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Gut, ISSN 0017-5749, 05/2017, Volume 66, Issue 5, pp. 813 - 822
Journal Article
PLOS BIOLOGY, ISSN 1544-9173, 04/2014, Volume 12, Issue 4, p. e1001833
How the microbiota affects health and disease is a crucial question. In mice, gut Clostridium bacteria are potent inducers of colonic interleukin... 
COEXPRESSION | IFN-GAMMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOLOGY | TREG CELLS | FAECALIBACTERIUM-PRAUSNITZII | MICROBIOTA | MECHANISMS | INDUCTION | INTERLEUKIN-10 | FOXP3(+) | EXPRESSION | Life Sciences | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2016, Volume 11, Issue 2, pp. e0148095 - e0148095
CD70 is a costimulatory molecule member of the Tumor Necrosis Factor family that is expressed on activated immune cells. Its ectopic expression has been... 
MIGRATION | METASTATIC MELANOMA | CELLS | IMMUNITY | INVASION | INHIBITION | GTPASES | MULTIDISCIPLINARY SCIENCES | CD70 EXPRESSION | BRAF | CANCER | Transcription, Genetic - drug effects | Gene Silencing - drug effects | Humans | Melanoma - enzymology | rhoA GTP-Binding Protein - metabolism | Melanoma - pathology | Sulfonamides - pharmacology | MAP Kinase Signaling System - drug effects | Sulfonamides - therapeutic use | Melanoma - genetics | Melanoma - drug therapy | CD27 Ligand - metabolism | Skin Neoplasms | Cell Line, Tumor | Indoles - pharmacology | Indoles - therapeutic use | Cell Membrane - metabolism | Cell Proliferation - drug effects | Cell Membrane - drug effects | Proto-Oncogene Proteins B-raf - metabolism | Vemurafenib | Complications and side effects | Prognosis | Melanoma | Physiological aspects | Genetic aspects | Dosage and administration | Cellular signal transduction | Research | Drug therapy | Biotechnology | Transcription | Gene regulation | Cytotoxicity | Metastasis | CD70 antigen | Kinases | Metastases | Cell growth | Pathways | Lymphocytes | Bioindicators | Killing | Medical research | Kidneys | Tumor cells | MAP kinase | RhoA protein | Immune systems | Studies | Protein kinase | Cell lines | Biomarkers | Mutation | Clear cell-type renal cell carcinoma | Cancer | Apoptosis | Kidney transplantation | Tumors | Index Medicus
Journal Article
PLoS Biology, ISSN 1544-9173, 04/2014, Volume 12, Issue 4
  How the microbiota affects health and disease is a crucial question. In mice, gut Clostridium bacteria are potent inducers of colonic interleukin... 
Inflammatory bowel disease | Cytokines | T cell receptors | Colon | Immune system
Journal Article
Gastroenterology, ISSN 0016-5085, 10/2018, Volume 155, Issue 4, p. 1205
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1053/j.gastro.2018.06.078... 
Inflammatory bowel diseases | Analysis
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2010, Volume 5, Issue 2, pp. e9043 - e9043
Background: Suboptimal activation of T lymphocytes by melanoma cells is often due to the defective expression of class I major histocompatibility antigens... 
INHIBITION | IMMUNOTHERAPY | BIOLOGY | TUMOR-CELLS | ANTITUMOR IMMUNITY | INDUCTION | EXPRESSION | CANCER | PEPTIDE | GERANYLGERANYLTRANSFERASE-I | LYMPHOCYTES | Leukocytes, Mononuclear - metabolism | Coculture Techniques | Humans | Histocompatibility Antigens Class I - metabolism | Flow Cytometry | Melanoma, Experimental - immunology | Vaccination - methods | T-Lymphocytes - metabolism | Leukocytes, Mononuclear - immunology | Female | Benzamides - pharmacology | B7-2 Antigen - immunology | Melanoma - metabolism | Cytokines - metabolism | Jurkat Cells | Mice, Inbred C57BL | Histocompatibility Antigens Class I - immunology | Melanoma, Experimental - pathology | Melanoma - pathology | Blotting, Western | Up-Regulation - drug effects | B7-2 Antigen - metabolism | Animals | Melanoma - immunology | Cell Line, Tumor | Leukocytes, Mononuclear - cytology | T-Lymphocytes - immunology | Mice | Cytotoxicity, Immunologic - immunology | Interferon-gamma - pharmacology | Cell proliferation | Cell culture | Animal models | CD86 antigen | CD8 antigen | Vaccination | Effector cells | Clinical trials | Cytotoxicity | Leukocytes (mononuclear) | Stimulation | Lymphocytes T | Activation | Metastasis | Metastases | Proteins | T-cell receptor | CD69 antigen | Cell activation | Lymphocytes | Immunotherapy | Cell cycle | Pretreatment | Antigens | Enzymes | Immunization | Immune response | Cytokines | Secretion | Tumor cells | Melanoma | Implantation | T cell receptors | Pharmacology | Costimulator | Immune systems | Major histocompatibility complex | Immunogenicity | γ-Interferon | Cell lines | Histocompatibility antigen HLA | Human behavior | Histocompatibility | Cancer | Apoptosis | Index Medicus | Life Sciences | Biochemistry, Molecular Biology
Journal Article
Neoplasia, ISSN 1476-5586, 12/2007, Volume 9, Issue 12, pp. 1078 - 1090
The capacity of FasL molecules expressed on melanoma cells to induce lymphocyte apoptosis contributes to either antitumor immune response or escape depending... 
apoptosis | FasL | statins | RhoA | Melanoma | Statins | Apoptosis | LIGAND EXPRESSION | CANCER CELLS | TRANSENDOTHELIAL MIGRATION | COUNTERATTACK | IMMUNE ESCAPE | melanoma | MONOCLONAL-ANTIBODY | SMALL GTPASE | TUMOR-NECROSIS-FACTOR | ONCOLOGY | RHO | SURFACE | rho GTP-Binding Proteins - antagonists & inhibitors | Apoptosis - drug effects | Heptanoic Acids - therapeutic use | Recombinant Fusion Proteins - physiology | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Melanoma, Experimental - metabolism | Methionine - pharmacology | rho-Associated Kinases - antagonists & inhibitors | Mevalonic Acid - therapeutic use | Botulinum Toxins - pharmacology | Melanoma, Experimental - immunology | Methionine - analogs & derivatives | Amino Acid Chloromethyl Ketones - pharmacology | Lymphoma - pathology | Benzamides - pharmacology | fas Receptor - physiology | Fas Ligand Protein - biosynthesis | Gene Expression Regulation, Neoplastic - drug effects | Pyrroles - therapeutic use | Heptanoic Acids - pharmacology | Mevalonic Acid - pharmacology | rho-Associated Kinases - physiology | Membrane Proteins - genetics | rho GTP-Binding Proteins - genetics | RNA, Small Interfering - pharmacology | Melanoma, Experimental - pathology | Lymphocytes - cytology | rho GTP-Binding Proteins - physiology | Mevalonic Acid - analogs & derivatives | Membrane Proteins - biosynthesis | Pyrroles - pharmacology | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Cell Line, Tumor - cytology | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - pharmacology | ADP Ribose Transferases - pharmacology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Atorvastatin | Mice | Fas Ligand Protein - genetics | Index Medicus
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 11/2011, Volume 141, Issue 5, p. 1887
Signaling via interleukin (IL)-10 or transforming growth factor (TGF)-[beta] is disrupted in subpopulations of patients with inflammatory bowel disease, but it... 
Interleukins | Fluorescein | Crohn's disease | Biological response modifiers | Transforming growth factors | Enzyme-linked immunosorbent assay | Protein binding
Journal Article