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Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P704 - P705
Journal Article
Proceedings of the National Academy of Sciences of the United States, ISSN 0027-8424, 09/2018, Volume 115, Issue 36, p. 9032
The blood-aqueous barrier plays a key role in regulating aqueous humor homeostasis by selectively restricting passage of proteins into the eye. The kinetics of... 
Eye | Homeostasis | Physiological aspects | Observations | Mass spectrometry | Methods
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2018, Volume 115, Issue 36, p. 9032
The blood-aqueous barrier plays a key role in regulating aqueous humor homeostasis by selectively restricting passage of proteins into the eye. The kinetics of... 
Regulators | Cornea | Nitrogen 15 | Homeostasis | Retina | Nitrogen isotopes | Serum proteins | Blood | Vascularization | Proteins | Macular degeneration | Eye | Plasma proteins | Eye injuries | Stable isotopes | Eye (anatomy) | Age | Leakage | Spectroscopy | Wound healing | Blood vessels | Mass spectroscopy | Permeability | Nitrogen | Eyes & eyesight | Barriers | Proteomics | Kinetics | Mass spectrometry
Journal Article
SCIENCE, ISSN 0036-8075, 09/2017, Volume 357, Issue 6357, pp. 1255 - 1255
Mitochondrial and lysosomal dysfunction have been implicated in substantia nigra dopaminergic neurodegeneration in Parkinson's disease (PD), but how these... 
GLUCOCEREBROSIDASE | PACEMAKING | DJ-1 | ALPHA-SYNUCLEIN | SUBSTANTIA-NIGRA | MULTIDISCIPLINARY SCIENCES | Mitochondria - enzymology | Mesencephalon - metabolism | Humans | Protein Deglycase DJ-1 - genetics | Substantia Nigra - metabolism | Melanins - metabolism | Glucosylceramidase - deficiency | Lysosomes - metabolism | Dopaminergic Neurons - metabolism | Tacrolimus - pharmacology | Parkinson Disease - metabolism | Dopamine - metabolism | Disease Models, Animal | Substantia Nigra - enzymology | Cell Line | Calcineurin Inhibitors - pharmacology | Oxidation-Reduction | Mesencephalon - enzymology | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Parkinson Disease - genetics | Mice, Knockout | Animals | Parkinson Disease - enzymology | Mice | Oxidative Stress - drug effects | alpha-Synuclein - metabolism | Oxidation-reduction reaction | Development and progression | Mitochondria | Dopamine | Parkinson's disease | Health aspects | Brain | Energy metabolism | Animal models | Target recognition | Mesencephalon | Pathogenesis | Substantia nigra | Parkinsons disease | Lysosomes | Synuclein | Accumulation | Pathways | Enzymatic activity | Neurodegeneration | Rodents | Oxidation | Degeneration | Species | Movement disorders | Dopamine receptors | Neurodegenerative diseases | Neurons | Medical treatment | Metabolism | Patients | Glucosylceramidase | Index Medicus
Journal Article
Science, ISSN 0036-8075, 09/2017, Volume 357, Issue 6357, pp. 1255 - 1261
Mitochondrial and lysosomal dysfunction have been implicated in substantia nigra dopaminergic neurodegeneration in Parkinson’s disease (PD), but how these... 
Journal Article
Science, ISSN 0036-8075, 2/2012, Volume 335, Issue 6071, pp. 942 - 942
Journal Article
Science (Washington), ISSN 0036-8075, 02/2012, Volume 335, Issue 6071, pp. 942 - 942
To combat the functional decline of the proteome, cells use the process of protein turnover to replace potentially impaired polypeptides with new functional... 
Age
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2012, Volume 18, Issue 1, pp. 159 - 165
Journal Article
Neuron, ISSN 0896-6273, 03/2012, Volume 73, Issue 5, pp. 903 - 910
Latrophilins (LPHNs) are a small family of G protein-coupled receptors known to mediate the massive synaptic exocytosis caused by the black widow spider venom... 
EXOCYTOSIS | RICH REPEAT PROTEINS | INTERACTS | SUSCEPTIBILITY | COUPLED RECEPTORS | NEURAL CIRCUITS | CELL-ADHESION | DIFFERENTIATION | ALPHA-LATROTOXIN RECEPTOR | NEUROSCIENCES | FAMILY | Disks Large Homolog 4 Protein | Surface Plasmon Resonance | Brain | RNA, Small Interfering - genetics | Electric Stimulation | Receptors, G-Protein-Coupled - metabolism | Embryo, Mammalian | Coculture Techniques | Humans | Rats, Long-Evans | Green Fluorescent Proteins - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Synapses - genetics | RNA, Messenger - metabolism | Excitatory Postsynaptic Potentials - genetics | Gene Expression Regulation, Developmental - physiology | Synaptophysin - metabolism | Animals, Newborn | Glutamic Acid - pharmacology | Membrane Proteins - genetics | Rats | Mutation - genetics | Patch-Clamp Techniques | Analysis of Variance | Mice | Receptors, G-Protein-Coupled - genetics | RNA, Small Interfering - metabolism | Receptors, Peptide - metabolism | Gene Expression Regulation, Developmental - genetics | Neurons - cytology | Chromatography, High Pressure Liquid | Cerebral Cortex - cytology | Receptors, Peptide - genetics | Dose-Response Relationship, Drug | Excitatory Postsynaptic Potentials - physiology | Transfection | Mass Spectrometry | Membrane Proteins - pharmacokinetics | Female | Membrane Proteins - metabolism | Green Fluorescent Proteins - metabolism | Synapses - physiology | Cells, Cultured | Electroporation | Hippocampus - cytology | Pregnancy | Animals | Protein Binding | Glutamic Acid - metabolism | Subcellular Fractions | Proteins | Neurosciences | Neurons | Venom | Physiological aspects | Mass spectrometry | Chromatography | Membrane proteins | Attention deficit disorder | Ligands | Mutation
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 07/2011, Volume 36, Issue 7, p. 388
Cellular membranes are composed of proteins and glyco- and phospholipids and play an indispensible role in maintaining cellular integrity and homeostasis, by... 
Proteins | Membranes | Proteomics | Homeostasis | Mass spectrometry
Journal Article
Neuron, ISSN 0896-6273, 12/2009, Volume 64, Issue 6, pp. 799 - 806
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 8, pp. 2700 - 2700
Journal Article
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 04/2018, pp. 1 - 16
Sensory perturbations in visual, auditory and tactile perception are core problems in fragile X syndrome (FXS). In the Fmr1 knockout mouse model of FXS, the... 
Journal Article