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by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ...
Immunity, ISSN 1074-7613, 08/2019, Volume 51, Issue 2, pp. 411 - 412
Journal Article
Assistive technology : the official journal of RESNA, ISSN 1040-0435, 06/2019, pp. 1 - 7
Mobility is essential for activities of daily living and therapists should give priority to evaluate its effects in their client's performance. We aimed to... 
Journal Article
by Hmeljak, Julija and Sanchez-Vega, Francisco and Hoadley, Katherine A and Shih, Juliann and Stewart, Chip and Heiman, David and Tarpey, Patrick and Danilova, Ludmila and Drill, Esther and Gibb, Ewan A and Bowlby, Reanne and Kanchi, Rupa and Osmanbeyoglu, Hatice U and Sekido, Yoshitaka and Takeshita, Jumpei and Newton, Yulia and Graim, Kiley and Gupta, Manaswi and Gay, Carl M and Diao, Lixia and Gibbs, David L and Thorsson, Vesteinn and Iype, Lisa and Kantheti, Havish and Severson, David T and Ravegnini, Gloria and Desmeules, Patrice and Jungbluth, Achim A and Travis, William D and Dacic, Sanja and Chirieac, Lucian R and Galateau-Sallé, Françoise and Fujimoto, Junya and Husain, Aliya N and Silveira, Henrique C and Rusch, Valerie W and Rintoul, Robert C and Pass, Harvey and Kindler, Hedy and Zauderer, Marjorie G and Kwiatkowski, David J and Bueno, Raphael and Tsao, Anne S and Creaney, Jenette and Lichtenberg, Tara and Leraas, Kristen and Bowen, Jay and Felau, Ina and Zenklusen, Jean Claude and Akbani, Rehan and Cherniack, Andrew D and Byers, Lauren A and Noble, Michael S and Fletcher, Jonathan A and Robertson, A. Gordon and Shen, Ronglai and Aburatani, Hiroyuki and Robinson, Bruce W and Campbell, Peter and Ladanyi, Marc and Ally, Adrian and Anur, Pavana and Armenia, Joshua and Auman, J. Todd and Balasundaram, Miruna and Balu, Saianand and Baylin, Stephen B and Becich, Michael and Behrens, Carmen and Beroukhim, Rameen and Bielski, Craig and Bodenheimer, Tom and Bootwalla, Moiz S and Brooks, Denise and Byers, Lauren A and Cárcano, Flávio M and Carlsen, Rebecca and Carvalho, Andre L and Cheung, Dorothy and Chirieac, Lucian and Cho, Juok and Chuah, Eric and Chudamani, Sudha and Cibulskis, Carrie and Cope, Leslie and Crain, Daniel and Curley, Erin and De Rienzo, Assunta and DeFreitas, Timothy and Demchok, John A and Dhalla, Noreen and Dhir, Rajiv and Feldman, Michael and Ferguson, Martin L and Fukuda, Shiro and Gabriel, Stacey B and Sallé, Françoise Galateau and Gao, Jianjiong and Gardner, Johanna and Gastier-Foster, Julie M and ... and TCGA Res Network and TCGA Research Network
Cancer Discovery, ISSN 2159-8274, 12/2018, Volume 8, Issue 12, pp. 1549 - 1565
Malignant pleural mesothelioma (MPM) is a highly lethal cancer of the lining of the chest cavity. To expand our understanding of MPM, we conducted a... 
CELLS | IMMUNE-CHECKPOINT | GENE | ONCOLOGY | TUMOR-SUPPRESSOR | WHOLE-EXOME | MUTATIONS | CANCER | EXPRESSION | BAP1 | DELETION
Journal Article
by Wang, Zhining and Wang, Linghua and Wang, Min and Wang, Jing and Wang, Jioajiao and Wang, Yumeng and Wang, Timothy and Xu, Xiaoyan and Maglic, Dejan and Dill, Michael T and Mojumdar, Kamalika and Ng, Patrick Kwok-Shing and Ng, Kwok-Shing and Jeong, Kang Jin and Tsang, Yiu Huen and Moreno, Daniela and Bhavana, Venkata Hemanjani and Peng, Xinxin and Ge, Zhongqi and Chen, Zhongyuan and Chen, Amy and Chen, Chu and Chen, Hu and Li, Jun and Li, Wei and Zhang, Jiexin and Zhang, Jiashan (Julia) and Zhang, Lizhi and Zhang, Huiwen and Zhang, Hongzheng and Zhang, Wei and Zhang, Hongxin and Zhang, Hailei and Han, Yi and Han, Leng and Du, Di and Creighton, Chad J and Mills, Gordon B and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Yang, Liming and Yang, Ju Dong and Yang, Ian and Yang, Hannah and Zenklusen, Jean C and Chudamani, Sudha and Liu, Wenbin and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Michael and Miller, Judy and Miller, Christopher A and Reynolds, Sheila and Shmulevich, Ilya and Thorsson, Vesteinn and Akbani, Rehan and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Liang, Han and Ling, Shiyun and Lu, Yiling and Rao, Arvind and Ryan, Michael and Weinstein, John N and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cell Reports, ISSN 2211-1247, 10/2018, Volume 25, Issue 5, pp. 1304 - 1317.e5
Hippo signaling has been recognized as a key tumor suppressor pathway. Here, we perform a comprehensive molecular characterization of 19 Hippo core genes in... 
miRNA regulation | YAP | tumor subtype | TAZ | TCGA | prognostic power | pan-cancer analysis | driver mutation | pathway activity | BREAST-CANCER | CELLS | TUMOR PROGRESSION | GENE | ORGAN SIZE CONTROL | PANCREATIC-CANCER | GROWTH | PROMOTES | CELL BIOLOGY
Journal Article
by Korkut, Anil and Zaidi, Sobia and Kanchi, Rupa S and Rao, Shuyun and Gough, Nancy R and Gough, Nancy R and Schultz, Andre and Li, Xubin and Lorenzi, Philip L and Berger, Ashton C and Berger, Ashton C and Robertson, Gordon and Kwong, Lawrence N and Datto, Mike and Roszik, Jason and Ling, Shiyun and Ling, Shiyun and Ravikumar, Visweswaran and Manyam, Ganiraju and Rao, Arvind and Shelley, Simon and Liu, Yuexin and Liu, Yuexin and Ju, Zhenlin and Hansel, Donna and Hansel, Donna and de Velasco, Guillermo and de Velasco, Guillermo and Pennathur, Arjun and Andersen, Jesper B and O'Rourke, Colm J and Ohshiro, Kazufumi and Jogunoori, Wilma and Jogunoori, Wilma and Nguyen, Bao-Ngoc and Li, Shulin and Li, Shulin and Osmanbeyoglu, Hatice U and Osmanbeyoglu, Hatice U and Ajani, Jaffer A and Ajani, Jaffer A and Mani, Sendurai A and Houseman, Andres and Wiznerowicz, Maciej and Wiznerowicz, Maciej and Chen, Jian and Chen, Jian and Gu, Shoujun and Ma, Wencai and Zhang, Jiexin and Tong, Pan and Cherniack, Andrew D and Cherniack, Andrew D and Deng, Chuxia and Deng, Chuxia and Resar, Linda and Resar, Linda and Caesar-Johnson, Samantha J and Weinstein, John N and Demchok, John A and Felau, Ina and Mishra, Lopa and Kasapi, Melpomeni and Akbani, Rehan and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Zhining and Yang, Liming and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Chudamani, Sudha and Liu, Jia and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Zhang, Hailei and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cell Systems, ISSN 2405-4712, 10/2018, Volume 7, Issue 4, pp. 422 - 437.e7
We present an integromic analysis of gene alterations that modulate transforming growth factor β (TGF-β)-Smad-mediated signaling in 9,125 tumor samples across... 
TGF-β pathway | transcription | DNA methylation | microRNA | TGF-β | cancer | Pan-Cancer | mutation hotspot | TCGA | The Cancer Genome Atlas | ARRAY | MECHANISM | TUMOR SUPPRESSION | SEARCH | BIOCHEMISTRY & MOLECULAR BIOLOGY | PATTERNS | HMGA2 | GENERATION | MUTATIONS | CELL BIOLOGY | mutation | PanCancer | The Cancer Genome Atlas (TCGA)
Journal Article
by Kahles, André and Lehmann, Kjong-Van and Toussaint, Nora C and Hüser, Matthias and Stark, Stefan G and Sachsenberg, Timo and Stegle, Oliver and Kohlbacher, Oliver and Sander, Chris and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jing and Wang, Timothy and Wang, Min and Wang, Jioajiao and Wang, Zhining and Wang, Linghua and Yang, Ju Dong and Yang, Liming and Yang, Ian and Yang, Hannah and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Hailei and Zhang, Wei and Zhang, Jiexin and Zhang, Hongxin and Zhang, Lizhi and Zhang, Hongzheng and Chudamani, Sudha and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Liu, Wenbin and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Christopher A and Miller, Michael and Miller, Judy and Reynolds, Sheila and Shmulevich, Ilya and Thorsson, Vesteinn and Akbani, Rehan and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Li, Jun and Li, Wei and Liang, Han and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind and Ryan, Michael and Weinstein, John N and Abeshouse, Adam and Armenia, Joshua and Chakravarty, Debyani and Chatila, Walid K and de Bruijn, Ino and Gao, Galen F and Gao, Jianjiong and Gross, Benjamin E and Heins, Zachary J and Kundra, Ritika and La, Konnor and Ladanyi, Marc and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cancer Cell, ISSN 1535-6108, 08/2018, Volume 34, Issue 2, pp. 211 - 224.e6
Journal Article