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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2008, Volume 105, Issue 30, pp. 10519 - 10524
Journal Article
Nature Cell Biology, ISSN 1465-7392, 11/2013, Volume 15, Issue 11, p. 1351
  In patients, non-proliferative disseminated tumour cells (DTCs) can persist in the bone marrow (BM) while other organs (such as lung) present growing... 
Head and neck cancer | Development and progression | Genetic aspects | Cellular signal transduction | Transforming growth factors | Properties | Testing
Journal Article
Cancer Research, ISSN 0008-5472, 02/2009, Volume 69, Issue 4, pp. 1545 - 1552
The proteasome inhibitor bortezomib (Velcade) effectively eradicates multiple myeloma (MM) cells, partly by activating endoplasmic reticulum (ER) stress... 
CARCINOMA-CELLS | INITIATION-FACTOR 2-ALPHA | UNFOLDED PROTEIN RESPONSE | ONCOLOGY | INDUCED APOPTOSIS | GROWTH ARREST | ER STRESS | IN-VIVO | ENDOPLASMIC-RETICULUM STRESS | TRANSLATION | TUMOR-GROWTH
Journal Article
Haematologica, ISSN 0390-6078, 08/2019, p. haematol.2019.224774
Children with Down syndrome and acute lymphoblastic leukemia often suffer from severe toxicities during treatment, especially with high-dose methotrexate.... 
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 277 - 277
Abstract Introduction: CD19 antibody therapy may represent an attractive treatment option in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL).... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2008, Volume 105, Issue 30, p. 10519
  The pathways that allow quiescent disseminated cancer cells to survive during prolonged dormancy periods are unknown. Here, we identify the transcription... 
Proteins | Signal transduction | Cells | Cancer | Tumors
Journal Article
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 07/2008, Volume 105, Issue 30, pp. 10519 - 10524
The pathways that allow quiescent disseminated cancer cells to survive during prolonged dormancy periods are unknown. Here, we identify the transcription... 
Journal Article
Blood, ISSN 0006-4971, 01/2015, Volume 125, Issue 5, pp. 820 - 830
Patients with t(1; 19)-positive acute lymphoblastic leukemia (ALL) are prone to central nervous system (CNS) relapses, and expression of theTAM(Tyro3, Axl, and... 
RAD001 EVEROLIMUS | NATURAL-KILLER-CELLS | ACTIVATION | BONE-MARROW | THERAPEUTIC TARGET | IN-VIVO | ACUTE MYELOID-LEUKEMIA | TAM RECEPTORS | HEMATOLOGY | EXPRESSION | MARROW STROMAL CELLS | Methotrexate - pharmacology | RNA, Small Interfering - genetics | Translocation, Genetic | Pyrazoles - therapeutic use | Central Nervous System - metabolism | Coculture Techniques | Humans | Galectin 3 - metabolism | Central Nervous System - pathology | Case-Control Studies | Proto-Oncogene Proteins c-akt - genetics | Glioma - metabolism | Glioma - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Chromosomes, Human, Pair 1 | Glioma - pathology | c-Mer Tyrosine Kinase | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Antimetabolites, Antineoplastic - pharmacology | Female | Tumor Cells, Cultured | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Proto-Oncogene Proteins c-akt - metabolism | Child | Astrocytes - cytology | Proto-Oncogene Proteins - metabolism | Astrocytes - drug effects | Proto-Oncogene Proteins - antagonists & inhibitors | Signal Transduction | Cell Survival | Proto-Oncogene Proteins - genetics | Gene Expression Regulation, Leukemic | Galectin 3 - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Chromosomes, Human, Pair 19 | Animals | Receptor Protein-Tyrosine Kinases - genetics | Pyrimidines - therapeutic use | Central Nervous System - drug effects | Mice | Primary Cell Culture | Astrocytes - metabolism | RNA, Small Interfering - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Blood, ISSN 0006-4971, 12/2016, Volume 128, Issue 22, pp. 1835 - 1835
Abstract Introduction: Three unconjugated CD20 antibodies have been approved for the treatment of lymphoma patients. All three are of human IgG1 isotype, but... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 10/2018, Volume 132, Issue 15, pp. 1614 - 1617
Central nervous system (CNS) involvement in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is rarely detected at initial presentation. 1... 
SURVIVAL | BLASTS | MARKERS | RISK | RECEPTOR | CENTRAL-NERVOUS-SYSTEM | PROLIFERATION | HEMATOLOGY | CHILDHOOD | EXPRESSION | CHILDREN | 100 | Letter to
Journal Article
OncoImmunology, ISSN 2162-4011, 08/2018, Volume 7, Issue 8, p. e1448331
CD19 immunotherapies based on T cells opened new avenues in the treatment of pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). However, Fc... 
CAR T cells | Acute lymphoblastic leukemia | bispecific antibodies | CD19 | Fc engineering | ADULT PATIENTS | MULTICENTER | LINEAGE SWITCH | PHASE-II | IMMUNOLOGY | CANCER | IN-VITRO | THERAPY | ONCOLOGY | BLINATUMOMAB | T-CELLS | XENOGRAFTS
Journal Article
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