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Molecular Cancer Research, ISSN 1541-7786, 06/2017, Volume 15, Issue 6, pp. 753 - 764
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 8, pp. e12031 - e12031
Vascular endothelial growth factor (VEGF) is critical for physiological and pathological angiogenesis. Within the tumor microenvironment, VEGF functions as an... 
BREAST-CANCER | ANTIANGIOGENIC THERAPY | IMMUNE CELL INFILTRATION | METASTASIS | BIOLOGY | NITRIC-OXIDE | MICE | MEDIATED ANGIOGENESIS | TUMOR-GROWTH | RECEPTOR TYROSINE KINASE | ENDOTHELIAL GROWTH-FACTOR | Antibodies, Monoclonal - toxicity | Humans | Microvessels - metabolism | Substrate Specificity | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Vascular Endothelial Growth Factor A - metabolism | Antineoplastic Agents - toxicity | Lymphatic Vessels - drug effects | Lymphatic Vessels - metabolism | Female | Antineoplastic Agents - pharmacology | Phosphorylation - drug effects | Antibodies, Monoclonal - immunology | Binding, Competitive | Antineoplastic Agents - immunology | Antibodies, Monoclonal - pharmacology | Microvessels - drug effects | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor A - immunology | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Animals | Signal Transduction - drug effects | Endothelial Cells - cytology | Cell Line, Tumor | Mice | Endothelial Cells - drug effects | Monoclonal antibodies | Permeability | Vascular endothelial growth factor | Health aspects | Enzyme-linked immunosorbent assay | Biopharmaceutics | Tumors | Endothelium | Therapy | Animal models | Physiological effects | Research parks | Toxicity | Clinical trials | Neuropilin | Oncology | Activation | Metastasis | Assaying | Cancer therapies | Cell surface | Blood | Anticancer properties | Angiogenesis | Receptors | Cell activation | Antitumor agents | Rodents | Surgery | Bone marrow | Protein-tyrosine kinase receptors | Blood pressure | Tumorigenesis | Trends | Protein-tyrosine kinase | Binding | Urine | Tyrosine | Hypertension | Lymphatic system | Immunoglobulins | Cell survival | Histology | Chromatography | Endothelial cells | Signaling | Survival factor | Receptor mechanisms | Pharmaceuticals | Index Medicus
Journal Article
Journal Article
by Ager, Casey and Reilley, Matthew and Nicholas, Courtney and Bartkowiak, Todd and Jaiswal, Ashvin and Curran, Michael and Albershardt, Tina C and Bajaj, Anshika and Archer, Jacob F and Reeves, Rebecca S and Ngo, Lisa Y and Berglund, Peter and ter Meulen, Jan and Denis, Caroline and Ghadially, Hormas and Arnoux, Thomas and Chanuc, Fabien and Fuseri, Nicolas and Wilkinson, Robert W and Wagtmann, Nicolai and Morel, Yannis and Andre, Pascale and Atkins, Michael B and Carlino, Matteo S and Ribas, Antoni and Thompson, John A and Choueiri, Toni K and Hodi, F. Stephen and Hwu, Wen-Jen and McDermott, David F and Atkinson, Victoria and Cebon, Jonathan S and Fitzharris, Bernie and Jameson, Michael B and McNeil, Catriona and Hill, Andrew G and Mangin, Eric and Ahamadi, Malidi and van Vugt, Marianne and van Zutphen, Mariëlle and Ibrahim, Nageatte and Long, Georgina V and Gartrell, Robyn and Blake, Zoe and Simoes, Ines and Fu, Yichun and Saito, Takuro and Qian, Yingzhi and Lu, Yan and Saenger, Yvonne M and Budhu, Sadna and De Henau, Olivier and Zappasodi, Roberta and Schlunegger, Kyle and Freimark, Bruce and Hutchins, Jeff and Barker, Christopher A and Wolchok, Jedd D and Merghoub, Taha and Burova, Elena and Allbritton, Omaira and Hong, Peter and Dai, Jie and Pei, Jerry and Liu, Matt and Kantrowitz, Joel and Lai, Venus and Poueymirou, William and MacDonald, Douglas and Ioffe, Ella and Mohrs, Markus and Olson, William and Thurston, Gavin and Capasso, Cristian and Frascaro, Federica and Carpi, Sara and Tähtinen, Siri and Feola, Sara and Fusciello, Manlio and Peltonen, Karita and Martins, Beatriz and Sjöberg, Madeleine and Pesonen, Sari and Ranki, Tuuli and Kyruk, Lukasz and Ylösmäki, Erkko and Cerullo, Vincenzo and Cerignoli, Fabio and Xi, Biao and Guenther, Garret and Yu, Naichen and Muir, Lincoln and Zhao, Leyna and Abassi, Yama and Cervera-Carrascón, Víctor and Siurala, Mikko and Santos, João and Havunen, Riikka and Parviainen, Suvi and Hemminki, Akseli and ...
Journal for ImmunoTherapy of Cancer, ISSN 2051-1426, 11/2016, Volume 4, Issue S1
Journal Article
05/2018
Disclosed are human antibodies that specifically inhibit VEGF binding to only one (VEGFR2) of the two primary VEGF receptors. The antibodies effectively... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | METALLURGY | PEPTIDES | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
08/2016
Disclosed are human antibodies that specifically inhibit VEGF binding to only one (VEGFR2) of the two primary VEGF receptors. The antibodies effectively... 
HYGIENE | METALLURGY | PEPTIDES | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
05/2016
Un anticuerpo aislado que se une al VEGF y que comprende al menos una región variable de cadena pesada que comprende tres CDR y al menos una región variable de... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | METALLURGY | PEPTIDES | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
05/2016
Docment2-4/10/2013 Disclosed are human antibodies that specifically inhibit VEGF binding to only one (VEGFR2) of the two primary VEGF receptors. The antibodies... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
08/2014
Disclosed are human antibodies that specifically inhibit VEGF binding to only one (VEGFR2) of the two primary VEGF receptors. The antibodies effectively... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | METALLURGY | PEPTIDES | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
Cancer Immunology Research, ISSN 2326-6066, 11/2016, Volume 4, Issue 11 Supplement, pp. B119 - B119
Journal Article
09/2013
The invention relates to an isolated antibody that specifically binds to VEGF and effectively inhibits angiogenesis and induces tumor regression. The invention... 
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS | HYGIENE | METALLURGY | PEPTIDES | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
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