2010, Handbook of experimental pharmacology, ISBN 3642004776, Volume 197., xiv, 500
This overview on modern approaches to drug targeting covers today's options for specific carrier systems allowing successful drug treatment at problematic...
Drug Delivery Systems | Drug delivery systems | Pharmaceutical Sciences/Technology | Neurology | Oncology | Biomedicine | Pharmacology/Toxicology | Dermatology
Drug Delivery Systems | Drug delivery systems | Pharmaceutical Sciences/Technology | Neurology | Oncology | Biomedicine | Pharmacology/Toxicology | Dermatology
Book
1999, ISBN 0849327911, xv, 382
Book
Toxicology in Vitro, ISSN 0887-2333, 02/2015, Volume 29, Issue 1, pp. 113 - 123
Skin absorption testing in vitro is a regulatory accepted alternative method (OECD Guideline 428). Different tests can be applied to evaluate the integrity of...
TEWL | TEER | Integrity tests | Internal reference standard | Skin barrier function | Dermal absorption | VEHICLE | PERMEABILITY | RECONSTRUCTED HUMAN EPIDERMIS | BARRIER FUNCTION | TRANSEPIDERMAL WATER-LOSS | PENETRATION | ELECTRICAL-RESISTANCE | TOXICOLOGY | PERCUTANEOUS-ABSORPTION | SUNSCREEN FORMULATIONS | PERMEATION | Galvanic Skin Response - drug effects | Animals | Methylene Blue - pharmacokinetics | Skin - metabolism | Water Loss, Insensible - drug effects | Humans | Rats | Skin Absorption - drug effects | Female | In Vitro Techniques | Skin - drug effects | Medical tests | Skin | Index Medicus
TEWL | TEER | Integrity tests | Internal reference standard | Skin barrier function | Dermal absorption | VEHICLE | PERMEABILITY | RECONSTRUCTED HUMAN EPIDERMIS | BARRIER FUNCTION | TRANSEPIDERMAL WATER-LOSS | PENETRATION | ELECTRICAL-RESISTANCE | TOXICOLOGY | PERCUTANEOUS-ABSORPTION | SUNSCREEN FORMULATIONS | PERMEATION | Galvanic Skin Response - drug effects | Animals | Methylene Blue - pharmacokinetics | Skin - metabolism | Water Loss, Insensible - drug effects | Humans | Rats | Skin Absorption - drug effects | Female | In Vitro Techniques | Skin - drug effects | Medical tests | Skin | Index Medicus
Journal Article
Advanced Drug Delivery Reviews, ISSN 0169-409X, 2007, Volume 59, Issue 6, pp. 427 - 443
Due to the lower risk of systemic side effects topical treatment of skin disease appears favourable, yet the stratum corneum counteracts the penetration of...
Nanostructured lipid carriers | Topical glucocorticoids | Skin | Active pharmaceutical ingredient (API) | Benefit/risk ratio | Drug-carrier interactions | Solid lipid nanoparticles | Topical use | API-carrier interactions | VITRO PERCUTANEOUS-ABSORPTION | HUMAN STRATUM-CORNEUM | RECONSTRUCTED HUMAN EPIDERMIS | solid lipid nanoparticles | TRANSDERMAL DELIVERY | skin | topical glucocorticoids | PARELECTRIC SPECTROSCOPY | drug-carrier interactions | IN-VITRO | PHYSICOCHEMICAL CHARACTERIZATION | RISK-BENEFIT RATIO | topical use | active pharmaceutical ingredient (API) | benefit/risk ratio | TRIAMCINOLONE-ACETONIDE | PHARMACOLOGY & PHARMACY | BENZOYL PEROXIDE | nanostructured lipid carriers | Drug Carriers - therapeutic use | Skin Diseases - metabolism | Humans | Drug Carriers - administration & dosage | Skin Absorption | Skin Diseases - drug therapy | Lipids - administration & dosage | Lipids - therapeutic use | Pharmaceutical Preparations - metabolism | Animals | Nanoparticles - therapeutic use | Nanoparticles - administration & dosage | Pharmaceutical Preparations - administration & dosage | Administration, Topical | Drugs | Nanoparticles | Drug delivery systems | Corticosteroids | Dermatology | Formulae, receipts, prescriptions | Skin diseases | Dermatologic agents | Lipids | Xenobiotics | Nanotechnology | Vehicles
Nanostructured lipid carriers | Topical glucocorticoids | Skin | Active pharmaceutical ingredient (API) | Benefit/risk ratio | Drug-carrier interactions | Solid lipid nanoparticles | Topical use | API-carrier interactions | VITRO PERCUTANEOUS-ABSORPTION | HUMAN STRATUM-CORNEUM | RECONSTRUCTED HUMAN EPIDERMIS | solid lipid nanoparticles | TRANSDERMAL DELIVERY | skin | topical glucocorticoids | PARELECTRIC SPECTROSCOPY | drug-carrier interactions | IN-VITRO | PHYSICOCHEMICAL CHARACTERIZATION | RISK-BENEFIT RATIO | topical use | active pharmaceutical ingredient (API) | benefit/risk ratio | TRIAMCINOLONE-ACETONIDE | PHARMACOLOGY & PHARMACY | BENZOYL PEROXIDE | nanostructured lipid carriers | Drug Carriers - therapeutic use | Skin Diseases - metabolism | Humans | Drug Carriers - administration & dosage | Skin Absorption | Skin Diseases - drug therapy | Lipids - administration & dosage | Lipids - therapeutic use | Pharmaceutical Preparations - metabolism | Animals | Nanoparticles - therapeutic use | Nanoparticles - administration & dosage | Pharmaceutical Preparations - administration & dosage | Administration, Topical | Drugs | Nanoparticles | Drug delivery systems | Corticosteroids | Dermatology | Formulae, receipts, prescriptions | Skin diseases | Dermatologic agents | Lipids | Xenobiotics | Nanotechnology | Vehicles
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 2010, Volume 87, Issue 2, pp. 274 - 281
Generalized peeling skin disease is an autosomal-recessive ichthyosiform erythroderma characterized by lifelong patchy peeling of the skin. After genome-wide...
ICHTHYOSIS VULGARIS | GENE | RECONSTRUCTED HUMAN EPIDERMIS | HYPOTRICHOSIS SIMPLEX | FILAGGRIN | DESQUAMATION | GENETICS & HEREDITY | STRATUM-CORNEUM | OF-FUNCTION MUTATIONS | PERCUTANEOUS-ABSORPTION | NETHERTON-SYNDROME | Glycoproteins - genetics | Epidermis - pathology | Humans | Molecular Sequence Data | Male | Chromosome Mapping | Pruritus - genetics | DNA Mutational Analysis | Models, Biological | Pedigree | Base Sequence | Skin - ultrastructure | Family | Glycoproteins - deficiency | Pruritus - complications | Child | Skin - pathology | Gene mutations | Human genome | Analysis | Skin diseases | Genetic aspects | Research | Cell adhesion molecules | Report
ICHTHYOSIS VULGARIS | GENE | RECONSTRUCTED HUMAN EPIDERMIS | HYPOTRICHOSIS SIMPLEX | FILAGGRIN | DESQUAMATION | GENETICS & HEREDITY | STRATUM-CORNEUM | OF-FUNCTION MUTATIONS | PERCUTANEOUS-ABSORPTION | NETHERTON-SYNDROME | Glycoproteins - genetics | Epidermis - pathology | Humans | Molecular Sequence Data | Male | Chromosome Mapping | Pruritus - genetics | DNA Mutational Analysis | Models, Biological | Pedigree | Base Sequence | Skin - ultrastructure | Family | Glycoproteins - deficiency | Pruritus - complications | Child | Skin - pathology | Gene mutations | Human genome | Analysis | Skin diseases | Genetic aspects | Research | Cell adhesion molecules | Report
Journal Article
International Journal of Antimicrobial Agents, ISSN 0924-8579, 2009, Volume 35, Issue 4, pp. 366 - 374
Abstract Quinolones and glucocorticoids are frequently used drugs that may cause tendinopathy as a rare adverse effect. We exposed human tenocyte cultures to...
Infectious Disease | Levofloxacin | Dexamethasone | Tenocytes | Glucocorticoids | Ciprofloxacin | Quinolones | MATRIX | APOPTOSIS | INFECTIOUS DISEASES | ACHILLES-TENDON | HUMAN TENOCYTES | MICROBIOLOGY | FLUOROQUINOLONES | GENE-EXPRESSION | RUPTURE | PHARMACOLOGY & PHARMACY | TENDINOPATHY | ANTIINFLAMMATORY DRUGS | Cell Line | Up-Regulation | Quinolones - toxicity | Tendons - drug effects | Anti-Inflammatory Agents - toxicity | Down-Regulation | Humans | Dexamethasone - toxicity | Matrix Metalloproteinase 1 - biosynthesis | Integrin beta1 - biosynthesis | Matrix Metalloproteinase 13 - biosynthesis | Collagen Type I - biosynthesis | Anti-Inflammatory Agents - adverse effects | Anti-Bacterial Agents - adverse effects | Anti-Bacterial Agents - toxicity | Apoptosis | Collagen | Central nervous system depressants | Index Medicus
Infectious Disease | Levofloxacin | Dexamethasone | Tenocytes | Glucocorticoids | Ciprofloxacin | Quinolones | MATRIX | APOPTOSIS | INFECTIOUS DISEASES | ACHILLES-TENDON | HUMAN TENOCYTES | MICROBIOLOGY | FLUOROQUINOLONES | GENE-EXPRESSION | RUPTURE | PHARMACOLOGY & PHARMACY | TENDINOPATHY | ANTIINFLAMMATORY DRUGS | Cell Line | Up-Regulation | Quinolones - toxicity | Tendons - drug effects | Anti-Inflammatory Agents - toxicity | Down-Regulation | Humans | Dexamethasone - toxicity | Matrix Metalloproteinase 1 - biosynthesis | Integrin beta1 - biosynthesis | Matrix Metalloproteinase 13 - biosynthesis | Collagen Type I - biosynthesis | Anti-Inflammatory Agents - adverse effects | Anti-Bacterial Agents - adverse effects | Anti-Bacterial Agents - toxicity | Apoptosis | Collagen | Central nervous system depressants | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e42616
Oral mucositis is one of the most common side effects of chemoradiation regimens and manifestation can be dose-limiting for the therapy, can impair the...
SIGNAL-TRANSDUCTION | TGF-BETA | PAIN | MULTIDISCIPLINARY SCIENCES | KERATINOCYTES | MAP KINASES | PROLIFERATION | GROWTH-FACTOR | SKIN | MU-OPIATE RECEPTOR | ANALGESIA | Receptors, Opioid, delta - metabolism | Cell Line | Cell Survival - drug effects | Mouth Mucosa - cytology | Receptors, Opioid - agonists | Receptors, Opioid - genetics | Gene Expression | Epithelial Cells - metabolism | Morphine - pharmacology | Epithelial Cells - drug effects | Humans | Cell Movement - drug effects | Signal Transduction - drug effects | Receptors, Opioid, delta - genetics | Cell Proliferation - drug effects | Wound Healing - genetics | Receptors, Opioid, delta - agonists | Wound Healing - drug effects | Mitogen-Activated Protein Kinases - metabolism | Receptors, Opioid - metabolism | Morphine | Skin | Research | Transforming growth factors | Health aspects | Laboratories | Epithelial cells | Nervous system | Neuroblastoma | Kinases | Cancer therapies | Cell adhesion & migration | Angiogenesis | Signal transduction | Receptors | Pain | Epidermal growth factor | Penicillin | Fibroblasts | Medical research | Wound healing | Mucositis | Narcotics | Incubation | Mortality | Melanoma | Extracellular signal-regulated kinase | MAP kinase | Inflammation | Radiation therapy | Complex systems | Opioid receptors (type delta) | Quality of life | Side effects | Pharmacy | Stem cells | In vivo methods and tests | Diabetes | Receptor mechanisms | Cell migration | Tumors
SIGNAL-TRANSDUCTION | TGF-BETA | PAIN | MULTIDISCIPLINARY SCIENCES | KERATINOCYTES | MAP KINASES | PROLIFERATION | GROWTH-FACTOR | SKIN | MU-OPIATE RECEPTOR | ANALGESIA | Receptors, Opioid, delta - metabolism | Cell Line | Cell Survival - drug effects | Mouth Mucosa - cytology | Receptors, Opioid - agonists | Receptors, Opioid - genetics | Gene Expression | Epithelial Cells - metabolism | Morphine - pharmacology | Epithelial Cells - drug effects | Humans | Cell Movement - drug effects | Signal Transduction - drug effects | Receptors, Opioid, delta - genetics | Cell Proliferation - drug effects | Wound Healing - genetics | Receptors, Opioid, delta - agonists | Wound Healing - drug effects | Mitogen-Activated Protein Kinases - metabolism | Receptors, Opioid - metabolism | Morphine | Skin | Research | Transforming growth factors | Health aspects | Laboratories | Epithelial cells | Nervous system | Neuroblastoma | Kinases | Cancer therapies | Cell adhesion & migration | Angiogenesis | Signal transduction | Receptors | Pain | Epidermal growth factor | Penicillin | Fibroblasts | Medical research | Wound healing | Mucositis | Narcotics | Incubation | Mortality | Melanoma | Extracellular signal-regulated kinase | MAP kinase | Inflammation | Radiation therapy | Complex systems | Opioid receptors (type delta) | Quality of life | Side effects | Pharmacy | Stem cells | In vivo methods and tests | Diabetes | Receptor mechanisms | Cell migration | Tumors
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 03/2016, Volume 136, Issue 3, pp. 631 - 639
Atopic dermatitis is a chronic skin condition with complex etiology. It is characterized by skin barrier defects and T helper type 2 (Th2)-polarized...
ATOPIC-DERMATITIS | KERATINOCYTE DIFFERENTIATION | ENHANCED EXPRESSION | RECONSTRUCTED HUMAN EPIDERMIS | INNATE IMMUNE-RESPONSE | BARRIER FUNCTION | STRATUM-CORNEUM | STAPHYLOCOCCUS-AUREUS | ANTIMICROBIAL PEPTIDES | THYMIC STROMAL LYMPHOPOIETIN | DERMATOLOGY
ATOPIC-DERMATITIS | KERATINOCYTE DIFFERENTIATION | ENHANCED EXPRESSION | RECONSTRUCTED HUMAN EPIDERMIS | INNATE IMMUNE-RESPONSE | BARRIER FUNCTION | STRATUM-CORNEUM | STAPHYLOCOCCUS-AUREUS | ANTIMICROBIAL PEPTIDES | THYMIC STROMAL LYMPHOPOIETIN | DERMATOLOGY
Journal Article
Experimental Dermatology, ISSN 0906-6705, 05/2014, Volume 23, Issue 5, pp. 326 - 331
Cationic antimicrobial peptides are ancient natural broad‐spectrum antibiotics, and several compounds also exhibit anticancer activity. However, most...
Candida albicans | cell‐penetrating peptides | skin penetration | antimicrobial peptides | squamous cell carcinoma | Skin penetration | Squamous cell carcinoma | Cell-penetrating peptides | Antimicrobial peptides | INTRACELLULAR PROTEIN DELIVERY | FUNGICIDAL ACTIVITY | RECONSTRUCTED HUMAN EPIDERMIS | COMBINATION | CANCER | DERMATOLOGY | IN-VITRO | cell-penetrating peptides | LEUKEMIA-CELLS | TRANSDERMAL DRUG-DELIVERY | MELITTIN | Antifungal Agents - pharmacology | Melitten - therapeutic use | Cell Survival - drug effects | Skin Neoplasms - drug therapy | Enzyme-Linked Immunosorbent Assay | Peptides - chemistry | Humans | Amphotericin B - pharmacology | Antimicrobial Cationic Peptides - pharmacology | Skin - enzymology | Antimicrobial Cationic Peptides - therapeutic use | Candida albicans - drug effects | Carcinoma, Squamous Cell - drug therapy | Keratinocytes - drug effects | Carrier Proteins - pharmacology | Cell Line, Tumor | Melitten - pharmacology | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Fluorouracil - pharmacology | Protamines - pharmacology | Skin - drug effects | Enzymes | Care and treatment | Bacterial infections | Peptides | Dermatology | Melanoma | Dermatologic agents | Skin cancer | Amphotericin B | Formulae, receipts, prescriptions | Antiparasitic agents | Skin | Cancer | Fluorouracil | Index Medicus
Candida albicans | cell‐penetrating peptides | skin penetration | antimicrobial peptides | squamous cell carcinoma | Skin penetration | Squamous cell carcinoma | Cell-penetrating peptides | Antimicrobial peptides | INTRACELLULAR PROTEIN DELIVERY | FUNGICIDAL ACTIVITY | RECONSTRUCTED HUMAN EPIDERMIS | COMBINATION | CANCER | DERMATOLOGY | IN-VITRO | cell-penetrating peptides | LEUKEMIA-CELLS | TRANSDERMAL DRUG-DELIVERY | MELITTIN | Antifungal Agents - pharmacology | Melitten - therapeutic use | Cell Survival - drug effects | Skin Neoplasms - drug therapy | Enzyme-Linked Immunosorbent Assay | Peptides - chemistry | Humans | Amphotericin B - pharmacology | Antimicrobial Cationic Peptides - pharmacology | Skin - enzymology | Antimicrobial Cationic Peptides - therapeutic use | Candida albicans - drug effects | Carcinoma, Squamous Cell - drug therapy | Keratinocytes - drug effects | Carrier Proteins - pharmacology | Cell Line, Tumor | Melitten - pharmacology | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | Fluorouracil - pharmacology | Protamines - pharmacology | Skin - drug effects | Enzymes | Care and treatment | Bacterial infections | Peptides | Dermatology | Melanoma | Dermatologic agents | Skin cancer | Amphotericin B | Formulae, receipts, prescriptions | Antiparasitic agents | Skin | Cancer | Fluorouracil | Index Medicus
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 8/2005, Volume 83, Issue 8, pp. 587 - 595
Antimicrobial peptides are small, cationic, amphiphilic peptides of 12–50 amino acids with microbicidal activity against both bacteria and fungi. The...
Life Sciences | Human neutrophil peptides | HBD-4 | Human defensins | HBD-3 | Antimicrobial peptides | MEDICINE, RESEARCH & EXPERIMENTAL | human defensins | ANTIBACTERIAL PEPTIDES | BETA-DEFENSIN | HUMAN AIRWAY EPITHELIA | NEUTROPHIL DEFENSINS | HUMAN INTESTINAL DEFENSIN | INNATE HOST DEFENSES | human neutrophil peptides | HUMAN BETA-DEFENSIN-1 | GENETICS & HEREDITY | STAPHYLOCOCCUS-AUREUS | CYSTIC-FIBROSIS | EPITHELIAL ANTIMICROBIAL PEPTIDES | antimicrobial peptides | Defensins - metabolism | Animals | Anti-Infective Agents - metabolism | Humans | Antimicrobial Cationic Peptides - pharmacology | Defensins - classification | Anti-Infective Agents - classification | Chemistry, Pharmaceutical | Research | Peptides | Structure | Analysis
Life Sciences | Human neutrophil peptides | HBD-4 | Human defensins | HBD-3 | Antimicrobial peptides | MEDICINE, RESEARCH & EXPERIMENTAL | human defensins | ANTIBACTERIAL PEPTIDES | BETA-DEFENSIN | HUMAN AIRWAY EPITHELIA | NEUTROPHIL DEFENSINS | HUMAN INTESTINAL DEFENSIN | INNATE HOST DEFENSES | human neutrophil peptides | HUMAN BETA-DEFENSIN-1 | GENETICS & HEREDITY | STAPHYLOCOCCUS-AUREUS | CYSTIC-FIBROSIS | EPITHELIAL ANTIMICROBIAL PEPTIDES | antimicrobial peptides | Defensins - metabolism | Animals | Anti-Infective Agents - metabolism | Humans | Antimicrobial Cationic Peptides - pharmacology | Defensins - classification | Anti-Infective Agents - classification | Chemistry, Pharmaceutical | Research | Peptides | Structure | Analysis
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 10/2017, Volume 1405, Issue 1, pp. 202 - 214
Targeted topical application promises high drug concentrations in the skin and low systemic adverse effects. To locate drugs and drug‐delivery systems like...
FLIM | reconstructed human skin | drug delivery system | tight junctions | biomacromolecules | time‐resolved fluorescence spectroscopy | Reconstructed human skin | Biomacromolecules | Tight junctions | Time-resolved fluorescence spectroscopy | Drug delivery system | LOCALIZATION | DRUG-DELIVERY | MULTIDISCIPLINARY SCIENCES | BARRIER | ENVIRONMENT | PENETRATION | time-resolved fluorescence spectroscopy | NANOPARTICLES | SPECTROSCOPY | EPIDERMIS | CORE-MULTISHELL NANOCARRIERS | TIGHT JUNCTION PROTEINS | Tight Junctions - metabolism | Dendrimers | Humans | Fluorescence | Skin - diagnostic imaging | Nanostructures | Fluorescent Dyes | Optical Imaging - methods | Drug Delivery Systems | Drugs | Fluorescence spectroscopy | Drug delivery systems | Dermatology | Formulae, receipts, prescriptions | Dermatologic agents | Skin | Investigations | Vehicles | Dyes | Stratum corneum | Photomicrographs | Fluorescent dyes | Nanomaterials | Labels | Drug delivery | Fluorescent indicators | Service life assessment | Clear cutting | Quenching | Penetration | Microscopy | Tagging | Clusters | Topical application | Localization | Nanotechnology | Quantitative analysis
FLIM | reconstructed human skin | drug delivery system | tight junctions | biomacromolecules | time‐resolved fluorescence spectroscopy | Reconstructed human skin | Biomacromolecules | Tight junctions | Time-resolved fluorescence spectroscopy | Drug delivery system | LOCALIZATION | DRUG-DELIVERY | MULTIDISCIPLINARY SCIENCES | BARRIER | ENVIRONMENT | PENETRATION | time-resolved fluorescence spectroscopy | NANOPARTICLES | SPECTROSCOPY | EPIDERMIS | CORE-MULTISHELL NANOCARRIERS | TIGHT JUNCTION PROTEINS | Tight Junctions - metabolism | Dendrimers | Humans | Fluorescence | Skin - diagnostic imaging | Nanostructures | Fluorescent Dyes | Optical Imaging - methods | Drug Delivery Systems | Drugs | Fluorescence spectroscopy | Drug delivery systems | Dermatology | Formulae, receipts, prescriptions | Dermatologic agents | Skin | Investigations | Vehicles | Dyes | Stratum corneum | Photomicrographs | Fluorescent dyes | Nanomaterials | Labels | Drug delivery | Fluorescent indicators | Service life assessment | Clear cutting | Quenching | Penetration | Microscopy | Tagging | Clusters | Topical application | Localization | Nanotechnology | Quantitative analysis
Journal Article
Handbook of Experimental Pharmacology, ISSN 0171-2004, 2010, Volume 197, Issue 197, pp. 435 - 468
Topical drug application is less prone to severe systemic side-effects than systemic application. Starting with the liposomes, various types of nanosized and...
Skin penetration | Cutaneous absorption | Drug carriers | Liposome | Polymer particles | Microemulsion | Solid lipid nanoparticle | Nanoparticles | Animals | Chemistry, Pharmaceutical - methods | Biological Transport | Dermatologic Agents - administration & dosage | Humans | Skin Absorption | Skin Diseases - drug therapy | Administration, Cutaneous | Drug Carriers - chemistry | Drug Delivery Systems
Skin penetration | Cutaneous absorption | Drug carriers | Liposome | Polymer particles | Microemulsion | Solid lipid nanoparticle | Nanoparticles | Animals | Chemistry, Pharmaceutical - methods | Biological Transport | Dermatologic Agents - administration & dosage | Humans | Skin Absorption | Skin Diseases - drug therapy | Administration, Cutaneous | Drug Carriers - chemistry | Drug Delivery Systems
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 2015, Volume 21, Issue 20, pp. 2784 - 2800
Dendritic nanoparticles have been developed with auspicious properties like high loading capacity for guest molecules, low polydispersity and tunable end...
Skin penetration | Dendrimers | Drug delivery systems | Tight junctions | Atopic dermatitis | Reconstructed human skin | Non-melanoma skin cancer | drug delivery systems | dendrimers | STRATUM-CORNEUM | BARRIER FUNCTION | skin penetration | non-melanoma skin cancer | ON-A-CHIP | ATOPIC-DERMATITIS | VITRO 3-DIMENSIONAL MODEL | IN-VITRO | SQUAMOUS-CELL CARCINOMA | PHARMACOLOGY & PHARMACY | reconstructed human skin | TIGHT JUNCTION PROTEINS | tight junctions | XENOBIOTIC METABOLISM CAPACITIES | CORE-MULTISHELL NANOTRANSPORTERS | Skin - anatomy & histology | Skin - microbiology | Skin Neoplasms - drug therapy | Skin - metabolism | Dendrimers - pharmacokinetics | Humans | Skin Absorption | Administration, Cutaneous | Skin Neoplasms - metabolism | Pharmaceutical Preparations - metabolism | Animals | Dermatitis, Atopic - drug therapy | Models, Biological | Pharmaceutical Preparations - chemistry | Dendrimers - chemistry | In Vitro Techniques | Pharmaceutical Preparations - administration & dosage | Dermatitis, Atopic - metabolism | Drug Delivery Systems - methods | Skin - pathology
Skin penetration | Dendrimers | Drug delivery systems | Tight junctions | Atopic dermatitis | Reconstructed human skin | Non-melanoma skin cancer | drug delivery systems | dendrimers | STRATUM-CORNEUM | BARRIER FUNCTION | skin penetration | non-melanoma skin cancer | ON-A-CHIP | ATOPIC-DERMATITIS | VITRO 3-DIMENSIONAL MODEL | IN-VITRO | SQUAMOUS-CELL CARCINOMA | PHARMACOLOGY & PHARMACY | reconstructed human skin | TIGHT JUNCTION PROTEINS | tight junctions | XENOBIOTIC METABOLISM CAPACITIES | CORE-MULTISHELL NANOTRANSPORTERS | Skin - anatomy & histology | Skin - microbiology | Skin Neoplasms - drug therapy | Skin - metabolism | Dendrimers - pharmacokinetics | Humans | Skin Absorption | Administration, Cutaneous | Skin Neoplasms - metabolism | Pharmaceutical Preparations - metabolism | Animals | Dermatitis, Atopic - drug therapy | Models, Biological | Pharmaceutical Preparations - chemistry | Dendrimers - chemistry | In Vitro Techniques | Pharmaceutical Preparations - administration & dosage | Dermatitis, Atopic - metabolism | Drug Delivery Systems - methods | Skin - pathology
Journal Article