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Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 05/2019, Volume 144, Issue 9, pp. 2347 - 2354
Journal Article
Drugs and Aging, ISSN 1170-229X, 04/2019, Volume 36, Issue 4, pp. 379 - 385
BackgroundOlder patients with metastatic castration-resistant prostate cancer (mCRPC) may be more prone to chemotherapy-induced hematological toxicity, but... 
THERAPY | PHARMACOKINETICS | FEBRILE NEUTROPENIA | MEN | PHARMACOLOGY & PHARMACY | UPDATE | CHEMOTHERAPY | GERIATRICS & GERONTOLOGY
Journal Article
British Journal of Cancer, ISSN 0007-0920, 02/2019, Volume 120, Issue 3, pp. 286 - 293
BACKGROUND: This phase I, open-label, dose-escalation study evaluated the safety, pharmacokinetics and pharmacodynamics of combination therapy with the HDM2... 
ACTIVATION | P53 PATHWAY | ONCOLOGY | RG7112 | Toxicity | Creatine kinase | p53 Protein | Metastasis | Creatine | Metastases | Anticancer properties | Vomiting | Safety engineering | Safety | Drug dosages | Thrombocytopenia | Pharmacodynamics | MEK inhibitors | Diarrhea | Nausea | Pharmacology | Patients | Inhibitors | Minimum inhibitory concentration | Biomarkers | Solid tumors | Mutation | Pharmacokinetics | Tumors | Index Medicus
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 12/2018, Volume 84, Issue 12, pp. 2761 - 2769
Aims This study aimed to determine the effect of food intake on uracil and dihydrouracil plasma levels. These levels are a promising marker for... 
uridine | uracil | dihydropyrimidine dehydrogenase | food‐effect study | dihydrouracil | food-effect study | RATIOS | SAFETY | URIDINE PHOSPHORYLASE | SEVERE TOXICITY | FLUOROURACIL | CLINICAL-RELEVANCE | 5-FLUOROURACIL | GENE | COLORECTAL-CANCER | PHARMACOLOGY & PHARMACY | 5-FU | Pyrimidines | Original
Journal Article
The Lancet Oncology, ISSN 1470-2045, 02/2019, Volume 20, Issue 2, pp. e67 - e67
Journal Article
Journal Article
Cytometry Part A, ISSN 1552-4922, 10/2019, Volume 95, Issue 10, pp. 1053 - 1065
We report the development and validation of a 12 parameter immunofluorescence flow cytometry method for the sensitive determination of cell concentrations,... 
PD‐1 receptor occupancy | pembrolizumab | immune cell subsets | pharmacodynamic | nivolumab | immunotherapy | Flow cytometry | Dendritic cells | CD8 antigen | Centrifugation | Parameter sensitivity | CD4 antigen | Infusion | Monocytes | Killer cells | Pembrolizumab | Linearity | Occupancy | Peripheral blood | Natural killer cells | Immunofluorescence | Immune system
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 09/2019, Volume 25, Issue 18, pp. 5466 - 5474
Purpose: Oral bioavailability of docetaxel is poor. Absorption could be improved by development of pharmaceutical formulations based on docetaxel solid... 
PHARMACOKINETICS | METABOLISM | ONCOLOGY | PHARMACEUTICAL DEVELOPMENT | SOLID DISPERSION | FORMULATION | CANCER | BIOAVAILABILITY | P-GLYCOPROTEIN
Journal Article
Cancer Research, ISSN 0008-5472, 05/2015, Volume 75, Issue 9 Supplement, pp. SF1-2 - SF1-2
Journal Article
Journal Article
Cancer research, ISSN 0008-5472, 2004, Volume 64, Issue 16, pp. 5804 - 5811
Journal Article