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1. Full Text Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins
by Schuijers, Jurian and Clevers, Hans
The EMBO journal, ISSN 0261-4189, 06/2012, Volume 31, Issue 12, pp. 2685 - 2696
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Animals | Receptors, G-Protein-Coupled - metabolism | Signal Transduction | Models, Biological | Humans | Gene Expression Regulation | Adult | Stem Cells - physiology | Mice | Wnt Proteins - metabolism | Thrombospondins - metabolism | stem cells | Lgr5 | intestine | Focus Review | Wnt
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2. Full Text Adult mammalian stem cells: the role of Wnt, Lgr5 and R-spondins
by Schuijers, J and Clevers, H
The EMBO journal, ISSN 0261-4189, 2012, Volume 31, Issue 12, pp. 2685 - 2696
stem cells | Lgr5 | intestine | Wnt | Signal transduction | Mammals | Molecular biology | Stem cells | Colorectal cancer | Index Medicus
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3. Full Text Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF
by Schuijers, Jurian and Mokry, Michal and Hatzis, Pantelis and Cuppen, Edwin and Clevers, Hans
The EMBO journal, ISSN 0261-4189, 01/2014, Volume 33, Issue 2, pp. 146 - 56
Chromatin | beta Catenin | Humans | Transcriptional Activation | Cells, Cultured | Gene Expression Profiling | Wnt Proteins | Animals | Microarray Analysis | HEK293 Cells | TCF Transcription Factors | Mice | Binding Sites | β‐catenin | Wnt pathway | TCF | transcriptional regulation | ChIP‐Seq | β-catenin | ChIP-Seq | Transcriptional regulation | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Chromatin - metabolism | TCF Transcription Factors - physiology | Transcriptional Activation - genetics | beta Catenin - metabolism | Wnt Proteins - physiology | Transcription factors | Genomes | Genes | Binding sites | Deoxyribonucleic acid--DNA | Index Medicus
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4. Full Text Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes
by Dowen, Jill M and Fan, Zi Peng and Hnisz, Denes and Ren, Gang and Abraham, Brian J and Zhang, Lyndon N and Weintraub, Abraham S and Schuijers, Jurian and Lee, Tong Ihn and Zhao, Keji and Young, Richard A
Cell (Cambridge), ISSN 0092-8674, 10/2014, Volume 159, Issue 2, pp. 374 - 387
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Chromosomal Proteins, Non-Histone - metabolism | Cell Cycle Proteins - metabolism | Organ Specificity | Sequence Analysis, DNA | Pluripotent Stem Cells - metabolism | Animals | Chromatin Immunoprecipitation | CCCTC-Binding Factor | High-Throughput Nucleotide Sequencing | Mice | Chromosomes, Mammalian - metabolism | Genome | Repressor Proteins - metabolism | Genetic research | Embryonic stem cells | Genes | Genomics | Index Medicus
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5. Full Text Coactivator condensation at super-enhancers links phase separation and gene control
by Sabari, Benjamin R and Dall'Agnese, Alessandra and Boija, Ann and Klein, Isaac A and Coffey, Eliot L and Shrinivas, Krishna and Abraham, Brian J and Hannett, Nancy M and Zamudio, Alicia and Manteiga, John C and Li, Charles H and Guo, Yang E and Day, Daniel S and Schuijers, Jurian and Vasile, Eliza and Malik, Sohail and Hnisz, Denes and Lee, Tong Ihn and Cisse, Ibrahim I and Roeder, Robert G and Sharp, Phillip A and Chakraborty, Arup K and Young, Richard A
Science (American Association for the Advancement of Science), ISSN 0036-8075, 07/2018, Volume 361, Issue 6400, p. 379
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Embryonic Stem Cells - metabolism | NIH 3T3 Cells | Immunoprecipitation | Transcription Factors - chemistry | Fluorescence Recovery After Photobleaching | Humans | Molecular Imaging | Trans-Activators - chemistry | Cell Nucleus - metabolism | HEK293 Cells | Trans-Activators - genetics | Conserved Sequence | Nuclear Proteins - genetics | Mediator Complex Subunit 1 - chemistry | Mediator Complex Subunit 1 - metabolism | Serine - genetics | Nuclear Proteins - metabolism | Transcription Factors - genetics | Nuclear Proteins - chemistry | Serine - chemistry | Intrinsically Disordered Proteins - genetics | Enhancer Elements, Genetic - drug effects | Glycols - pharmacology | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Animals | Intrinsically Disordered Proteins - chemistry | Trans-Activators - metabolism | Mice | Cell Nucleus - drug effects | Mediator Complex Subunit 1 - genetics | Intrinsically Disordered Proteins - metabolism | Genetic research | Transcription factors | Genetic aspects | Research | Mammals | Chromatin | Nucleation | Transcription elongation | Genes | Gene regulation | Embryo cells | Fluorescence | Stem cell transplantation | Density | DNA-directed RNA polymerase | Cofactors | Complexity | Proteins | Nucleoli | Condensates | Clusters | Droplets | Hubs | Elongation | Deoxyribonucleic acid--DNA | Photobleaching | Amino acid sequence | Gene expression | Ribonucleic acid--RNA | Molecular chains | Organic chemistry | Enhancers | Properties (attributes) | Sensitivity | Inhibitors | Phase separation | Stem cells | Nuclei (cytology) | Protein interaction | Transcription initiation | Nuclear reactions | RNA polymerase II | Cancer | Index Medicus
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6. Full Text Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
by Huch, M and Bonfanti, P and Boj, S.F and Sato, T and Loomans, C.J and van de Wetering, M and Sojoodi, M and Li, V.S and Schuijers, J and Gracanin, A and Ringnalda, F and Begthel, H and Hamer, K and Mulder, J and van Es, J.H and de Koning, E and Vries, R.G.J and Heimberg, H and Clevers, H
The EMBO journal, ISSN 0261-4189, 2013, Volume 32, Issue 20, pp. 2708 - 2721
beta cell | duct cell | stem cell | Wnt | pancreas | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Adult Stem Cells - physiology | Cell Proliferation | Receptors, G-Protein-Coupled - metabolism | Thrombospondins - genetics | Embryo, Mammalian | Multipotent Stem Cells - metabolism | Pancreas - cytology | Cell Culture Techniques | Multipotent Stem Cells - physiology | Receptors, G-Protein-Coupled - physiology | Adult Stem Cells - cytology | Mice, Inbred C57BL | Cells, Cultured | Rats | Mice, Transgenic | Signal Transduction - genetics | Pancreas - metabolism | Mice, SCID | Rats, Sprague-Dawley | Adult Stem Cells - metabolism | Animals | Thrombospondins - physiology | Mice, Nude | Models, Biological | Multipotent Stem Cells - cytology | Mice | Receptors, G-Protein-Coupled - genetics | Thrombospondins - metabolism | Pancreas | Cell culture | Signal transduction | Index Medicus
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7. Full Text Erratum: Adult mammalian stem cells: The role of Wnt, Lgr5 and R-spondins (The EMBO Journal (2012) 31, (2685-2696) DOI:10.1038/emboj.2012.149)
by Schuijers, Jurian and Clevers, Hans
The EMBO journal, ISSN 0261-4189, 07/2012, Volume 31, Issue 13, pp. 3031 - 3032
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8. Full Text Coactivator condensation at super-enhancers links phase separation and gene control
by Sabari, Benjamin R and Dall'Agnese, Alessandra and Boija, Ann and Klein, Isaac A and Coffey, Eliot L and Shrinivas, Krishna and Abraham, Brian J and Hannett, Nancy M and Zamudio, Alicia V and Manteiga, John C and Li, Charles H and Guo, Yang E and Day, Daniel S and Schuijers, Jurian and Vasile, Eliza and Malik, Sohail and Hnisz, Denes and Lee, Tong Ihn and Cisse, Ibrahim I and Roeder, Robert G and Sharp, Phillip A and Chakraborty, Arup K and Young, Richard A
Science (American Association for the Advancement of Science), ISSN 0036-8075, 07/2018, Volume 361, Issue 6400
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9. Full Text Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism
by Schuijers, Jurian and Manteiga, John Colonnese and Weintraub, Abraham Selby and Day, Daniel Sindt and Zamudio, Alicia Viridiana and Hnisz, Denes and Lee, Tong Ihn and Young, Richard Allen
Cell reports (Cambridge), ISSN 2211-1247, 04/2018, Volume 23, Issue 2, pp. 349 - 360
enhancer docking | gene regulation | super-enhancers | chromosome structure | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Promoter Regions, Genetic | Cell Proliferation | Humans | Gene Expression Regulation, Neoplastic | CCCTC-Binding Factor - metabolism | CRISPR-Cas Systems - genetics | Proto-Oncogene Proteins c-myc - metabolism | Gene Editing | Amino Acid Motifs | DNA Methylation | Enhancer Elements, Genetic | Cell Line, Tumor | Protein Binding | Proto-Oncogene Proteins c-myc - genetics | Binding Sites | Index Medicus
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