The New England Journal of Medicine, ISSN 0028-4793, 11/2009, Volume 361, Issue 21, pp. 2033 - 2045
Genetic analyses showed that mutations affecting the interleukin-10 receptor are associated with early-onset colitis. Further molecular analyses showed that...
INTESTINAL INFLAMMATION | MEDICINE, GENERAL & INTERNAL | CYTOKINE PRODUCTION | CROHNS-DISEASE | CRYSTAL-STRUCTURE | ULCERATIVE-COLITIS | AUTOSOMAL RECESSIVE ENTEROCOLITIS | SEQUENCE VARIANTS | LOCI CONTRIBUTE | IL-10 | GENOME-WIDE ASSOCIATION | Tumor Necrosis Factor-alpha - metabolism | Humans | Infant | Male | Mutation, Missense | Remission Induction | Sequence Analysis, DNA | Stem Cell Transplantation | Interleukin-10 Receptor alpha Subunit - chemistry | Interleukin-10 Receptor beta Subunit - chemistry | Interleukin-10 Receptor alpha Subunit - genetics | Pedigree | Age of Onset | Inflammatory Bowel Diseases - genetics | Interleukin-10 - metabolism | Female | Chromosomes, Human, Pair 11 | Polymorphism, Single Nucleotide | Interleukin-10 Receptor beta Subunit - genetics | Chromosomes, Human, Pair 21 | Inflammatory Bowel Diseases - therapy | Genetic Linkage | Intestines | Inflammatory bowel diseases | Care and treatment | Interleukin-10 | Gene mutations | Analysis | Physiological aspects | Genetic aspects | Diagnosis | Health aspects | Inflammatory bowel disease | Proteins | Studies | Ostomy | Cytokines | Lymphocytes | Ear diseases | Immune system
INTESTINAL INFLAMMATION | MEDICINE, GENERAL & INTERNAL | CYTOKINE PRODUCTION | CROHNS-DISEASE | CRYSTAL-STRUCTURE | ULCERATIVE-COLITIS | AUTOSOMAL RECESSIVE ENTEROCOLITIS | SEQUENCE VARIANTS | LOCI CONTRIBUTE | IL-10 | GENOME-WIDE ASSOCIATION | Tumor Necrosis Factor-alpha - metabolism | Humans | Infant | Male | Mutation, Missense | Remission Induction | Sequence Analysis, DNA | Stem Cell Transplantation | Interleukin-10 Receptor alpha Subunit - chemistry | Interleukin-10 Receptor beta Subunit - chemistry | Interleukin-10 Receptor alpha Subunit - genetics | Pedigree | Age of Onset | Inflammatory Bowel Diseases - genetics | Interleukin-10 - metabolism | Female | Chromosomes, Human, Pair 11 | Polymorphism, Single Nucleotide | Interleukin-10 Receptor beta Subunit - genetics | Chromosomes, Human, Pair 21 | Inflammatory Bowel Diseases - therapy | Genetic Linkage | Intestines | Inflammatory bowel diseases | Care and treatment | Interleukin-10 | Gene mutations | Analysis | Physiological aspects | Genetic aspects | Diagnosis | Health aspects | Inflammatory bowel disease | Proteins | Studies | Ostomy | Cytokines | Lymphocytes | Ear diseases | Immune system
Journal Article
Gastroenterology, ISSN 0016-5085, 2012, Volume 143, Issue 2, pp. 347 - 355
Background & Aims Homozygous loss of function mutations in interleukin-10 ( IL10 ) and interleukin-10 receptors ( IL10R ) cause severe infantile (very early...
Gastroenterology and Hepatology | Genetic Defect | Children | Intestinal Inflammation | Immunodeficiency | COMPLETE REMISSION | BONE-MARROW-TRANSPLANTATION | RECEPTOR | PATHOGENESIS | REFRACTORY CROHNS-DISEASE | COLITIS | NON-HODGKINS-LYMPHOMA | LEUKEMIA | STEM-CELL TRANSPLANTATION | GASTROENTEROLOGY & HEPATOLOGY | GENOME-WIDE ASSOCIATION | Interleukin-10 - deficiency | Enzyme-Linked Immunosorbent Assay | Interleukin-10 Receptor beta Subunit - deficiency | Humans | Inflammatory Bowel Diseases - diagnosis | Hematopoietic Stem Cell Transplantation | Infant | Male | Treatment Outcome | Genetic Markers | Interleukin-10 Receptor alpha Subunit - deficiency | Sequence Analysis, DNA | Blotting, Western | Interleukin-10 Receptor alpha Subunit - genetics | Interleukin-10 - genetics | Inflammatory Bowel Diseases - genetics | Inflammatory Bowel Diseases - surgery | Female | Interleukin-10 Receptor beta Subunit - genetics | Mutation | Cohort Studies | Medical colleges | Interleukins | Gastrointestinal diseases | Stem cells | Transplantation | Health aspects | Mitogens | Hematopoietic stem cells | Tumors
Gastroenterology and Hepatology | Genetic Defect | Children | Intestinal Inflammation | Immunodeficiency | COMPLETE REMISSION | BONE-MARROW-TRANSPLANTATION | RECEPTOR | PATHOGENESIS | REFRACTORY CROHNS-DISEASE | COLITIS | NON-HODGKINS-LYMPHOMA | LEUKEMIA | STEM-CELL TRANSPLANTATION | GASTROENTEROLOGY & HEPATOLOGY | GENOME-WIDE ASSOCIATION | Interleukin-10 - deficiency | Enzyme-Linked Immunosorbent Assay | Interleukin-10 Receptor beta Subunit - deficiency | Humans | Inflammatory Bowel Diseases - diagnosis | Hematopoietic Stem Cell Transplantation | Infant | Male | Treatment Outcome | Genetic Markers | Interleukin-10 Receptor alpha Subunit - deficiency | Sequence Analysis, DNA | Blotting, Western | Interleukin-10 Receptor alpha Subunit - genetics | Interleukin-10 - genetics | Inflammatory Bowel Diseases - genetics | Inflammatory Bowel Diseases - surgery | Female | Interleukin-10 Receptor beta Subunit - genetics | Mutation | Cohort Studies | Medical colleges | Interleukins | Gastrointestinal diseases | Stem cells | Transplantation | Health aspects | Mitogens | Hematopoietic stem cells | Tumors
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2008, Volume 14, Issue 8, pp. 2405 - 2412
Purpose: Drug resistance is a major obstacle in cancer chemotherapy. Although the statistical probability of therapeutic success is known for larger patient...
Cluster analysis | Individualized cancer chemotherapy | Predictive assays | Drug resistance | Microarrays | Pharmacogenomics | SHORT-TERM TEST | CANCER-CHEMOTHERAPY | ONCOLOGY | SENSITIVITY | TRADITIONAL CHINESE MEDICINE | CASSETTE TRANSPORTER GENES | TETRAZOLIUM ASSAY | LEUKEMIA | MULTIDRUG-RESISTANCE | CELL-LINES | CYTOTOXICITY | Medicine, Chinese Traditional | Humans | Cell Line, Tumor | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Cell Proliferation - drug effects | ATP-Binding Cassette, Sub-Family B, Member 1 - physiology | Cluster Analysis | Neoplasms - drug therapy
Cluster analysis | Individualized cancer chemotherapy | Predictive assays | Drug resistance | Microarrays | Pharmacogenomics | SHORT-TERM TEST | CANCER-CHEMOTHERAPY | ONCOLOGY | SENSITIVITY | TRADITIONAL CHINESE MEDICINE | CASSETTE TRANSPORTER GENES | TETRAZOLIUM ASSAY | LEUKEMIA | MULTIDRUG-RESISTANCE | CELL-LINES | CYTOTOXICITY | Medicine, Chinese Traditional | Humans | Cell Line, Tumor | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Cell Proliferation - drug effects | ATP-Binding Cassette, Sub-Family B, Member 1 - physiology | Cluster Analysis | Neoplasms - drug therapy
Journal Article
Molecular Pharmacology, ISSN 0026-895X, 08/2003, Volume 64, Issue 2, pp. 382 - 394
A profound cytotoxic action of the antimalarial, artesunate (ART), was identified against 55 cancer cell lines of the U.S. National Cancer Institute (NCI). The...
GROWTH-FACTOR RECEPTOR | BREAST-CANCER CELLS | LEUKEMIC-CELLS | FALCIPARUM-MALARIA | HUMAN GLIOBLASTOMA CELLS | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | DRUG-RESISTANCE | EXPRESSION PROFILES | TETRAZOLIUM ASSAY | MULTIDRUG-RESISTANCE | Humans | Gene Expression Profiling | RNA, Messenger - metabolism | Cell Division - drug effects | Tumor Suppressor Protein p53 - physiology | Artemisinins - pharmacology | Animals | HL-60 Cells | Antineoplastic Agents - pharmacology | Sesquiterpenes - pharmacology | Tumor Cells, Cultured | Cell Cycle - drug effects | Drug Resistance, Multiple - physiology | Cell Line, Transformed | Apoptosis | Drug Screening Assays, Antitumor | RNA, Messenger - drug effects
GROWTH-FACTOR RECEPTOR | BREAST-CANCER CELLS | LEUKEMIC-CELLS | FALCIPARUM-MALARIA | HUMAN GLIOBLASTOMA CELLS | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | DRUG-RESISTANCE | EXPRESSION PROFILES | TETRAZOLIUM ASSAY | MULTIDRUG-RESISTANCE | Humans | Gene Expression Profiling | RNA, Messenger - metabolism | Cell Division - drug effects | Tumor Suppressor Protein p53 - physiology | Artemisinins - pharmacology | Animals | HL-60 Cells | Antineoplastic Agents - pharmacology | Sesquiterpenes - pharmacology | Tumor Cells, Cultured | Cell Cycle - drug effects | Drug Resistance, Multiple - physiology | Cell Line, Transformed | Apoptosis | Drug Screening Assays, Antitumor | RNA, Messenger - drug effects
Journal Article
Molecular Imaging and Biology, ISSN 1536-1632, 12/2019, Volume 21, Issue 6, pp. 1182 - 1191
The enzyme O6-methylguanine-DNA methyltransferase (MGMT) is an important component of the DNA repair machinery. MGMT removes O6-methylguanine from the DNA by...
rs12917 | Medicine & Public Health | MGMT | Deauville score | qPET | Imaging / Radiology | Pediatric Hodgkin lymphoma | [ 18 F]FDG-PET | Pediatrics | Biotechnology | Indication | Single-nucleotide polymorphism | Glucose | Homozygosity | Doxorubicin | DNA repair | Metabolic response | O6-methylguanine-DNA methyltransferase | Tomography | Deoxyribonucleic acid--DNA | Methylguanine | Positron emission | Etoposide | Fluorine isotopes | Prednisone | Radiation therapy | Metabolism | Patients | Vincristine | Lymphoma | Chemotherapy | Cell lines | Alleles | DNA methyltransferase | Lymphomas | Positron emission tomography | Hodgkin's disease | Polymorphism | Nucleotides
rs12917 | Medicine & Public Health | MGMT | Deauville score | qPET | Imaging / Radiology | Pediatric Hodgkin lymphoma | [ 18 F]FDG-PET | Pediatrics | Biotechnology | Indication | Single-nucleotide polymorphism | Glucose | Homozygosity | Doxorubicin | DNA repair | Metabolic response | O6-methylguanine-DNA methyltransferase | Tomography | Deoxyribonucleic acid--DNA | Methylguanine | Positron emission | Etoposide | Fluorine isotopes | Prednisone | Radiation therapy | Metabolism | Patients | Vincristine | Lymphoma | Chemotherapy | Cell lines | Alleles | DNA methyltransferase | Lymphomas | Positron emission tomography | Hodgkin's disease | Polymorphism | Nucleotides
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2006, Volume 12, Issue 14, pp. 4357 - 4363
Background: A major issue in the treatment of acute myeloid leukemia (AML) is resistance to chemotherapeutic drugs. Multidrug resistance can be caused by...
acute myeloid leukemia | ABC transporter | expression profiling | multi drug resistance | AML | INDUCTION THERAPY | TRANSPORTER GENES | ONCOLOGY | POOR PROGNOSTIC GROUP | IN-VIVO | MULTIDRUG-RESISTANCE | MRP3 | EXPRESSION | HUMAN TUMOR-CELLS | P-GLYCOPROTEIN | Oligonucleotide Array Sequence Analysis | Drug Resistance, Multiple | Jurkat Cells | Humans | Gene Expression Regulation, Neoplastic | Child, Preschool | Drug Resistance, Neoplasm | Male | ATP-Binding Cassette Transporters - physiology | Adolescent | ATP-Binding Cassette Transporters - metabolism | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Child | Bone Marrow Cells - metabolism | Cluster Analysis | Leukemia, Myeloid, Acute - genetics | RNA, Small Interfering - metabolism
acute myeloid leukemia | ABC transporter | expression profiling | multi drug resistance | AML | INDUCTION THERAPY | TRANSPORTER GENES | ONCOLOGY | POOR PROGNOSTIC GROUP | IN-VIVO | MULTIDRUG-RESISTANCE | MRP3 | EXPRESSION | HUMAN TUMOR-CELLS | P-GLYCOPROTEIN | Oligonucleotide Array Sequence Analysis | Drug Resistance, Multiple | Jurkat Cells | Humans | Gene Expression Regulation, Neoplastic | Child, Preschool | Drug Resistance, Neoplasm | Male | ATP-Binding Cassette Transporters - physiology | Adolescent | ATP-Binding Cassette Transporters - metabolism | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Child | Bone Marrow Cells - metabolism | Cluster Analysis | Leukemia, Myeloid, Acute - genetics | RNA, Small Interfering - metabolism
Journal Article
International journal of oncology, ISSN 1019-6439, 2001, Volume 18, Issue 4, pp. 767 - 773
Artesunate (ART) is a semi-synthetic derivative of artemisinin, the active principle of the Chinese herb Artemisia annua. ART reveals remarkable activity...
LEUKEMIC-CELLS | FALCIPARUM-MALARIA | DIVERSE PANEL | chemotherapy | Saccharomyces cerevisiae mutant strains | P-GLYCOPROTEIN | CLN2 | ONCOLOGY | PLASMODIUM-FALCIPARUM | BUB3 | drug resistance | TETRAZOLIUM ASSAY | ANTIMALARIAL DRUG | neoplasms | TUMOR-CELL-LINES | MULTIDRUG-RESISTANCE | ARTEMISININ | Neoplasms - metabolism | Saccharomyces cerevisiae - genetics | Humans | Cyclins - genetics | Drug Resistance, Neoplasm | Saccharomyces cerevisiae - drug effects | Saccharomyces cerevisiae - metabolism | Poly-ADP-Ribose Binding Proteins | Cyclins - drug effects | Artesunate | Cyclin G | Antineoplastic Agents - pharmacology | Cyclin G1 | Drug Screening Assays, Antitumor - methods | Tumor Cells, Cultured - drug effects | Leukemia - drug therapy | Cell Division - drug effects | Antimalarials - pharmacology | Neoplasms - drug therapy | Proteins - genetics | Artemisinins | Rhodamines | Saccharomyces cerevisiae Proteins | Proteins - drug effects | Sesquiterpenes - pharmacology | Cell Cycle Proteins | Fluorescent Dyes
LEUKEMIC-CELLS | FALCIPARUM-MALARIA | DIVERSE PANEL | chemotherapy | Saccharomyces cerevisiae mutant strains | P-GLYCOPROTEIN | CLN2 | ONCOLOGY | PLASMODIUM-FALCIPARUM | BUB3 | drug resistance | TETRAZOLIUM ASSAY | ANTIMALARIAL DRUG | neoplasms | TUMOR-CELL-LINES | MULTIDRUG-RESISTANCE | ARTEMISININ | Neoplasms - metabolism | Saccharomyces cerevisiae - genetics | Humans | Cyclins - genetics | Drug Resistance, Neoplasm | Saccharomyces cerevisiae - drug effects | Saccharomyces cerevisiae - metabolism | Poly-ADP-Ribose Binding Proteins | Cyclins - drug effects | Artesunate | Cyclin G | Antineoplastic Agents - pharmacology | Cyclin G1 | Drug Screening Assays, Antitumor - methods | Tumor Cells, Cultured - drug effects | Leukemia - drug therapy | Cell Division - drug effects | Antimalarials - pharmacology | Neoplasms - drug therapy | Proteins - genetics | Artemisinins | Rhodamines | Saccharomyces cerevisiae Proteins | Proteins - drug effects | Sesquiterpenes - pharmacology | Cell Cycle Proteins | Fluorescent Dyes
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 2804 - 2804
Background HD is a B-lineage lymphoma characterized, depending on subtype, by a prominent inflammatory infiltrate and fibrosis. Clinically, inflammatory...
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 9, p. e23955
Background: We determined antibodies to the pandemic influenza A (H1N1) 2009 virus in children to assess: the incidence of (H1N1) 2009 infections in the...
HEMAGGLUTINATION INHIBITION | ANTIBODY | RISK | PREVALENCE | MULTIDISCIPLINARY SCIENCES | VACCINE | Influenza A Virus, H1N1 Subtype - immunology | Age Distribution | Humans | Child, Preschool | Infant | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - epidemiology | Male | Seroepidemiologic Studies | Germany - epidemiology | Influenza Vaccines - immunology | Adolescent | Female | Child | Immunization | Pandemics | Vaccination | Antibodies | Viruses | Infections | Vaccines | Hemagglutination inhibition | Incidence | Hemagglutination | Infectious diseases | Swine flu | Swine | Influenza | Livestock | Children
HEMAGGLUTINATION INHIBITION | ANTIBODY | RISK | PREVALENCE | MULTIDISCIPLINARY SCIENCES | VACCINE | Influenza A Virus, H1N1 Subtype - immunology | Age Distribution | Humans | Child, Preschool | Infant | Influenza A Virus, H1N1 Subtype - pathogenicity | Influenza, Human - epidemiology | Male | Seroepidemiologic Studies | Germany - epidemiology | Influenza Vaccines - immunology | Adolescent | Female | Child | Immunization | Pandemics | Vaccination | Antibodies | Viruses | Infections | Vaccines | Hemagglutination inhibition | Incidence | Hemagglutination | Infectious diseases | Swine flu | Swine | Influenza | Livestock | Children
Journal Article
Haematologica, ISSN 0390-6078, 03/2019, Volume 104, Issue 4, pp. 756 - 765
Thromboembolism is a serious complication of induction therapy for childhood acute lymphoblastic leukemia. We prospectively compared the efficacy and safety of...
CENTRAL VENOUS LINE | PROPHYLACTIC THERAPY | METAANALYSIS | L-ASPARAGINASE TREATMENT | AIEOP-BFM | PEDIATRIC-PATIENTS | DISEASE | RISK | COMPLICATIONS | THROMBOEMBOLISM | HEMATOLOGY
CENTRAL VENOUS LINE | PROPHYLACTIC THERAPY | METAANALYSIS | L-ASPARAGINASE TREATMENT | AIEOP-BFM | PEDIATRIC-PATIENTS | DISEASE | RISK | COMPLICATIONS | THROMBOEMBOLISM | HEMATOLOGY
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 08/2006, Volume 5, Issue 8, pp. 1986 - 1994
A major issue in the treatment of T-cell acute lymphoblastic leukemia (T-ALL) is resistance to chemotherapeutic drugs. Multidrug resistance can be caused by...
multidrug resistance | acute lymphoblastic leukemia | ABC transporter | expression profiling | DE-NOVO | PROGNOSTIC-FACTOR | GENE | ONCOLOGY | P-GLYCOPROTEIN EXPRESSION | RESISTANCE-ASSOCIATED PROTEIN | ACUTE MYELOID-LEUKEMIA | DRUG-RESISTANCE | TETRAZOLIUM ASSAY | MULTIDRUG-RESISTANCE | HUMAN TUMOR-CELLS | Models, Theoretical | Leukemia-Lymphoma, Adult T-Cell - genetics | Down-Regulation | Humans | Child, Preschool | Male | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Drug Resistance, Neoplasm - genetics | Leukemia-Lymphoma, Adult T-Cell - drug therapy | ATP-Binding Cassette Transporters - genetics | RNA Interference | ATP-Binding Cassette Transporters - drug effects | Adolescent | Female | Multidrug Resistance-Associated Proteins - genetics | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Child
multidrug resistance | acute lymphoblastic leukemia | ABC transporter | expression profiling | DE-NOVO | PROGNOSTIC-FACTOR | GENE | ONCOLOGY | P-GLYCOPROTEIN EXPRESSION | RESISTANCE-ASSOCIATED PROTEIN | ACUTE MYELOID-LEUKEMIA | DRUG-RESISTANCE | TETRAZOLIUM ASSAY | MULTIDRUG-RESISTANCE | HUMAN TUMOR-CELLS | Models, Theoretical | Leukemia-Lymphoma, Adult T-Cell - genetics | Down-Regulation | Humans | Child, Preschool | Male | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Drug Resistance, Neoplasm - genetics | Leukemia-Lymphoma, Adult T-Cell - drug therapy | ATP-Binding Cassette Transporters - genetics | RNA Interference | ATP-Binding Cassette Transporters - drug effects | Adolescent | Female | Multidrug Resistance-Associated Proteins - genetics | Antineoplastic Agents - pharmacology | Tumor Cells, Cultured | Child
Journal Article
Journal of Physics B: Atomic, Molecular and Optical Physics, ISSN 0953-4075, 12/2014, Volume 47, Issue 23, pp. 234011 - 21
We present a fully analytic model of an all-optical free electron laser (OFEL) undulator based on the Traveling-Wave Thomson-Scattering (TWTS) scheme. The TWTS...
laser undulator | Travelling-Wave Thomson Scattering | x-ray | optical FEL | EUV | COMPRESSOR | BEAMS | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | PULSES | UNDULATORS | PLASMA ACCELERATOR | WAKEFIELD ACCELERATOR | SOURCE DRIVEN | FEMTOSECOND | OPTICS | LITHOGRAPHY | Lasers | Free electron lasers | Mathematical analysis | Automotive industry | Mathematical models | Electron sources | Automobiles | Automotive components | Automotive engineering
laser undulator | Travelling-Wave Thomson Scattering | x-ray | optical FEL | EUV | COMPRESSOR | BEAMS | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | PULSES | UNDULATORS | PLASMA ACCELERATOR | WAKEFIELD ACCELERATOR | SOURCE DRIVEN | FEMTOSECOND | OPTICS | LITHOGRAPHY | Lasers | Free electron lasers | Mathematical analysis | Automotive industry | Mathematical models | Electron sources | Automobiles | Automotive components | Automotive engineering
Journal Article
Leukemia, ISSN 0887-6924, 08/2019
We used hybrid capture-targeted next-generation sequencing of circulating cell-free DNA (ccfDNA) of pediatric Hodgkin lymphoma (PHL) patients to determine...
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 03/2003, Volume 9, Issue 3, pp. 1083 - 1086
Purpose: The family of multidrug resistance-associated proteins (MRPs) belongs to the ATP-binding cassette superfamily of transporters, which have the ability...
LUNG-CANCER | AML-BFM-93 | SOUTHWEST-ONCOLOGY-GROUP | INDUCTION THERAPY | MESSENGER-RNA | ONCOLOGY | TRANSPORTERS | POOR RESPONSE | IN-VIVO | DRUG-RESISTANCE | P-GLYCOPROTEIN | Recurrence | Humans | Leukemia, Myeloid, Acute - metabolism | Ribosomal Proteins - biosynthesis | Male | Treatment Outcome | Mitochondrial Proteins | Multidrug Resistance-Associated Proteins - biosynthesis | Reverse Transcriptase Polymerase Chain Reaction | Biomarkers, Tumor | Remission Induction | Leukemia, Myeloid, Acute - mortality | Time Factors | Adolescent | Saccharomyces cerevisiae Proteins | Female | Child | Leukemia, Myeloid, Acute - therapy
LUNG-CANCER | AML-BFM-93 | SOUTHWEST-ONCOLOGY-GROUP | INDUCTION THERAPY | MESSENGER-RNA | ONCOLOGY | TRANSPORTERS | POOR RESPONSE | IN-VIVO | DRUG-RESISTANCE | P-GLYCOPROTEIN | Recurrence | Humans | Leukemia, Myeloid, Acute - metabolism | Ribosomal Proteins - biosynthesis | Male | Treatment Outcome | Mitochondrial Proteins | Multidrug Resistance-Associated Proteins - biosynthesis | Reverse Transcriptase Polymerase Chain Reaction | Biomarkers, Tumor | Remission Induction | Leukemia, Myeloid, Acute - mortality | Time Factors | Adolescent | Saccharomyces cerevisiae Proteins | Female | Child | Leukemia, Myeloid, Acute - therapy
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 11/2001, Volume 7, Issue 11, pp. 3381 - 3384
Purpose: Overexpression of vascular endothelial growth factor (VEGF) is associated with increased angiogenesis, growth, and metastasis in solid tumors, but to...
ACUTE MYELOID-LEUKEMIA | ANGIOGENESIS | ONCOLOGY | EXPRESSION | CANCER | VEGF | Vascular Endothelial Growth Factor A | Vascular Endothelial Growth Factors | Humans | Gene Expression Regulation, Neoplastic | Neoplasm Recurrence, Local | Child, Preschool | Infant | Male | RNA, Neoplasm - metabolism | Polymerase Chain Reaction - methods | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Lymphokines - genetics | Endothelial Growth Factors - genetics | Adolescent | Survival Analysis | RNA, Neoplasm - genetics | Female | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Child
ACUTE MYELOID-LEUKEMIA | ANGIOGENESIS | ONCOLOGY | EXPRESSION | CANCER | VEGF | Vascular Endothelial Growth Factor A | Vascular Endothelial Growth Factors | Humans | Gene Expression Regulation, Neoplastic | Neoplasm Recurrence, Local | Child, Preschool | Infant | Male | RNA, Neoplasm - metabolism | Polymerase Chain Reaction - methods | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Lymphokines - genetics | Endothelial Growth Factors - genetics | Adolescent | Survival Analysis | RNA, Neoplasm - genetics | Female | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Child
Journal Article
Pediatric Infectious Disease Journal, ISSN 0891-3668, 10/2013, Volume 33, Issue 3, pp. 258 - 262
Background: Since asymptomatic hepatitis E virus (HEV) infections particularly affect children, there is a need for studies to determine the HEV seroprevalence...
INFECTIOUS DISEASES | children | hepatitis E | seroprevalence | PEDIATRICS | INFECTION | AGREEMENT | IMMUNOLOGY | zoonosis | Prevalence | Enzyme-Linked Immunosorbent Assay | Humans | Child, Preschool | Infant | Male | Seroepidemiologic Studies | Antibodies, Viral - blood | Germany - epidemiology | Hepatitis E - epidemiology | Animals | Hepatitis E virus - immunology | Adolescent | Hepatitis E - immunology | Female | Child | Infant, Newborn
INFECTIOUS DISEASES | children | hepatitis E | seroprevalence | PEDIATRICS | INFECTION | AGREEMENT | IMMUNOLOGY | zoonosis | Prevalence | Enzyme-Linked Immunosorbent Assay | Humans | Child, Preschool | Infant | Male | Seroepidemiologic Studies | Antibodies, Viral - blood | Germany - epidemiology | Hepatitis E - epidemiology | Animals | Hepatitis E virus - immunology | Adolescent | Hepatitis E - immunology | Female | Child | Infant, Newborn
Journal Article
British Journal of Haematology, ISSN 0007-1048, 07/2002, Volume 118, Issue 1, pp. 147 - 150
The breast cancer resistance protein (BCRP), also known as mitoxantrone resistance protein (MXR) or placenta ABC protein (ABC-P), is the second member of the...
BCRP | multidrug resistance | ALL | prognosis | Prognosis | Multidrug resistance | MITOXANTRONE | MEMBRANE | BCRP/MXR/ABCP | CELL-LINES | OVEREXPRESSION | TRANSPORTER GENE | TOPOTECAN | LEUKEMIA | MULTIDRUG-RESISTANCE | HEMATOLOGY | CANCER RESISTANCE PROTEIN | Leukocytes, Mononuclear - metabolism | Oncogene Proteins - genetics | Recurrence | Gene Expression | Humans | Child, Preschool | Infant | Male | Proto-Oncogene Proteins c-bcr | Case-Control Studies | Polymerase Chain Reaction - methods | Disease-Free Survival | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Adolescent | Adult | Female | Proto-Oncogene Proteins | Retrospective Studies | Protein-Tyrosine Kinases | Child
BCRP | multidrug resistance | ALL | prognosis | Prognosis | Multidrug resistance | MITOXANTRONE | MEMBRANE | BCRP/MXR/ABCP | CELL-LINES | OVEREXPRESSION | TRANSPORTER GENE | TOPOTECAN | LEUKEMIA | MULTIDRUG-RESISTANCE | HEMATOLOGY | CANCER RESISTANCE PROTEIN | Leukocytes, Mononuclear - metabolism | Oncogene Proteins - genetics | Recurrence | Gene Expression | Humans | Child, Preschool | Infant | Male | Proto-Oncogene Proteins c-bcr | Case-Control Studies | Polymerase Chain Reaction - methods | Disease-Free Survival | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Adolescent | Adult | Female | Proto-Oncogene Proteins | Retrospective Studies | Protein-Tyrosine Kinases | Child
Journal Article