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Methods (San Diego, Calif.), ISSN 1046-2023, 02/2019
Apart from being storage devices for genetic information, nucleic acids can provide regulatory structures through evolutionarily optimized sequences. The... 
Journal Article
Nature Communications, ISSN 2041-1723, 10/2016, Volume 7, Issue 1, p. 13166
The COP9 signalosome (CSN) is a central component of the activation and remodelling cycle of cullin-RING E3 ubiquitin ligases (CRLs), the largest enzyme family... 
UBIQUITIN LIGASE COMPLEX | JAB1/CSN5 | CELL LYMPHOMA | SUBSTRATE | MULTIDISCIPLINARY SCIENCES | PROTEASOME | SCF | F-BOX PROTEINS | DEGRADATION | BORTEZOMIB | DEUBIQUITINATION
Journal Article
Bioconjugate chemistry, ISSN 1043-1802, 08/2016, Volume 27, Issue 8, pp. 1959 - 1959
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 07/2016, Volume 27, Issue 7, p. 1559
  Protein-DNA hybrids have become increasingly popular molecular building blocks in bionanotechnology and single-molecule studies to synergistically combine... 
Proteins | Biotechnology | Spectrum analysis | Molecular chemistry | Nanotechnology | Deoxyribonucleic acid--DNA
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 07/2016, Volume 27, Issue 7, pp. 1559 - 1559
Protein-DNA hybrids have become increasingly popular molecular building blocks in bionanotechnology and single-molecule studies to synergistically combine the... 
Journal Article
Current Opinion in Structural Biology, ISSN 0959-440X, 10/2019, Volume 58, pp. 124 - 137
Membrane proteins fulfil a plethora of vital functions, are major drug targets, and are implicated in many diseases. Their importance, however, is in no way... 
Journal Article
Biophysical Journal, ISSN 0006-3495, 2006, Volume 90, Issue 4, pp. L33 - L35
The protein folding process is described as diffusion on a high-dimensional energy landscape. Experimental data showing details of the underlying energy... 
STRENGTH | PROTEIN | BIOPHYSICS | ADHESION BONDS | SPECTROSCOPY | Models, Molecular | Thermodynamics | Proteins - chemistry | Protein Folding | Molecules | Bioenergetics | Protein folding | Experiments | Biophysical Letters
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 10/2018, Volume 430, Issue 22, pp. 4592 - 4602
AAA+ proteases are essential players in cellular pathways of protein degradation. Elucidating their conformational behavior is key for understanding their... 
single-molecule FRET | ATP-dependent proteases | conformational dynamics | protein degradation | vesicle encapsulation | Proteases | Proteolysis | Adenosine triphosphatase | Force and energy
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2004, Volume 101, Issue 19, pp. 7299 - 7304
We use single-molecule force spectroscopy to study the kinetics of unfolding of the small protein ubiquitin. Upon a step increase in the stretching force, a... 
Cantilevers | Histograms | Spectroscopy | Molecules | Biological Sciences | RNA | Ubiquitins | Protein unfolding | Data lines | Kinetics | Polyproteins | ADHESION | PROTEIN | SPECTROSCOPY | TITIN | STABILITY | MULTIDISCIPLINARY SCIENCES | IMMUNOGLOBULIN DOMAINS | FIBRONECTIN | DYNAMICS | MICROSCOPY | LIFETIME | Microscopy, Atomic Force | Probability | Ubiquitin - chemistry | Ubiquitin | Research
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2016, Volume 113, Issue 27, pp. 7533 - 7538
Journal Article
eLife, ISSN 2050-084X, 01/2019, Volume 8
Most replicative helicases are hexameric, ring-shaped motor proteins that translocate on and unwind DNA. Despite extensive biochemical and structural... 
DnaG | single-molecule FRET | structural biology | DnaB | none | G40P | molecular biophysics | TRANSLOCATION | PROTEIN | MECHANISM | SPECIFICITY | MOLECULE | MECHANOCHEMISTRY | BIOLOGY | HYDROLYSIS | REPLICATIVE HELICASE | ATP | REVEALS | Hydrolysis | DNA helicase | Proteins | Enzymes | Primase | Unwinding | Biophysics | Deoxyribonucleic acid--DNA | Binding sites
Journal Article