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1. Full Text Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration
by Mandai, Michiko and Watanabe, Akira and Kurimoto, Yasuo and Hirami, Yasuhiko and Morinaga, Chikako and Daimon, Takashi and Fujihara, Masashi and Akimaru, Hiroshi and Sakai, Noriko and Shibata, Yumiko and Terada, Motoki and Nomiya, Yui and Tanishima, Shigeki and Nakamura, Masahiro and Kamao, Hiroyuki and Sugita, Sunao and Onishi, Akishi and Ito, Tomoko and Fujita, Kanako and Kawamata, Shin and Go, Masahiro J and Shinohara, Chikara and Hata, Ken-ichiro and Sawada, Masanori and Yamamoto, Midori and Ohta, Sachiko and Ohara, Yasuo and Yoshida, Kenichi and Kuwahara, Junko and Kitano, Yuko and Amano, Naoki and Umekage, Masafumi and Kitaoka, Fumiyo and Tanaka, Azusa and Okada, Chihiro and Takasu, Naoko and Ogawa, Seishi and Yamanaka, Shinya and Takahashi, Masayo
The New England Journal of Medicine, ISSN 0028-4793, 03/2017, Volume 376, Issue 11, pp. 1038 - 1046
A goal of regenerative medicine is to use induced pluripotent stem cells to generate an autologous graft for transplantation. This study tests the feasibility... 
SURGERY | TRANSLOCATION | MEDICINE, GENERAL & INTERNAL | AGE-RELATED MACULOPATHY | PIGMENT EPITHELIUM | RPE | PREVALENCE | RANIBIZUMAB | SHEETS | TRANSPLANTATION | Retinal Pigment Epithelium - transplantation | Humans | Male | Transplantation, Autologous | Feasibility Studies | Macular Degeneration - therapy | Fibroblasts | Female | Aged | Cell Differentiation | Cell Culture Techniques | Induced Pluripotent Stem Cells - cytology | Retinal Pigment Epithelium - cytology | Macular degeneration | Retinal ganglion cells | Usage | Care and treatment | Edema | Autografts | Biomedical research | Research & development--R&D | Developmental biology | Clinical trials | Retina | Transplantation | Genomes | Grants | Acuity | Studies | Regeneration | Hospitals | Surgery | Stem cells | Photoreceptors | Skin | Vascular endothelial growth factor | Age | Pluripotency | Inhibitory postsynaptic potentials
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2. Full Text Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial
by Abe, Koji and Aoki, Masashi and Tsuji, Shoji and Itoyama, Yasuto and Sobue, Gen and Togo, Masanori and Hamada, Chikuma and Tanaka, Masahiko and Akimoto, Makoto and Nakamura, Kazue and Takahashi, Yuji and Takahashi, Fumihiro and Kondo, Kazuoki and Yoshino, Hiide and Sasaki, Kouichi and Sasaki, Hidenao and Yabe, Ichiro and Doi, Shizuki and Warita, Hitoshi and Imai, Takashi and Ito, Hiroaki and Ito, Kimiko and Fukuchi, Mitsumasa and Osumi, Etsuko and Wada, Manabu and Nakano, Imaharu and Morita, Mitsuya and Ogata, Katsuhisa and Maruki, Yuichi and Kano, Osamu and Yamazaki, Mineo and Ishiura, Hiroyuki and Ogino, Mieko and Koike, Ryoko and Ishida, Chiho and Uchiyama, Tsuyoshi and Mizoguchi, Kouichi and Obi, Tomokazu and Watanabe, Hirohisa and Atsuta, Naoki and Aiba, Ikuko and Taniguchi, Akira and Sawada, Hideyuki and Hazama, Takanori and Fujimura, Harutoshi and Kusaka, Hirofumi and Kunieda, Takenobu and Kikuchi, Hitoshi and Matsuo, Hidenori and Ueyama, Hidetsugu and Uekawa, Kazutoshi and Ueda, Masaki and Murakami, Aiko and Sumii, Rie and Kudou, Takuya and Morimoto, Kazunori and Yoneoka, Takatomo and Hirai, Manabu and Terai, Hidetomo and Natori, Tomoko and Matsui, Hiroshi and Kotani, Kuniko and Yoshida, Kaori and Iwasaki, Tomohisa and Edaravone MCI-186 ALS 19 Study Grp and Edaravone (MCI-186) ALS 19 Study Group and Writing Group
Lancet Neurology, The, ISSN 1474-4422, 2017, Volume 16, Issue 7, pp. 505 - 512
Summary Background In a previous phase 3 study in patients with amyotrophic lateral sclerosis (ALS), edaravone did not show a significant difference in the... 
Neurology | OXIDATIVE STRESS | DISEASE | FTD | FREE-RADICAL SCAVENGER | MCI-186 | HEXANUCLEOTIDE REPEAT | C9ORF72 | SPORADIC ALS | DAMAGE | CLINICAL NEUROLOGY | DECLINE | Free Radical Scavengers - pharmacology | Severity of Illness Index | Antipyrine - adverse effects | Double-Blind Method | Outcome Assessment (Health Care) | Antipyrine - pharmacology | Humans | Middle Aged | Amyotrophic Lateral Sclerosis - diagnosis | Free Radical Scavengers - administration & dosage | Male | Amyotrophic Lateral Sclerosis - drug therapy | Young Adult | Antipyrine - administration & dosage | Antipyrine - analogs & derivatives | Adult | Female | Aged | Free Radical Scavengers - adverse effects | Clinical trials | Amyotrophic lateral sclerosis | Analysis | Oxidative stress | Stroke | Free radicals | Intravenous administration | Disease | Exanthema | Data processing | Population studies | Brain research | Dyspnea | Rodents | Classification | Questionnaires | Biomarkers | Dysphagia | Respiration
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3. Full Text Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults
by Abarca-Gómez, Leandra and Abdeen, Ziad A and Hamid, Zargar Abdul and Abu-Rmeileh, Niveen M and Acosta-Cazares, Benjamin and Acuin, Cecilia and Adams, Robert J and Aekplakorn, Wichai and Afsana, Kaosar and Aguilar-Salinas, Carlos A and Agyemang, Charles and Ahmadvand, Alireza and Ahrens, Wolfgang and Ajlouni, Kamel and Akhtaeva, Nazgul and Al-Hazzaa, Hazzaa M and Al-Othman, Amani Rashed and Al-Raddadi, Rajaa and Al Buhairan, Fadia and Al Dhukair, Shahla and Ali, Osman and Ali, Mohamed M and Alkerwi, Ala'a and Alvarez-Pedrerol, Mar and Aly, Eman and Amarapurkar, Deepak N and Amouyel, Philippe and Amuzu, Antoinette and Andersen, Lars Bo and Anderssen, Sigmund A and Andrade, Dolores S and Ängquist, Lars H and Anjana, Ranjit Mohan and Aounallah-Skhiri, Hajer and Araújo, Joana and Ariansen, Inger and Aris, Tahir and Arlappa, Nimmathota and Arveiler, Dominique and Aryal, Krishna K and Aspelund, Thor and Assah, Felix K and Assunção, Maria Cecília F and Aung, May Soe and Avdicová, Mária and Azevedo, Ana and Azizi, Fereidoun and Babu, Bontha V and Bahijri, Suhad and Baker, Jennifer L and Balakrishna, Nagalla and Bamoshmoosh, Mohamed and Banach, Maciej and Bandosz, Piotr and Banegas, José R and Barbagallo, Carlo M and Barceló, Alberto and Barkat, Amina and Barros, Aluisio JD and Barros, Mauro VG and Bata, Iqbal and Batieha, Anwar M and Batista, Rosangela L and Batyrbek, Assembekov and Baur, Louise A and Beaglehole, Robert and Romdhane, Habiba Ben and Benedics, Judith and Benet, Mikhail and Bennett, James E and Bernabe-Ortiz, Antonio and Bernotiene, Gailute and Bettiol, Heloisa and Bhagyalaxmi, Aroor and Bharadwaj, Sumit and Bhargava, Santosh K and Bhatti, Zaid and Bhutta, Zulfiqar A and Bi, Hongsheng and Bi, Yufang and Biehl, Anna and Bikbov, Mukharram and Bista, Bihungum and Bjelica, Dusko J and Bjerregaard, Peter and Bjertness, Marius B and Bjertness, Espen and Björkelund, Cecilia and Blokstra, Anneke and Bo, Simona and Bobak, Martin and Boddy, Lynne M and Boehm, Bernhard O and Boeing, Heiner and Boggia, Jose G and Boissonnet, Carlos P and Bonaccio, Marialaura and Bongard, Vanina and Bovet, Pascal and Braeckevelt, Lien and ... and NCD Risk Factor Collaboration (NCD-RisC) and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Omvårdnad
The Lancet, ISSN 0140-6736, 12/2017, Volume 390, Issue 10113, pp. 2627 - 2642
Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to... 
Body Mass Index | Prevalence | Age Factors | Humans | Child, Preschool | Male | Young Adult | Thinness - epidemiology | Overweight - epidemiology | Obesity - epidemiology | Adolescent | Bayes Theorem | Global Health - statistics & numerical data | Sex Factors | Adult | Female | Child | Pediatric Obesity - epidemiology | Adolescence | Body mass index | Obesity | Infectious diseases | Body weight | Underweight | Population studies | Adults | Children | Adolescents | Weight | VDP | Medisinske Fag: 700 | Klinisk medisinske fag: 750 | Clinical medical disciplines: 750 | Medical disciplines: 700 | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
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4. Full Text Association of myopic deformation of optic disc with visual field progression in paired eyes with open-angle glaucoma
by Sawada, Yu and Hangai, Masanori and Ishikawa, Makoto and Yoshitomi, Takeshi
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, p. e0170733
Purpose The influence of myopia on glaucoma progression remains unknown, possibly because of the multifactorial nature of glaucoma and difficulty in assessing... 
PARAPAPILLARY ATROPHY | METAANALYSIS | NORMAL-TENSION GLAUCOMA | RISK-FACTOR | PERIPAPILLARY ATROPHY | MULTIDISCIPLINARY SCIENCES | BETA-ZONE | INTRAOCULAR-PRESSURE | NERVE HEAD BIOMECHANICS | MICROSTRUCTURE | DAMAGE | Optic Disk - physiopathology | Tomography, Optical Coherence | Visual Fields | Humans | Middle Aged | Glaucoma, Open-Angle - physiopathology | Adult | Female | Male | Aged | Disease Progression | Complications and side effects | Prognosis | Open-angle glaucoma | Myopia | Development and progression | Genetic aspects | Research | Glaucoma | Optic nerve | Deformation | Visual field | Optics | Systematic review | Regression analysis | Multivariate analysis | Risk factors | Defects | Eye | Atrophy | Medicine | Studies | Biomechanics | Surgery | Tomography | Eye (anatomy) | Visual fields | University graduates | Enlargement
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5. Full Text Association of myopic optic disc deformation with visual field defects in paired eyes with open-angle glaucoma: A cross-sectional study
by Sawada, Yu and Hangai, Masanori and Ishikawa, Makoto and Yoshitomi, Takeshi
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, p. e0161961
Purpose To examine the association of myopia with the visual field (VF) defects in open-angle glaucoma (OAG) using paired eyes to eliminate the effect of... 
POPULATION | MULTIDISCIPLINARY SCIENCES | INTRAOCULAR-PRESSURE | LOW-TENSION GLAUCOMA | SCLERA | COHERENCE TOMOGRAPHY | PROGRESSION | DAMAGE | Visual Fields - physiology | Cross-Sectional Studies | Humans | Middle Aged | Glaucoma, Open-Angle - physiopathology | Linear Models | Male | Myopia - physiopathology | Adult | Female | Aged | Visual Field Tests | Bruch Membrane - metabolism | Optic Disk - physiology | Complications and side effects | Prognosis | Open-angle glaucoma | Myopia | Development and progression | Research | Risk factors | Glaucoma | Deformation | Visual field | Optics | Systematic review | Regression analysis | Patients | Defects | Eye | Medicine | Studies | Atrophy | Tomography | Eye (anatomy) | Visual fields | University graduates
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6. Full Text The quiescent intracluster medium in the core of the Perseus cluster
by Aharonian, Felix and Akamatsu, Hiroki and Akimoto, Fumie and Allen, Steven W and Anabuki, Naohisa and Angelini, Lorella and Arnaud, Keith and Audard, Marc and Awaki, Hisamitsu and Axelsson, Magnus and Bamba, Aya and Bautz, Marshall and Blandford, Roger and Brenneman, Laura and Brown, Gregory V and Bulbul, Esra and Cackett, Edward and Chernyakova, Maria and Chiao, Meng and Coppi, Paolo and Costantini, Elisa and De Plaa, Jelle and Den Herder, Jan-Willem and Done, Chris and Dotani, Tadayasu and Ebisawa, Ken and Eckart, Megan and Enoto, Teruaki and Ezoe, Yuichiro and Fabian, Andrew C and Ferrigno, Carlo and Foster, Adam and Fujimoto, Ryuichi and Fukazawa, Yasushi and Furuzawa, Akihiro and Galeazzi, Massimiliano and Gallo, Luigi and Gandhi, Poshak and Giustini, Margherita and Goldwurm, Andrea and Gu, Liyi and Guainazzi, Matteo and Haba, Yoshito and Hagino, Kouichi and Hamaguchi, Kenji and Harrus, Ilana and Hatsukade, Isamu and Hayashi, Katsuhiro and Hayashi, Takayuki and Hayashida, Kiyoshi and Hiraga, Junko and Hornschemeier, Ann and Hoshino, Akio and Hughes, John and Iizuka, Ryo and Inoue, Hajime and Inoue, Yoshiyuki and Ishibashi, Kazunori and Ishida, Manabu and Ishikawa, Kumi and Ishisaki, Yoshitaka and Itoh, Masayuki and Iyomoto, Naoko and Kaastra, Jelle and Kallman, Timothy and Kamae, Tuneyoshi and Kara, Erin and Kataoka, Jun and Katsuda, Satoru and Katsuta, Junichiro and Kawaharada, Madoka and Kawai, Nobuyuki and Kelley, Richard and Khangulyan, Dmitry and Kilbourne, Caroline and King, Ashley and Kitaguchi, Takao and Kitamoto, Shunji and Kitayama, Tetsu and Kohmura, Takayoshi and Kokubun, Motohide and Koyama, Shu and Koyama, Katsuji and Kretschmar, Peter and Krimm, Hans and Kubota, Aya and Kunieda, Hideyo and Laurent, Philippe and Lebrun, François and Lee, Shiu-Hang and Leutenegger, Maurice and Limousin, Olivier and Loewenstein, Michael and Long, Knox S and Lumb, David and Madejski, Grzegorz and Maeda, Yoshitomo and Maier, Daniel and Makishima, Kazuo and Markevitch, Maxim and ... and Hitomi Collaboration and SLAC National Accelerator Lab., Menlo Park, CA (United States)
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 117 - 121
Clusters of galaxies are the most massive gravitationally bound objects in the Universe and are still forming. They are thus important probes(1) of... 
NGC 1275 | GALAXY CLUSTERS | TURBULENT VELOCITY | MULTIDISCIPLINARY SCIENCES | LINE | GAS | NGC-1275 | CONSTRAINTS | X-RAY SPECTROSCOPY | XMM-NEWTON | FEEDBACK | Clusters | Observations | Stars | Cosmology | Astrophysics | Velocity | Stars & galaxies | ASTRONOMY AND ASTROPHYSICS | GRQC | ASTRO
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