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CANCER RESEARCH, ISSN 0008-5472, 09/2019, Volume 79, Issue 18, pp. 4744 - 4753
Although the use of ATP-competitive tyrosine kinase inhibitors of oncoprotein BCR-ABL1 has enabled durable responses in patients with chronic myeloid leukemia... 
TRANSFORMATION | SITE | AUTOINHIBITION | STEM-CELLS | INHIBITION | ONCOLOGY | BCR-ABL | KINASE | IMATINIB | MECHANISMS | MOLECULES
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 4248 - 4248
Abstract Chronic myeloid leukemia (CML) is caused by the oncogenic tyrosine kinase BCR-ABL1, which is uniquely present in the leukemic cells and drives... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 836 - 836
Abstract Introduction: Translating the genetic and epigenetic heterogeneity underlying human cancers into therapeutic strategies represents an ongoing... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 2747 - 2747
Abstract The successful design and application of ABL1 tyrosine kinase inhibitors for the treatment of chronic myeloid leukemia (CML) has become a paradigm for... 
Journal Article
Blood, ISSN 0006-4971, 12/2015, Volume 126, Issue 23, pp. 2461 - 2461
Abstract The success of the ABL1 tyrosine kinase inhibitor imatinib in the treatment of chronic myeloid leukemia (CML) set a precedent for molecularly targeted... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 1119 - 1119
Abstract Despite the well-established success of ABL1 tyrosine kinase inhibitors (TKIs) in the treatment of patients with chronic myeloid leukemia (CML),... 
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 4514 - 4514
Abstract The advent of ABL1 tyrosine kinase inhibitors has radically transformed the treatment and outcomes for patients with chronic myeloid leukemia (CML).... 
Journal Article
Blood, ISSN 0006-4971, 11/2013, Volume 122, Issue 21, pp. 3994 - 3994
Abstract Despite the impressive success of imatinib in chronic myeloid leukemia (CML), resistance to therapy remains an issue for approximately 15-20% of newly... 
Journal Article
by Tyner, Jeffrey W and Tognon, Cristina E and Bottomly, Daniel and Wilmot, Beth and Kurtz, Stephen E and Savage, Samantha L and Long, Nicola and Schultz, Anna Reister and Traer, Elie and Abel, Melissa and Agarwal, Anupriya and Blucher, Aurora and Borate, Uma and Bryant, Jade and Burke, Russell and Carlos, Amy and Carpenter, Richie and Carroll, Joseph and Chang, Bill H and Coblentz, Cody and d’Almeida, Amanda and Cook, Rachel and Danilov, Alexey and Dao, Kim-Hien T and Degnin, Michie and Devine, Deirdre and Dibb, James and Edwards, David K and Eide, Christopher A and English, Isabel and Glover, Jason and Henson, Rachel and Ho, Hibery and Jemal, Abdusebur and Johnson, Kara and Johnson, Ryan and Junio, Brian and Kaempf, Andy and Leonard, Jessica and Lin, Chenwei and Liu, Selina Qiuying and Lo, Pierrette and Loriaux, Marc M and Luty, Samuel and Macey, Tara and MacManiman, Jason and Martinez, Jacqueline and Mori, Motomi and Nelson, Dylan and Nichols, Ceilidh and Peters, Jill and Ramsdill, Justin and Rofelty, Angela and Schuff, Robert and Searles, Robert and Segerdell, Erik and Smith, Rebecca L and Spurgeon, Stephen E and Sweeney, Tyler and Thapa, Aashis and Visser, Corinne and Wagner, Jake and Watanabe-Smith, Kevin and Werth, Kristen and Wolf, Joelle and White, Libbey and Yates, Amy and Zhang, Haijiao and Cogle, Christopher R and Collins, Robert H and Connolly, Denise C and Deininger, Michael W and Drusbosky, Leylah and Hourigan, Christopher S and Jordan, Craig T and Kropf, Patricia and Lin, Tara L and Martinez, Micaela E and Medeiros, Bruno C and Pallapati, Rachel R and Pollyea, Daniel A and Swords, Ronan T and Watts, Justin M and Weir, Scott J and Wiest, David L and Winters, Ryan M and McWeeney, Shannon K and Druker, Brian J
Nature, ISSN 0028-0836, 10/2018, Volume 562, Issue 7728, pp. 526 - 531
Journal Article
by Burton, Paul R and Clayton, David G and Cardon, Lon R and Craddock, Nick and Deloukas, Panos and Duncanson, Audrey and Kwiatkowski, Dominic P and McCarthy, Mark I and Ouwehand, Willem H and Samani, Nilesh J and Todd, John A and Donnelly, Peter and Barrett, Jeffrey C and Davison, Dan and Easton, Doug and Evans, David M and Leung, Hin-Tak and Marchini, Jonathan L and Morris, Andrew P and Spencer, Chris C.A and Tobin, Martin D and Attwood, Antony P and Boorman, James P and Cant, Barbara and Everson, Ursula and Hussey, Judith M and Jolley, Jennifer D and Knight, Alexandra S and Koch, Kerstin and Meech, Elizabeth and Nutland, Sarah and Prowse, Christopher V and Stevens, Helen E and Taylor, Niall C and Walters, Graham R and Walker, Neil M and Watkins, Nicholas A and Winzer, Thilo and Jones, Richard W and McArdle, Wendy L and Ring, Susan M and Strachan, David P and Pembrey, Marcus and Breen, Gerome and Clair, David St and Caesar, Sian and Gordon-Smith, Katharine and Jones, Lisa and Fraser, Christine and Green, Elaine K and Grozeva, Detelina and Hamshere, Marian L and Holmans, Peter A and Jones, Ian R and Kirov, George and Moskivina, Valentina and Nikolov, Ivan and O'Donovan, Michael C and Owen, Michael J and Collier, David A and Elkin, Amanda and Farmer, Anne and Williamson, Richard and McGuffin, Peter and Young, Allan H and Ferrier, I. Nicol and Ball, Stephen G and Balmforth, Anthony J and Barrett, Jennifer H and Bishop, Timothy D and Iles, Mark M and Maqbool, Azhar and Yuldasheva, Nadira and Hall, Alistair S and Braund, Peter S and Dixon, Richard J and Mangino, Massimo and Stevens, Suzanne and Thompson, John R and Bredin, Francesca and Tremelling, Mark and Parkes, Miles and Drummond, Hazel and Lees, Charles W and Nimmo, Elaine R and Satsangi, Jack and Fisher, Sheila A and Forbes, Alastair and Lewis, Cathryn M and Onnie, Clive M and Prescott, Natalie J and Sanderson, Jeremy and Matthew, Christopher G and Barbour, Jamie and Mohiuddin, M. Khalid and Todhunter, Catherine E and Mansfield, John C and Ahmad, Tariq and Cummings, Fraser R and Jewell, Derek P and ... and Breast Cancer Susceptibility Collaboration (UK) and Wellcome Trust Case Control Consortium and Biologics in RA Genetics and Genomics Study Syndicate (BRAGGS) Steering Committee and Australo-Anglo-American Spondylitis Consortium (TASC) and The Australo-Anglo-American Spondylitis Consortium (TASC)
Nature Genetics, ISSN 1061-4036, 11/2007, Volume 39, Issue 11, pp. 1329 - 1337
Journal Article
by Hudson, Lawrence N and Newbold, Tim and Contu, Sara and Hill, Samantha L L and Lysenko, Igor and De Palma, Aiana and Phillips, Helen R P and Alhusseini, Tamera I and Bedford, Felicity E and Bennett, Dominic J and Booth, Hollie and Burton, Victoria J and Chng, Charlotte W T and Choimes, Argyrios and Correia, David L P and Day, Julie and Echeverría-Londoño, Susy and Emerson, Susan R and Gao, Di and Garon, Morgan and Harrison, Michelle L K and Ingram, Daniel J and Jung, Martin and Kemp, Victoria and Kirkpatrick, Lucinda and Martin, Callum D and Pan, Yuan and Pask-Hale, Gwilym D and Pynegar, Edwin L and Robinson, Alexana N and Sanchez-Ortiz, Katia and Senior, Rebecca A and Simmons, Benno I and White, Hannah J and Zhang, Hanbin and Aben, Job and Abrahamczyk, Stefan and Adum, Gilbert B and Aguilar-Barquero, Virginia and Aizen, Marcelo A and Albertos, Belén and Alcala, E L and Del Mar Alguacil, Maria and Alignier, Auey and Ancrenaz, Marc and Andersen, Alan N and Arbeláez-Cortés, Enrique and Armbrecht, Inge and Arroyo-Roíguez, Víctor and Aumann, Tom and Axmacher, Jan C and Azhar, Baul and Azpiroz, Aián B and Baeten, Lander and Bakayoko, Adama and Báldi, Anás and Banks, John E and Baral, Sharad K and Barlow, Jos and Barratt, Barbara I P and Barrico, Lurdes and Bartolommei, Paola and Barton, Diane M and Basset, Yves and Batáry, Péter and Bates, Adam J and Baur, Bruno and Bayne, Erin M and Beja, Peo and Benedick, Suzan and Berg, Åke and Bernard, Henry and Berry, Nicholas J and Bhatt, Dinesh and Bicknell, Jake E and Bihn, Jochen H and Blake, Robin J and Bobo, Kadiri S and Bóçon, Roberto and Boekhout, Teun and Böhning-Gaese, Katrin and Bonham, Kevin J and Borges, Paulo A V and Borges, Sérgio H and Boutin, Céline and Bouyer, Jérémy and Bragagnolo, Cibele and Brandt, Jodi S and Brearley, Francis Q and Brito, Isabel and Bros, Vicenç and Brunet, Jörg and Buczkowski, Grzegorz and Buddle, Christopher M and Bugter, Rob and Buscardo, Erika and Buse, Jörn and Cabra-García, Jimmy and Cáceres, Nilton C and Cagle, Nicolette L and ... and Stockholms universitet and Institutionen för ekologi, miljö och botanik and Naturvetenskapliga fakulteten
Ecology and Evolution, ISSN 2045-7758, 01/2017, Volume 7, Issue 1, pp. 145 - 188
The PREDICTS project-Projecting Responses of Ecological Diversity In Changing Terrestrial Systems (www.predicts.org.uk)-has collated from published studies a... 
global biodiversity modeling | land use | global change | data sharing | habitat destruction | FRUIT-FEEDING BUTTERFLIES | TROPICAL DRY FOREST | LOWLAND DIPTEROCARP FOREST | BEES HYMENOPTERA APIDAE | PLANT COMMUNITY COMPOSITION | BIRD SPECIES RICHNESS | EVOLUTIONARY BIOLOGY | BOMBUS SPP. HYMENOPTERA | LAND-USE CHANGE | ECOLOGY | CARABID BEETLE ASSEMBLAGES | BUMBLEBEE NEST DENSITY | Data bases | Biological diversity | Geography | Statistical analysis | Ecosystems | Extinction | Human influences | Terrestrial environments | Spatial analysis | Metadata | Regional development | Ecology | Statistical methods | Research | Biodiversity | Land use | Datasets | Endangered & extinct species | Databases | Statistical models | Councils | Mathematical models | Trends | Ecology: 488 | VDP | Zoology and botany: 480 | Zoologiske og botaniske fag: 480 | Matematikk og Naturvitenskap: 400 | Mathematics and natural science: 400 | Økologi: 488 | Ecological heterogeneity | Heterogeneïtat ecològica | Biodiversitat | Bases de dades | Biodiversity and Ecology | Environmental Sciences | Global Changes | Biological Sciences | Geovetenskap och miljövetenskap | Naturvetenskap | Biologiska vetenskaper | Natural Sciences | Ekologi | Earth and Related Environmental Sciences | Alterra - Biodiversity and policy | Biodiversity and Policy | Biodiversiteit en Beleid | Alterra - Biodiversiteit en beleid
Journal Article