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Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 01/2019, Volume 163, pp. 39 - 44
Ga-RM2 is a gastrin releasing peptide receptor (GRPR) antagonist PET (positron emission tomography) radiotracer which is being investigated in clinical trials... 
Gastrin releasing peptide receptor (GRPR) | 68Ge/68Ga generators | Prostate cancer | 68Ga-RM2 | Cold kits | Ga-RM2 | Ga generators | Ge
Journal Article
Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 01/2019, Volume 163, p. 39
.sup.68Ga-RM2 is a gastrin releasing peptide receptor (GRPR) antagonist PET (positron emission tomography) radiotracer which is being investigated in clinical... 
Hydrochloric acid | Medical research | Bombesin | Gastrin | Medicine, Experimental | Prostate cancer
Journal Article
Journal of Peptide Science, ISSN 1075-2617, 07/2019, Volume 25, Issue 7, p. n/a
The present study describes modification of asparagine–glycine–arginine (NGR) peptide at N‐terminally and C‐terminally by introduction of a tridentate... 
N‐terminal | NGR peptide | click ligation | [99mTc(CO)3(H2O)3]+ core | C‐terminal | tridentate scaffold | Spleen | Heart | Stomach | Peptides | Melanoma | Organs | Pharmacology | Glycine | Blood | Organic chemistry | Arginine | Lungs | Coinjection | Asparagine | Chelation | In vivo methods and tests | Chemical synthesis | Pharmacokinetics | Tumors
Journal Article
Chemical Biology and Drug Design, ISSN 1747-0277, 03/2018, Volume 91, Issue 3, pp. 781 - 788
The biological behavior of Ga-based radiopharmaceuticals can be significantly affected by the chelators' attributes (size, charge, lipophilicity). Thus, this... 
HBED-CC | DOTAGA | NGR peptide | NODAGA
Journal Article
Chemical Biology & Drug Design, ISSN 1747-0277, 03/2018, Volume 91, Issue 3, pp. 781 - 788
The biological behavior of 68Ga‐based radiopharmaceuticals can be significantly affected by the chelators’ attributes (size, charge, lipophilicity). Thus, this... 
HBED‐CC | DOTAGA | NGR peptide | NODAGA | 68Ga | Peptides | Comparative analysis | Chelates | Investigations | Tumors
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 02/2018, Volume 61, Issue 2, pp. 68 - 76
The tripeptide sequence asparagine‐glycine‐arginine (NGR) specifically recognizes aminopeptidase N (APN or CD13) receptors highly expressed on tumor cells and... 
Tc‐99m | NGR peptide | polyethylene glycol (PEG) | HT‐1080 tumor | HYNIC | Tc-99m | HT-1080 tumor | Sarcoma | Comparative analysis | Investigations
Journal Article
Chemical Biology & Drug Design, ISSN 1747-0277, 05/2016, Volume 87, Issue 5, pp. 680 - 686
With an aim of developing a bacteria‐specific molecular imaging agent, ciprofloxacin has been modified with a propylamine spacer and linked to two common... 
DOTA | NOTA | bacterial infection | 68Ga | ciprofloxacin | Ciprofloxacin | Health aspects | Bacterial infections
Journal Article
Journal of Pharmaceutical and Biomedical Analysis, ISSN 0731-7085, 04/2018, Volume 152, pp. 173 - 178
This study explores the potential of Lu-labeled carbon nanospheres as radio-nanoprobes for molecular imaging and therapy. The carboxyl functionalized surface... 
DOTA | NGR peptide | Carbon nanospheres | 177Lu | Theranostic | Tumor vasculature
Journal Article
Journal of pharmaceutical and biomedical analysis, ISSN 0731-7085, 04/2018, Volume 152, pp. 173 - 178
This study explores the potential of Lu-labeled carbon nanospheres as radio-nanoprobes for molecular imaging and therapy. The carboxyl functionalized surface... 
Carbon - metabolism | Humans | Oligopeptides - metabolism | Peptides, Cyclic - metabolism | Radioisotopes - metabolism | Tissue Distribution | Radiopharmaceuticals - metabolism | Isotope Labeling - methods | Animals | Nanospheres - metabolism | Cell Line, Tumor | Mice | Lutetium - metabolism
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 07/2017, Volume 60, Issue 9, pp. 431 - 438
Targeted delivery of chemotherapeutic drug at the tumor site enhances the efficacy with minimum systemic exposure. Towards this, drugs conjugated with peptides... 
NGR peptide | chlorambucil | 99mTc‐HYNIC | cytotoxicity | peptide‐drug conjugate | Tc-HYNIC | peptide-drug conjugate | Antimitotic agents | Chemotherapy | Antineoplastic agents | Cancer
Journal Article
Journal Article
Journal of peptide science : an official publication of the European Peptide Society, ISSN 1075-2617, 07/2019, Volume 25, Issue 7, p. e3192
The present study describes modification of asparagine-glycine-arginine (NGR) peptide at N-terminally and C-terminally by introduction of a tridentate... 
Journal Article
Chemical Biology & Drug Design, ISSN 1747-0277, 05/2016, Volume 87, Issue 5, pp. 680 - 686
With an aim of developing a bacteria-specific molecular imaging agent, ciprofloxacin has been modified with a propylamine spacer and linked to two common... 
Journal Article
Journal of labelled compounds & radiopharmaceuticals, ISSN 0362-4803, 08/2019
The acyclic chelator HBED-CC has attained huge clinical significance owing to high thermodynamic and kinetic stability of Ga-HBED-CC chelate. It provides an... 
Journal Article
RSC Advances, ISSN 2046-2069, 05/2016, Volume 6, Issue 56, pp. 5761 - 5769
Multi-functional nanomaterial conjugates constructed with targeting ligands and therapeutic radioisotopes are key for the future clinical translation of... 
Journal Article
Journal of Radioanalytical and Nuclear Chemistry, ISSN 0236-5731, 11/2014, Volume 302, Issue 2, pp. 765 - 771
Catalyst-free click reactions are effective chemical tools for synthesis of radiometal-based radiopharmaceuticals offering advantages towards preparation of... 
A20FMDV2 | Chemistry | Strain-promoted click | Nuclear Physics, Heavy Ions, Hadrons | Diagnostic Radiology | Physical Chemistry | 64 Cu | Inorganic Chemistry | Nuclear Chemistry | α v β 6 Integrin | Integrin
Journal Article
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