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The Lancet Neurology, ISSN 1474-4422, 12/2017, Volume 16, Issue 12, pp. 965 - 975
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2019, Volume 176, Issue 19, pp. 3775 - 3790
Background and Purpose Chronic liver diseases feature excessive collagen and matrix protein deposition or crosslinking that characterises fibrosis, leads to... 
Enzymes | Flow cytometry | Histone deacetylase | Stellate cells | Lymphoid cells | Liver diseases | Liver | Medical services | Collagens | Crosslinking | Inflammation | Proteins | Thioacetamide | Injury prevention | Immunology | Inhibitors | Collagen | Fibrosis | Histones | Attenuation | Matrix protein | Enzyme-linked immunosorbent assay | Immune system
Journal Article
by van Zaane, Bas and van Klei, Wilton A and Buhre, Wolfgang F and Bauer, Peter and Boerma, E. Christiaan and Hoeft, Aneas and Metnitz, Philipp and Moreno, Rui P and Pearse, Rupert and Pelosi, Paolo and Sander, Michael and Vallet, Benoit and Pettilä, Ville and Vincent, Jean-Louis and Rhodes, Anew and Moreno, Rui and Spies, Claudia and Hoste, Eric and Huyghens, Luc and Jacobs, Rita and van Mossevelde, Veerle and Opdenacker, Godelieve and Poelaert, Jan and Spapen, Herbert and Leleu, Kris and Rijckaert, Dirk and de Decker, Koen and Foubert, Luc and de Neve, Nikolaas and Biston, Patrick and Piagnerelli, Michael and Collin, Vincent and den Blauwen, Nadia and Clauwaert, Charlotte and de Crop, Luc and Verbeke, An and Derumeaux, Pieter and Gardin, Christophe and Kindt, Sebastiaan and Louage, Sofie and Verhamme, Bruno and wé, Patrick and Lahaye, Ingrid and Rosseel, Francis and Rutsaert, Robert and Vanlinthout, Luc and de Kock, Marc and Forget, Patrice and Georges, Pascal and Grosu, Irina and Kahn, David and Lois, Fernande and Momeni, Mona and Yemnga, Auey Pospiech Bernadette and Jadoul, Jean-Luc and Malbrain, Manu and Bosinceanu, Dana and Collard, Edith and Jorens, Philippe and Reyntiens, Dirk and Smitz, Carine and Vercauteren, Marcel and Fagnoul, David and van Obbergh, Luc and Goranović, Tatjana and Mazul-Sunko, Branka and Toplice, Krapinske and Oremuš, Krešimir and Bešlić, Gabrijela and Duzel, Viktor and Hauptman, Ada and Peremin, Sanja and Šribar, Anej and Župčić, Miroslav and Benčević, Josip and Brod, Slavonski and Mirković, Ivan and Šarić Bauer, Zlata and Belavić, Matija and Blažanin, Božidar and Lončarić Katušin, Mirjana and Brozović Krijan, Antonija and Mišković, Petar and Šimić-Korać, Nataša and Topić, Jasna and Žilić, Antonio and Žunić, Josip and Acan, Ivana and Adanić, Mirta and Ivanov, Nikola and Pavičić Šarić, Jaanka and Tomulić, Katarina and Visković, Nataša and Bošnjak, Silvana and Haršanji njančevic, Ivana and Kristek, Gordana and Kvolik, Slavica and Markić, Stela and Stojanovic Rakipovic, Aneja and Tot, Ozana Katarina and ... and European Soc Intensive Care Med and European Soc Anaesthesiology and European Surgical Outcomes Study (EuSOS) group for the Trials groups of the European Society of Intensive Care Medicine and the European Society of Anaesthesiology
European journal of anaesthesiology, ISSN 0265-0215, 2015, Volume 32, Issue 7, pp. 477 - 485
Journal Article
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 06/2019, Volume 15, Issue 6, pp. 556 - 556
Inhibition of the NLRP3 inflammasome is a promising strategy for the development of new treatments for inflammatory diseases. MCC950 is a potent and specific... 
ACTIVATION | MECHANISM | CLEAVAGE | BINDING | BIOCHEMISTRY & MOLECULAR BIOLOGY | Hydrolysis | Inhibition | ATP | Medical treatment | Inflammatory diseases
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 06/2010, Volume 87, Issue 6, pp. 1103 - 1114
Selective inhibitor studies in macrophages implicate class II HDAC enzymes in TLR‐mediated inflammatory pathways and class I HDACs as negative regulators.... 
SAHA | TLR | inflammation | histone deacetylase | HDAC6 | sepsis | Histone deacetylase | Sepsis | Inflammation | RHEUMATOID-ARTHRITIS | CELLS | ACTIVATION | CYCLOOXYGENASE-2 | PROINFLAMMATORY GENE-EXPRESSION | KAPPA-B | IMMUNOLOGY | PU.1 | CELL BIOLOGY | LIPOPOLYSACCHARIDE | HISTONE DEACETYLASE INHIBITORS | HEMATOLOGY | TRICHOSTATIN | Inflammation - pathology | Interleukin-12 Subunit p40 - genetics | Luciferases - metabolism | Male | RNA, Messenger - metabolism | Inflammation - metabolism | Chromatin Immunoprecipitation | Plasminogen Activator Inhibitor 1 - metabolism | Cyclooxygenase 2 - genetics | Inflammation Mediators - metabolism | Toll-Like Receptor 4 - agonists | Plasminogen Activator Inhibitor 1 - genetics | Hydroxamic Acids - pharmacology | Interleukin-12 Subunit p40 - metabolism | Enzyme-Linked Immunosorbent Assay | Histone Deacetylase 6 | Mice, Inbred C57BL | RNA, Messenger - genetics | Histone Deacetylases - chemistry | Inflammation - immunology | Macrophages - cytology | Reverse Transcriptase Polymerase Chain Reaction | Toll-Like Receptor 4 - metabolism | Blotting, Western | Mice, Knockout | Macrophages - metabolism | Animals | Cyclooxygenase 2 - metabolism | Lipopolysaccharides - pharmacology | Histone Deacetylase Inhibitors - pharmacology | Macrophages - drug effects | Mice | Histone Deacetylases - physiology
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 06/2019, Volume 33, Issue 6, pp. 7437 - 7450
Uropathogenic Escherichia coli (UPEC) is the major cause of urinary tract infections (UTIs). The multidrug-resistant E. coli sequence type 131 (ST131) clone is... 
ACTIVATION | PERSISTENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | UTI | NLRP3 INFLAMMASOME | PYROPTOSIS | CELL BIOLOGY | MURINE MODEL | IN-VITRO | inflammasome | ST131 | URINARY-TRACT | BIOLOGY | BLADDER | STRAIN | UPEC | alpha-hemolysin
Journal Article