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The Keio Journal of Medicine, ISSN 0022-9717, 2016, Volume 65, Issue 1, pp. 21 - 21
Rapid growing cells like tumor cells need a vast amount of energy to match their high metabolic demand. Guanine triphosphate (GTP) is one of major cellular... 
Journal Article
Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6060, pp. 1278 - 1283
Control of intracellular reactive oxygen species (ROS) concentrations is critical for cancer cell survival. We show that, in human lung cancer cells, acute... 
Antioxidants | Oxidative stress | Medical research | Cellular metabolism | REPORTS | Erythrocytes | Cell lines | Antibodies | Oxidation | Cell membranes | Hemoglobins | CELLS | OXIDATIVE STRESS | PROTEIN | METABOLISM | MULTIDISCIPLINARY SCIENCES | ROS | TUMOR-SUPPRESSOR | ISOFORM | CANCER | Enzyme Activators - pharmacology | Neoplasm Transplantation | Protein Subunits | Reactive Oxygen Species - metabolism | Oxidative Stress | Glutathione - metabolism | Antioxidants - metabolism | Humans | Pyruvate Kinase - chemistry | Diamide - pharmacology | Transplantation, Heterologous | Neoplasms, Experimental - pathology | Mutant Proteins - antagonists & inhibitors | Cell Line | Oxidation-Reduction | Pyruvate Kinase - metabolism | Cell Survival | Mutant Proteins - genetics | Mutant Proteins - metabolism | Cysteine - chemistry | Pyruvate Kinase - antagonists & inhibitors | Animals | Mice, Nude | Mutant Proteins - chemistry | Acetylcysteine - pharmacology | Cell Line, Tumor | Glucose - metabolism | Mice | Neoplasms, Experimental - metabolism | Pentose Phosphate Pathway | Pyruvate Kinase - genetics | Amino Acid Substitution | Reactive oxygen species | Enzyme inhibitors | Pyruvate kinase | Lung cancer | Cancer cells | Physiological aspects | Oxidation-reduction reaction | Research | Health aspects | Enzymes | Biochemistry | Cellular biology | Kinases
Journal Article
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2011, Volume 43, Issue 9, pp. 869 - 874
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2019, Volume 14, Issue 8, p. e0219436
Journal Article
Journal Article
Acta Crystallographica Section A Foundations and Advances, ISSN 2053-2733, 07/2018, Volume 74, Issue a1, pp. a208 - a208
Journal Article
by Yamagami, Keitaro and Kurogi, Ryota and Kurogi, Ai and Nishimura, Kunihiro and Onozuka, Daisuke and Ren, Nice and Kada, Akiko and Nishimura, Ataru and Arimura, Koichi and Ido, Keisuke and Mizoguchi, Masahiro and Sakamoto, Tetsuya and Kayama, Takamasa and Suzuki, Michiyasu and Arai, Hajime and Hagihara, Akihito and Iihara, Koji and Takigami, Masayoshi and Kamiyama, Kenji and Houkin, Kiyohiro and Nishi, Shougo and Yoshimoto, Tetsuyuki and Kaneko, Sadao and Oka, Koji and Ooyama, Hiroshi and Kamada, Kyousuke and Makino, Kenichi and Tokumitsu, Naoki and Sako, Kazuhiro and Suzuki, Susumu and Suzuki, Nozomi and Izumi, Naoto and Nitta, Kazumi and Ootaki, Masahumi and Isobe, Masanori and Nishiya, Mikio and Yamazaki, Takaaki and Mabuchi, Syouji and Ogasawara, Kuniaki and Kubo, Naohiko and Shimizu, Yukihiko and Saito, Keiichi and Yamanome, Tatumi and Yoshino, Atsuo and Fujitsuka, Mitsuyuki and Takami, Masaaki and Ohtaka, Hirotoshi and Hirano, Teruyuki and Shiokawa, Yosiaki and Okada, Takaharu and Suzuki, Ichiro and Kohno, Michihiro and Haraoka, Jou and Arai, Yoshinori and Kawamura, Noriyoshi and Isoshima, Akira and Yasue, Masaharu and Takayoshi Kobayashi, Mitsuhiko Hokari and Kawai, Kensuke and Maehara, Taketoshi and Arai, Hajime and Noguchi, Makoto and Hoshino, Haruhiko and Hiyama, Hirofumi and Yoshida, Kensaku and Utsugi, Osamu and Takeda, Yasuaki and Tamaki, Kouichi and Karasudani, Hirohide and Urabe, Takao and Kobayashi, Shiro and Nakamura, Michio and Koguchi, Yorio and Ono, Junichi and Suda, Sumio and Hadeishi, Hiromu and Fukutake, Toshio and Wakui, Kenji and Tanno, Hirokazu and Ishige, Naoki and Ohasi, Takashi and Sakai, Hideki and Nishimura, Yasuaki and Watanabe, Takayuki and Matsumoto, Takashi and Koketsu, Naoki and Hirose, Yuichi and Doyu, Manabu and Hasegawa, Toshinori and Kuwayama, Naoto and Terao, Shinichi and Mizutani, Nobuhiko and Suzaki, Noriyuki and Okuda, Satoshi and Yasui, Keizo and Seki, Yukio and Hasegawa, Yasuhiro and Ikeda, Akira and Takeuchi, Youtarou and Ohara, Sigeki and ... and J-ASPECT Study Collaborators
World Neurosurgery, ISSN 1878-8750, 10/2019, Volume 130, pp. e26 - e46
The epidemiology of patients with traumatic brain injury (TBI) has changed dramatically over recent decades as a result of rapid advances in aging societies.... 
Aging | Hospital mortality | Prognosis | Traumatic brain injury | Subdural hematoma | SURGERY | CARE | CLINICAL NEUROLOGY | IMPACT | CLINICAL-VARIABLES | HOSPITAL VOLUME | GENDER | COMA
Journal Article
PLOS PATHOGENS, ISSN 1553-7366, 11/2019, Volume 15, Issue 11, p. e1008124
Journal Article
Nature Genetics, ISSN 1061-4036, 05/2012, Volume 44, Issue 5, pp. 511 - 516
Journal Article