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Science, ISSN 0036-8075, 11/2004, Volume 306, Issue 5700, pp. 1383 - 1386
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2011, Volume 17, Issue 9, pp. 1076 - 1085
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 12/2019, Volume 33, Issue 12, pp. 13808 - 13824
N-acetylaspartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A and aspartate. In the brain, NAA is considered an... 
TOXICITY ASSESSMENT | ATGL-MEDIATED LIPOLYSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | adipose tissue | FOLLOW-UP | insulin secretion | BROWN ADIPOSE-TISSUE | DEFICIENCY | NAA | CELL BIOLOGY | MAGNETIC-RESONANCE-SPECTROSCOPY | GLUCOSE | BIOLOGY | BETA-CELL LINE | acetyl-CoA | L-ASPARTIC ACID | energy homeostasis | BRAIN | Research
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2010, Volume 285, Issue 10, pp. 7300 - 7311
Journal Article
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2012, Volume 15, Issue 5, pp. 691 - 702
Numerous studies in humans link a nonsynonymous genetic polymorphism (I148M) in adiponutrin (ADPN) to various forms of fatty liver disease and liver cirrhosis.... 
ADIPOSE TRIGLYCERIDE LIPASE | COMPARATIVE GENE IDENTIFICATION-58 | LIPID-METABOLISM | MESSENGER-RNA EXPRESSION | FATTY LIVER-DISEASE | FAMILY-MEMBERS | ENZYMES | ENDOCRINOLOGY & METABOLISM | PNPLA3 | CONGENITAL GENERALIZED LIPODYSTROPHY | CHANARIN-DORFMAN-SYNDROME | CELL BIOLOGY | 1-Acylglycerol-3-Phosphate O-Acyltransferase - genetics | Lysophospholipids - metabolism | Up-Regulation | Lipids - genetics | Humans | Cercopithecus aethiops | Acyl Coenzyme A - genetics | Male | Lipids - biosynthesis | Acyltransferases - metabolism | Acyltransferases - genetics | 1-Acylglycerol-3-Phosphate O-Acyltransferase - metabolism | Cysteine Endopeptidases - metabolism | Liver - drug effects | Lipid Metabolism - genetics | Membrane Proteins - metabolism | Dietary Sucrose - metabolism | Phospholipids - metabolism | Acyl Coenzyme A - metabolism | CHO Cells | Fatty Liver - genetics | Phosphatidic Acids - genetics | Cricetinae | Fatty Liver - metabolism | Membrane Proteins - genetics | Liver - metabolism | Models, Molecular | Phospholipids - genetics | Hep G2 Cells | Mice, Knockout | Polymorphism, Genetic | Triglycerides - metabolism | Lysophospholipids - genetics | Animals | Cysteine Endopeptidases - genetics | Mice | Phosphatidic Acids - metabolism | Triglycerides - genetics | COS Cells | Physiological aspects | Medical colleges | Disease susceptibility | Liver diseases | Liver cirrhosis
Journal Article
Science Signaling, ISSN 1945-0877, 04/2018, Volume 11, Issue 527, p. eaai7838
The transient activation of inflammatory networks is required for adipose tissue remodeling including the "browning" of white fat in response to stimuli such... 
WHITE | ACTIVATION | INHIBITION | CONVERSION | THERMOGENIC ADIPOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | BROWN ADIPOCYTES | IN-VIVO | TRANSCRIPTIONAL CONTROL | ADIPOCYTE DIFFERENTIATION | RECEPTOR | CELL BIOLOGY | Janus Kinases - genetics | Adipocytes, Beige - metabolism | Humans | Mice, Inbred C57BL | Adipose Tissue - pathology | Cells, Cultured | Gene Expression Profiling | Janus Kinases - metabolism | Signal Transduction - genetics | Lipase - metabolism | Mice, Knockout | Adipose Tissue - metabolism | Cell Differentiation - genetics | Inflammation - metabolism | Animals | Transforming Growth Factor beta - genetics | Adipocytes, Beige - pathology | Inflammation - genetics | Female | Adipogenesis - genetics | Transforming Growth Factor beta - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Lipase - genetics | Animal models | Transcription factors | Adipose tissue | Adrenal glands | Crosstalk | Smooth muscle | Stimulation | Activation | Smad3 protein | Adipocytes | Remodeling | Kinases | Interleukin 6 | Signal transduction | Pathways | Inhibition | Adipogenesis | Repressing | Transforming growth factor-b1 | Cytokines | Therapeutic applications | Stat3 protein | Muscles | Interleukin 11 | Inflammation | Lipolysis | Signaling | Browning | Stromal cells | Adrenergic receptors | Receptor mechanisms | Differentiation | Life Sciences
Journal Article
Cell Reports, ISSN 2211-1247, 05/2018, Volume 23, Issue 7, pp. 1948 - 1961
Journal Article
Journal Article
CARDIOVASCULAR RESEARCH, ISSN 0008-6363, 02/2020, Volume 116, Issue 2, pp. 339 - 352
Aims: Lipotoxic cardiomyopathy in diabetic and obese patients typically encompasses increased cardiac fatty acid (FA) uptake eventually surpassing the... 
PPAR-ALPHA | CARDIAC & CARDIOVASCULAR SYSTEMS | HORMONE-SENSITIVE LIPASE | ATGL-MEDIATED LIPOLYSIS | Mitochondrial dynamics | Cardiac lipolysis | MUSCLE | DEPENDS | AUTOPHAGY | Perilipin 5 | OVEREXPRESSION | METABOLISM | STEATOSIS | Heart dysfunction | ACCUMULATION | Lipotoxicity
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2011, Volume 286, Issue 20, pp. 17467 - 17477
Journal Article