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Science, ISSN 0036-8075, 11/2004, Volume 306, Issue 5701, pp. 1506 - 1507
Journal Article
Nature, ISSN 0028-0836, 09/2010, Volume 467, Issue 7315, pp. 596 - 599
B-RAF is the most frequently mutated protein kinase in human cancers. The finding that oncogenic mutations in BRAF are common in melanoma, followed by the... 
ACTIVATION | PATHWAY | MULTIDISCIPLINARY SCIENCES | MUTATION | KERATOACANTHOMAS | SENSITIVITY | SENESCENCE | SORAFENIB | HUMAN CANCER | PROGRESSION | BRAF(V600E) | Humans | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Macaca fascicularis | Melanoma - enzymology | Substrate Specificity | Positron-Emission Tomography | Extracellular Signal-Regulated MAP Kinases - metabolism | Indoles - administration & dosage | Neoplasm Metastasis | Melanoma - genetics | Phosphorylation - drug effects | Mutant Proteins - antagonists & inhibitors | Proto-Oncogene Proteins B-raf - metabolism | Proto-Oncogene Proteins B-raf - chemistry | Sulfonamides - chemistry | Mutant Proteins - genetics | Models, Molecular | Rats | Mutant Proteins - metabolism | Melanoma - pathology | Mutation - genetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Xenograft Model Antitumor Assays | Animals | Indoles - adverse effects | MAP Kinase Signaling System - drug effects | Sulfonamides - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Mutant Proteins - chemistry | Alleles | Dogs | Sulfonamides - adverse effects | Indoles - therapeutic use | Indoles - chemistry | Sulfonamides - administration & dosage | Control | Gene mutations | Melanoma | Development and progression | Genetic aspects | Research | Health aspects | Protein kinases | Cancer | Proteins | Mutation | Kinases | Rodents | Index Medicus | targeted therapy | melanoma | BRAF | PLX4032 | biomarker | oncogene
Journal Article
Cell, ISSN 0092-8674, 09/2013, Volume 154, Issue 6, pp. 1180 - 1181
Journal Article
Molecular Cell, ISSN 1097-2765, 09/2013, Volume 51, Issue 5, pp. 553 - 554
Journal Article
Cancer Cell, ISSN 1535-6108, 09/2013, Volume 24, Issue 3, pp. 273 - 274
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by Knouff, Christopher W and Kent, Kenneth M and John, Ulrich and Mathew, Christopher G and Thomson, Wendy and Kesaniemi, Antero and Rader, Daniel J and Bakke, Per and Pillai, Sreekumar G and Huffman, Jennifer and Mooser, Vincent and Kooner, Jaspal and Busonero, Fabio and Scheet, Paul and Lamina, Claudia and Gulsvik, Amund and Waksman, Ron and Epstein, Stephen and Grabe, Hans Jörgen and Hayward, Caroline and Campbell, Harry and Matthai, William and Wittig, Michael and Vincent, John B and Wild, Sarah H and Samani, Nilesh J and Farmer, Anne and Ahmad, Tariq and Anderson, Carl A and Terracciano, Antonio and Francks, Clyde and Zhao, Jing Hua and Teumer, Alexander and Polasek, Ozren and Loos, Ruth J F and Chambers, John C and Devaney, Joseph M and Lucae, Susanne and Preisig, Martin and Balmforth, Anthony J and Qu, Liming and Pichard, Augusto D and Barroso, Inês and Caulfield, Mark and Petersmann, Astrid and McPherson, Ruth and Franke, Andre and McGuffin, Peter and Abecasis, Gonçalo R and Völzke, Henry and Ising, Marcus and Thompson, John R and Schlessinger, David and Rujescu, Dan and Munroe, Patricia B and Burnett, Mary Susan and Vitart, Veronique and Mahley, Robert and Eyre, Steve and Satsangi, Jack and Worthington, Jane and Wareham, Nicholas J and Dominiczak, Anna and Day, Richard and Xiao, Xiangjun and Middleton, Lefkos and Clair, David St and Wichmann, H-Erich and Reilly, Muredach P and Khaw, Kay-Tee and Barton, Anne and Rawal, Rajesh and Berrettini, Wade and Yuan, Xin and Tozzi, Federica and Kennedy, James L and Waeber, Gérard and Wright, Alan F and Wright, Benjamin J and Wilensky, Robert and Farrall, Martin and Parkes, Miles and Dahmen, Norbert and Campbell, Susan and Matthews, Keith and Strauss, John and Horstmann, Sonja and Lindsay, Joseph M and Wilson, James F and Zgaga, Lina and Barter, Philip and Grundy, Scott and Waterworth, Dawn M and Schäfer, Arne and Rudan, Igor and Hakonarson, Hakon H and Marchini, Jonathan and Uda, Manuela and Li, Mingyao and Vollenweider, Peter and ... and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and The Wellcome Trust Case Control Consortium
Nature Genetics, ISSN 1061-4036, 05/2010, Volume 42, Issue 5, pp. 436 - 440
Journal Article
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. PL04-03 - PL04-03
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Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 11, pp. 1173 - 1186
Journal Article
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Nature: international weekly journal of science, ISSN 0028-0836, 05/2016, Volume 533, Issue 7604, pp. 539 - 542
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