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1998, Canadian theses, ISBN 9780612408753
GLP-1 (Glucagon-like peptide-1) and GIP (Glucose-dependent insulinotropic polypeptide) are intestinal hormones that potentiate glucose-stimulated insulin... 
Animals | Anatomy & physiology
Dissertation
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1735 - 10
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 12/2011, Volume 414, Issue 5, pp. 798 - 811
Leukocyte-type core 2 β1,6- -acetylglucosaminyltransferase (C2GnT-L) is an inverting, metal-ion-independent glycosyltransferase that catalyzes the formation of... 
core 2 | GT-A | C2GnT-L | GT-B | glycosyltransferase | Humans | HEK293 Cells | Models, Molecular | N-Acetylglucosaminyltransferases - genetics | Protein Conformation | Mutation | Leukocytes - enzymology | N-Acetylglucosaminyltransferases - chemistry | Amino Acid Motifs | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 11/2008, Volume 205, Issue 12, pp. 2763 - 2779
Progressive loss of T cell functionality is a hallmark of chronic infection with human immunodeficiency virus 1 (HIV-1). We have identified a novel population... 
MEDICINE, RESEARCH & EXPERIMENTAL | SKEWED MATURATION | ACTIVATION | MULTIPLE-SCLEROSIS | IMMUNODEFICIENCY-VIRUS-INFECTION | IMPAIRED FUNCTION | CD4(+) | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | DISEASE PROGRESSION | LYMPHOCYTES | ANTIGEN | GATA3 Transcription Factor - genetics | T-Lymphocyte Subsets - immunology | Antigens, CD - immunology | HIV-1 - pathogenicity | T-Lymphocyte Subsets - cytology | GATA3 Transcription Factor - immunology | Humans | STAT5 Transcription Factor - immunology | T-Box Domain Proteins - immunology | Antigens, CD - genetics | Extracellular Signal-Regulated MAP Kinases - genetics | Extracellular Signal-Regulated MAP Kinases - immunology | HIV Infections - immunology | STAT5 Transcription Factor - genetics | Signal Transduction - immunology | HIV Infections - pathology | Apoptosis Regulatory Proteins - genetics | Apoptosis Regulatory Proteins - immunology | Membrane Proteins - genetics | p38 Mitogen-Activated Protein Kinases - genetics | Membrane Proteins - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Hepatitis A Virus Cellular Receptor 2 | T-Box Domain Proteins - genetics | Disease Progression | Antiretroviral Therapy, Highly Active | HIV-1 - immunology | Phenotype | Animals | T-Lymphocytes - cytology | HIV Infections - drug therapy | Programmed Cell Death 1 Receptor | T-Lymphocytes - immunology | HIV Infections - physiopathology | HLA Antigens | Index Medicus
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 12/2011, Volume 414, Issue 5, p. 798
Leukocyte-type core 2 [beta]1,6-N-acetylglucosaminyltransferase (C2GnT-L) is an inverting, metal-ion-independent glycosyltransferase that catalyzes the... 
Phosphates | Lysine | Transferases | Crystals | Chemical properties | Catalysis | Structure
Journal Article
Vaccine, ISSN 0264-410X, 2012, Volume 30, Issue 20, pp. 3061 - 3067
Highlights ► The antigen was purified from the culture supernatant of transfected human cells. ► The purified recombinant protein is immunogenic in mice after... 
Allergy and Immunology | Adjuvants | Virus neutralization | Subunit vaccine | Measles | MEDICINE, RESEARCH & EXPERIMENTAL | PROTECTION | CRYSTAL-STRUCTURE | CELL-MEDIATED-IMMUNITY | GLYCOPROTEINS | IMMUNOLOGY | CHILDREN | ATYPICAL MEASLES | FUSION PROTEIN | MICE | MONOCLONAL-ANTIBODIES | RHESUS MACAQUES | Cell Line | Hemagglutinins, Viral - genetics | Humans | Interferon-gamma - secretion | Hemagglutinins, Viral - isolation & purification | Measles Vaccine - administration & dosage | Recombinant Proteins - genetics | Th2 Cells - immunology | Vaccines, Subunit - immunology | Vaccines, Synthetic - immunology | Th1 Cells - immunology | Antibodies, Viral - blood | Hemagglutinins, Viral - immunology | Interleukin-5 - secretion | Recombinant Proteins - isolation & purification | Animals | Recombinant Proteins - immunology | Vaccines, Subunit - administration & dosage | Leukocytes, Mononuclear - immunology | Measles Vaccine - immunology | Measles - prevention & control | Mice | Vaccines, Synthetic - administration & dosage | Antibodies, Neutralizing - blood | Virus diseases | Antigens | Lectins | Phosphazo compounds | Vaccines | Recombinant proteins | Cells | Proteins | Medical research | Cloning | Viral infections | Crystal structure | Cell culture | Immunization | Immune response | Immunoglobulin G | Aluminum sulfate | Helper cells | Developing countries | Infants | Lymphocytes T | Immune response (humoral) | Immunity (cell-mediated) | H protein | Interleukin 5 | Immunogenicity | Splenocytes | Hemagglutinins | gamma -Interferon | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2006, Volume 281, Issue 36, pp. 26693 - 26701
Journal Article
Vaccine, ISSN 0264-410X, 2006, Volume 25, Issue 1, pp. 136 - 143
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2006, Volume 281, Issue 36, p. 26693
Leukocyte type core 2 β1,6- N -acetylglucosaminyltransferase (C2GnT-L) is a key enzyme in the biosynthesis of branched O -glycans. It is an inverting, metal... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2006, Volume 281, Issue 36, pp. 26693 - 26701
Leukocyte type core 2 beta 1,6-N-acetylglucosaminyltransferase (C2GnT-L) is a key enzyme in the biosynthesis of branched O-glycans. It is an inverting, metal... 
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2009, Volume 388, Issue 4, pp. 815 - 823
The spike (S) protein of the severe acute respiratory syndrome coronavirus (SARS-CoV) is responsible for host cell attachment and fusion of the viral and host... 
SARS | angiotensin-converting enzyme 2 | spike glycoprotein | immune recognition | SARS-CoV | VIRUS INFECTIVITY | POTENT NEUTRALIZING ANTIBODIES | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUBUNIT VACCINE | ANGIOTENSIN-CONVERTING ENZYME-2 | PROTECTIVE IMMUNITY | SPIKE PROTEIN | MICE | INFLUENZA-VIRUS | HUMAN MONOCLONAL-ANTIBODIES | SARS-CORONAVIRUS | SARS Virus - immunology | Humans | Membrane Glycoproteins - chemistry | Molecular Sequence Data | Crystallography, X-Ray | Recombinant Fusion Proteins - metabolism | Membrane Glycoproteins - immunology | Binding Sites | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Protein Structure, Tertiary | Cell Line | Antibody Formation - immunology | Viral Envelope Proteins - genetics | Models, Molecular | Membrane Glycoproteins - genetics | Spike Glycoprotein, Coronavirus | Animals | Peptidyl-Dipeptidase A - chemistry | Immunoglobulin Fab Fragments - chemistry | Viral Envelope Proteins - chemistry | Recombinant Fusion Proteins - genetics | Viral Envelope Proteins - immunology | Mice | Immunoglobulin Fab Fragments - immunology | Peptidyl-Dipeptidase A - immunology | Enzymes | Molecular genetics | Severe acute respiratory syndrome | Crystals | Monoclonal antibodies | Structure | Protein binding | Index Medicus | ANTIBODIES | ENZYMES | CELL MEMBRANES | CRYSTAL STRUCTURE | HOST | national synchrotron light source | MATERIALS SCIENCE | CHANNELING | INTERACTIONS | PROTEINS | RECEPTORS | SURFACES
Journal Article