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1. Full Text Time for one-person trials
by Schork, Nicholas J
Nature (London), ISSN 0028-0836, 04/2015, Volume 520, Issue 7549, pp. 609 - 611
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Studies | Drugs | Medicine | Intervention | Regulatory agencies | Disease | Biomarkers | Clinical trials | Genetics | Pharmaceutical industry | Patients
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2. Full Text Personalized medicine: Time for one-person trials
by Schork, Nicholas J
Nature (London), ISSN 0028-0836, 04/2015, Volume 520, Issue 7549, pp. 609 - 611
Humans | Biomarkers - analysis | Pyrimidines - pharmacology | Sulfonamides - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Pharmacogenetics - trends | Sample Size | Clinical Trials as Topic - trends | Antibodies, Monoclonal, Humanized - pharmacology | Precision Medicine - trends | Indoles - pharmacology | Benzamides - pharmacology | Clinical Trials as Topic - methods | Cetuximab | Research Design | Precision Medicine - methods | Index Medicus
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3. Full Text Genome-wide association study identifies 30 loci associated with bipolar disorder
by Stahl, Eli A and Breen, Gerome and Forstner, Andreas J and McQuillin, Andrew and Ripke, Stephan and Trubetskoy, Vassily and Mattheisen, Manuel and Wang, Yunpeng and Coleman, Jonathan R. I and Gaspar, Héléna A and de Leeuw, Christiaan A and Steinberg, Stacy and Pavlides, Jennifer M. Whitehead and Trzaskowski, Maciej and Byrne, Enda M and Pers, Tune H and Holmans, Peter A and Richards, Alexander L and Abbott, Liam and Agerbo, Esben and Akil, Huda and Albani, Diego and Alliey-Rodriguez, Ney and Als, Thomas D and Anjorin, Adebayo and Antilla, Verneri and Awasthi, Swapnil and Badner, Judith A and Bækvad-Hansen, Marie and Barchas, Jack D and Bass, Nicholas and Bauer, Michael and Belliveau, Richard and Bergen, Sarah E and Pedersen, Carsten Bøcker and Bøen, Erlend and Boks, Marco P and Boocock, James and Budde, Monika and Bunney, William and Burmeister, Margit and Bybjerg-Grauholm, Jonas and Byerley, William and Casas, Miquel and Cerrato, Felecia and Cervantes, Pablo and Chambert, Kimberly and Charney, Alexander W and Chen, Danfeng and Churchhouse, Claire and Clarke, Toni-Kim and Coryell, William and Craig, David W and Cruceanu, Cristiana and Curtis, David and Czerski, Piotr M and Dale, Anders M and de Jong, Simone and Degenhardt, Franziska and Del-Favero, Jurgen and DePaulo, J. Raymond and Djurovic, Srdjan and Dobbyn, Amanda L and Dumont, Ashley and Elvsåshagen, Torbjørn and Escott-Price, Valentina and Fan, Chun Chieh and Fischer, Sascha B and Flickinger, Matthew and Foroud, Tatiana M and Forty, Liz and Frank, Josef and Fraser, Christine and Freimer, Nelson B and Frisén, Louise and Gade, Katrin and Gage, Diane and Garnham, Julie and Giambartolomei, Claudia and Pedersen, Marianne Giørtz and Goldstein, Jaqueline and Gordon, Scott D and Gordon-Smith, Katherine and Green, Elaine K and Green, Melissa J and Greenwood, Tiffany A and Grove, Jakob and Guan, Weihua and Guzman-Parra, José and Hamshere, Marian L and Hautzinger, Martin and Heilbronner, Urs and Herms, Stefan and Hipolito, Maria and Hoffmann, Per and Holland, Dominic and Huckins, Laura and Jamain, Stéphane and Johnson, Jessica S and Juréus, Anders and ... and Bipolar Disorder Working Grp Psych and eQTLGen Consortium and BIOS Consortium and Bipolar Disorder Working Group of the Psychiatric Genomics Consortium and the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium and Sahlgrenska akademin and Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi and Göteborgs universitet and Gothenburg University and Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry and Sahlgrenska Academy
Nature genetics, ISSN 1061-4036, 05/2019, Volume 51, Issue 5, pp. 793 - 803
Genetic Predisposition to Disease | Genome-Wide Association Study | Meta-Analysis | Humans | Male | Genetic Loci | Systems Biology | Case-Control Studies | Journal Article | Depressive Disorder, Major/genetics | Bipolar Disorder/classification | Research Support, N.I.H., Intramural | Research Support, Non-U.S. Gov't | Psychotic Disorders/genetics | Female | Genetics | Polymorphism, Single Nucleotide | Schizophrenia/genetics | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Bipolar Disorder - genetics | Bipolar Disorder - classification | Psychotic Disorders - genetics | Schizophrenia - genetics | Depressive Disorder, Major - genetics | Quantitative trait loci | Genome-wide association studies | Usage | Bipolar disorder | Genetic aspects | Identification and classification | Health aspects | Risk factors | Neurosciences | Genealogy | Working groups | Mental disorders | Secretion | Genomics | Neurobiology | Schizophrenia | Genomes | Mental depression | Gene expression | Insulin | Loci | Datasets | Psychosis | Studies | Consortia | Heterogeneity | Cannabinoids | Liability | Genetic analysis | Ion channels | Alzheimers disease | Index Medicus | Psykiatri | Psychiatry
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4. Full Text Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
by Elks, Cathy and Perry, John and Sulem, Patrick and Chasman, Daniel and Franceschini, Nora and He, Chunyan and Lunetta, Kathryn and Visser, Jenny and Byrne, Enda and Cousminer, Diana and Gudbjartsson, Daniel and Esko, Tõnu and Feenstra, Bjarke and Hottenga, Jouke Jan and Koller, Daniel and Kutalik, Zoltán and Lin, Peng and Mangino, Massimo and Marongiu, Mara and McArdle, Patrick and Smith, Albert Vernon and Stolk, Lisette and Wingerden, Sophie and Zhao, Jing Hua and Albrecht, Eva and Corre, Tanguy and Ingelsson, Erik and Hayward, Caroline and Magnusson, Patrik and Ulivi, Shelia and Warrington, Nicole and Zgaga, Lina and Alavere, Helene and Amin, Najaf and Aspelund, Thor and Bandinelli, Stefania and Barroso, Inês and Berenson, Gerald and Bergmann, Sven and Blackburn, Hannah and Boerwinkle, Eric and Buring, Julie and Busonero, F and Campbell, Harry and Chanock, Stephen and Chen, Wei and Cornelis, Marilyn and Couper, David and Coviello, Anea and Adamo, Pio and Faire, Ulf and Geus, Eco and Deloukas, Panagiotis and Döring, Angela and Easton, Douglas and Eiriksdottir, Gudny and Emilsson, Valur and Eriksson, Johan and Ferrucci, Luigi and Folsom, Aaron and Foroud, Tatiana and Garcia, Melissa and Gasparini, Paolo and Geller, Frank and Gieger, Christian and Gudnason, Vilmundur and Hall, Alistair and Hankinson, Susan and Ferreli, Liana and Heath, Anew and Hernandez, Dena and Hofman, Albert and Hu, Frank and Illig, Thomas and Järvelin, M.R and Johnson, Anew and Karasik, David and Khaw, Kay-Tee and Kiel, Douglas and Kilpelänen, Tuomas and Kolcic, Ivana and Kraft, Peter and Launer, Lenore and Laven, Joop and Li, Shengxu and Liu, Jianjun and Levy, Daniel and Martin, Nicholas and Melbye, Mads and Mooser, Vincent and Murray, Jeffrey and Nalls, Michael and Navarro, Pau and Nelis, Mari and Ness, Anew and Northstone, Kate and Oostra, Ben and Peacock, Munro and Palmer, Cameron and Palotie, Aarno and ... and GIANT Consortium and The GIANT Consortium
Nature genetics, ISSN 1061-4036, 12/2010, Volume 42, Issue 12, pp. 1077 - 1085
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Genetic Predisposition to Disease | Genome-Wide Association Study | Reproducibility of Results | Menarche - genetics | Humans | Genetic Loci - genetics | DNA Copy Number Variations - genetics | Obesity - genetics | Body Height - genetics | Aging - physiology | Time Factors | Adolescent | Inheritance Patterns - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Size - genetics | Child | Quantitative Trait Loci - genetics | Quantitative trait loci | Menstruation | Synthesis | Physiological aspects | Genetic aspects | Research | Fatty acids | Puberty | Genetics | Chromosomes | Meta-analysis | Index Medicus | Medicin och hälsovetenskap
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5. Full Text Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder
by Maier, Robert and Moser, Gerhard and Chen, Guo-Bo and Ripke, Stephan and Absher, Devin and Agartz, Ingrid and Akil, Huda and Amin, Farooq and Andreassen, Ole A and Anjorin, Adebayo and Anney, Richard and Arking, Dan E and Asherson, Philip and Azevedo, Maria H and Backlund, Lena and Badner, Judith A and Bailey, Anthony J and Banaschewski, Tobias and Barchas, Jack D and Barnes, Michael R and Barrett, Thomas B and Bass, Nicholas and Battaglia, Agatino and Bauer, Michael and Bayés, Mònica and Bellivier, Frank and Bergen, Sarah E and Berrettini, Wade and Betancur, Catalina and Bettecken, Thomas and Biederman, Joseph and Binder, Elisabeth B and Black, Donald W and Blackwood, Douglas H.R and Bloss, Cinnamon S and Boehnke, Michael and Boomsma, Dorret I and Breen, Gerome and Breuer, René and Bruggeman, Richard and Buccola, Nancy G and Buitelaar, Jan K and Bunney, William E and Buxbaum, Joseph D and Byerley, William F and Caesar, Sian and Cahn, Wiepke and Cantor, Rita M and Casas, Miguel and Chakravarti, Aravinda and Chambert, Kimberly and Choudhury, Khalid and Cichon, Sven and Cloninger, C. Robert and Collier, David A and Cook, Edwin H and Coon, Hilary and Cormand, Bru and Cormican, Paul and Corvin, Aiden and Coryell, William H and Craddock, Nicholas and Craig, David W and Craig, Ian W and Crosbie, Jennifer and Cuccaro, Michael L and Curtis, David and Czamara, Darina and Daly, Mark J and Datta, Susmita and Dawson, Geraldine and Day, Richard and De Geus, Eco J and Degenhardt, Franziska and Devlin, Bernie and Djurovic, Srdjan and Donohoe, Gary J and Doyle, Alysa E and Duan, Jubao and Dudbridge, Frank and Duketis, Eftichia and Ebstein, Richard P and Edenberg, Howard J and Elia, Josephine and Ennis, Sean and Etain, Bruno and Fanous, Ayman and Faraone, Stephen V and Farmer, Anne E and Ferrier, I. Nicol and Flickinger, Matthew and Fombonne, Eric and Foroud, Tatiana and Frank, Josef and Franke, Barbara and Fraser, Christine and Freedman, Robert and Freimer, Nelson B and Freitag, Christine M and Friedl, Marion and ... and Cross-Disorder Working Group of the Psychiatric Genomics Consortium and Psychiat Genomics Consortium and Institute of Neuroscience and Physiology and Sahlgrenska akademin and Göteborgs universitet and Gothenburg University and Sahlgrenska Academy and Institutionen för neurovetenskap och fysiologi
American journal of human genetics, ISSN 0002-9297, 02/2015, Volume 96, Issue 2, pp. 283 - 294
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Mental Disorders - genetics | Multifactorial Inheritance - genetics | Multivariate Analysis | Risk Assessment - methods | Genetics, Medical - methods | Schizophrenia - genetics | Depressive Disorder, Major - genetics | Humans | Polymorphism, Single Nucleotide - genetics | Linear Models | Bipolar Disorder - genetics | Genetic Testing - methods | Schizophrenia | Bipolar disorder | Risk factors | Major depressive disorder | Correlation analysis | Genetics | Mental depression | Comparative analysis | Index Medicus | Life Sciences | Neurons and Cognition | Report | POPULATION | INFORMATION | LOCI | Klinisk medicin | IDENTIFICATION | RESTRICTED MAXIMUM-LIKELIHOOD | Clinical Medicine | MODELS | AVERAGE | GENETIC RISK | SELECTION | TRAITS | GENOME-WIDE ASSOCIATION
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6. Full Text Randomized clinical trials and personalized medicine: A commentary on deaton and cartwright
by Schork, Nicholas J
Social science & medicine (1982), ISSN 0277-9536, 08/2018, Volume 210, pp. 71 - 73
Public, Environmental & Occupational Health | Social Sciences | Life Sciences & Biomedicine | Biomedical Social Sciences | Social Sciences, Biomedical | Science & Technology | Precision Medicine | Randomized Controlled Trials as Topic | Clinical trials | Index Medicus
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7. Full Text Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci
by Asselbergs, Folkert W and Guo, Yiran and van Iperen, Erik P. A and Sivapalaratnam, Suthesh and Tragante, Vinicius and Lanktree, Matthew B and Lange, Leslie A and Almoguera, Berta and Appelman, Yolande E and Barnard, John and Baumert, Jens and Beitelshees, Amber L and Bhangale, Tushar R and Chen, Yii-Der Ida and Gaunt, Tom R and Gong, Yan and Hopewell, Jemma C and Johnson, Toby and Kleber, Marcus E and Langaee, Taimour Y and Li, Mingyao and Li, Yun R and Liu, Kiang and McDonough, Caitrin W and Meijs, Matthijs F. L and Middelberg, Rita P. S and Musunuru, Kiran and Nelson, Christopher P and O'Connell, Jeffery R and Padmanabhan, Sandosh and Pankow, James S and Pankratz, Nathan and Rafelt, Suzanne and Rajagopalan, Ramakrishnan and Romaine, Simon P. R and Schork, Nicholas J and Shaffer, Jonathan and Shen, Haiqing and Smith, Erin N and Tischfield, Sam E and van der Most, Peter J and van Vliet-Ostaptchouk, Jana V and Verweij, Niek and Chen, Wei and Zwinderman, A. H and Bezzina, Connie R and Trip, Mieke D and Wilde, Arthur A. M and Hovingh, G. Kees and Kastelein, John J. P and LifeLines Cohort Study
American journal of human genetics, ISSN 0002-9297, 2012, Volume 91, Issue 5, pp. 823 - 838
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Medical genetics | Genome-Wide Association Study | Lipids - genetics | Humans | European Continental Ancestry Group | Genotype | Male | Cholesterol, HDL - genetics | Cholesterol, LDL - genetics | Phenotype | Lipids - blood | Sex Factors | Triglycerides - blood | Cholesterol, HDL - blood | Cholesterol, LDL - blood | Female | Polymorphism, Single Nucleotide | Triglycerides - genetics | Quantitative Trait Loci | Europeans | Usage | Genome-wide association studies | Genetic variation | Cholesterol, HDL | Multifactorial traits | Genetic aspects | Research | Health aspects | Genetic screening | Plasma | Genotype & phenotype | Lipids | Genes | Meta-analysis | Index Medicus | Medicinsk genetik | Basic Medicine | Medical Genetics | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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