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by Webb, Thomas R., PhD and Erdmann, Jeanette, PhD and Stirrups, Kathleen E., PhD and Stitziel, Nathan O., MD, PhD and Masca, Nicholas G.D., PhD and Jansen, Henning, MD and Kanoni, Stavroula, PhD and Nelson, Christopher P., PhD and Ferrario, Paola G., PhD and König, Inke R., PhD and Eicher, John D., PhD and Johnson, Andrew D., PhD and Hamby, Stephen E., PhD and Betsholtz, Christer, PhD and Ruusalepp, Arno, MD, PhD and Franzén, Oscar, PhD and Schadt, Eric E., MD, PhD and Björkegren, Johan L.M., MD, PhD and Weeke, Peter E., MD, PhD and Auer, Paul L., PhD and Schick, Ursula M., PhD and Lu, Yingchang, MD, PhD and Zhang, He, PhD and Dube, Marie-Pierre, PhD and Goel, Anuj, MSc and Farrall, Martin, MD and Peloso, Gina M., PhD and Won, Hong-Hee, PhD and Do, Ron, PhD and van Iperen, Erik, MSc and Kruppa, Jochen, PhD and Mahajan, Anubha, PhD and Scott, Robert A., PhD and Willenborg, Christina, PhD and Braund, Peter S., PhD and van Capelleveen, Julian C., MD and Doney, Alex S.F., MD, PhD and Donnelly, Louise A., PhD and Asselta, Rosanna, PhD and Merlini, Pier A., MD and Duga, Stefano, PhD and Marziliano, Nicola, PhD and Denny, Josh C., MD, MS and Shaffer, Christian, BS and El-Mokhtari, Nour Eddine, MD and Franke, Andre, PhD and Heilmann, Stefanie, PhD and Hengstenberg, Christian, MD and Hoffmann, Per, PhD and Holmen, Oddgeir L., MD and Hveem, Kristian, MD, PhD and Jansson, Jan-Håkan, MD, PhD and Jöckel, Karl-Heinz, PhD and Kessler, Thorsten, MD and Kriebel, Jennifer, PhD and Laugwitz, Karl L., MD and Marouli, Eirini, MSc and Martinelli, Nicola, MD, PhD and McCarthy, Mark I., MD and Van Zuydam, Natalie R., PhD and Meisinger, Christa, MD, MPH and Esko, Tõnu, PhD and Mihailov, Evelin, MSc and Escher, Stefan A., PhD and Alver, Maris, MSc and Moebus, Susanne, PhD and Morris, Andrew D., MD and Virtamo, Jarma, MD, PhD and Nikpay, Majid, PhD and Olivieri, Oliviero, MD and Provost, Sylvie, MSc and AlQarawi, Alaa, BSc and Robertson, Neil R., MSc and Akinsansya, Karen O., PhD and Reilly, Dermot F., PhD and Vogt, Thomas F., PhD and Yin, Wu, PhD and Asselbergs, Folkert W., MD, PhD and Kooperberg, Charles, PhD and Jackson, Rebecca D., MD and Stahl, Eli, PhD and Müller-Nurasyid, Martina, PhD and Strauch, Konstantin, PhD and Varga, Tibor V., PhD and Waldenberger, Melanie, PhD and Zeng, Lingyao, MSc and Chowdhury, Rajiv, MD, PhD and Salomaa, Veikko, MD, PhD and Ford, Ian, PhD and Jukema, J. Wouter, MD, PhD and Amouyel, Philippe, MD, PhD and Kontto, Jukka, MSSc and Nordestgaard, Børge G., MD, DMSc and Ferrières, Jean, MD and Saleheen, Danish, MBBS, PhD and Sattar, Naveed, PhD and Surendran, Praveen, PhD and Wagner, Aline, MD, PhD and Young, Robin, PhD and Howson, Joanna M.M., PhD and ... and Wellcome Trust Case Control and MORGAM Investigators and Myocardial Infarction Genetics and Wellcome Trust Case Control Consortium and Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Medicin
Journal of the American College of Cardiology, ISSN 0735-1097, 2017, Volume 69, Issue 7, pp. 823 - 836
Abstract Background Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show... 
Cardiovascular | Internal Medicine | expression quantitative trait loci | genetics | genome-wide association | single nucleotide polymorphism | cholesteryl ester transfer protein | SR-BI | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | CETP MASS | SUSCEPTIBILITY | RISK | PHOSPHOLIPASE A | VARIANT | SCAVENGER RECEPTOR | ABDOMINAL AORTIC-ANEURYSM | Genome-Wide Association Study | Gene Frequency | Humans | Coronary Artery Disease - genetics | Female | Male | Coronary Artery Disease - epidemiology | Genetic Pleiotropy | Polymorphism, Single Nucleotide | Genetic Loci | Odds Ratio | Case-Control Studies | Coronary heart disease | Analysis | Genealogy | Cardiovascular disease | Genomes | Metabolism | Gene expression | Blood | Risk factors | Studies | Celiac disease | Lipoproteins | Coronary vessels | Rheumatoid arthritis | Quality control | Calcification | Diabetes | Bioinformatics | LD, linkage disequilibrium | CETP, cholesteryl ester transfer protein | eQTL, expression quantitative trait locus | CAD, coronary artery disease | GWAS, genome-wide association study | BMI, body mass index | SNP, single nucleotide polymorphism | HDL, high-density lipoprotein | LDL, low-density lipoprotein | Original Investigation | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Kardiologi | Medical Genetics | Medicinsk genetik | Clinical Medicine | Cardiac and Cardiovascular Systems | Medicinska och farmaceutiska grundvetenskaper
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 70, Issue 6, pp. 704 - 712
Abstract Background Sodium glucose co-transporter 2 (SGLT2) inhibitors may reduce cardiovascular and heart failure risk in patients with type 2 diabetes... 
Cardiovascular | Internal Medicine | high-sensitivity troponin | galectin-3 | N-terminal pro–B-type natriuretic peptide | cardiovascular stress | sodium glucose co-transporter 2 inhibitor | soluble ST2 | CARDIAC & CARDIOVASCULAR SYSTEMS | RATIONALE | RISK | MELLITUS | BASE-LINE CHARACTERISTICS | HEART | DISEASE | HYPOTHESIS | PLACEBO-CONTROLLED TRIAL | INHIBITORS | N-terminal pro-B-type natriuretic peptide | EMPAGLIFLOZIN | Hypoglycemic Agents - therapeutic use | Cardiovascular Diseases - etiology | Double-Blind Method | Follow-Up Studies | Humans | Middle Aged | Male | Biomarkers - blood | Troponin I - blood | Blood Glucose - drug effects | Diabetes Mellitus, Type 2 - blood | Time Factors | Canagliflozin - therapeutic use | Peptide Fragments - blood | Aged, 80 and over | Cardiovascular Diseases - blood | Female | Aged | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Diabetes Mellitus, Type 2 - complications | Natriuretic Peptide, Brain - blood | Type 2 diabetes | Medical research | Analysis | Cardiac patients | Medicine, Experimental | Glucose | Biological markers | Dextrose | Natriuretic peptides | Heart | Elderly people | Heart attacks | Peptides | Cardiovascular disease | Galectin-3 | Older people | Calcium-binding protein | Heart diseases | Age | Glucose transporter | Heart failure | Brain natriuretic peptide | Diabetes mellitus | Health risks | Patients | Troponin | Inhibitors | Troponin I | Sodium | Biomarkers | Adults | Diabetes | Cardiovascular diseases
Journal Article
Lancet, The, ISSN 0140-6736, 2016, Volume 388, pp. S9 - S9
Abstract Background Higher body-mass index (BMI) is a risk factor for cardiometabolic disease, although the underlying causal associations remain unclear. The... 
Internal Medicine | Medicine, Experimental | Medical research | Body mass index | Genetics | Epidemiology | Physicians
Journal Article
Best Practice & Research: Clinical Endocrinology & Metabolism, ISSN 1521-690X, 2013, Volume 27, Issue 4, pp. 501 - 507
Journal Article
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 10, pp. 1200 - 1210
Abstract Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty... 
Cardiovascular | Internal Medicine | drug development | Mendelian randomization | metabolomics | cholesterol lowering | lipoproteins | COHORT PROFILE | CARDIAC & CARDIOVASCULAR SYSTEMS | BIOMARKER | VARIANTS | FATTY-ACID-COMPOSITION | RISK | TRIGLYCERIDES | LDL CHOLESTEROL | CORONARY-HEART-DISEASE | ASSOCIATION | EPIDEMIOLOGY | Hydroxymethylglutaryl CoA Reductases - drug effects | Mendelian Randomization Analysis - methods | Magnetic Resonance Spectroscopy - methods | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Male | United Kingdom | Cardiovascular Diseases - genetics | Forecasting | Metabolomics - methods | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Finland | Cardiovascular Diseases - blood | Adult | Female | Retrospective Studies | Hydroxymethylglutaryl CoA Reductases - blood | Hydroxymethylglutaryl CoA Reductases - genetics | Medical colleges | Metabolites | Pharmacy | Genomics | Genetic research | Drugstores | Fatty acids | Epidemiology | Statins | Public health | Cardiovascular agents | Lipids | Cholesterol | LDL-C, low-density lipoprotein cholesterol | CVD, cardiovascular disease | IDL, intermediate-density lipoprotein | VLDL, very-low-density lipoprotein | HMGCR, HMG-CoA reductase | NMR, nuclear magnetic resonance | HDL, high-density lipoprotein | Original Investigation
Journal Article
Journal Article