioinformatics | Deoxyribonucleic acid--DNA
Journal Article
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2018, Volume 8
Journal Article
Molecular medicine (Cambridge, Mass.), ISSN 1076-1551, 2011, Volume 17, Issue 9-10, pp. 1107 - 1118
Lipid rafts are cholesterol- and sphingomyelin-enriched microdomains that provide a highly saturated and viscous physicochemical microenvironment to promote...
MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | LEWY BODY DISEASE | PHOSPHOLIPASE A | ALPHA-SYNUCLEIN | SUBSTANTIA-NIGRA | CELL BIOLOGY | MEMBRANE MICRODOMAINS | DOCOSAHEXAENOIC ACID | POLYUNSATURATED FATTY-ACIDS | HUMAN BRAIN CORTEX | Sulfoglycosphingolipids - analysis | Frontal Lobe - metabolism | Membrane Microdomains - metabolism | Phosphatidylinositols - analysis | Humans | Male | Chromatography, Gas | Fatty Acids - classification | Lipids - chemistry | Autopsy | Arachidonic Acid - analysis | Female | Lipids - classification | Parkinson Disease - metabolism | Superoxide Dismutase - metabolism | Parkinson Disease - pathology | Fatty Acids - analysis | Membrane Microdomains - chemistry | Plasmalogens - analysis | Frontal Lobe - chemistry | Phosphatidylserines - analysis | Cerebrosides - analysis | Blotting, Western | Docosahexaenoic Acids - analysis | Aged | Lipids - analysis | Superoxide Dismutase-1
MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | LEWY BODY DISEASE | PHOSPHOLIPASE A | ALPHA-SYNUCLEIN | SUBSTANTIA-NIGRA | CELL BIOLOGY | MEMBRANE MICRODOMAINS | DOCOSAHEXAENOIC ACID | POLYUNSATURATED FATTY-ACIDS | HUMAN BRAIN CORTEX | Sulfoglycosphingolipids - analysis | Frontal Lobe - metabolism | Membrane Microdomains - metabolism | Phosphatidylinositols - analysis | Humans | Male | Chromatography, Gas | Fatty Acids - classification | Lipids - chemistry | Autopsy | Arachidonic Acid - analysis | Female | Lipids - classification | Parkinson Disease - metabolism | Superoxide Dismutase - metabolism | Parkinson Disease - pathology | Fatty Acids - analysis | Membrane Microdomains - chemistry | Plasmalogens - analysis | Frontal Lobe - chemistry | Phosphatidylserines - analysis | Cerebrosides - analysis | Blotting, Western | Docosahexaenoic Acids - analysis | Aged | Lipids - analysis | Superoxide Dismutase-1
Journal Article
Cell, ISSN 0092-8674, 07/2017, Volume 170, Issue 2, pp. 226 - 247
The nervous system—in particular, the brain and its cognitive abilities—is among humans’ most distinctive and impressive attributes. How the nervous system has...
DNA METHYLATION PATTERNS | HUMAN BRAIN | WHITE-MATTER | ACCELERATED EVOLUTION | NONCODING SEQUENCES | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | GREAT APES | ARCUATE FASCICULUS | COPY NUMBER VARIATION | CEREBRAL-CORTEX | CELL BIOLOGY | Nervous System - cytology | Brain - cytology | Brain - anatomy & histology | Species Specificity | Primates - physiology | Gene Expression Regulation | Brain - physiology | Nerve Tissue Proteins - genetics | Nervous System - anatomy & histology | Biological Evolution | Primates - genetics | Animals | Language | Nervous System - growth & development | Nervous System Physiological Phenomena | Mutation | Medical colleges | Neurosciences | Neural circuitry | Evolutionary biology | Neurons | Analysis | Human evolution
DNA METHYLATION PATTERNS | HUMAN BRAIN | WHITE-MATTER | ACCELERATED EVOLUTION | NONCODING SEQUENCES | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | GREAT APES | ARCUATE FASCICULUS | COPY NUMBER VARIATION | CEREBRAL-CORTEX | CELL BIOLOGY | Nervous System - cytology | Brain - cytology | Brain - anatomy & histology | Species Specificity | Primates - physiology | Gene Expression Regulation | Brain - physiology | Nerve Tissue Proteins - genetics | Nervous System - anatomy & histology | Biological Evolution | Primates - genetics | Animals | Language | Nervous System - growth & development | Nervous System Physiological Phenomena | Mutation | Medical colleges | Neurosciences | Neural circuitry | Evolutionary biology | Neurons | Analysis | Human evolution
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 3472 - 13
Human herpesviruses 6-A and -B (HHV-6A, HHV-6B) are ubiquitous in human populations worldwide. These viruses have been associated with several diseases such as...
HUMAN-HERPESVIRUS-6 | DNA-SEQUENCES | MULTIPLE-SCLEROSIS | HUMAN-HERPESVIRUS 6 | CODING CONTENT | MULTIDISCIPLINARY SCIENCES | HUMAN CYTOMEGALOVIRUS | VIRAL GENOME | INFECTION | STEM-CELL TRANSPLANTATION | EPSTEIN-BARR-VIRUS | Genetic Variation | Geography | Cell Line | Roseolovirus Infections - epidemiology | Virus Integration - genetics | Herpesvirus 6, Human - pathogenicity | Roseolovirus Infections - genetics | Humans | Phylogeography | Roseolovirus Infections - virology | Herpesvirus 6, Human - genetics | DNA, Viral - genetics | Encephalitis | Multiple sclerosis | Recombination | Nucleotide sequence | Positive selection | Lymphoblastoid cell lines | Genomes | Genetic diversity | Phylogeny | Lymphoma | Natural selection | Evolution | Deoxyribonucleic acid--DNA | Phylogenetics | Genome informatics | Population genetics | HHV-6
HUMAN-HERPESVIRUS-6 | DNA-SEQUENCES | MULTIPLE-SCLEROSIS | HUMAN-HERPESVIRUS 6 | CODING CONTENT | MULTIDISCIPLINARY SCIENCES | HUMAN CYTOMEGALOVIRUS | VIRAL GENOME | INFECTION | STEM-CELL TRANSPLANTATION | EPSTEIN-BARR-VIRUS | Genetic Variation | Geography | Cell Line | Roseolovirus Infections - epidemiology | Virus Integration - genetics | Herpesvirus 6, Human - pathogenicity | Roseolovirus Infections - genetics | Humans | Phylogeography | Roseolovirus Infections - virology | Herpesvirus 6, Human - genetics | DNA, Viral - genetics | Encephalitis | Multiple sclerosis | Recombination | Nucleotide sequence | Positive selection | Lymphoblastoid cell lines | Genomes | Genetic diversity | Phylogeny | Lymphoma | Natural selection | Evolution | Deoxyribonucleic acid--DNA | Phylogenetics | Genome informatics | Population genetics | HHV-6
Journal Article