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FRONTIERS IN IMMUNOLOGY, ISSN 1664-3224, 12/2017, Volume 8, p. 1759
Human autonomous VH/VL single-domain antibodies (sdAbs) are attractive therapeutic molecules, but often suffer from suboptimal stability, solubility and... 
synthetic antibody | H DOMAINS | BIOPHYSICAL PROPERTIES | CHARGED MUTATIONS | IMMUNOLOGY | VARIABLE DOMAINS | RECEPTOR 1 | BINDERS | protein engineering | COMPLEMENTARITY-DETERMINING REGIONS | phage display | SMALL RECOGNITION UNITS | single-domain antibody | AGGREGATION | human V-H/V-L | ENDOTHELIAL GROWTH-FACTOR
Journal Article
ChemBioChem, ISSN 1439-4227, 03/2011, Volume 12, Issue 5, pp. 654 - 654
Journal Article
Science, ISSN 0036-8075, 05/2017, Volume 356, Issue 6337, pp. 492 - 493
Global warming potentials (GWPs) have become an essential element of climate policy and are built into legal structures that regulate greenhouse gas emissions.... 
POLLUTANTS | MULTIDISCIPLINARY SCIENCES | POTENTIALS | Climate | Greenhouse effect | Climate effects | Environmental policy | Fuel consumption | Time | Emission control | Greenhouse gases | Environmental impact | Dilution | Hides | Tradeoffs | Fuel economy | Air pollution | Global warming | Blood pressure | Pollutants | Policies | Emission
Journal Article
1986, Advances in polymer science = Fortschritte der Hochpolymeren-Forschung, ISBN 9783540164227, Volume 79., 232
Book
Proceedings of the National Academy of Sciences, USA, ISSN 0027-8424, 05/2008, Volume 105, Issue 18, pp. 6566 - 6571
Gadd45 proteins are recognized as tumor and autoimmune suppressors whose expression can be induced by genotoxic stresses. These proteins are involved in cell... 
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2008, Volume 379, Issue 4, pp. 787 - 802
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2008, Volume 105, Issue 18, p. 6566
  Gadd45 proteins are recognized as tumor and autoimmune suppressors whose expression can be induced by genotoxic stresses. These proteins are involved in cell... 
Proteins | Cell growth | Cell cycle | Biochemistry | Crystal structure | Apoptosis
Journal Article
Biochemistry, ISSN 0006-2960, 03/2010, Volume 49, Issue 9, pp. 1931 - 1942
Many serine hydrolases catalyze perhydrolysis, file reversible formation of peracids from carboxylic acids and hydrogen peroxide. Recently. we showed that it... 
OXIDATION | REFINEMENT | ACTIVATION | CHLOROPEROXIDASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | HALOPEROXIDASES | ALPHA/BETA-HYDROLASE SUPERFAMILY | HYDROGEN-PEROXIDE | PERACETIC-ACID | 3,4-DIHYDROCOUMARIN HYDROLASE | EPOXIDATION | Biocatalysis | Mutagenesis, Site-Directed | Carboxylic Ester Hydrolases - chemistry | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Catalytic Domain - genetics | Crystallization | Models, Molecular | Crystallography, X-Ray | Acetic Acid - chemistry | Caproates - chemistry | Pseudomonas fluorescens - genetics | Hydrogen Peroxide - chemistry | Hydrolysis | Proline - genetics | Esters - chemistry | Pseudomonas fluorescens - enzymology | Amino Acid Substitution - genetics | Carboxylic Ester Hydrolases - genetics | Diffusion | Leucine - genetics | Lactones - chemistry | Usage | Hydrogen peroxide | Substitution reactions | Enzyme binding | Pseudomonas fluorescens | Esterases | Hydrogen bonding | X-ray crystallography | Analysis | Physiological aspects | Genetic aspects | Chemical properties | Structure | CARBONYLS | CATALYSIS | HYDROLASES | HYDROLYSIS | 08 HYDROGEN | ACETIC ACID | national synchrotron light source | MASS SPECTROSCOPY | ESTERASES | ALCOHOLS | OXYGEN | HYDROGEN | LACTONES | SERINE | HYDROGEN PEROXIDE | AMINO ACIDS | ENZYMES | PSEUDOMONAS | ESTERS | ACETATES | CARBOXYLIC ACIDS | DIFFUSION
Journal Article
Structure, ISSN 0969-2126, 04/2004, Volume 12, Issue 4, pp. 521 - 522
Journal Article
Acta Crystallographica Section D, ISSN 0907-4449, 07/2004, Volume 60, Issue 7, pp. 1237 - 1243
Journal Article
mAbs, ISSN 1942-0862, 10/2019, Volume 11, Issue 7, pp. 1300 - 1318
Solution stability is an important factor in the optimization of engineered biotherapeutic candidates such as monoclonal antibodies because of its possible... 
Aggregation | structure-aggregation relationship | single point mutation | native folding | prediction method | PROTEIN-PROTEIN | MEDICINE, RESEARCH & EXPERIMENTAL | DESIGN | X-RAY CRYSTALLOGRAPHY | EXCHANGE-MASS-SPECTROMETRY | MONOCLONAL-ANTIBODY | VISCOSITY | ULTRACENTRIFUGATION | AMINO-ACID-SEQUENCE | INTERFACE | Index Medicus
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 1993, Volume 230, Issue 2, pp. 575 - 591
A lipase from the fungus Geotrichum candidum is one of only three interfacially activated lipases whose structures have been reported to date. We have... 
Refinement | Interfacial activation | Lipase | Geotrichum | Crystal structure | Amino Acid Sequence | Thermodynamics | Models, Structural | Protein Structure, Secondary | Geotrichum - enzymology | Disulfides - analysis | Models, Molecular | Glycosylation | Software | Lipase - chemistry | X-Ray Diffraction - methods | Binding Sites
Journal Article
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