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PLoS One, ISSN 1932-6203, 2009, Volume 4, Issue 8, pp. e6688 - e6688
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-4934, 2014, Volume 18, Issue 12, pp. 2488 - 2498
Impaired wound healing can lead to scarring, and aesthetical and functional problems. The cytoprotective haem oxygenase (HO) enzymes degrade haem into iron,... 
haem oxygenase | skin | wound healing | Skin | Wound healing | Haem oxygenase | MEDICINE, RESEARCH & EXPERIMENTAL | HEME-OXYGENASE-1 | CORNEAL INFLAMMATION | ANGIOGENESIS | REGENERATION | MOUSE | KERATINOCYTES | MATURATION | CELL BIOLOGY | REPAIR | STRESS | LACKING HEME OXYGENASE-2 | Immunohistochemistry | Tumor Necrosis Factor-alpha - metabolism | Chemokine CXCL11 - genetics | Heme Oxygenase-1 - metabolism | Skin - metabolism | Blood Vessels - metabolism | Heme Oxygenase (Decyclizing) - deficiency | Actins - metabolism | Ki-67 Antigen - metabolism | Gene Expression Profiling | Mice, 129 Strain | Skin - injuries | Actins - genetics | Heme Oxygenase-1 - genetics | Time Factors | Inflammation Mediators - metabolism | Wound Healing - genetics | Heme Oxygenase (Decyclizing) - genetics | Cell Proliferation - genetics | Mice, Inbred C57BL | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Mice, Knockout | Gene Expression Regulation, Enzymologic | Collagen - metabolism | Animals | Ki-67 Antigen - genetics | Cyclooxygenase 2 - metabolism | Chemokine CXCL11 - metabolism | Enzymes | Care and treatment | Wounds and injuries | Rodents | Oxidative stress | Cornea | Inflammatory response | Iron | Genotype & phenotype | Angiogenesis | Carbon monoxide | Genotypes | Antigens | Haem | Biliverdin | Cytokines | Blood vessels | Heme oxygenase (decyclizing) | Inflammation | Gene expression | Investigations | Oxygenase | Scars | Biopsy | Collagen | Mice | Original
Journal Article
Journal of Immunology, ISSN 0022-1767, 2002, Volume 169, Issue 1, pp. 507 - 514
Osteoarthritis has as main characteristics the degradation of articular cartilage and the formation of new bone at the joint edges, so-called osteophytes. In... 
RHEUMATOID-ARTHRITIS | POTENT INHIBITOR | GROWTH-FACTOR-BETA | MESSENGER-RNA | MURINE KNEE-JOINT | ARTICULAR-CARTILAGE | II RECEPTOR | MOUSE PATELLA | HUMAN BONE | IMMUNOLOGY | EXPRESSION | Immunohistochemistry | Recombinant Proteins - analysis | Chondrocytes - immunology | Protein-Serine-Threonine Kinases | Male | Matrix Metalloproteinase 1 - biosynthesis | Recombinant Proteins - biosynthesis | Transforming Growth Factor beta - biosynthesis | Tissue Inhibitor of Metalloproteinases - genetics | RNA, Messenger - biosynthesis | Transforming Growth Factor beta3 | Tissue Inhibitor of Metalloproteinases - biosynthesis | ADAMTS5 Protein | Chondrocytes - pathology | Transforming Growth Factor beta1 | Collagenases - genetics | Collagenases - biosynthesis | Solubility | Protein Isoforms - analysis | Blotting, Western | Cell Differentiation - immunology | Metalloendopeptidases - biosynthesis | Receptors, Transforming Growth Factor beta - biosynthesis | Mice | Metalloendopeptidases - genetics | Receptors, Transforming Growth Factor beta - physiology | Osteogenesis - immunology | Pichia - enzymology | Arthritis, Experimental - metabolism | Arthritis, Experimental - pathology | Chondrocytes - drug effects | Transforming Growth Factor beta - analysis | Receptor, Transforming Growth Factor-beta Type II | Transforming Growth Factor beta - antagonists & inhibitors | Osteoarthritis, Knee - immunology | Matrix Metalloproteinase 1 - genetics | Cartilage, Articular - chemistry | Procollagen N-Endopeptidase | Receptors, Transforming Growth Factor beta - analysis | Electrophoresis, Polyacrylamide Gel | Mice, Inbred C57BL | Osteogenesis - drug effects | ADAM Proteins | Arthritis, Experimental - immunology | Recombinant Proteins - pharmacology | ADAMTS4 Protein | Matrix Metalloproteinase 13 | Cartilage, Articular - pathology | Animals | Protein Isoforms - biosynthesis | Cell Differentiation - drug effects | Osteoarthritis, Knee - pathology | Cartilage, Articular - drug effects | Cartilage, Articular - immunology | Osteoarthritis, Knee - metabolism | Protein Isoforms - antagonists & inhibitors
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 01/2015, Volume 78, pp. 224 - 232
Heme oxygenase (HO)-1 is the inducible isoform of the heme-degrading enzyme HO, which is upregulated by multiple stress stimuli. HO-1 has major... 
Lipopolysaccharide | Bach1 | Inflammation | Mononuclear cells | Toll-like receptor | Heme oxygenase-1 | Toll-likereceptor | IMMUNE-RESPONSE | ACTIVATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | ENDOTOXIN | INDUCTION | SIGNALING PATHWAY | MONOXIDE | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | NITRIC-OXIDE | Gene Expression Regulation, Enzymologic - drug effects | Heme Oxygenase-1 - metabolism | Basic-Leucine Zipper Transcription Factors - metabolism | Endotoxemia - enzymology | Leukemia, Monocytic, Acute - pathology | Monocytes - cytology | Humans | Endotoxemia - pathology | Leukemia, Monocytic, Acute - enzymology | Heme Oxygenase-1 - genetics | Fanconi Anemia Complementation Group Proteins - metabolism | Real-Time Polymerase Chain Reaction | Leukemia, Monocytic, Acute - drug therapy | Leukocytes, Mononuclear - drug effects | Down-Regulation | Endotoxemia - drug therapy | RNA, Messenger - genetics | Fanconi Anemia Complementation Group Proteins - genetics | Basic-Leucine Zipper Transcription Factors - genetics | Macrophages - cytology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Macrophages - enzymology | Monocytes - drug effects | Monocytes - enzymology | Animals | Lipopolysaccharides - pharmacology | Leukocytes, Mononuclear - cytology | Leukocytes, Mononuclear - enzymology | Macrophages - drug effects | Mice | COX-2 inhibitors | Enzymes | RNA | Dendritic cells | Analysis | Leukemia | Heme | Gene expression | Mitogens | Index Medicus
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-4934, 2009, Volume 13, Issue 4, pp. 712 - 725
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2010, Volume 69, Issue Suppl 2, pp. A39 - A40
  Results Serum bilirubin levels and HO-1 western blot analysis suggested decreased HO-1 activity in SSc patients compared with healthy controls. 
Enzymes | Ligands | Tumor necrosis factor-TNF | Inflammation | Rodents
Journal Article
Rheumatology (Oxford, England), ISSN 1462-0324, 11/2016, Volume 55, Issue 11, p. 2066
Objective. SSc is a disease characterized by inflammation and fibrosis. Heme Oxygenase-1 (HO-1) is a haem-degrading enzyme that mediates resolution of... 
Systemic sclerosis | Pharmacology (medical) | Heme oxygenase-1 | Platelet factor 4/CXCL4 | Rheumatology | Toll-like receptors | Journal Article
Journal Article
Tissue Engineering, Part A: Tissue Engineering, ISSN 1937-3341, 03/2009, Volume 15, Issue 3, pp. 706 - 706
Cartilage has only a low regenerative potential, hence it is necessary to promote tissue engineering techniques to treat implications of degenerative... 
Journal Article
Tissue Engineering, Part A: Tissue Engineering, ISSN 1937-3341, 03/2009, Volume 15, Issue 3, pp. 703 - 703
Hypoxia is prevalent in native cartilage whereas in regular tissue culture cells are maintained under normoxic conditions. Reports exist to demonstrate the... 
Journal Article