2003, ISBN 9784878934971, 237
Book
2.
Characterization of Plant Functions Using Cultured Plant Cells, and Biotechnological Applications
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 01/2013, Volume 77, Issue 1, pp. 1 - 1
Plant cell cultures are widely used in the micro-propagation of clonal plants, especially virus-free plants, and in the production of useful metabolites such...
Journal Article
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 01/2013, Volume 77, Issue 1, pp. 1 - 9
Plant cell cultures are widely used in the micro-propagation of clonal plants, especially virus-free plants, and in the production of useful metabolites such...
somaclonal variation | photoautotrophic culture | functional differentiation | secondary metabolism | benzylisoquinoline alkaloid biosynthesis | Benzylisoquinoline alkaloid biosynthesis | Photoautotrophic culture | Functional differentiation | Somaclonal variation | Secondary metabolism | COCLAURINE N-METHYLTRANSFERASE | NICOTIANA-TABACUM | NORCOCLAURINE 6-O-METHYLTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | ADENOSYL-L-METHIONINE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CHLOROPLASTIC NAD(P)H DEHYDROGENASE | GENE-EXPRESSION | PHOTOSYSTEM-II | MOLECULAR-CLONING | CHEMISTRY, APPLIED | TRANSCRIPTION FACTOR | Coptis - genetics | Biotechnology | Autotrophic Processes - physiology | Coptis - metabolism | Tobacco - metabolism | Cells, Cultured | Plant Cells - physiology | Genetic Engineering | Tobacco - genetics | Gene Expression Regulation, Plant | Photosynthesis - physiology | Cell Differentiation | Alkaloids - biosynthesis | Alkaloids - genetics
somaclonal variation | photoautotrophic culture | functional differentiation | secondary metabolism | benzylisoquinoline alkaloid biosynthesis | Benzylisoquinoline alkaloid biosynthesis | Photoautotrophic culture | Functional differentiation | Somaclonal variation | Secondary metabolism | COCLAURINE N-METHYLTRANSFERASE | NICOTIANA-TABACUM | NORCOCLAURINE 6-O-METHYLTRANSFERASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | ADENOSYL-L-METHIONINE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CHLOROPLASTIC NAD(P)H DEHYDROGENASE | GENE-EXPRESSION | PHOTOSYSTEM-II | MOLECULAR-CLONING | CHEMISTRY, APPLIED | TRANSCRIPTION FACTOR | Coptis - genetics | Biotechnology | Autotrophic Processes - physiology | Coptis - metabolism | Tobacco - metabolism | Cells, Cultured | Plant Cells - physiology | Genetic Engineering | Tobacco - genetics | Gene Expression Regulation, Plant | Photosynthesis - physiology | Cell Differentiation | Alkaloids - biosynthesis | Alkaloids - genetics
Journal Article
1996, Dai 1-han., ISBN 4634610604, viii, 288, 19
Book
2016, Shohan., ISBN 4838233094, 277 pages
Book
2013, ISBN 4000113127, v
Book
Plant Biotechnology, ISSN 1342-4580, 2018
Plants grow under threats of environmental changes that could injure cellular viability and damage whole-plant physiology. To defend themselves against such...
light stress | transcription factors | ERF | anthocyanin | gene expression
light stress | transcription factors | ERF | anthocyanin | gene expression
Journal Article
Pattern Recognition Letters, ISSN 0167-8655, 06/2019, Volume 124, pp. 91 - 99
In this paper, we propose a new method for reconstructing 3D objects under light ray distortion caused by unknown refractive media. The proposed method can...
Reconstruction | Distortion | Cameras | Mathematical models | Parameters | Raindrops
Reconstruction | Distortion | Cameras | Mathematical models | Parameters | Raindrops
Journal Article
Scientific Reports, ISSN 2045-2322, 08/2016, Volume 6, Issue 1, p. 31988
Benzylisoquinoline alkaloids (BIQ) are among the most structurally diverse and pharmaceutically valuable secondary metabolites. A plant-specific WRKY-type...
CELLS | REGULATOR | LRR PROTEIN | COPTIS-JAPONICA | BLAST-RESISTANCE | MULTIDISCIPLINARY SCIENCES | PLANTS | SUPERFAMILY | ARABIDOPSIS | PROGRAM | REVEALS | Phosphorylation | Immunoprecipitation | Transcription Factors - chemistry | Coptis - metabolism | Transcriptional Activation - drug effects | Benzylisoquinolines - chemistry | Protease Inhibitors - pharmacology | Proteolysis - drug effects | Cell Nucleus - metabolism | Plant Proteins - chemistry | Electrophoretic Mobility Shift Assay | Plant Proteins - metabolism | Alkaloids - biosynthesis | Mutagenesis, Site-Directed | Plant Cells - metabolism | Cells, Cultured | Proteasome Endopeptidase Complex - chemistry | DNA - metabolism | Transcription Factors - genetics | Coptis - cytology | Transcription Factors - metabolism | Leupeptins - pharmacology | Plant Proteins - genetics | DNA - chemistry | Gene Expression Regulation, Plant - drug effects | Tyrosine - metabolism | Benzylisoquinolines - metabolism | Protein Binding | Proteasome Endopeptidase Complex - metabolism | Alkaloids - chemistry | Tyrosine | Enzymes | Biosynthesis | Proteinase inhibitors | Gene expression | Kinases | Proteins | Alkaloids | Secondary metabolites | Metabolites | Transcription activation | Cell lines | Post-translation | Localization | Deoxyribonucleic acid--DNA
CELLS | REGULATOR | LRR PROTEIN | COPTIS-JAPONICA | BLAST-RESISTANCE | MULTIDISCIPLINARY SCIENCES | PLANTS | SUPERFAMILY | ARABIDOPSIS | PROGRAM | REVEALS | Phosphorylation | Immunoprecipitation | Transcription Factors - chemistry | Coptis - metabolism | Transcriptional Activation - drug effects | Benzylisoquinolines - chemistry | Protease Inhibitors - pharmacology | Proteolysis - drug effects | Cell Nucleus - metabolism | Plant Proteins - chemistry | Electrophoretic Mobility Shift Assay | Plant Proteins - metabolism | Alkaloids - biosynthesis | Mutagenesis, Site-Directed | Plant Cells - metabolism | Cells, Cultured | Proteasome Endopeptidase Complex - chemistry | DNA - metabolism | Transcription Factors - genetics | Coptis - cytology | Transcription Factors - metabolism | Leupeptins - pharmacology | Plant Proteins - genetics | DNA - chemistry | Gene Expression Regulation, Plant - drug effects | Tyrosine - metabolism | Benzylisoquinolines - metabolism | Protein Binding | Proteasome Endopeptidase Complex - metabolism | Alkaloids - chemistry | Tyrosine | Enzymes | Biosynthesis | Proteinase inhibitors | Gene expression | Kinases | Proteins | Alkaloids | Secondary metabolites | Metabolites | Transcription activation | Cell lines | Post-translation | Localization | Deoxyribonucleic acid--DNA
Journal Article
Plant Physiology, ISSN 0032-0889, 10/2017, Volume 175, Issue 2, pp. 874 - 885
Combinations of mutations in miR319 and TCP transcription factor genes in Arabidopsis thaliana generate cotyledon fusion and various leaf forms with a broad...
Journal Article
Genes to Cells, ISSN 1356-9597, 01/2019, Volume 24, Issue 1, pp. 70 - 81
Epigenetic mechanisms allow for transgenerational memory of an ancestor's environment and can affect the gene expression, physiology and phenotype of that...
Caenorhabditis elegans | Nile red fluorescence | sanguinarine | lipid | epigenetics | transgenerational inheritance | berberine | LIFE-SPAN | GERMLINE | MECHANISM | CELL BIOLOGY | EPIGENETIC INHERITANCE | METABOLISM | MEMORY | GENETICS & HEREDITY | FAT | C-ELEGANS | THERMOTOLERANCE | Alkaloids | Berberine | Phenotypes | Life span | Nucleotide sequence | Nematodes | Lipids | Heredity | Gene expression | Sanguinarine | Drug development | Worms
Caenorhabditis elegans | Nile red fluorescence | sanguinarine | lipid | epigenetics | transgenerational inheritance | berberine | LIFE-SPAN | GERMLINE | MECHANISM | CELL BIOLOGY | EPIGENETIC INHERITANCE | METABOLISM | MEMORY | GENETICS & HEREDITY | FAT | C-ELEGANS | THERMOTOLERANCE | Alkaloids | Berberine | Phenotypes | Life span | Nucleotide sequence | Nematodes | Lipids | Heredity | Gene expression | Sanguinarine | Drug development | Worms
Journal Article
Nature Genetics, ISSN 1061-4036, 11/2015, Volume 47, Issue 11, pp. 1304 - 1315
Adult T cell leukemia/lymphoma (ATL) is a peripheral T cell neoplasm of largely unknown genetic basis, associated with human T cell leukemia virus type-1...
TRANSCRIPTION FACTORS | KAPPA-B ACTIVATION | DNA METHYLATION | VIRUS TYPE-I | PROTEIN-KINASE | GENETICS & HEREDITY | HTLV-1 | HUMAN CANCERS | MUTATIONS | EXPRESSION | LYMPHOBLASTIC-LEUKEMIA | Amino Acid Sequence | Jurkat Cells | Leukemia-Lymphoma, Adult T-Cell - genetics | Humans | Molecular Sequence Data | Gene Products, tax - genetics | Signal Transduction - genetics | Transcriptome - genetics | Human T-lymphotropic virus 1 - physiology | Leukemia-Lymphoma, Adult T-Cell - virology | Genome, Human - genetics | T-Lymphocytes - virology | DNA Copy Number Variations | Sequence Homology, Amino Acid | DNA Methylation | Exome - genetics | Host-Pathogen Interactions - genetics | T-Lymphocytes - metabolism | HEK293 Cells | Survival Analysis | Adult | Human T-lymphotropic virus 1 - genetics | Mutation | Sequence Analysis, DNA - methods | Gene mutations | Leukemia | Development and progression | Genetic aspects | Cellular signal transduction | Genetic transcription | T cells | Health aspects | Identification and classification | Hematology | Research & development--R&D | Pathogenesis | Lymphocytes | Genomics | Science | Genomes | Gene expression | Cancer
TRANSCRIPTION FACTORS | KAPPA-B ACTIVATION | DNA METHYLATION | VIRUS TYPE-I | PROTEIN-KINASE | GENETICS & HEREDITY | HTLV-1 | HUMAN CANCERS | MUTATIONS | EXPRESSION | LYMPHOBLASTIC-LEUKEMIA | Amino Acid Sequence | Jurkat Cells | Leukemia-Lymphoma, Adult T-Cell - genetics | Humans | Molecular Sequence Data | Gene Products, tax - genetics | Signal Transduction - genetics | Transcriptome - genetics | Human T-lymphotropic virus 1 - physiology | Leukemia-Lymphoma, Adult T-Cell - virology | Genome, Human - genetics | T-Lymphocytes - virology | DNA Copy Number Variations | Sequence Homology, Amino Acid | DNA Methylation | Exome - genetics | Host-Pathogen Interactions - genetics | T-Lymphocytes - metabolism | HEK293 Cells | Survival Analysis | Adult | Human T-lymphotropic virus 1 - genetics | Mutation | Sequence Analysis, DNA - methods | Gene mutations | Leukemia | Development and progression | Genetic aspects | Cellular signal transduction | Genetic transcription | T cells | Health aspects | Identification and classification | Hematology | Research & development--R&D | Pathogenesis | Lymphocytes | Genomics | Science | Genomes | Gene expression | Cancer
Journal Article
Nature Communications, ISSN 2041-1723, 2011, Volume 2, Issue 1, p. 326
The secondary metabolites of higher plants include diverse chemicals, such as alkaloids, isoprenoids and phenolic compounds (phenylpropanoids and flavonoids)....
MICROORGANISMS | STRAINS | ENZYME | PATHWAY | BIOSYNTHESIS | TYROSINASE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | PURIFICATION | BENZYLISOQUINOLINE ALKALOIDS | OPIUM POPPY | Biotechnology - methods | Plants - metabolism | Genetic Engineering | Benzylisoquinolines - metabolism | Escherichia coli - genetics | Escherichia coli - metabolism | Biosynthetic Pathways | Fermentation
MICROORGANISMS | STRAINS | ENZYME | PATHWAY | BIOSYNTHESIS | TYROSINASE | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | PURIFICATION | BENZYLISOQUINOLINE ALKALOIDS | OPIUM POPPY | Biotechnology - methods | Plants - metabolism | Genetic Engineering | Benzylisoquinolines - metabolism | Escherichia coli - genetics | Escherichia coli - metabolism | Biosynthetic Pathways | Fermentation
Journal Article
IOP Conference Series: Materials Science and Engineering, ISSN 1757-8981, 11/2017, Volume 269, Issue 1, p. 12079
Conference Proceeding
15.
Full Text
Total biosynthesis of opiates by stepwise fermentation using engineered Escherichia coli
Nature Communications, ISSN 2041-1723, 02/2016, Volume 7, Issue 1, p. 10390
Opiates such as morphine and codeine are mainly obtained by extraction from opium poppies. Fermentative opiate production in microbes has also been...
YEAST | COPTIS-JAPONICA | NORCOCLAURINE 6-O-METHYLTRANSFERASE | MULTIDISCIPLINARY SCIENCES | PURIFICATION | BENZYLISOQUINOLINE ALKALOIDS | MICROBIAL-PRODUCTION | MORPHINE BIOSYNTHESIS | SACCHAROMYCES-CEREVISIAE | BACTERIAL EXPRESSION | OPIUM POPPY | Coptis - genetics | Codeine - biosynthesis | Oxidoreductases - genetics | Methyltransferases - metabolism | Methyltransferases - genetics | Morphine - biosynthesis | Papaver - genetics | Fermentation | Acetyltransferases - genetics | Hydrocodone - metabolism | Thebaine - metabolism | Benzylisoquinolines - metabolism | Glycerol - metabolism | Escherichia coli - genetics | Escherichia coli - metabolism | Organisms, Genetically Modified - metabolism | Analgesics, Opioid - metabolism | Organisms, Genetically Modified - genetics | Oxycodone - metabolism
YEAST | COPTIS-JAPONICA | NORCOCLAURINE 6-O-METHYLTRANSFERASE | MULTIDISCIPLINARY SCIENCES | PURIFICATION | BENZYLISOQUINOLINE ALKALOIDS | MICROBIAL-PRODUCTION | MORPHINE BIOSYNTHESIS | SACCHAROMYCES-CEREVISIAE | BACTERIAL EXPRESSION | OPIUM POPPY | Coptis - genetics | Codeine - biosynthesis | Oxidoreductases - genetics | Methyltransferases - metabolism | Methyltransferases - genetics | Morphine - biosynthesis | Papaver - genetics | Fermentation | Acetyltransferases - genetics | Hydrocodone - metabolism | Thebaine - metabolism | Benzylisoquinolines - metabolism | Glycerol - metabolism | Escherichia coli - genetics | Escherichia coli - metabolism | Organisms, Genetically Modified - metabolism | Analgesics, Opioid - metabolism | Organisms, Genetically Modified - genetics | Oxycodone - metabolism
Journal Article
Cancer Science, ISSN 1347-9032, 05/2013, Volume 104, Issue 5, pp. 647 - 650
We report an adult T‐cell leukemia/lymphoma patient suffering from Stevens–Johnson Syndrome (SJS) during mogamulizumab (humanized anti‐CCR4 monoclonal...
Antibodies, Monoclonal, Humanized - adverse effects | Stevens-Johnson Syndrome - chemically induced | Stevens-Johnson Syndrome - immunology | Antibodies, Monoclonal, Humanized - therapeutic use | Leukemia-Lymphoma, Adult T-Cell - drug therapy | Humans | Female | Aged | Leukemia-Lymphoma, Adult T-Cell - immunology | Stevens-Johnson syndrome | Care and treatment | Leukemia | Monoclonal antibodies | Lymphomas | T cells | Cancer | Index Medicus
Antibodies, Monoclonal, Humanized - adverse effects | Stevens-Johnson Syndrome - chemically induced | Stevens-Johnson Syndrome - immunology | Antibodies, Monoclonal, Humanized - therapeutic use | Leukemia-Lymphoma, Adult T-Cell - drug therapy | Humans | Female | Aged | Leukemia-Lymphoma, Adult T-Cell - immunology | Stevens-Johnson syndrome | Care and treatment | Leukemia | Monoclonal antibodies | Lymphomas | T cells | Cancer | Index Medicus
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 2011, Volume 507, Issue 1, pp. 194 - 203
► Unusual P450 reactions in isoquinoline alkaloid biosynthesis and other plant secondary metabolisms are presented. ►The proposed mechanisms of unusual P450...
P450 | Isoquinoline alkaloids | Plant secondary metabolism | Methylenedioxy bridge | Oxidative rearrangement | Phenol coupling | CYTOCHROME-P450 MONOOXYGENASE | ISOFLAVONE BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2-HYDROXYISOFLAVANONE SYNTHASE | AMINO-ACID | ALKALOID BIOSYNTHESIS | BIOPHYSICS | FUNCTIONAL EXPRESSION | MOLECULAR-CLONING | HETEROLOGOUS EXPRESSION | COPTIS-JAPONICA CELLS | Isoquinolines - metabolism | Isoquinolines - chemistry | Plants - metabolism | Oxidation-Reduction | Cytochrome P-450 Enzyme System - metabolism | Phenols - chemistry | Alkaloids - metabolism | Phenols - metabolism | Alkaloids - chemistry | Plants - enzymology | Physiological aspects | Alkaloids
P450 | Isoquinoline alkaloids | Plant secondary metabolism | Methylenedioxy bridge | Oxidative rearrangement | Phenol coupling | CYTOCHROME-P450 MONOOXYGENASE | ISOFLAVONE BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2-HYDROXYISOFLAVANONE SYNTHASE | AMINO-ACID | ALKALOID BIOSYNTHESIS | BIOPHYSICS | FUNCTIONAL EXPRESSION | MOLECULAR-CLONING | HETEROLOGOUS EXPRESSION | COPTIS-JAPONICA CELLS | Isoquinolines - metabolism | Isoquinolines - chemistry | Plants - metabolism | Oxidation-Reduction | Cytochrome P-450 Enzyme System - metabolism | Phenols - chemistry | Alkaloids - metabolism | Phenols - metabolism | Alkaloids - chemistry | Plants - enzymology | Physiological aspects | Alkaloids
Journal Article
Nature Communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 1367 - 1367
A method for stimulating the differentiation of human pluripotent stem cells into kidney lineages remains to be developed. Most cells in kidney are derived...
LONG-TERM | MAINTENANCE | POPULATION | MULTIDISCIPLINARY SCIENCES | MOUSE | GENERATION | DIFFERENTIATION | KIDNEY | ESTABLISHMENT | EXPRESSION | LINES | Cell Line | Gene Dosage - genetics | Gene Targeting | Green Fluorescent Proteins - metabolism | Embryonic Stem Cells - cytology | Kidney - embryology | Mesoderm - embryology | Humans | Genetic Loci - genetics | Kidney - cytology | Mesoderm - cytology | Gene Knock-In Techniques | Kidney - metabolism | Animals | Embryoid Bodies - cytology | Flow Cytometry | Time Factors | Gene Expression Regulation, Developmental | Polymorphism, Single Nucleotide - genetics | Cell Differentiation | Mice | Induced Pluripotent Stem Cells - cytology | Protein-Serine-Threonine Kinases - metabolism | Induced Pluripotent Stem Cells - metabolism
LONG-TERM | MAINTENANCE | POPULATION | MULTIDISCIPLINARY SCIENCES | MOUSE | GENERATION | DIFFERENTIATION | KIDNEY | ESTABLISHMENT | EXPRESSION | LINES | Cell Line | Gene Dosage - genetics | Gene Targeting | Green Fluorescent Proteins - metabolism | Embryonic Stem Cells - cytology | Kidney - embryology | Mesoderm - embryology | Humans | Genetic Loci - genetics | Kidney - cytology | Mesoderm - cytology | Gene Knock-In Techniques | Kidney - metabolism | Animals | Embryoid Bodies - cytology | Flow Cytometry | Time Factors | Gene Expression Regulation, Developmental | Polymorphism, Single Nucleotide - genetics | Cell Differentiation | Mice | Induced Pluripotent Stem Cells - cytology | Protein-Serine-Threonine Kinases - metabolism | Induced Pluripotent Stem Cells - metabolism
Journal Article
Scientific Reports, ISSN 2045-2322, 2016, Volume 6, Issue 1, p. 22201
Stylopine is a protoberberine-type alkaloid that has potential biological activities. Based on the successful microbial production of (S)-reticuline, we...
MECHANISM | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | BERBERINE BRIDGE ENZYME | PLANTS | MOLECULAR-CLONING | CULTURES | ALKALOIDS | Berberine Alkaloids - metabolism | Gene Expression | Pichia - metabolism | Coculture Techniques | Mass Spectrometry | Pichia - genetics | Berberine Alkaloids - chemistry | Chromatography, Liquid | Fermentation | Berberine Alkaloids - isolation & purification | Berberine | Enzymes | Cell culture | Cell lines | Methanol
MECHANISM | BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | BERBERINE BRIDGE ENZYME | PLANTS | MOLECULAR-CLONING | CULTURES | ALKALOIDS | Berberine Alkaloids - metabolism | Gene Expression | Pichia - metabolism | Coculture Techniques | Mass Spectrometry | Pichia - genetics | Berberine Alkaloids - chemistry | Chromatography, Liquid | Fermentation | Berberine Alkaloids - isolation & purification | Berberine | Enzymes | Cell culture | Cell lines | Methanol
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 7, pp. 1107 - 1111
Liposomes have been used as targeting carriers for drug delivery systems (DDSs), and the carriers are able to be modified with targeting ligands, such as...
drug delivery system | C16Y peptide | nano carrier | screening array | Screening array | Drug delivery system | Nano carrier | ANTAGONIST | CHOLESTEROL | DOXORUBICIN | ANTIBODY | DELIVERY | CIRCULATION TIME | ULTRASOUND | POLY(ETHYLENE GLYCOL) | BUBBLE LIPOSOMES | PHARMACOLOGY & PHARMACY | PEG LIPOSOMES | Cell culture |
drug delivery system | C16Y peptide | nano carrier | screening array | Screening array | Drug delivery system | Nano carrier | ANTAGONIST | CHOLESTEROL | DOXORUBICIN | ANTIBODY | DELIVERY | CIRCULATION TIME | ULTRASOUND | POLY(ETHYLENE GLYCOL) | BUBBLE LIPOSOMES | PHARMACOLOGY & PHARMACY | PEG LIPOSOMES | Cell culture |