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Molecular Therapy, ISSN 1525-0016, 08/2014, Volume 22, Issue 8, pp. 1405 - 1406
The stable retroviral integration of therapeutic transgene cassettes into patients' hematopoietic stem and progenitor cells enables gene therapy for various... 
TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | LEUKEMIA-VIRUS INTEGRATION | CHRONIC GRANULOMATOUS-DISEASE | LEDGF/P75 | GENOME | FAMILY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | GENE-THERAPY | TRANSCRIPTION START SITES | IMMUNODEFICIENCY
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2016, Volume 1448, pp. 23 - 39
Journal Article
Human Gene Therapy, ISSN 1043-0342, 10/2018, Volume 29, Issue 10, pp. 183 - 1097
Journal Article
Journal of Virology, ISSN 0022-538X, 12/2013, Volume 87, Issue 23, pp. 12721 - 12736
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2014, Volume 371, Issue 15, pp. 1407 - 1417
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2010, Volume 107, Issue 17, pp. 7805 - 7810
Journal Article
Human Gene Therapy, ISSN 1043-0342, 10/2017, Volume 28, Issue 10, pp. 897 - 913
The administration of ex vivo expanded natural killer (NK) cells as potential antitumor effector cells appears to be suitable for effector cell-based... 
Original Articles | chimeric antigen receptor-modified NK cells | acute myeloid leukemia | autologous feeder cells | IL-21 | interleukin-3 receptor subunit alpha (CD123) | closed GMPcompliant Prodigy system | MEDICINE, RESEARCH & EXPERIMENTAL | NATURAL-KILLER-CELLS | closed GMP-compliant Prodigy system | ALPHARETROVIRAL VECTORS | TUMOR-CELLS | ACUTE MYELOID-LEUKEMIA | CHIMERIC ANTIGEN RECEPTORS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IN-VIVO | GENETICS & HEREDITY | GENE-EXPRESSION | ACTIVATING RECEPTORS | ADOPTIVE IMMUNOTHERAPY | T-CELLS | Gene Expression | Transduction, Genetic | Cytokines - metabolism | Coculture Techniques | Feeder Cells | Humans | Cell Separation - methods | Cell Degranulation - immunology | Automation, Laboratory | Killer Cells, Natural - cytology | Flow Cytometry | K562 Cells | Cell Line, Tumor | Killer Cells, Natural - immunology | Killer Cells, Natural - drug effects | Cell Culture Techniques | Interleukins - pharmacology | Killer Cells, Natural - metabolism | Genetic Vectors | Transgenes | Cytotoxicity, Immunologic | Cell culture | Flow cytometry | Media (enrichment) | Separation | Media (culture) | Toxicity | Leukemia | Interleukin | Fluorescence | Effector cells | Cytotoxicity | Lymphocytes T | Leukocytes | Experiments | Optimization | Anticancer properties | CD69 antigen | Receptors | Interleukin 2 | CD123 antigen | Manufacturing | CD56 antigen | Expansion | Genetic modification | Target detection | Killing | Automation | CD137 antigen | Secretion | Myeloid leukemia | Good Manufacturing Practice | Health risks | CD3 antigen | T cell receptors | Tumor cell lines | Gene expression | Depletion | FasL protein | γ-Interferon | Degranulation | Culture media | Antitumor activity | Interferon | Prodigies | Acute myeloid leukemia | Apoptosis | Cancer | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2017, Volume 114, Issue 11, pp. E2243 - E2252
Rapid and efficient protocols to generate oligodendrocytes (OL) from human induced pluripotent stem cells (iPSC) are currently lacking, but may be a key... 
Myelination | Disease modeling | Forward patterning | Human iPSC | Oligodendrocytes | PROGENITOR CELLS | MUTANT TAU-PROTEIN | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | disease modeling | FRONTOTEMPORAL DEMENTIA | human iPSC | oligodendrocytes | PROCESS OUTGROWTH | PROGRESSIVE MULTIPLE-SCLEROSIS | MESSENGER-RNA | IN-VIVO | myelination | MOUSE SPINAL-CORD | DEVELOPMENTAL-CHANGES | forward patterning | Oligodendroglia - metabolism | Spinal Cord - metabolism | Oxidative Stress | Demyelinating Diseases - genetics | Humans | Transcriptome | tau Proteins - metabolism | Gene Expression Profiling | Demyelinating Diseases - metabolism | Neural Stem Cells - cytology | Spinal Cord - ultrastructure | Myelin Sheath - metabolism | Brain - metabolism | Myelin Basic Protein - genetics | Cell Differentiation - genetics | tau Proteins - genetics | Cell Death - genetics | Spinal Cord - pathology | Brain - ultrastructure | Oligodendroglia - cytology | Demyelinating Diseases - pathology | Induced Pluripotent Stem Cells - cytology | Cell Lineage - genetics | Disease Models, Animal | Induced Pluripotent Stem Cells - metabolism | Myelin Basic Protein - metabolism | Cells, Cultured | Ectopic Gene Expression | Transcription Factors - genetics | Transcription Factors - metabolism | Animals | Myelin Sheath - genetics | Biomarkers | Brain - pathology | Mice | Mutation | Neural Stem Cells - metabolism | Cluster Analysis | Cell proliferation | Physiological aspects | Dendritic cells | Observations | Stem cells | Gene expression | Rodents | Medical treatment | Index Medicus | Biological Sciences | PNAS Plus
Journal Article