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Journal of Biological Chemistry, ISSN 0021-9258, 02/1999, Volume 274, Issue 6, pp. 3705 - 3710
The in vitro fidelity of Escherichia coli DNA polymerase III holoenzyme (HE) is characterized by an unusual propensity for generating (−1)-frameshift... 
FREQUENCIES | COMPLEX | REPLICATION | ERRORS | FIDELITY | GENE | NUCLEOTIDE MISINCORPORATION | BACTERIOPHAGE-T4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXONUCLEASE | MUTATIONS | Templates, Genetic | Bacteriophage M13 - genetics | Base Pair Mismatch | Frameshift Mutation | Holoenzymes - metabolism | DNA Polymerase III - metabolism
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/1998, Volume 95, Issue 17, pp. 10020 - 10025
We have investigated the question whether during chromosomal DNA replication in Escherichia coli the two DNA strands may be replicated with differential... 
DNA replication | Lac operon | Plasmids | Proofreading | DNA | Genes | Alleles | Nucleotides | Genetic mutation | Chromosomes | MUTAGENESIS | GENE | MULTIDISCIPLINARY SCIENCES | REVERSE-TRANSCRIPTASE | MISMATCH REPAIR | MUTATOR MUTD5 | MECHANISMS | MUTATIONS | MISPAIR EXTENSION KINETICS | SACCHAROMYCES-CEREVISIAE | POLYMERASE-III HOLOENZYME | Chromosome replication | Genetic aspects | Research | Escherichia coli
Journal Article
Genetics, ISSN 0016-6731, 08/2002, Volume 161, Issue 4, p. 1363
  Deoxyribosyl-dihydropyrimido [4,5-c][1,2] oxazin-7-one (dP) is a potent mutagenic deoxycytidine-derived base analogue capable of pairing with both A and G,... 
Genetics | Bacteria | Mutation
Journal Article
FEMS Microbiology Reviews, ISSN 1574-6976, 11/2012, Volume 36, Issue 6, pp. 1105 - 1121
Journal Article
Molecular microbiology, ISSN 0950-382X, 4/2008, Volume 68, Issue 1, pp. 51 - 65
We have shown previously that lack of molybdenum cofactor (MoCo) in Escherichia coli leads to hypersensitivity to the mutagenic and toxic effects of N... 
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 02/2009, Volume 131, Issue 4, pp. 1550 - 1556
Journal Article
Genetics, ISSN 0016-6731, 08/2002, Volume 161, Issue 4, pp. 1363 - 1371
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 03/2008, Volume 190, Issue 5, p. 1730
  The dnaX36(TS) mutant of Escherichia coli confers a distinct mutator phenotype characterized by enhancement of transversion base substitutions and certain... 
Genotype & phenotype | Enzymes | E coli | DNA polymerase | Mutation
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 5/2004, Volume 186, Issue 9, pp. 2774 - 2780
The function of the θ subunit of Escherichia coli DNA polymerase III holoenzyme is not well established. θ is a tightly bound component of the DNA polymerase... 
Genetics and Molecular Biology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2006, Volume 281, Issue 50, pp. 38466 - 38471
The epsilon subunit of Escherichia coli DNA polymerase III possesses 3'-exonucleolytic proofreading activity. Within the Pol III core, epsilon is tightly bound... 
SYSTEM | DOMAIN | MUTANTS | PROTEIN | REPLICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | THETA-SUBUNIT | EXONUCLEASE | CRYSTALLOGRAPHY | TORSION ANGLE DYNAMICS | PROGRAM | Sequence Homology, Amino Acid | Amino Acid Sequence | DNA Polymerase III - chemistry | Escherichia coli - enzymology | Models, Molecular | Molecular Sequence Data | Protein Conformation
Journal Article
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 08/2002, Volume 184, Issue 16, p. 4449
  To investigate whether UV-induced mutations are created with equal efficiency on the leading and lagging strands of DNA replication, an assay system was... 
Ultraviolet radiation | Deoxyribonucleic acid | DNA | Genes | Mutation | Bacteriology
Journal Article
SCIENCE ADVANCES, ISSN 2375-2548, 09/2019, Volume 5, Issue 9, p. eaaw3915
A recent article in Science Advances described the striking discovery that the commensal Staphylococcus epidermidis strain MO34 displays antimicrobial and... 
YEAST SACCHAROMYCES-CEREVISIAE | MODIFIED PURINES | COFACTOR-DEPENDENT RESISTANCE | METABOLISM | GENETIC-CONTROL | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | TRIPHOSPHATE | BASE ANALOG 6-N-HYDROXYLAMINOPURINE | LYS2 GENE | MUTAGENIC SPECIFICITY | Adenine | Staphylococcus epidermidis | Mutagenesis | Saccharomyces cerevisiae | Humans | Neoplasms
Journal Article
Genetics, ISSN 0016-6731, 04/1998, Volume 148, Issue 4, p. 1579
Antimutators are mutant strains that have reduced mutation rates compared to the corresponding wild-type strain. Their existence, along with mutator mutants... 
Bacteria | Genetics | Mutation
Journal Article
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