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1. Full Text Morcellation worsens survival outcomes in patients with undiagnosed uterine leiomyosarcomas: A retrospective MITO group study
by Raspagliesi, Francesco, M.D and Maltese, Giuseppa, M.D and Bogani, Giorgio, M.D., Ph.D and Fucà, Giovanni, M.D and Lepori, Stefano, M.D and De Iaco, Pierandrea, M.D and Perrone, Myriam, M.D and Scambia, Giovanni, M.D and Cormio, Gennaro, M.D and Bogliolo, Stefano, M.D and Bergamini, Alice, M.D and Bifulco, Giuseppe, M.D and Casali, Paolo Giovanni, M.D and Lorusso, Domenica, M.D., Ph.D
Gynecologic Oncology, ISSN 0090-8258, 2016, Volume 144, Issue 1, pp. 90 - 95
Abstract Objective To investigate the impact of morcellation on survival outcomes of patients affected by undiagnosed uterine sarcoma. Methods This is a... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | Morcellation | Myoma | Laparoscopy | Sarcoma | Survival | SURGERY | SERIES | UTERUS | LEIOMYOMAS | CANCER | OBSTETRICS & GYNECOLOGY | IMPACT | ONCOLOGY | SARCOMAS | TUMOR MORCELLATION | LAPAROSCOPIC HYSTERECTOMY | GRAY-SCALE | Smooth Muscle Tumor - diagnosis | Leiomyosarcoma - pathology | Uterine Neoplasms - pathology | Humans | Middle Aged | Leiomyoma - diagnosis | Smooth Muscle Tumor - pathology | Morcellation - adverse effects | Leiomyoma - pathology | Disease-Free Survival | Laparoscopy - methods | Uterine Neoplasms - surgery | Leiomyoma - surgery | Leiomyosarcoma - surgery | Adult | Female | Retrospective Studies | Smooth Muscle Tumor - surgery | Leiomyosarcoma - diagnosis | Uterine Neoplasms - diagnosis | Morcellation - methods | Medicine, Experimental | Medical research
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2. Full Text beta-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer
by Tocci, P and Cianfrocca, R and Di Castro, V and Rosano, L and Sacconi, A and Donzelli, S and Bonfiglio, S and Bucci, G and Vizza, E and Ferrandina, G and Scambia, G and Tonon, G and Blandino, G and Bagnato, A
NATURE COMMUNICATIONS, ISSN 2041-1723, 07/2019, Volume 10, Issue 1, pp. 3196 - 15
The limited clinical response observed in high-grade serous ovarian cancer (HG-SOC) with high frequency of TP53 mutations (mutp53) might be related to... 
BREAST-CANCER | KAPPA-B ACTIVATION | BETA-ARRESTIN-1 | BETA-ARRESTINS | MULTIDISCIPLINARY SCIENCES | GROWTH | NUCLEAR EXPORT SIGNAL | HIPPO PATHWAY | YAP | MACITENTAN | G-PROTEIN | Ovarian carcinoma | p53 Protein | Xenotransplantation | RhoA protein | Tethering | Antagonists | Endothelin 1 | Patients | Ovarian cancer | Anticancer properties | Yes-associated protein | Receptors | Transcription activation | Cell lines | Xenografts | Mutation | Combinatorial analysis | Cancer
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3. Full Text Clinical Performance of Human Papillomavirus E6 and E7 mRNA Testing for High-Grade Lesions of the Cervix
by Paola Cattani and Gian Franco Zannoni and Caterina Ricci and Sara D'Onghia and Ilaria Nausica Trivellizzi and Aldo Di Franco and Valerio G. Vellone and Maria Durante and Giovanni Fadda and Giovanni Scambia and Giovanni Capelli and Rosa De Vincenzo
Journal of Clinical Microbiology, ISSN 0095-1137, 12/2009, Volume 47, Issue 12, pp. 3895 - 3901
Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
VIRAL LOAD | SQUAMOUS INTRAEPITHELIAL LESIONS | POLYMERASE-CHAIN-REACTION | CANCER WORLDWIDE | PRETECT(TM) HPV-PROOFER | MICROBIOLOGY | 2-YEAR FOLLOW-UP | NATURAL-HISTORY | YOUNG-WOMEN | RISK HUMAN-PAPILLOMAVIRUS | ONCOGENE TRANSCRIPTS | Predictive Value of Tests | Carcinoma, Squamous Cell - virology | Humans | Middle Aged | RNA, Messenger - analysis | DNA, Viral - analysis | Papillomavirus Infections - diagnosis | Papillomavirus E7 Proteins - genetics | Polymerase Chain Reaction - methods | Carcinoma, Squamous Cell - diagnosis | Young Adult | RNA, Viral - genetics | Sensitivity and Specificity | Adult | Female | Oncogene Proteins, Viral - genetics | Papillomavirus Infections - virology | Oncogene Proteins, Viral - metabolism | Uterine Cervical Neoplasms - diagnosis | RNA, Messenger - genetics | Cervical Intraepithelial Neoplasia - diagnosis | RNA, Viral - analysis | Cervix Uteri | Cervical Intraepithelial Neoplasia - virology | Papillomavirus E7 Proteins - metabolism | Uterine Cervical Neoplasms - virology | Aged | DNA, Viral - genetics | Virology
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4. Full Text The effect of a uterine manipulator on the recurrence and mortality of endometrial cancer: a multi-centric study by the Italian Society of Gynecological Endoscopy
by Uccella, Stefano, MD, PhD and Bonzini, Matteo, MD and Malzoni, Mario, MD and Fanfani, Francesco, MD and Palomba, Stefano, MD and Aletti, Giovanni, MD and Corrado, Giacomo, MD and Ceccaroni, Marcello, MD and Seracchioli, Renato, MD and Shakir, Fevzi, MD and Ferrero, Annamaria, MD and Berretta, Roberto, MD and Tinelli, Raffaele, MD and Vizza, Enrico, MD and Roviglione, Giovanni, MD and Casarella, Lucia, MD and Volpi, Eugenio, MD and Cicinelli, Ettore, MD and Scambia, Giovanni, MD and Ghezzi, Fabio, MD
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2017, Volume 216, Issue 6, pp. 592.e1 - 592.e11
Background Although widely adopted, the use of a uterine manipulator during laparoscopic treatment of endometrial cancer represents a debated issue, and some... 
Obstetrics and Gynecology | laparoscopy | recurrence | endometrial cancer | uterine manipulator | oncological safety | prognosis | SURGERY | SURVIVAL | MULTICENTER | MANAGEMENT | TOTAL LAPAROSCOPIC HYSTERECTOMY | OBSTETRICS & GYNECOLOGY | SPECIMENS | POSITIVE PERITONEAL CYTOLOGY | ONCOLOGY | ASSISTED VAGINAL HYSTERECTOMY | CARCINOMA | Myometrium - pathology | Endometrial Neoplasms - mortality | Humans | Middle Aged | Risk Factors | Survival Rate | Lymphatic Metastasis | Neoplasm Recurrence, Local - mortality | Neoplasm Recurrence, Local - surgery | Gynecologic Surgical Procedures - methods | Societies, Medical | Neoplasm Invasiveness - pathology | Gynecologic Surgical Procedures - instrumentation | Endometrial Neoplasms - pathology | Female | Italy | Aged | Neoplasm Recurrence, Local - epidemiology | Laparoscopy - instrumentation | Neoplasm Staging | Relapse | Endometrial cancer | Oncology, Experimental | Mortality | Endoscopy | Research | Health aspects | Trade and professional associations | Cancer | Diseases | Analysis
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5. Full Text A whole germline BRCA2 gene deletion: How to learn from CNV in silico analysis
by Scaglione, Giovanni Luca and Concolino, Paola and De Bonis, Maria and De Paolis, Elisa and Minucci, Angelo and Ferrandina, Gabriella and Scambia, Giovanni and Capoluongo, Ettore
International Journal of Molecular Sciences, ISSN 1661-6596, 04/2018, Volume 19, Issue 4, p. 961
BRCA1/2 screening in Hereditary Breast and Ovarian Syndrome (HBOC) is an essential step for effective patients' management. Next-Generation Sequencing (NGS)... 
BRCA1/2 | Data analysis | CNV | NGS | MLPA | HBOC | data analysis | OVARIAN-CANCER PATIENTS | QUANTIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, MULTIDISCIPLINARY | BREAST | TOOLS
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6. Full Text Adjuvant anastrozole versus exemestane versus letrozole, upfront or after 2 years of tamoxifen, in endocrine-sensitive breast cancer (FATA-GIM3): a randomised, phase 3 trial
by De Placido, Sabino and Gallo, Ciro and De Laurentiis, Michelino and Bisagni, Giancarlo and Arpino, Grazia and Sarobba, Maria Giuseppa and Riccardi, Ferdinando and Russo, Antonio and Del Mastro, Lucia and Cogoni, Alessio Aligi and Cognetti, Francesco and Gori, Stefania and Foglietta, Jennifer and Frassoldati, Antonio and Amoroso, Domenico and Laudadio, Lucio and Moscetti, Luca and Montemurro, Filippo and Verusio, Claudio and Bernardo, Antonio and Lorusso, Vito and Gravina, Adriano and Moretti, Anna and Moretti, Gabriella and Lauria, Rossella and Lai, Antonella and Mocerino, Carmela and Rizzo, Sergio and Nuzzo, Antonio and Nuzzo, Francesco and Carlini, Paolo and Perrone, Francesco and Accurso, Antonello and Agostara, Biagio and Aieta, Michele and Alabiso, Oscar and Alicicco, Maria Grazia and Amadori, Dino and Amaducci, Laura and Amiconi, Gianna and Antuzzi, Giustino and Ardine, Mara and Ardizzoia, Antonio and Aversa, Caterina and Badalamenti, Giuseppe and Barni, Sandro and Basurto, Carlo and Berardi, Rossana and Bergamasco, Cinzia and Bidoli, Paolo and Bighin, Claudia and Biondi, Edoardo and Boni, Corrado and Borgonovo, Karen and Botta, Mario and Bravi, Stefano and Bruzzi, Paolo and Buono, Giuseppe and Butera, Alfredo and Caldara, Alessia and Candeloro, Giampiero and Cappelletti, Claudia and Cardalesi, Cinzia and Carfora, Elisabetta and Cariello, Anna and Carrozza, Francesco and Cartenì, Giacomo and Caruso, Michele and Casadei, Virginia and Casanova, Claudia and Castori, Luigi and Cavanna, Luigi and Cavazzini, Giovanna and Cazzaniga, Marina and Chilelli, Mario and Chiodini, Paolo and Chiorrini, Silvia and Ciardiello, Fortunato and Ciccarese, Mariangela and Cinieri, Saverio and Clerico, Mario and Coccaro, Mariarosa and Comande, Mario and Corbo, Claudia and Cortino, Giuseppina and Cusenza, Stefania and Daniele, Gennaro and D'arco, Alfonso Maria and D'auria, Giuliana and Dazzi, Claudio and De Angelis, Carmine and de Braud, Filippo and De Feo, Gianfranco and De Matteis, Andrea and De Tursi, Michele and Di Blasio, Anna and di Lucca, Giuseppe and Di Lullo, Liberato and Di Rella, Francesca and Di Renzo, Gianfranco and ... and GIM Investigators
The Lancet Oncology, ISSN 1470-2045, 04/2018, Volume 19, Issue 4, pp. 474 - 485
Uncertainty exists about the optimal schedule of adjuvant treatment of breast cancer with aromatase inhibitors and, to our knowledge, no trial has directly... 
SYSTEM | THERAPY | EFFICACY | ONCOLOGY | FOLLOW-UP | POSTMENOPAUSAL WOMEN | COMBINATION | AROMATASE INHIBITORS | Breast cancer | Product development | Tamoxifen | Analysis
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7. Full Text Long-term efficacy and safety of human papillomavirus vaccination
by De Vincenzo, Rosa and Conte, Carmine and Ricci, Caterina and Scambia, Giovanni and Capelli, Giovanni
International Journal of Women's Health, ISSN 1179-1411, 12/2014, Volume 6, pp. 999 - 1010
In this paper, we review the published evidence about the long-term efficacy of the available human papillomavirus (HPV) vaccines and their safety profile. Two... 
Adverse events | Effectiveness | HPV vaccines | Prevention | Care and treatment | Research | Teenage girls | Health aspects | Papillomavirus infections | Risk factors | Studies | Human papillomavirus | Womens health | Aluminum | Human immunodeficiency virus--HIV | Infections | Vaccines | Deoxyribonucleic acid--DNA | Cervical cancer | Regulatory approval
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8. Full Text Laterally Extended Pelvic Resection for Gynaecological Malignancies: A Multicentric Experience with Out-of-the-Box Surgery
by Vizzielli, Giuseppe and Naik, Raj and Dostalek, Lukas and Bizzarri, Nicolò and Kucukmetin, Ali and Tinelli, Giovanni and Scambia, Giovanni and Cibula, David
Annals of Surgical Oncology, ISSN 1068-9265, 02/2019, Volume 26, Issue 2, pp. 523 - 530
To evaluate morbidity and oncological outcome in a multicentre series of women with gynaecological malignancies infiltrating pelvic side wall (PSW) that... 
SURGERY | ONCOLOGY | RECURRENT | EXCISION | EXENTERATION | CANCER | CARCINOMA | UTERINE
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9. Full Text A Randomized Trial of Lymphadenectomy in Patients with Advanced Ovarian Neoplasms
by Harter, Philipp and Sehouli, Jalid and Lorusso, Domenica and Reuss, Alexander and Vergote, Ignace and Marth, Christian and Kim, Jae-Weon and Raspagliesi, Francesco and Lampe, Björn and Aletti, Giovanni and Meier, Werner and Cibula, David and Mustea, Alexander and Mahner, Sven and Runnebaum, Ingo B and Schmalfeldt, Barbara and Burges, Alexander and Kimmig, Rainer and Scambia, Giovanni and Greggi, Stefano and Hilpert, Felix and Hasenburg, Annette and Hillemanns, Peter and Giorda, Giorgio and von Leffern, Ingo and Schade-Brittinger, Carmen and Wagner, Uwe and du Bois, Andreas
The New England Journal of Medicine, ISSN 0028-4793, 02/2019, Volume 380, Issue 9, pp. 822 - 832
A randomized trial evaluated whether resection of lymph nodes that appeared macroscopically normal during surgery for ovarian cancer would lead to improved... 
SURVIVAL | MEDICINE, GENERAL & INTERNAL | COMBINED EXPLORATORY ANALYSIS | IMPACT | MANAGEMENT | PATTERN | BEVACIZUMAB | RESECTION | PARAAORTIC LYMPHADENECTOMY | CANCER | PROGRAM | Lymph Node Excision - adverse effects | CA-125 Antigen - blood | Humans | Middle Aged | Kaplan-Meier Estimate | Ovarian Neoplasms - pathology | Proportional Hazards Models | Survival Rate | Lymphatic Metastasis | Operative Time | Young Adult | Progression-Free Survival | Treatment Failure | Aged, 80 and over | Adult | Female | Aged | Postoperative Complications | Ovarian Neoplasms - surgery | Cancer patients | Care and treatment | Usage | Complications | Surgery | Development and progression | Health aspects | Lymph nodes | Risk factors | Ovarian cancer | Surgical outcomes | Fees & charges | Lymphatic system | Statistical analysis | Gynecology | Clinical trials | Oncology | Metastasis | Cancer therapies | Survival | Patients | Obstetrics | Quality of life | Chemotherapy | Medical prognosis | Full text | Boards of directors | Tumors
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10. Full Text The PTEN Tumor Suppressor Gene in Soft Tissue Sarcoma
by Stefano, S and Giovanni, S
CANCERS, ISSN 2072-6694, 08/2019, Volume 11, Issue 8, p. 1169
Soft tissue sarcoma (STS) is a rare malignancy of mesenchymal origin classified into more than 50 different subtypes with distinct clinical and pathologic... 
MAMMALIAN TARGET | synovial sarcoma | PHOSPHATIDYLINOSITOL 3-KINASE/AKT | malignant peripheral nerve sheath tumor | myxofibrosarcoma | PTEN | Soft tissue sarcoma | ADIPOCYTIC DIFFERENTIATION | leiomyosarcoma | undifferentiated pleomorphic sarcoma | MOLECULAR CLASSIFICATION | gastrointestinal stromal tumor | ONCOLOGY | epithelioid sarcoma | ESTROGEN-RECEPTOR-ALPHA | EPIDERMAL-GROWTH-FACTOR | liposarcoma | UTERINE LEIOMYOSARCOMAS | NERVE SHEATH TUMORS
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11. Full Text Nadroparin for the prevention of thromboembolic events in ambulatory patients with metastatic or locally advanced solid cancer receiving chemotherapy: a randomised, placebo-controlled, double-blind study
by Agnelli, Giancarlo, Prof and Gussoni, Gualberto, MD and Bianchini, Carlo, MD and Verso, Melina, MD and Mandalà, Mario, MD and Cavanna, Luigi, MD and Barni, Sandro, MD and Labianca, Roberto, MD and Buzzi, Franco, MD and Scambia, Giovanni, Prof and Passalacqua, Rodolfo, MD and Ricci, Sergio, MD and Gasparini, Giampietro, MD and Lorusso, Vito and Bonizzoni, Erminio, PhD and Tonato, Maurizio, MD and PROTECHT Investigators
Lancet Oncology, The, ISSN 1470-2045, 2009, Volume 10, Issue 10, pp. 943 - 949
Summary Background Clinical trials are needed to assess the clinical benefit of antithrombotic prophylaxis in patients with cancer who are receiving... 
Hematology, Oncology and Palliative Medicine | SURVIVAL | RISK-FACTORS | METAANALYSIS | THERAPY | VENOUS THROMBOEMBOLISM | CLINICAL-TRIAL | ONCOLOGY | THROMBOSIS | BEVACIZUMAB | MOLECULAR-WEIGHT HEPARIN | ADVANCED MALIGNANCY | Double-Blind Method | Factor Xa Inhibitors | Humans | Middle Aged | Male | Thromboembolism - etiology | Antineoplastic Agents - administration & dosage | Nadroparin - administration & dosage | Neoplasms - complications | Neoplasms - therapy | Thromboembolism - prevention & control | Injections, Subcutaneous | Female | Aged | Fibrinolytic Agents - administration & dosage | Neoplasms - pathology | Thromboembolism - pathology | Cohort Studies | Prevention | Chemotherapy | Glycosaminoglycans | Oncology, Experimental | Clinical trials | Anticoagulants (Medicine) | Metastasis | Research | Thromboembolism | Cancer
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12. Full Text Neoadjuvant chemotherapy versus upfront debulking surgery in advanced tubo-ovarian cancer
by Fagotti, Anna and Scambia, Giovanni
The Lancet Oncology, ISSN 1470-2045, 12/2018, Volume 19, Issue 12, pp. 1558 - 1560
ONCOLOGY | OVARIAN-CANCER
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13. Full Text Standard first-line chemotherapy with or without nintedanib for advanced ovarian cancer (AGO-OVAR 12): a randomised, double-blind, placebo-controlled phase 3 trial
by du Bois, Andreas, Prof and Kristensen, Gunnar, Prof and Ray-Coquard, Isabelle, Prof and Reuss, Alexander, MSc and Pignata, Sandro, MD and Colombo, Nicoletta, Prof and Denison, Ursula, MD and Vergote, Ignace, Prof and del Campo, Jose M, MD and Ottevanger, Petronella, PhD and Heubner, Martin, MD and Minarik, Thomas, PhD and Sevin, Emmanuel, MD and de Gregorio, Nikolaus, MD and Bidziński, Mariusz, Prof and Pfisterer, Jacobus, Prof and Malander, Susanne, MD and Hilpert, Felix, Prof and Mirza, Mansoor R, MD and Scambia, Giovanni, Prof and Meier, Werner, Prof and Nicoletto, Maria O, MD and Bjørge, Line, Prof and Lortholary, Alain, MD and Sailer, Martin Oliver, PhD and Merger, Michael, MD and Harter, Philipp, MD and European Network Gynaecologic Onco and AGO Study Grp Led Gynecologic Canc and AGO Study Group led Gynecologic Cancer Intergroup/European Network of Gynaecologic Oncology Trials Groups Intergroup Consortium and Oncology and Pathology, Kamprad Lab and Lund University and Lunds universitet and Onkologi och Patologi, Kampradlab
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 1, pp. 78 - 89
Summary Background Angiogenesis is a target in the treatment of ovarian cancer. Nintedanib, an oral triple angiokinase inhibitor of VEGF receptor,... 
Hematology, Oncology and Palliative Medicine | BIBF 1120 | DES CANCERS | INTERGROUP TRIAL | LABEL DOSE-ESCALATION | CISPLATIN | ONCOLOGY | BEVACIZUMAB | TRIPLE ANGIOKINASE INHIBITOR | CARBOPLATIN PLUS PACLITAXEL | III TRIAL | MAINTENANCE THERAPY | Humans | Middle Aged | Ovarian Neoplasms - pathology | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Response Evaluation Criteria in Solid Tumors | Diarrhea - chemically induced | Cytoreduction Surgical Procedures | Indoles - administration & dosage | Young Adult | Peritoneal Neoplasms - drug therapy | Aged, 80 and over | Adult | Female | Carcinoma - pathology | Neutropenia - chemically induced | Paclitaxel - administration & dosage | Ovarian Neoplasms - drug therapy | Fallopian Tube Neoplasms - drug therapy | Carcinoma - drug therapy | Peritoneal Neoplasms - pathology | Double-Blind Method | Carcinoma - surgery | Peritoneal Neoplasms - surgery | Anemia - chemically induced | Carboplatin - administration & dosage | Fallopian Tube Neoplasms - pathology | Thrombocytopenia - chemically induced | Disease Progression | Disease-Free Survival | Indoles - adverse effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Fallopian Tube Neoplasms - surgery | Intention to Treat Analysis | Aged | Neoplasm Staging | Ovarian Neoplasms - surgery | Clinical trials | Chemotherapy | Hospitals | Growth factors | Cancer | Ovarian cancer | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
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